JP2024532836A5 - - Google Patents

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Publication number
JP2024532836A5
JP2024532836A5 JP2024509425A JP2024509425A JP2024532836A5 JP 2024532836 A5 JP2024532836 A5 JP 2024532836A5 JP 2024509425 A JP2024509425 A JP 2024509425A JP 2024509425 A JP2024509425 A JP 2024509425A JP 2024532836 A5 JP2024532836 A5 JP 2024532836A5
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JP
Japan
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JP2024509425A
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Japanese (ja)
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JP2024532836A (ja
JPWO2023020625A5 (https=
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Publication date
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Priority claimed from PCT/CN2022/113882 external-priority patent/WO2023020625A1/zh
Publication of JP2024532836A publication Critical patent/JP2024532836A/ja
Publication of JPWO2023020625A5 publication Critical patent/JPWO2023020625A5/ja
Publication of JP2024532836A5 publication Critical patent/JP2024532836A5/ja
Pending legal-status Critical Current

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JP2024509425A 2021-08-20 2022-08-22 抗TIGIT抗体及びTGF-βRを含む融合タンパク質、並びにその医薬組成物及び使用 Pending JP2024532836A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110961038 2021-08-20
CN202110961038.5 2021-08-20
PCT/CN2022/113882 WO2023020625A1 (zh) 2021-08-20 2022-08-22 包含抗TIGIT抗体和TGF-βR的融合蛋白、其药物组合物及用途

Publications (3)

Publication Number Publication Date
JP2024532836A JP2024532836A (ja) 2024-09-10
JPWO2023020625A5 JPWO2023020625A5 (https=) 2024-11-12
JP2024532836A5 true JP2024532836A5 (https=) 2024-11-12

Family

ID=85239528

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024509425A Pending JP2024532836A (ja) 2021-08-20 2022-08-22 抗TIGIT抗体及びTGF-βRを含む融合タンパク質、並びにその医薬組成物及び使用

Country Status (11)

Country Link
US (1) US20250319169A2 (https=)
EP (1) EP4389771A4 (https=)
JP (1) JP2024532836A (https=)
KR (1) KR20240046905A (https=)
CN (1) CN116003625A (https=)
AU (1) AU2022330896A1 (https=)
CA (1) CA3229166A1 (https=)
IL (1) IL310541A (https=)
MX (1) MX2024002147A (https=)
WO (1) WO2023020625A1 (https=)
ZA (1) ZA202401813B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021372706A1 (en) * 2020-10-26 2023-06-08 Akeso Biopharma, Inc. Anti-tigit antibody, and pharmaceutical composition and use thereof
JP2026508210A (ja) * 2023-02-20 2026-03-10 中山康方生物医▲藥▼有限公司 TGF-βRII細胞外領域断片を含む融合タンパク質、その医薬組成物、およびその使用
CN119613559B (zh) * 2023-09-14 2026-01-02 中山康方生物医药有限公司 药物组合及用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JO3096B1 (ar) * 2008-11-07 2017-03-15 Imclone Llc الأجسام المضادة لمستقبل ii مضاد tgfb
CN107207594B (zh) * 2014-12-23 2019-05-07 百时美施贵宝公司 针对tigit的抗体
EP3349792A1 (en) * 2015-09-14 2018-07-25 Compass Therapeutics LLC Compositions and methods for treating cancer via antagonism of the cd155/tigit pathway and tgf-
CA2994858C (en) * 2015-09-25 2024-01-23 Genentech, Inc. Anti-tigit antibodies and methods of use
JP7068169B2 (ja) * 2016-01-08 2022-05-16 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 条件付活性ヘテロ二量体ポリペプチド及びその使用方法
WO2017152088A1 (en) * 2016-03-04 2017-09-08 JN Biosciences, LLC Antibodies to tigit
AU2018264455B2 (en) * 2017-05-12 2024-12-12 Jiangsu Hengrui Medicine Co., Ltd. Fusion protein containing TGF-beta receptor and medicinal uses thereof
US11512129B2 (en) * 2017-09-29 2022-11-29 Jiangsu Hengrui Medicine Co., Ltd. TIGIT antibody, antigen-binding fragment thereof, and medical use thereof
JP7348899B2 (ja) * 2017-12-08 2023-09-21 マレンゴ・セラピューティクス,インコーポレーテッド 多重特異性分子及びその使用
KR20200109313A (ko) * 2018-01-15 2020-09-22 난징 레전드 바이오테크 씨오., 엘티디. Tigit에 대한 항체 및 이의 변이체
CN114555099A (zh) * 2019-06-23 2022-05-27 广东天科雅生物医药科技有限公司 抗alpp car-t细胞疗法
EP4054633A1 (en) * 2019-11-05 2022-09-14 Merck Patent GmbH Combined inhibition of pd-1, tgfb and tigit for the treatment of cancer
WO2021093760A1 (zh) * 2019-11-12 2021-05-20 江苏恒瑞医药股份有限公司 含有TGF-β受体的融合蛋白及其医药用途
US20220409684A1 (en) * 2019-11-18 2022-12-29 The Brigham And Women's Hospital, Inc. Codon optimized new generation regulatable fusogenic oncolytic herpes simplex virus type 1 virus and methods of use
AU2021372706A1 (en) * 2020-10-26 2023-06-08 Akeso Biopharma, Inc. Anti-tigit antibody, and pharmaceutical composition and use thereof
CN114106182B (zh) * 2022-01-26 2022-05-17 中山康方生物医药有限公司 抗tigit的抗体及其用途
CN114181310B (zh) * 2022-02-14 2022-07-05 中山康方生物医药有限公司 抗tigit抗体、其药物组合物及用途

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