JPWO2020223445A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020223445A5
JPWO2020223445A5 JP2021564537A JP2021564537A JPWO2020223445A5 JP WO2020223445 A5 JPWO2020223445 A5 JP WO2020223445A5 JP 2021564537 A JP2021564537 A JP 2021564537A JP 2021564537 A JP2021564537 A JP 2021564537A JP WO2020223445 A5 JPWO2020223445 A5 JP WO2020223445A5
Authority
JP
Japan
Prior art keywords
seq
sequence
amino acid
acid sequence
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021564537A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022530542A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/030640 external-priority patent/WO2020223445A1/en
Publication of JP2022530542A publication Critical patent/JP2022530542A/ja
Publication of JPWO2020223445A5 publication Critical patent/JPWO2020223445A5/ja
Pending legal-status Critical Current

Links

JP2021564537A 2019-04-30 2020-04-30 キメラ受容体及びその使用方法 Pending JP2022530542A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962841128P 2019-04-30 2019-04-30
US62/841,128 2019-04-30
US201962854151P 2019-05-29 2019-05-29
US62/854,151 2019-05-29
US201962893106P 2019-08-28 2019-08-28
US62/893,106 2019-08-28
PCT/US2020/030640 WO2020223445A1 (en) 2019-04-30 2020-04-30 Chimeric receptors and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2022530542A JP2022530542A (ja) 2022-06-29
JPWO2020223445A5 true JPWO2020223445A5 (ru) 2023-05-01

Family

ID=73029309

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021564537A Pending JP2022530542A (ja) 2019-04-30 2020-04-30 キメラ受容体及びその使用方法

Country Status (10)

Country Link
EP (1) EP3962527A4 (ru)
JP (1) JP2022530542A (ru)
KR (1) KR20220016083A (ru)
CN (1) CN114007642A (ru)
AU (1) AU2020265679A1 (ru)
CA (1) CA3133333A1 (ru)
IL (1) IL287407A (ru)
SG (1) SG11202111130SA (ru)
TW (1) TW202110873A (ru)
WO (1) WO2020223445A1 (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220289842A1 (en) * 2019-08-20 2022-09-15 Senti Biosciences, Inc. Chimeric inhibitory receptor
IL302728A (en) * 2020-11-13 2023-07-01 Catamaran Bio Inc Genetically modified natural killer cells and methods of using them
WO2022115565A2 (en) * 2020-11-24 2022-06-02 Senti Biosciences, Inc. Chimeric receptors and methods of use thereof
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
JP2024500847A (ja) 2020-12-18 2024-01-10 センチュリー セラピューティクス,インコーポレイテッド 適合可能な受容体特異性を有するキメラ抗原受容体システム
EP4334346A2 (en) * 2021-05-07 2024-03-13 Senti Biosciences, Inc. Chimeric receptors and methods of use thereof
AU2022324040A1 (en) 2021-08-04 2024-02-22 The Regents Of The University Of Colorado, A Body Corporate Lat activating chimeric antigen receptor t cells and methods of use thereof
CN113980907B (zh) * 2021-12-24 2022-03-15 山东兴瑞生物科技有限公司 一种抗flt3嵌合抗原受体修饰的t细胞及其在制备治疗aml药物中的应用
CN114645022B (zh) * 2022-05-13 2022-09-02 首都医科大学宣武医院 靶向CD5的CAR-γ δ T细胞及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322547A1 (en) * 2003-06-25 2011-05-18 Crucell Holland B.V. Myeloid cell-specific lectin
AR071891A1 (es) * 2008-05-30 2010-07-21 Imclone Llc Anticuerpos humanos anti-flt3 (receptor tirosina cinasa 3 tipo fms humano)
CA3060520C (en) * 2012-10-12 2022-05-17 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
EP4205749A1 (en) * 2014-07-31 2023-07-05 Novartis AG Subset-optimized chimeric antigen receptor-containing cells
US11655452B2 (en) * 2015-06-25 2023-05-23 Icell Gene Therapeutics Inc. Chimeric antigen receptors (CARs), compositions and methods of use thereof
AU2017279548A1 (en) * 2016-06-08 2018-12-13 Precigen, Inc. Cd33 specific chimeric antigen receptors
EP3474867A4 (en) * 2016-06-24 2020-05-20 iCell Gene Therapeutics LLC CHIMERIC ANTIGEN (CAR) RECEPTORS, COMPOSITIONS AND RELATED METHODS
AU2018288814A1 (en) * 2017-06-21 2020-02-06 Icell Gene Therapeutics Llc Chimeric antigen receptors (CARs), compositions and methods thereof
CA3071303A1 (en) * 2017-08-01 2019-02-07 Julius-Maximilians-Universitat Wurzburg Use of flt3 car-t cells and flt3 inhibitors to treat acute myeloid leukemia
AU2018347601A1 (en) * 2017-10-12 2020-04-23 Icell Gene Therapeutics, Llc Compound chimeric antigen receptor (cCAR) targeting multiple antigens, compositions and methods of use thereof

Similar Documents

Publication Publication Date Title
US10793638B2 (en) Use of chimeric antigen receptor modified cells to treat cancer
JP6919091B2 (ja) Gタンパク質共役受容体を標的化するキメラ抗原受容体およびその使用
US20230140802A1 (en) Novel platforms for co-stimulation, novel car designs and other enhancements for adoptive cellular therapy
US9828425B2 (en) Anti-ILT5 antibodies and ILT5-binding antibody fragments
DE69433820T2 (de) Verwendung von löslichen oligomerischen cd40 liganden oder monoklonalen antikörpern zur herstellung eines arzneimitells zur vorbeugung oder behandlung von neoplastischen krankheiten
JP2021535756A (ja) 単一ドメイン抗体に基づくbcmaキメラ抗原受容体及びその使用
KR20190034588A (ko) 키메라 항원 수용체 및 pd-1 억제제의 조합 요법
US9534051B2 (en) Immunoregulation by anti-ILT5 antibodies and ILT5-binding antibody fragments
JP2017537629A5 (ru)
JP2020530989A5 (ru)
CA3032146A1 (en) Identification of vsig3/vista as a novel immune checkpoint and use thereof for immunotherapy
JP2018533371A5 (ru)
US11840575B2 (en) Engineered immune cells targeting BCMA and their uses thereof
JP2019527696A5 (ru)
CA3177829A1 (en) Chimeric antigen and t cell receptors and methods of use
JP7358369B2 (ja) Cd83結合キメラ抗原受容体
JP7252651B2 (ja) Cd33発現がんを標的とするための組成物および方法
US10654934B2 (en) Use of chimeric antigen receptor modified cells to treat cancer
JPWO2020223445A5 (ru)
KR20240037892A (ko) 클라우딘 18.2 t 세포-항원 커플러 및 이의 용도
WO2018064921A1 (en) Use of chimeric antigen receptor modified cells to treat cancer
US20230172923A1 (en) Methods of treating cytokine-related adverse events
US20210095036A1 (en) Humanized Anti-GDNF family alpha-receptor 4 (GRF-alpha-4) Antibodies and Chimeric Antigen Receptors (CARs)
CA3228566A1 (en) Anti-her2 car nk cells, methods of their production and uses thereof
JPWO2021168317A5 (ru)