JPWO2020227097A5 - - Google Patents
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- Publication number
- JPWO2020227097A5 JPWO2020227097A5 JP2021564996A JP2021564996A JPWO2020227097A5 JP WO2020227097 A5 JPWO2020227097 A5 JP WO2020227097A5 JP 2021564996 A JP2021564996 A JP 2021564996A JP 2021564996 A JP2021564996 A JP 2021564996A JP WO2020227097 A5 JPWO2020227097 A5 JP WO2020227097A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- epilepsy
- group
- formula
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962842855P | 2019-05-03 | 2019-05-03 | |
| US201962842861P | 2019-05-03 | 2019-05-03 | |
| US201962842858P | 2019-05-03 | 2019-05-03 | |
| US62/842,861 | 2019-05-03 | ||
| US62/842,858 | 2019-05-03 | ||
| US62/842,855 | 2019-05-03 | ||
| US202062982858P | 2020-02-28 | 2020-02-28 | |
| US62/982,858 | 2020-02-28 | ||
| PCT/US2020/031039 WO2020227097A1 (en) | 2019-05-03 | 2020-05-01 | Kcnt1 inhibitors and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022530989A JP2022530989A (ja) | 2022-07-05 |
| JPWO2020227097A5 true JPWO2020227097A5 (es) | 2023-05-11 |
Family
ID=73050875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564996A Pending JP2022530989A (ja) | 2019-05-03 | 2020-05-01 | Ｋｃｎｔ１阻害剤および使用する方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20220280476A1 (es) |
| EP (1) | EP3962479A4 (es) |
| JP (1) | JP2022530989A (es) |
| KR (1) | KR20220016469A (es) |
| CN (1) | CN114206335A (es) |
| AU (1) | AU2020267355A1 (es) |
| BR (1) | BR112021022061A2 (es) |
| CA (1) | CA3139062A1 (es) |
| CL (1) | CL2021002876A1 (es) |
| CO (1) | CO2021016469A2 (es) |
| EC (1) | ECSP21087657A (es) |
| IL (1) | IL287751A (es) |
| MX (1) | MX2021013422A (es) |
| PE (1) | PE20220017A1 (es) |
| SG (1) | SG11202112212WA (es) |
| WO (1) | WO2020227097A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7066871B2 (ja) | 2017-12-15 | 2022-05-13 | シロニックス リニューアブルス，インコーポレイティド | 界面活性剤を形成するための反応性蒸留 |
| WO2020014304A1 (en) | 2018-07-12 | 2020-01-16 | Sironix Renewables, Llc | Surfactants from long-chain carbon-containing molecules |
| KR20220016469A (ko) * | 2019-05-03 | 2022-02-09 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| WO2021225932A1 (en) * | 2020-05-04 | 2021-11-11 | Sironix Renewables, Inc. | Furan surfactant compositions and methods |
| US11773088B2 (en) | 2020-11-02 | 2023-10-03 | Praxis Precision Medicines, Inc. | KCNT1 inhibitors and methods of use |
| EP4267133A2 (en) * | 2020-12-22 | 2023-11-01 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| WO2022231872A1 (en) * | 2021-04-29 | 2022-11-03 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| WO2023211855A1 (en) * | 2022-04-25 | 2023-11-02 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising a thiophene core and methods of use |
| WO2024123717A1 (en) * | 2022-12-05 | 2024-06-13 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising a phenyl, pyridine, or pyrimidine core and methods of use |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19929076A1 (de) * | 1999-06-25 | 2000-12-28 | Aventis Pharma Gmbh | Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| AU5464901A (en) * | 2000-03-01 | 2001-09-12 | Nihon Bayer Agrochem K.K. | Dichloropyridyl- and dichloroisothiazolyl-thiocarboxamides and their use as microbicides |
| TWI243164B (en) * | 2001-02-13 | 2005-11-11 | Aventis Pharma Gmbh | Acylated indanyl amines and their use as pharmaceuticals |
| WO2005066137A1 (en) * | 2003-12-19 | 2005-07-21 | Neurogen Corporation | 2,5-diaryl-1h-imidazole-4-carboxamides as neurokinin-3 receptor modulators for the treatment of central nervous system and peripheral diseases |
| KR20070092297A (ko) * | 2004-12-21 | 2007-09-12 | 데브젠 엔브이 | Ｋｖ4 이온 채널 활성을 갖는 화합물 |
| EP3638790A4 (en) * | 2017-06-13 | 2021-03-10 | The Florey Institute Of Neuroscience And Mental Health | COMPOSITIONS AND METHODS FOR DEALING WITH CONDITIONS ASSOCIATED WITH FUNCTION GAIN MUTATIONS IN KCNT1 |
| MA51620A (fr) * | 2018-01-19 | 2020-11-25 | Cytokinetics Inc | Analogues de dihydrobenzofurane et d'inden en tant qu'inhibiteurs de sarcomes cardiaques |
| CN108517358A (zh) * | 2018-04-09 | 2018-09-11 | 重庆医科大学附属第医院 | 一种辅助癫痫诊断的标志物及其检测试剂盒 |
| KR20220016469A (ko) * | 2019-05-03 | 2022-02-09 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
-
2020
- 2020-05-01 KR KR1020217039175A patent/KR20220016469A/ko unknown
- 2020-05-01 EP EP20802501.5A patent/EP3962479A4/en active Pending
- 2020-05-01 US US17/607,815 patent/US20220280476A1/en active Pending
- 2020-05-01 WO PCT/US2020/031039 patent/WO2020227097A1/en active Application Filing
- 2020-05-01 SG SG11202112212WA patent/SG11202112212WA/en unknown
- 2020-05-01 AU AU2020267355A patent/AU2020267355A1/en active Pending
- 2020-05-01 JP JP2021564996A patent/JP2022530989A/ja active Pending
- 2020-05-01 CN CN202080047481.5A patent/CN114206335A/zh active Pending
- 2020-05-01 BR BR112021022061A patent/BR112021022061A2/pt unknown
- 2020-05-01 CA CA3139062A patent/CA3139062A1/en active Pending
- 2020-05-01 PE PE2021001829A patent/PE20220017A1/es unknown
- 2020-05-01 MX MX2021013422A patent/MX2021013422A/es unknown
-
2021
- 2021-11-01 IL IL287751A patent/IL287751A/en unknown
- 2021-11-02 CL CL2021002876A patent/CL2021002876A1/es unknown
- 2021-12-02 EC ECSENADI202187657A patent/ECSP21087657A/es unknown
- 2021-12-02 CO CONC2021/0016469A patent/CO2021016469A2/es unknown
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