JPWO2020190774A5 - - Google Patents

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Publication number
JPWO2020190774A5
JPWO2020190774A5 JP2021555405A JP2021555405A JPWO2020190774A5 JP WO2020190774 A5 JPWO2020190774 A5 JP WO2020190774A5 JP 2021555405 A JP2021555405 A JP 2021555405A JP 2021555405 A JP2021555405 A JP 2021555405A JP WO2020190774 A5 JPWO2020190774 A5 JP WO2020190774A5
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JP
Japan
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alkyl
alkylenyl
haloalkyl
halogen
unsubstituted
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Pending
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JP2021555405A
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English (en)
Japanese (ja)
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JP2022525186A (ja
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Priority claimed from PCT/US2020/022757 external-priority patent/WO2020190774A1/en
Publication of JP2022525186A publication Critical patent/JP2022525186A/ja
Priority to JP2023076091A priority Critical patent/JP2023113615A/ja
Publication of JPWO2020190774A5 publication Critical patent/JPWO2020190774A5/ja
Pending legal-status Critical Current

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JP2021555405A 2019-03-15 2020-03-13 Ｔｅａｄ転写因子新規小分子阻害剤 Pending JP2022525186A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023076091A JP2023113615A (ja) 2019-03-15 2023-05-02 Ｔｅａｄ転写因子の新規小分子阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962819347P 2019-03-15 2019-03-15
US62/819,347 2019-03-15
PCT/US2020/022757 WO2020190774A1 (en) 2019-03-15 2020-03-13 Novel small molecule inhibitors of tead transcription factors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023076091A Division JP2023113615A (ja) 2019-03-15 2023-05-02 Ｔｅａｄ転写因子の新規小分子阻害剤

Publications (2)

Publication Number Publication Date
JP2022525186A JP2022525186A (ja) 2022-05-11
JPWO2020190774A5 true JPWO2020190774A5 (ko) 2023-05-22

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ID=72520559

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021555405A Pending JP2022525186A (ja) 2019-03-15 2020-03-13 Ｔｅａｄ転写因子新規小分子阻害剤
JP2023076091A Pending JP2023113615A (ja) 2019-03-15 2023-05-02 Ｔｅａｄ転写因子の新規小分子阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023076091A Pending JP2023113615A (ja) 2019-03-15 2023-05-02 Ｔｅａｄ転写因子の新規小分子阻害剤

Country Status (12)

Country Link
US (1) US20230113085A1 (ko)
EP (1) EP3937943A4 (ko)
JP (2) JP2022525186A (ko)
KR (1) KR20210143803A (ko)
CN (1) CN113811300B (ko)
AU (1) AU2020241258A1 (ko)
BR (1) BR112021018303A2 (ko)
CA (1) CA3133753A1 (ko)
IL (1) IL286352A (ko)
MA (1) MA55322A (ko)
MX (1) MX2021011209A (ko)
WO (1) WO2020190774A1 (ko)

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US11458149B1 (en) 2019-05-31 2022-10-04 Ikena Oncology, Inc. TEAD inhibitors and uses thereof
US11787775B2 (en) 2020-07-24 2023-10-17 Genentech, Inc. Therapeutic compounds and methods of use
WO2022120355A1 (en) 2020-12-02 2022-06-09 Ikena Oncology, Inc. Tead degraders and uses thereof
WO2022120353A1 (en) * 2020-12-02 2022-06-09 Ikena Oncology, Inc. Tead inhibitors and uses thereof
JP2024505196A (ja) 2021-01-25 2024-02-05 イケナ オンコロジー， インコーポレイテッド 肺癌の処置において使用するためのｔｅａｄ阻害剤３－（イミダゾール－４－イル）－４－（アミノ）－ベンゼンスルホンアミドとｅｇｆｒ阻害剤及び／またはｍｅｋ阻害剤との組み合わせ
CA3215081A1 (en) 2021-04-16 2022-10-20 Alfredo C. Castro Mek inhibitors and uses thereof
WO2023060227A1 (en) 2021-10-07 2023-04-13 Ikena Oncology, Inc. Tead inhibitors and uses thereof
TW202334091A (zh) * 2021-12-23 2023-09-01 比利時魯汶大學 用於抑制ｙａｐ／ｔａｚ－ｔｅａｄ之四氫苯并氮呯酮及相關類似物
WO2023173053A1 (en) 2022-03-10 2023-09-14 Ikena Oncology, Inc. Mek inhibitors and uses thereof
WO2023173057A1 (en) 2022-03-10 2023-09-14 Ikena Oncology, Inc. Mek inhibitors and uses thereof
US11878958B2 (en) 2022-05-25 2024-01-23 Ikena Oncology, Inc. MEK inhibitors and uses thereof
CN115181756B (zh) * 2022-08-03 2023-06-16 四川省医学科学院·四川省人民医院 一种重组慢病毒载体、重组慢病毒质粒、细胞模型及相关应用
TW202423428A (zh) 2022-09-29 2024-06-16 香港商英矽智能科技知識產權有限公司 Tead抑制劑及其使用方法
WO2024092116A1 (en) 2022-10-26 2024-05-02 Ikena Oncology, Inc. Combination of tead inhibitors and egfr inhibitors and uses thereof
CN117986195A (zh) * 2023-01-10 2024-05-07 四川大学 一种新型杂环化合物及其制备方法和用途
CN115850190B (zh) * 2023-01-10 2024-09-10 四川大学 一种5-氟尿嘧啶衍生物及其抗肿瘤用途
WO2024173761A1 (en) 2023-02-17 2024-08-22 Ikena Oncology, Inc. Combinations comprising mek inhibitors for use in the treatment of cancer
CN118146146B (zh) * 2024-05-11 2024-07-05 北京勤邦科技股份有限公司 氟尼辛葡甲胺含量检测用半抗原及其应用

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