|
ATE87659T1
(de)
|
1986-09-02 |
1993-04-15 |
Enzon Lab Inc |
Bindungsmolekuele mit einzelpolypeptidkette.
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
ATE199392T1
(de)
|
1992-12-04 |
2001-03-15 |
Medical Res Council |
Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
PT1355919E
(pt)
|
2000-12-12 |
2011-03-02 |
Medimmune Llc |
Moléculas com semivida longa, composições que as contêm e suas utilizações
|
|
FR2858235B1
(fr)
|
2003-07-31 |
2006-02-17 |
Lab Francais Du Fractionnement |
Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
US7767792B2
(en)
|
2004-02-20 |
2010-08-03 |
Ludwig Institute For Cancer Research Ltd. |
Antibodies to EGF receptor epitope peptides
|
|
CN101501211A
(zh)
|
2004-03-31 |
2009-08-05 |
综合医院公司 |
测定癌症对表皮生长因子受体靶向性治疗反应性的方法
|
|
EP1766068A4
(en)
|
2004-06-04 |
2010-03-03 |
Genentech Inc |
EGFR Mutations
|
|
EP1789446A2
(en)
|
2004-09-02 |
2007-05-30 |
Genentech, Inc. |
Heteromultimeric molecules
|
|
CA2592177A1
(en)
|
2005-01-21 |
2006-07-27 |
Genentech, Inc. |
Fixed dosing of her antibodies
|
|
CN101193905B
(zh)
|
2005-02-11 |
2014-06-25 |
纪念斯隆-凯特林癌症中心 |
用于检测抗药egfr突变体的方法和组合物
|
|
MX2007009963A
(es)
|
2005-02-24 |
2007-09-26 |
Amgen Inc |
Mutaciones del receptor del factor de crecimiento epidermico.
|
|
WO2006104911A2
(en)
|
2005-03-25 |
2006-10-05 |
Genentech, Inc. |
Methods and compositions for modulating hyperstabilized c-met
|
|
EP3050963B1
(en)
|
2005-03-31 |
2019-09-18 |
Chugai Seiyaku Kabushiki Kaisha |
Process for production of polypeptide by regulation of assembly
|
|
DE102005028778A1
(de)
|
2005-06-22 |
2006-12-28 |
SUNJÜT Deutschland GmbH |
Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
|
|
US8871912B2
(en)
|
2006-03-24 |
2014-10-28 |
Merck Patent Gmbh |
Engineered heterodimeric protein domains
|
|
WO2007147901A1
(en)
|
2006-06-22 |
2007-12-27 |
Novo Nordisk A/S |
Production of bispecific antibodies
|
|
US20080226635A1
(en)
|
2006-12-22 |
2008-09-18 |
Hans Koll |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
|
CA2683559C
(en)
|
2007-04-13 |
2019-09-24 |
Dana Farber Cancer Institute, Inc. |
Methods for treating cancer resistant to erbb therapeutics
|
|
KR20100058509A
(ko)
|
2007-07-31 |
2010-06-03 |
메디뮨 엘엘씨 |
다중특이적 에피토프 결합 단백질 및 이의 용도
|
|
US7892770B2
(en)
|
2007-08-24 |
2011-02-22 |
Van Andel Research Institute |
Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods
|
|
JP2011507519A
(ja)
|
2007-12-19 |
2011-03-10 |
セントコア・オーソ・バイオテツク・インコーポレーテツド |
pIX又はpVIIへの融合を介したヒトデノボpIXファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法
|
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
|
ES2563027T3
(es)
|
2008-01-07 |
2016-03-10 |
Amgen Inc. |
Método para fabricación de moléculas heterodímeras Fc de anticuerpos utilizando efectos de conducción electrostática
|
|
EP2260056A1
(en)
*
|
2008-03-06 |
2010-12-15 |
Genentech, Inc. |
Combination therapy with c-met and her antagonists
|
|
JP2012525149A
(ja)
|
2009-04-27 |
2012-10-22 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
ヘテロ多量体分子を作製するための方法
|
|
DK2560993T3
(da)
|
2010-04-20 |
2024-10-14 |
Genmab As |
Heterodimeric antibody fc-containing proteins and methods for production thereof
|
|
US8962808B2
(en)
|
2010-05-05 |
2015-02-24 |
The Research Foundation For The State University Of New York |
EGFR-related polypeptides and methods of use
|
|
PL2635607T3
(pl)
|
2010-11-05 |
2020-05-18 |
Zymeworks Inc. |
Projekt stabilnego przeciwciała heterodimerowego z mutacjami w domenie FC
|
|
US10570211B2
(en)
|
2011-01-24 |
2020-02-25 |
Gilead Sciences, Inc. |
Antibodies selective for cells presenting EGFR at high density
|
|
US9683052B2
(en)
|
2011-03-25 |
2017-06-20 |
Glenmark Pharmaceuticals S.A. |
Hetero-dimeric immunoglobulins
|
|
KR20130036993A
(ko)
|
2011-10-05 |
2013-04-15 |
삼성전자주식회사 |
c-Met의 SEMA 도메인 내의 에피토프에 특이적으로 결합하는 항체
|
|
CN107266577B
