JP2023543152A5 - - Google Patents

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Publication number
JP2023543152A5
JP2023543152A5 JP2023516061A JP2023516061A JP2023543152A5 JP 2023543152 A5 JP2023543152 A5 JP 2023543152A5 JP 2023516061 A JP2023516061 A JP 2023516061A JP 2023516061 A JP2023516061 A JP 2023516061A JP 2023543152 A5 JP2023543152 A5 JP 2023543152A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
acid sequence
antigen
binding molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023516061A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023543152A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/050850 external-priority patent/WO2022061098A1/en
Publication of JP2023543152A publication Critical patent/JP2023543152A/ja
Publication of JP2023543152A5 publication Critical patent/JP2023543152A5/ja
Pending legal-status Critical Current

Links

JP2023516061A 2020-09-18 2021-09-17 Cd38及び/又はcd28を結合する抗原結合分子及びその使用 Pending JP2023543152A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063080172P 2020-09-18 2020-09-18
US63/080,172 2020-09-18
PCT/US2021/050850 WO2022061098A1 (en) 2020-09-18 2021-09-17 Antigen-binding molecules that bind cd38 and/or cd28, and uses thereof

Publications (2)

Publication Number Publication Date
JP2023543152A JP2023543152A (ja) 2023-10-13
JP2023543152A5 true JP2023543152A5 (https=) 2025-09-30

Family

ID=78135158

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023516061A Pending JP2023543152A (ja) 2020-09-18 2021-09-17 Cd38及び/又はcd28を結合する抗原結合分子及びその使用

Country Status (12)

Country Link
US (2) US11905332B2 (https=)
EP (1) EP4214234A1 (https=)
JP (1) JP2023543152A (https=)
KR (1) KR20230070259A (https=)
CN (1) CN116348495A (https=)
AU (1) AU2021345262A1 (https=)
CA (1) CA3191839A1 (https=)
CL (3) CL2023000761A1 (https=)
CO (1) CO2023004448A2 (https=)
IL (1) IL301037A (https=)
MX (1) MX2023003214A (https=)
WO (1) WO2022061098A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL279354B1 (en) * 2018-06-21 2026-02-01 Regeneron Pharma Bispecific antibodies against psma and against cd28 and their uses
CA3192204A1 (en) 2020-08-19 2022-02-24 Xencor, Inc. Anti-cd28 and/or anti-b7h3 compositions
MX2023003214A (es) 2020-09-18 2023-05-24 Regeneron Pharma Moleculas de union al antigeno que se unen a cd38 y/o cd28 y usos de las mismas.
EP4320156A1 (en) 2021-04-09 2024-02-14 Ose Immunotherapeutics Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
US12365743B2 (en) 2022-02-23 2025-07-22 Xencor, Inc. Anti-CD28 x anti-PSMA antibodies
US20230416396A1 (en) * 2022-05-18 2023-12-28 Regeneron Pharmaceuticals, Inc. Multispecific antigen binding molecules that bind cd38 and 4-1bb, and uses thereof
US20240228620A1 (en) 2022-10-06 2024-07-11 Bicara Therapeutics Inc. Multispecific proteins and related methods
WO2025027003A1 (en) * 2023-07-31 2025-02-06 Sanofi Methods and uses for anti-cd38 t cell engagers in treatment of peripheral t-cell lymphomas
WO2025026356A1 (zh) * 2023-07-31 2025-02-06 百奥泰生物制药股份有限公司 靶向肿瘤相关抗原与cd28的双特异性抗体及其应用
CN117054649A (zh) * 2023-08-04 2023-11-14 广州中医药大学第一附属医院 一种慢性萎缩性胃炎向胃癌转化标志物及其应用
CN119101160B (zh) * 2024-10-25 2025-02-11 江苏百英生物科技有限公司 一种抗cd28纳米抗体、基于天然库筛选cd28纳米抗体的方法及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
JP5307708B2 (ja) 2006-06-02 2013-10-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド ヒトil−6受容体に対する高親和性抗体
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
MY192182A (en) 2009-06-26 2022-08-04 Regeneron Pharma Readily isolated bispecific antibodies with native immunoglobulin format
SMT202600080T1 (it) 2010-02-08 2026-03-09 Regeneron Pharma Topo con catena leggera comune
JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
TWI635098B (zh) 2013-02-01 2018-09-11 再生元醫藥公司 含嵌合恆定區之抗體
TWI681969B (zh) 2014-01-23 2020-01-11 美商再生元醫藥公司 針對pd-1的人類抗體
CA2874083C (en) * 2014-12-05 2024-01-02 Universite Laval Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases
CA3020633A1 (en) * 2016-04-13 2017-10-19 Sanofi Trispecific and/or trivalent binding proteins
JP7267914B2 (ja) 2016-11-02 2023-05-02 エンクマフ エスアーエールエル Bcma及びcd3に対する二重特異性抗体、及び多発性骨髄腫を治療するために併用して使用される免疫療法薬
US20200179511A1 (en) * 2017-04-28 2020-06-11 Novartis Ag Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
BR112020007002A2 (pt) * 2017-10-10 2020-11-17 Sanofi anticorpos anti-cd38 e métodos de uso
IL279354B1 (en) * 2018-06-21 2026-02-01 Regeneron Pharma Bispecific antibodies against psma and against cd28 and their uses
TWI838389B (zh) 2018-07-19 2024-04-11 美商再生元醫藥公司 雙特異性抗-BCMAx抗-CD3抗體及其用途
MA54540A (fr) * 2018-12-19 2021-10-27 Regeneron Pharma Anticorps anti-cd28 x anti-cd22 bispécifiques et leurs utilisations
US11453721B2 (en) * 2018-12-19 2022-09-27 Regeneran Pharmaceuticals, Inc. Bispecific anti-MUC16 x anti-CD28 antibodies and uses thereof
UA128001C2 (uk) * 2018-12-21 2024-03-06 Ф. Хоффманн-Ля Рош Аг Націлені на пухлину агоністичні cd28-антигензв'язувальні молекули
MX2023003214A (es) 2020-09-18 2023-05-24 Regeneron Pharma Moleculas de union al antigeno que se unen a cd38 y/o cd28 y usos de las mismas.

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