JPWO2020244528A5 - - Google Patents
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- Publication number
- JPWO2020244528A5 JPWO2020244528A5 JP2021571970A JP2021571970A JPWO2020244528A5 JP WO2020244528 A5 JPWO2020244528 A5 JP WO2020244528A5 JP 2021571970 A JP2021571970 A JP 2021571970A JP 2021571970 A JP2021571970 A JP 2021571970A JP WO2020244528 A5 JPWO2020244528 A5 JP WO2020244528A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- seq
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910481112 | 2019-06-04 | ||
| CN201910481112.6 | 2019-06-04 | ||
| PCT/CN2020/094053 WO2020244528A1 (zh) | 2019-06-04 | 2020-06-03 | 一种抗ceacam5的单克隆抗体及其制备方法和用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022535553A JP2022535553A (ja) | 2022-08-09 |
| JP2022535553A5 JP2022535553A5 (https=) | 2023-06-12 |
| JPWO2020244528A5 true JPWO2020244528A5 (https=) | 2023-06-12 |
Family
ID=73652171
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571970A Pending JP2022535553A (ja) | 2019-06-04 | 2020-06-03 | 抗ｃｅａｃａｍ５モノクローナル抗体、その作製方法およびその使用 |
| JP2021572365A Active JP7554781B2 (ja) | 2019-06-04 | 2020-06-03 | 抗ｃｅａｃａｍ５モノクローナル抗体およびその調製方法およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021572365A Active JP7554781B2 (ja) | 2019-06-04 | 2020-06-03 | 抗ｃｅａｃａｍ５モノクローナル抗体およびその調製方法およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20220235142A1 (https=) |
| EP (1) | EP3981793A4 (https=) |
| JP (2) | JP2022535553A (https=) |
| KR (1) | KR20220016943A (https=) |
| CN (2) | CN113474372B (https=) |
| AU (1) | AU2020289301B2 (https=) |
| BR (1) | BR112021024544A2 (https=) |
| CA (1) | CA3142635A1 (https=) |
| TW (2) | TW202100560A (https=) |
| WO (2) | WO2020244526A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4305069A4 (en) * | 2021-03-08 | 2025-01-01 | University of Pittsburgh - of the Commonwealth System of Higher Education | MOLECULES THAT BIND TO CD66E POLYPEPTIDES |
| US12162940B2 (en) | 2021-05-05 | 2024-12-10 | Immatics Biotechnologies Gmbh | BMA031 antigen binding polypeptides |
| CN115505043A (zh) * | 2021-06-23 | 2022-12-23 | 上海吉倍生物技术有限公司 | 特异性结合糖基化ceacam5的抗体 |
| CN118159564A (zh) * | 2021-11-05 | 2024-06-07 | 信华生物药业(广州)有限公司 | 多特异性抗体及其用途 |
| CN116925232A (zh) * | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 靶向ceacam和cd3的多特异性抗体及其用途 |
| KR20250046323A (ko) * | 2022-08-10 | 2025-04-02 | 머크 샤프 앤드 돔 엘엘씨 | Nkg2d, cd16 및 ceacam5에 결합하는 단백질 |
| EP4642810A1 (en) * | 2022-12-28 | 2025-11-05 | Full-Life Technologies HK Limited | Antibodies specifically binding to ceacam5 |
| CN116376920A (zh) * | 2023-03-10 | 2023-07-04 | 中山大学附属第五医院 | Ceacam5靶向的car-t细胞的制备方法及应用 |
| EP4720134A1 (en) * | 2023-06-05 | 2026-04-08 | Nona Biosciences (Suzhou) Co., Ltd. | Anti-ceacam5/6 dual-binding antibodies |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| WO2025257185A1 (en) * | 2024-06-11 | 2025-12-18 | Abcely | Humanized anti-human-carcinoembryonic antigen antibody |
| CN118852441B (zh) * | 2024-08-30 | 2025-12-26 | 四川大学 | 一种抗ceacam5的纳米抗体及其相关应用 |
| CN119409833A (zh) * | 2024-10-25 | 2025-02-11 | 华道(上海)生物医药有限公司 | 一种抗ceacam5和ceacam6双靶向抗体及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
| AU701578B2 (en) | 1992-08-21 | 1999-02-04 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| WO1994025591A1 (en) | 1993-04-29 | 1994-11-10 | Unilever N.V. | PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE) |
| WO2005086875A2 (en) * | 2004-03-11 | 2005-09-22 | City Of Hope | A humanized anti-cea t84.66 antibody and uses thereof |
| GB0624500D0 (en) * | 2006-12-07 | 2007-01-17 | Istituto Superiore Di Sanito | A novel passive vaccine for candida infections |
| EP3009455A1 (en) * | 2009-09-16 | 2016-04-20 | Immunomedics Inc. | Class i anti-cea antibodies and uses thereof |
| WO2013054320A1 (en) * | 2011-10-11 | 2013-04-18 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam) |
| HUE033369T2 (en) * | 2012-11-20 | 2017-11-28 | Sanofi Sa | Anti-ceacam5 antibodies and uses thereof |
| US20150125386A1 (en) * | 2013-11-05 | 2015-05-07 | Immunomedics, Inc. | Humanized anti-ceacam5 antibody and uses thereof |
| CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| CA2968141C (en) * | 2015-01-16 | 2020-08-04 | Hsing-Mao CHU | Molecular constructs with targeting and effector elements |
| PT3274370T (pt) * | 2015-03-23 | 2020-01-30 | Bayer Pharma AG | Anticorpos anti-ceacam6 e utilizações dos mesmos |
| CN107708741A (zh) * | 2015-06-12 | 2018-02-16 | 免疫医疗公司 | 用嵌合抗原受体(car)构建体和表达car构建体的t细胞(car‑t)或nk细胞(car‑nk)进行的疾病疗法 |
| WO2017172981A2 (en) * | 2016-03-29 | 2017-10-05 | University Of Southern California | Chimeric antigen receptors targeting cancer |
| CN108341876B (zh) * | 2017-01-22 | 2021-06-04 | 中国人民解放军第四军医大学 | 抗人ceacam5单克隆抗体及其制备方法和应用 |
| TWI795415B (zh) * | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
-
2020
- 2020-06-03 US US17/616,399 patent/US20220235142A1/en not_active Abandoned
- 2020-06-03 CN CN202080016653.2A patent/CN113474372B/zh active Active
- 2020-06-03 TW TW109118591A patent/TW202100560A/zh unknown
- 2020-06-03 BR BR112021024544A patent/BR112021024544A2/pt unknown
- 2020-06-03 CN CN202080040435.2A patent/CN113906052B/zh active Active
- 2020-06-03 WO PCT/CN2020/094045 patent/WO2020244526A1/zh not_active Ceased
- 2020-06-03 JP JP2021571970A patent/JP2022535553A/ja active Pending
- 2020-06-03 AU AU2020289301A patent/AU2020289301B2/en active Active
- 2020-06-03 CA CA3142635A patent/CA3142635A1/en active Pending
- 2020-06-03 TW TW109118629A patent/TWI844684B/zh active
- 2020-06-03 US US17/596,183 patent/US20220242968A1/en active Pending
- 2020-06-03 WO PCT/CN2020/094053 patent/WO2020244528A1/zh not_active Ceased
- 2020-06-03 KR KR1020227000006A patent/KR20220016943A/ko active Pending
- 2020-06-03 EP EP20818729.4A patent/EP3981793A4/en active Pending
- 2020-06-03 JP JP2021572365A patent/JP7554781B2/ja active Active
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