JPWO2020152132A5 - - Google Patents
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- Publication number
- JPWO2020152132A5 JPWO2020152132A5 JP2021542335A JP2021542335A JPWO2020152132A5 JP WO2020152132 A5 JPWO2020152132 A5 JP WO2020152132A5 JP 2021542335 A JP2021542335 A JP 2021542335A JP 2021542335 A JP2021542335 A JP 2021542335A JP WO2020152132 A5 JPWO2020152132 A5 JP WO2020152132A5
- Authority
- JP
- Japan
- Prior art keywords
- atoms
- nch
- trisubstituted
- unsubstituted
- replaced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004432 carbon atom Chemical group C* 0.000 description 17
- 229910052760 oxygen Inorganic materials 0.000 description 9
- 229910052717 sulfur Inorganic materials 0.000 description 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 6
- 125000000217 alkyl group Chemical group 0.000 description 5
- 125000002950 monocyclic group Chemical group 0.000 description 5
- 125000003118 aryl group Chemical group 0.000 description 3
- 125000005842 heteroatom Chemical group 0.000 description 3
- 125000000623 heterocyclic group Chemical group 0.000 description 3
- 125000000896 monocarboxylic acid group Chemical group 0.000 description 2
- -1 SO2CH3 Chemical group 0.000 description 1
- 229910006074 SO2NH2 Inorganic materials 0.000 description 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000000565 sulfonamide group Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19152961 | 2019-01-22 | ||
| EP19152961.9 | 2019-01-22 | ||
| PCT/EP2020/051347 WO2020152132A1 (en) | 2019-01-22 | 2020-01-21 | Thiazolopyridine derivatives as adenosine receptor antagonists |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022524914A JP2022524914A (ja) | 2022-05-11 |
| JP2022524914A5 JP2022524914A5 (https=) | 2023-01-31 |
| JPWO2020152132A5 true JPWO2020152132A5 (https=) | 2023-01-31 |
| JP7600119B2 JP7600119B2 (ja) | 2024-12-16 |
Family
ID=65199346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542335A Active JP7600119B2 (ja) | 2019-01-22 | 2020-01-21 | アデノシン受容体アンタゴニストとしてのチアゾロピリジン誘導体 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US12344623B2 (https=) |
| EP (1) | EP3914600B1 (https=) |
| JP (1) | JP7600119B2 (https=) |
| KR (1) | KR102891741B1 (https=) |
| CN (1) | CN113939520B (https=) |
| AR (1) | AR117844A1 (https=) |
| AU (1) | AU2020211697B2 (https=) |
| BR (1) | BR112021014406A2 (https=) |
| CA (1) | CA3127284A1 (https=) |
| DK (1) | DK3914600T3 (https=) |
| ES (1) | ES2992081T3 (https=) |
| FI (1) | FI3914600T3 (https=) |
| HR (1) | HRP20241385T1 (https=) |
| HU (1) | HUE068968T2 (https=) |
| IL (1) | IL285024A (https=) |
| LT (1) | LT3914600T (https=) |
| MX (1) | MX2021008510A (https=) |
| PL (1) | PL3914600T3 (https=) |
| PT (1) | PT3914600T (https=) |
| RS (1) | RS66038B1 (https=) |
| SG (1) | SG11202107858WA (https=) |
| SI (1) | SI3914600T1 (https=) |
| WO (1) | WO2020152132A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022258622A1 (en) | 2021-06-07 | 2022-12-15 | Ares Trading S.A. | Combination treatment of cancer |
| CN119173276A (zh) | 2022-04-13 | 2024-12-20 | 吉利德科学公司 | 用于治疗表达Trop-2的癌症的组合疗法 |
| KR20250048043A (ko) | 2022-08-02 | 2025-04-07 | 메르크 파텐트 게엠베하 | (S)-7-옥사-2-아자-스피로[4.5]데칸-2-카르복실산 [7-(3,6-디히드로-2H-피란-4-일)-4-메톡시-티아졸로[4,5-c]피리딘-2-일]-아미드의 신규의 결정질 형태 및 이의 공-결정 형태 |
| CN116217511B (zh) * | 2023-03-22 | 2024-04-19 | 沈阳药科大学 | 一种双靶点化合物及其制备方法和在制备sEH抑制剂与PPARs激动剂中的应用 |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4125828A (en) | 1972-08-04 | 1978-11-14 | Med-El Inc. | Method and apparatus for automated classification and analysis of cells |
| US4207554A (en) | 1972-08-04 | 1980-06-10 | Med-El Inc. | Method and apparatus for automated classification and analysis of cells |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| US6291455B1 (en) | 1996-03-05 | 2001-09-18 | Zeneca Limited | 4-anilinoquinazoline derivatives |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| AU1688599A (en) | 1998-01-05 | 1999-07-26 | Eisai Co. Ltd. | Purine derivatives and adenosine a2 receptor antagonists serving as preventives/remedies for diabetes |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| US6841549B1 (en) | 1999-07-02 | 2005-01-11 | Eisai Co., Ltd. | Condensed imidazole compounds and a therapeutic agent for diabetes mellitus |
