JPWO2020141180A5 - - Google Patents
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- Publication number
- JPWO2020141180A5 JPWO2020141180A5 JP2021538443A JP2021538443A JPWO2020141180A5 JP WO2020141180 A5 JPWO2020141180 A5 JP WO2020141180A5 JP 2021538443 A JP2021538443 A JP 2021538443A JP 2021538443 A JP2021538443 A JP 2021538443A JP WO2020141180 A5 JPWO2020141180 A5 JP WO2020141180A5
- Authority
- JP
- Japan
- Prior art keywords
- water
- liquid nicotine
- nicotine formulation
- solvents
- immiscible
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 21
- 239000007788 liquid Substances 0.000 claims 21
- 229960002715 nicotine Drugs 0.000 claims 21
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 21
- 238000009472 formulation Methods 0.000 claims 20
- 239000000203 mixture Substances 0.000 claims 20
- 239000002904 solvent Substances 0.000 claims 15
- 239000000443 aerosol Substances 0.000 claims 6
- 150000007524 organic acids Chemical class 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 235000005985 organic acids Nutrition 0.000 claims 3
- 238000005192 partition Methods 0.000 claims 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 2
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 claims 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 150000005846 sugar alcohols Polymers 0.000 claims 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims 2
- 239000003021 water soluble solvent Substances 0.000 claims 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims 1
- -1 MIGLYOL® Chemical compound 0.000 claims 1
- 239000005642 Oleic acid Substances 0.000 claims 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims 1
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 claims 1
- 229960000583 acetic acid Drugs 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 claims 1
- 239000001087 glyceryl triacetate Substances 0.000 claims 1
- 235000013773 glyceryl triacetate Nutrition 0.000 claims 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 229960000448 lactic acid Drugs 0.000 claims 1
- 229940040102 levulinic acid Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 229940107700 pyruvic acid Drugs 0.000 claims 1
- 229960002622 triacetin Drugs 0.000 claims 1
- 239000001069 triethyl citrate Substances 0.000 claims 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 claims 1
- 235000013769 triethyl citrate Nutrition 0.000 claims 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024231883A JP2025060944A (ja) | 2018-12-31 | 2024-12-27 | 液体ニコチン製剤 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18215983 | 2018-12-31 | ||
| EP18215969 | 2018-12-31 | ||
| EP18215976.4 | 2018-12-31 | ||
| EP18215969.9 | 2018-12-31 | ||
| EP18215964 | 2018-12-31 | ||
| EP18215964.0 | 2018-12-31 | ||
| EP18215966.5 | 2018-12-31 | ||
| EP18215983.0 | 2018-12-31 | ||
| EP18215966 | 2018-12-31 | ||
| EP18215976 | 2018-12-31 | ||
| PCT/EP2019/087198 WO2020141180A1 (en) | 2018-12-31 | 2019-12-31 | Liquid nicotine formulation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024231883A Division JP2025060944A (ja) | 2018-12-31 | 2024-12-27 | 液体ニコチン製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022516149A JP2022516149A (ja) | 2022-02-24 |
