JP2022535553A5 - - Google Patents

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Publication number
JP2022535553A5
JP2022535553A5 JP2021571970A JP2021571970A JP2022535553A5 JP 2022535553 A5 JP2022535553 A5 JP 2022535553A5 JP 2021571970 A JP2021571970 A JP 2021571970A JP 2021571970 A JP2021571970 A JP 2021571970A JP 2022535553 A5 JP2022535553 A5 JP 2022535553A5
Authority
JP
Japan
Prior art keywords
antibody
antigen
binding fragment
sequence
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021571970A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022535553A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2020/094053 external-priority patent/WO2020244528A1/zh
Publication of JP2022535553A publication Critical patent/JP2022535553A/ja
Publication of JP2022535553A5 publication Critical patent/JP2022535553A5/ja
Pending legal-status Critical Current

Links

JP2021571970A 2019-06-04 2020-06-03 抗ceacam5モノクローナル抗体、その作製方法およびその使用 Pending JP2022535553A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201910481112 2019-06-04
CN201910481112.6 2019-06-04
PCT/CN2020/094053 WO2020244528A1 (zh) 2019-06-04 2020-06-03 一种抗ceacam5的单克隆抗体及其制备方法和用途

Publications (2)

Publication Number Publication Date
JP2022535553A JP2022535553A (ja) 2022-08-09
JP2022535553A5 true JP2022535553A5 (https=) 2023-06-12

Family

ID=73652171

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021571970A Pending JP2022535553A (ja) 2019-06-04 2020-06-03 抗ceacam5モノクローナル抗体、その作製方法およびその使用
JP2021572365A Active JP7554781B2 (ja) 2019-06-04 2020-06-03 抗ceacam5モノクローナル抗体およびその調製方法およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021572365A Active JP7554781B2 (ja) 2019-06-04 2020-06-03 抗ceacam5モノクローナル抗体およびその調製方法およびその使用

Country Status (10)

Country Link
US (2) US20220242968A1 (https=)
EP (1) EP3981793A4 (https=)
JP (2) JP2022535553A (https=)
KR (1) KR20220016943A (https=)
CN (2) CN113906052B (https=)
AU (1) AU2020289301B2 (https=)
BR (1) BR112021024544A2 (https=)
CA (1) CA3142635A1 (https=)
TW (2) TWI844684B (https=)
WO (2) WO2020244528A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240166760A1 (en) * 2021-03-08 2024-05-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education MOLECULES THAT BIND TO CD66e POLYPEPTIDES
IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
CN115505043A (zh) * 2021-06-23 2022-12-23 上海吉倍生物技术有限公司 特异性结合糖基化ceacam5的抗体
US20240400715A1 (en) * 2021-11-05 2024-12-05 Vibrant Pharma Limited Multispecific antibodies and uses thereof
CN116925232A (zh) * 2022-04-02 2023-10-24 普米斯生物技术(珠海)有限公司 靶向ceacam和cd3的多特异性抗体及其用途
EP4569002A2 (en) * 2022-08-10 2025-06-18 Merck Sharp & Dohme LLC Proteins binding nkg2d, cd16, and ceacam5
EP4642810A1 (en) * 2022-12-28 2025-11-05 Full-Life Technologies HK Limited Antibodies specifically binding to ceacam5
CN116376920A (zh) * 2023-03-10 2023-07-04 中山大学附属第五医院 Ceacam5靶向的car-t细胞的制备方法及应用
WO2024250925A1 (en) * 2023-06-05 2024-12-12 Nona Biosciences (Suzhou) Co., Ltd. Anti-ceacam5 antibodies
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
WO2025257185A1 (en) * 2024-06-11 2025-12-18 Abcely Humanized anti-human-carcinoembryonic antigen antibody
CN118852441B (zh) * 2024-08-30 2025-12-26 四川大学 一种抗ceacam5的纳米抗体及其相关应用
CN119409833A (zh) * 2024-10-25 2025-02-11 华道(上海)生物医药有限公司 一种抗ceacam5和ceacam6双靶向抗体及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
ATE207080T1 (de) 1991-11-25 2001-11-15 Enzon Inc Multivalente antigen-bindende proteine
DK1621554T4 (da) 1992-08-21 2012-12-17 Univ Bruxelles Immunoglobuliner blottet for lette kæder
US6005079A (en) 1992-08-21 1999-12-21 Vrije Universiteit Brussels Immunoglobulins devoid of light chains
ES2162863T3 (es) 1993-04-29 2002-01-16 Unilever Nv Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
US7273608B2 (en) * 2004-03-11 2007-09-25 City Of Hope Humanized anti-CEA T84.66 antibody and uses thereof
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
EP2478110B1 (en) 2009-09-16 2016-01-06 Immunomedics, Inc. Class i anti-cea antibodies and uses thereof
WO2013054320A1 (en) * 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
DK3199552T3 (da) * 2012-11-20 2020-03-30 Sanofi Sa Anti-ceacam5-antistoffer og anvendelser heraf
CA2924398A1 (en) * 2013-11-05 2015-05-14 Immunomedics, Inc. Humanized anti-ceacam5 antibody and uses thereof
CA2874083C (en) * 2014-12-05 2024-01-02 Universite Laval Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases
TWI632160B (zh) * 2015-01-16 2018-08-11 中央研究院 具有標的部分及效應部分的分子構建體
PE20171790A1 (es) * 2015-03-23 2017-12-28 Bayer Pharma AG Anticuerpos anti-ceacam6 y sus usos
AU2016274989A1 (en) * 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
KR20230148844A (ko) * 2016-03-29 2023-10-25 유니버시티 오브 써던 캘리포니아 암을 표적하는 키메라 항원 수용체
CN108341876B (zh) * 2017-01-22 2021-06-04 中国人民解放军第四军医大学 抗人ceacam5单克隆抗体及其制备方法和应用
TWI795415B (zh) * 2017-07-07 2023-03-11 日商安斯泰來製藥股份有限公司 新穎的抗人類CEACAM5抗體Fab片段

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