JPWO2022189942A5 - - Google Patents

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Publication number
JPWO2022189942A5
JPWO2022189942A5 JP2023555245A JP2023555245A JPWO2022189942A5 JP WO2022189942 A5 JPWO2022189942 A5 JP WO2022189942A5 JP 2023555245 A JP2023555245 A JP 2023555245A JP 2023555245 A JP2023555245 A JP 2023555245A JP WO2022189942 A5 JPWO2022189942 A5 JP WO2022189942A5
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JP
Japan
Prior art keywords
egfr
cancer
formulation
seq
bispecific anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023555245A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024509920A5 (https=
JP2024509920A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/052009 external-priority patent/WO2022189942A1/en
Publication of JP2024509920A publication Critical patent/JP2024509920A/ja
Publication of JP2024509920A5 publication Critical patent/JP2024509920A5/ja
Publication of JPWO2022189942A5 publication Critical patent/JPWO2022189942A5/ja
Pending legal-status Critical Current

Links

JP2023555245A 2021-03-09 2022-03-07 Egfr活性化変異を欠くがんの治療 Pending JP2024509920A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163158552P 2021-03-09 2021-03-09
US63/158,552 2021-03-09
PCT/IB2022/052009 WO2022189942A1 (en) 2021-03-09 2022-03-07 Treatment of cancers lacking egfr-activating mutations

Publications (3)

Publication Number Publication Date
JP2024509920A JP2024509920A (ja) 2024-03-05
JP2024509920A5 JP2024509920A5 (https=) 2025-03-13
JPWO2022189942A5 true JPWO2022189942A5 (https=) 2025-03-13

Family

ID=80738936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023555245A Pending JP2024509920A (ja) 2021-03-09 2022-03-07 Egfr活性化変異を欠くがんの治療

Country Status (13)

Country Link
US (1) US20220298248A1 (https=)
EP (1) EP4304644A1 (https=)
JP (1) JP2024509920A (https=)
KR (1) KR20230156094A (https=)
CN (1) CN116997358A (https=)
AU (1) AU2022233518A1 (https=)
BR (1) BR112023018278A2 (https=)
CA (1) CA3212669A1 (https=)
CL (2) CL2023002663A1 (https=)
IL (1) IL305700A (https=)
JO (1) JOP20230211A1 (https=)
MX (1) MX2023010633A (https=)
WO (1) WO2022189942A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL300854A (en) 2020-08-25 2023-04-01 Janssen Biotech Inc Treatment of non-small cell lung cancer with EGFR mutations

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE87659T1 (de) 1986-09-02 1993-04-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE199392T1 (de) 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
EP1766068A4 (en) 2004-06-04 2010-03-03 Genentech Inc EGFR Mutations
EP1789446A2 (en) 2004-09-02 2007-05-30 Genentech, Inc. Heteromultimeric molecules
EP3050963B1 (en) 2005-03-31 2019-09-18 Chugai Seiyaku Kabushiki Kaisha Process for production of polypeptide by regulation of assembly
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
US8871912B2 (en) 2006-03-24 2014-10-28 Merck Patent Gmbh Engineered heterodimeric protein domains
WO2007147901A1 (en) 2006-06-22 2007-12-27 Novo Nordisk A/S Production of bispecific antibodies
KR20100058509A (ko) 2007-07-31 2010-06-03 메디뮨 엘엘씨 다중특이적 에피토프 결합 단백질 및 이의 용도
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
JP2012525149A (ja) 2009-04-27 2012-10-22 オンコメッド ファーマシューティカルズ インコーポレイテッド ヘテロ多量体分子を作製するための方法
DK2560993T3 (da) 2010-04-20 2024-10-14 Genmab As Heterodimeric antibody fc-containing proteins and methods for production thereof
PL2635607T3 (pl) 2010-11-05 2020-05-18 Zymeworks Inc. Projekt stabilnego przeciwciała heterodimerowego z mutacjami w domenie FC
CA2854233C (en) 2011-11-04 2020-05-12 Zymeworks Inc. Stable heterodimeric antibody design with mutations in the fc domain
CN113201073A (zh) * 2012-11-21 2021-08-03 詹森生物科技公司 双特异性EGFR/c-Met抗体
EP2977464A4 (en) * 2013-03-19 2016-10-19 Toppan Printing Co Ltd PROCEDURE FOR PREDICTING SENSITIVITY TO EGFR HEMMER
MA46852A (fr) 2016-11-17 2019-09-25 Univ Texas Composés à activité antitumorale contre des cellules cancéreuses porteuses de mutations egfr ou her2 exon 20
SG11202108311RA (en) * 2019-02-26 2021-09-29 Janssen Biotech Inc Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies

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