| JPWO2020141180A5 true JPWO2020141180A5 (enrdf_load_html_response) | 2023-01-11 |
Family
ID=69104449
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021531580A Pending JP2022515021A (ja) | 2018-12-31 | 2019-12-31 | 水不混和性溶媒を含む液体ニコチン製剤 |
| JP2021538444A Pending JP2022516896A (ja) | 2018-12-31 | 2019-12-31 | 低粘度液体ニコチン製剤 |
| JP2021538443A Pending JP2022516149A (ja) | 2018-12-31 | 2019-12-31 | 液体ニコチン製剤 |
| JP2021538442A Pending JP2022516895A (ja) | 2018-12-31 | 2019-12-31 | 部分的水溶性の溶媒を含む液体ニコチン製剤 |
| JP2021531581A Active JP7590324B2 (ja) | 2018-12-31 | 2019-12-31 | 液体ニコチン製剤 |
| JP2024231883A Pending JP2025060944A (ja) | 2018-12-31 | 2024-12-27 | 液体ニコチン製剤 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021531580A Pending JP2022515021A (ja) | 2018-12-31 | 2019-12-31 | 水不混和性溶媒を含む液体ニコチン製剤 |
| JP2021538444A Pending JP2022516896A (ja) | 2018-12-31 | 2019-12-31 | 低粘度液体ニコチン製剤 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538442A Pending JP2022516895A (ja) | 2018-12-31 | 2019-12-31 | 部分的水溶性の溶媒を含む液体ニコチン製剤 |
| JP2021531581A Active JP7590324B2 (ja) | 2018-12-31 | 2019-12-31 | 液体ニコチン製剤 |
| JP2024231883A Pending JP2025060944A (ja) | 2018-12-31 | 2024-12-27 | 液体ニコチン製剤 |
Country Status (11)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021010229A2 (pt) | 2018-12-28 | 2021-08-24 | Philip Morris Products S.A. | Formulação de nicotina líquida compreendendo sal de metal de baixa massa molar |
| EP3905897A1 (en) * | 2018-12-31 | 2021-11-10 | Philip Morris Products, S.A. | Liquid nicotine formulation |
| EP4056055A1 (en) * | 2021-03-09 | 2022-09-14 | Avogen Tech SA | Device for volatilisation of an aqueous solution and method thereof |
| GB202110541D0 (en) * | 2021-07-22 | 2021-09-08 | Nicoventures Trading Ltd | Delivery system |
| KR102416605B1 (ko) | 2021-08-17 | 2022-07-05 | 한국과학기술원 | 비트라인 멀티 레벨 전압 센싱 회로 |
| IT202100027086A1 (it) * | 2021-10-21 | 2023-04-21 | Alberto Patarchi | Erogatore portatile per il trattamento o la prevenzione di un’infezione o di una patologia causata da un virus |
| CN113912585B (zh) * | 2021-11-09 | 2023-02-24 | 深圳萨特瓦生物科技有限公司 | 复合尼古丁盐及其制备方法与应用、电子烟油及电子烟 |
| CN116235996A (zh) * | 2021-12-07 | 2023-06-09 | 深圳雾芯科技有限公司 | 电子烟液及包含其的雾化装置 |
| KR20240012197A (ko) * | 2022-07-20 | 2024-01-29 | 주식회사 케이티앤지 | 표면파 아토마이저에 사용하기 위한 액상형 흡입제형, 이를 포함하는 카트리지 및 에어로졸 생성장치 |
| CN117204598A (zh) * | 2023-07-05 | 2023-12-12 | 深圳梵活生命科学股份有限公司 | 一种应用于雾化器可缓解烟瘾的雾化液 |
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| JP2006109784A (ja) | 2004-10-15 | 2006-04-27 | Mitsubishi Gas Chem Co Inc | パクリタキセルの製造方法 |
| WO2007032962A2 (en) | 2005-09-09 | 2007-03-22 | University Of Kentucky | Compositions and methods for intranasal delivery of tricyclic cannabinoids |
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| UA122320C2 (uk) | 2013-07-19 | 2020-10-26 | Олтріа Клайєнт Сервісиз Ллк | Рідка аерозольна композиція для електронного курильного виробу |
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-
2019
- 2019-12-31 EP EP19831769.5A patent/EP3905897A1/en active Pending
- 2019-12-31 JP JP2021531580A patent/JP2022515021A/ja active Pending
- 2019-12-31 JP JP2021538444A patent/JP2022516896A/ja active Pending
- 2019-12-31 KR KR1020217020778A patent/KR20210108394A/ko active Pending