(zh)
|
2011-10-11 |
2022-09-13 |
弗·哈夫曼-拉罗切有限公司 |
双特异性抗体的改进的组装
|
|
CA2854233C
(en)
|
2011-11-04 |
2020-05-12 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
|
US20170275367A1
(en)
*
|
2012-11-21 |
2017-09-28 |
Janssen Biotech, Inc. |
Bispecific EGFR/C-Met Antibodies
|
|
CN113201073A
(zh)
*
|
2012-11-21 |
2021-08-03 |
詹森生物科技公司 |
双特异性EGFR/c-Met抗体
|
|
WO2015043614A1
(en)
*
|
2013-09-26 |
2015-04-02 |
Biontech Ag |
Methods and compositions for prediction of therapeutic efficacy of cancer treatments and cancer prognosis
|
|
AU2015229448B2
(en)
*
|
2014-03-11 |
2020-09-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Anti SIRP-alpha antibodies and Bi-specific Macrophage Enhancing antibodies
|
|
WO2015188777A1
(en)
|
2014-06-12 |
2015-12-17 |
Shanghai Fochon Pharmaceutical Co Ltd |
Certain protein kinase inhibitors
|
|
EP3929190B1
(en)
|
2014-10-13 |
2024-12-25 |
Yuhan Corporation |
Compounds and compositions for modulating egfr mutant kinase activities
|
|
CA2967379A1
(en)
|
2014-11-18 |
2016-05-26 |
Janssen Pharmaceutica Nv |
Cd47 antibodies, methods, and uses
|
|
US10507210B2
(en)
*
|
2014-12-03 |
2019-12-17 |
Auckland Uniservices Limited |
Kinase inhibitor prodrug for the treatment of cancer
|
|
US12595297B2
(en)
*
|
2015-05-12 |
2026-04-07 |
In3Bio Ltd. |
Methods and compositions for inhibition of EGF/EGFR pathway in combination with tyrosine kinase inhibitors
|
|
CA3002957A1
(en)
|
2015-10-23 |
2017-04-27 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Binding molecules that inhibit cancer growth
|
|
JP2018535242A
(ja)
|
2015-11-30 |
2018-11-29 |
メディミューン,エルエルシー |
高濃度のタンパク質ベースの治療剤を含有する医薬組成物中の非晶質安定化化合物としてのアミノ酸と糖との最適比
|
|
EP3453392B1
(en)
|
2016-05-17 |
2025-10-22 |
Japanese Foundation For Cancer Research |
Therapeutic agent for lung cancer that has acquired egfr-tki resistance
|
|
US11649291B2
(en)
|
2016-05-24 |
2023-05-16 |
Insmed Incorporated |
Antibodies and methods of making same
|
|
GB201611123D0
(en)
|
2016-06-27 |
2016-08-10 |
Euremab Srl |
Anti met antibodiesand uses thereof
|
|
HUE054571T2
(hu)
|
2016-09-14 |
2021-09-28 |
Merck Patent Gmbh |
Hatékony tumorgátlásra szolgáló C-MET elleni ellenanyagok és ellenanyag-drog konjugátumaik
|
|
MA46852A
(fr)
|
2016-11-17 |
2019-09-25 |
Univ Texas |
Composés à activité antitumorale contre des cellules cancéreuses porteuses de mutations egfr ou her2 exon 20
|
|
WO2018152634A1
(en)
|
2017-02-22 |
2018-08-30 |
University Of Saskatchewan |
Egfr-binding agents and uses thereof
|
|
AR111469A1
(es)
|
2017-04-21 |
2019-07-17 |
Yuhan Corp |
Sal de un compuesto del derivado de aminopiridina, una forma cristalina de la misma, y un proceso para preparar la misma
|
|
CA3110658A1
(en)
|
2018-09-04 |
2020-03-19 |
Rain Therapeutics Inc. |
Compounds, compositions and methods for treating or preventing her-driven cancers
|
|
SG11202108311RA
(en)
|
2019-02-26 |
2021-09-29 |
Janssen Biotech Inc |
Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
|
|
EP3946293A4
(en)
|
2019-03-29 |
2023-05-03 |
Board of Regents, The University of Texas System |
COMPOUNDS WITH ANTITUMORIC ACTIVITIES AGAINST CANCER CELLS WITH EGFR OR HER2 EXON 20 INSERTATIONS
|
|
SG11202111120VA
(en)
|
2019-04-17 |
2021-11-29 |
Univ Texas |
Compounds against cancer bearing tyrosine kinase inhibitor resistant egfr mutations
|
|
EP3955928A4
(en)
|
2019-04-17 |
2023-05-31 |
Board of Regents, The University of Texas System |
COMPOUNDS HAVING ANTITUMORIC ACTIVITY AGAINST CANCER CELLS WITH TYROSINE KINAS INHIBITOR-RESISTANT EGFR MUTATIONS
|
|
US11850248B2
(en)
|
2019-05-14 |
2023-12-26 |
Yuhan Corporation |
Therapies with 3rd generation EGFR tyrosine kinase inhibitors
|
|
WO2020230091A1
(en)
|
2019-05-14 |
2020-11-19 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
|
TW202309094A
(zh)
*
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|