| NZ522074A (en) | 2000-05-31 | 2004-06-25 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| AU8181701A (en) * | 2000-06-21 | 2002-01-02 | Hoffmann La Roche | Benzothiazole derivatives |
| IL153484A0 (en) | 2000-07-07 | 2003-07-06 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors |
| CN1255392C (zh) | 2000-07-07 | 2006-05-10 | 安吉奥金尼药品有限公司 | 作为血管生成抑制剂的秋水仙醇衍生物 |
| WO2004089942A2 (en) | 2001-10-02 | 2004-10-21 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| US6734179B2 (en) * | 2001-12-12 | 2004-05-11 | Hoffmann-La Roche Inc. | Benzothiazoles |
| EP1465634B1 (en) | 2001-12-12 | 2014-10-22 | The Government of the United States of America, as represented by the Secretary Department of Health and Human Services | Methods for using adenosine receptor inhibitors to enhance immune response and inflammation |
| EP1618108A2 (en) | 2003-04-09 | 2006-01-25 | Biogen Idec MA Inc. | Triazolo[1,5-a]pyrimidines and pyrazolo[1,5-a]pyrimidines useful as a2a adenosine receptor antagonists |
| JP4444290B2 (ja) | 2003-05-19 | 2010-03-31 | エフ．ホフマン−ラ ロシュ アーゲー | アデノシン受容体リガンドとしてのベンゾチアゾール誘導体 |
| BRPI0414266A (pt) * | 2003-09-19 | 2006-11-07 | Hoffmann La Roche | derivados de tiazolopiridina como ligandos receptores da adenosina |
| US7054288B2 (en) * | 2004-02-13 | 2006-05-30 | Interdigital Technology Corporation | Method and apparatus for providing fast detection of a high speed shared control channel |
| DE102004008908A1 (de) * | 2004-02-24 | 2005-09-08 | Patent-Treuhand-Gesellschaft für elektrische Glühlampen mbH | Ansteuerschaltung für Wandler |
| FR2867354A1 (fr) * | 2004-03-09 | 2005-09-16 | Joseph Vaillant | Ferrure mecanique pour sabot, notamment pour cheval de sport |
| CN1989139B (zh) | 2004-07-22 | 2010-05-12 | 弗·哈夫曼-拉罗切有限公司 | 苯并噻唑衍生物 |
| WO2014101120A1 (en) | 2012-12-28 | 2014-07-03 | Merck Sharp & Dohme Corp. | Heterobicyclo-substituted-7-methoxy-[1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds with a2a antagonist properties |
| US11220492B2 (en) * | 2017-05-17 | 2022-01-11 | Arcus Biosciences, Inc. | Quinazoline-pyrazole derivatives for the treatment of cancer-related disorders |
| RS64035B1 (sr) * | 2017-08-01 | 2023-04-28 | Merck Patent Gmbh | Derivati tiazolopiridina kao antagonisti receptora adenozina |
-
2020
- 2020-01-20 AR ARP200100134A patent/AR117844A1/es unknown
- 2020-01-21 BR BR112021014406A patent/BR112021014406A2/pt unknown
- 2020-01-21 RS RS20241147A patent/RS66038B1/sr unknown
- 2020-01-21 MX MX2021008510A patent/MX2021008510A/es unknown
- 2020-01-21 PL PL20700918.4T patent/PL3914600T3/pl unknown
- 2020-01-21 US US17/424,568 patent/US12344623B2/en active Active
- 2020-01-21 DK DK20700918.4T patent/DK3914600T3/da active
- 2020-01-21 AU AU2020211697A patent/AU2020211697B2/en active Active
- 2020-01-21 JP JP2021542335A patent/JP7600119B2/ja active Active
- 2020-01-21 SI SI202030510T patent/SI3914600T1/sl unknown
- 2020-01-21 ES ES20700918T patent/ES2992081T3/es active Active
- 2020-01-21 CA CA3127284A patent/CA3127284A1/en active Pending
- 2020-01-21 WO PCT/EP2020/051347 patent/WO2020152132A1/en not_active Ceased
- 2020-01-21 PT PT207009184T patent/PT3914600T/pt unknown
- 2020-01-21 HU HUE20700918A patent/HUE068968T2/hu unknown
- 2020-01-21 EP EP20700918.4A patent/EP3914600B1/en active Active
- 2020-01-21 HR HRP20241385TT patent/HRP20241385T1/hr unknown
- 2020-01-21 SG SG11202107858WA patent/SG11202107858WA/en unknown
- 2020-01-21 FI FIEP20700918.4T patent/FI3914600T3/fi active
- 2020-01-21 CN CN202080010474.8A patent/CN113939520B/zh active Active
- 2020-01-21 KR KR1020217026069A patent/KR102891741B1/ko active Active
- 2020-01-21 LT LTEPPCT/EP2020/051347T patent/LT3914600T/lt unknown
-
2021
- 2021-07-21 IL IL285024A patent/IL285024A/en unknown
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