- 2019-12-31 US US17/419,513 patent/US20220079210A1/en not_active Abandoned
- 2019-12-31 US US17/419,442 patent/US20220071270A1/en active Pending
- 2019-12-31 BR BR112021010593-0A patent/BR112021010593A2/pt unknown
- 2019-12-31 CN CN201980079924.6A patent/CN113163846B/zh active Active
- 2019-12-31 JP JP2021538443A patent/JP2022516149A/ja active Pending
- 2019-12-31 UA UAA202102774A patent/UA129019C2/uk unknown
- 2019-12-31 BR BR112021009726-0A patent/BR112021009726A2/pt unknown
- 2019-12-31 PL PL19831772.9T patent/PL3905900T3/pl unknown
- 2019-12-31 JP JP2021538442A patent/JP2022516895A/ja active Pending
- 2019-12-31 UA UAA202101799A patent/UA129122C2/uk unknown
- 2019-12-31 WO PCT/EP2019/087193 patent/WO2020141176A1/en not_active Ceased
- 2019-12-31 US US17/418,928 patent/US20220053817A1/en active Pending
- 2019-12-31 CN CN201980079953.2A patent/CN113163848B/zh active Active
- 2019-12-31 UA UAA202102775A patent/UA129123C2/uk unknown
- 2019-12-31 UA UAA202101822A patent/UA128585C2/uk unknown
- 2019-12-31 BR BR112021010222-1A patent/BR112021010222A2/pt unknown
- 2019-12-31 BR BR112021010614-6A patent/BR112021010614A2/pt unknown
- 2019-12-31 WO PCT/EP2019/087195 patent/WO2020141177A1/en not_active Ceased
- 2019-12-31 MX MX2021007627A patent/MX2021007627A/es unknown
- 2019-12-31 KR KR1020217020911A patent/KR20210109548A/ko active Pending
- 2019-12-31 US US17/419,374 patent/US11992038B2/en active Active
- 2019-12-31 UA UAA202101830A patent/UA129018C2/uk unknown
- 2019-12-31 EP EP19831772.9A patent/EP3905900B1/en active Active
- 2019-12-31 MX MX2021007623A patent/MX2021007623A/es unknown
- 2019-12-31 CN CN201980079569.2A patent/CN113163845B/zh active Active
- 2019-12-31 MX MX2021007624A patent/MX2021007624A/es unknown
- 2019-12-31 MX MX2021007625A patent/MX2021007625A/es unknown
- 2019-12-31 BR BR112021010284-1A patent/BR112021010284A2/pt unknown
- 2019-12-31 WO PCT/EP2019/087202 patent/WO2020141184A1/en not_active Ceased
- 2019-12-31 WO PCT/EP2019/087196 patent/WO2020141178A1/en not_active Ceased
- 2019-12-31 EP EP19831771.1A patent/EP3905899A1/en active Pending
- 2019-12-31 CN CN201980080351.9A patent/CN113242696B/zh active Active
- 2019-12-31 CN CN201980079943.9A patent/CN113163847B/zh active Active
- 2019-12-31 KR KR1020217020193A patent/KR20210108390A/ko active Pending
- 2019-12-31 JP JP2021531581A patent/JP7590324B2/ja active Active
- 2019-12-31 EP EP19831773.7A patent/EP3905901A1/en active Pending
- 2019-12-31 US US17/419,528 patent/US20220079211A1/en active Pending
- 2019-12-31 KR KR1020217019593A patent/KR20210108384A/ko active Pending
- 2019-12-31 ES ES19831770T patent/ES2980261T3/es active Active
- 2019-12-31 ES ES19831772T patent/ES2981302T3/es active Active
- 2019-12-31 WO PCT/EP2019/087198 patent/WO2020141180A1/en not_active Ceased
- 2019-12-31 EP EP19831770.3A patent/EP3905898B1/en active Active
- 2019-12-31 MX MX2021007626A patent/MX2021007626A/es unknown
- 2019-12-31 KR KR1020217021107A patent/KR20210110314A/ko active Pending
- 2019-12-31 PL PL19831770.3T patent/PL3905898T3/pl unknown
-
2024
- 2024-12-27 JP JP2024231883A patent/JP2025060944A/ja active Pending
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