JPWO2020139171A5 - - Google Patents
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- Publication number
- JPWO2020139171A5 JPWO2020139171A5 JP2021537704A JP2021537704A JPWO2020139171A5 JP WO2020139171 A5 JPWO2020139171 A5 JP WO2020139171A5 JP 2021537704 A JP2021537704 A JP 2021537704A JP 2021537704 A JP2021537704 A JP 2021537704A JP WO2020139171 A5 JPWO2020139171 A5 JP WO2020139171A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- pharmaceutical composition
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000010099 disease Diseases 0.000 claims description 23
- 102000004965 antibodies Human genes 0.000 claims description 22
- 108090001123 antibodies Proteins 0.000 claims description 22
- 239000000427 antigen Substances 0.000 claims description 22
- 108091007172 antigens Proteins 0.000 claims description 22
- 102000038129 antigens Human genes 0.000 claims description 22
- 239000008194 pharmaceutical composition Substances 0.000 claims description 16
- 102000005614 monoclonal antibodies Human genes 0.000 claims description 10
- 108010045030 monoclonal antibodies Proteins 0.000 claims description 10
- 102100004245 TRBV9 Human genes 0.000 claims description 9
- 101710012943 TRBV9 Proteins 0.000 claims description 9
- 108091008153 T cell receptors Proteins 0.000 claims description 8
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims description 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 8
- 210000004027 cells Anatomy 0.000 claims description 8
- 108020004707 nucleic acids Proteins 0.000 claims description 8
- 150000007523 nucleic acids Chemical class 0.000 claims description 8
- 206010002556 Ankylosing spondylitis Diseases 0.000 claims description 5
- 206010009839 Coeliac disease Diseases 0.000 claims description 5
- 208000000389 T-Cell Leukemia Diseases 0.000 claims description 5
- 206010042971 T-cell lymphoma Diseases 0.000 claims description 5
- 230000001404 mediated Effects 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- 239000000546 pharmaceutic aid Substances 0.000 claims description 3
- 108020003175 receptors Proteins 0.000 claims description 3
- 102000004851 Immunoglobulin G Human genes 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 239000001963 growth media Substances 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 150000003384 small molecules Chemical class 0.000 claims description 2
- 239000003270 steroid hormone Substances 0.000 claims description 2
- 239000003708 ampul Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2018146029A RU2711871C1 (ru) | 2018-12-25 | 2018-12-25 | Моноклональные антитела, которые специфически связываются с участком бета цепи семейства TRBV-9 Т-клеточного рецептора человека, и способы их применения |
| RU2018146029 | 2018-12-25 | ||
| PCT/RU2019/050257 WO2020139171A1 (fr) | 2018-12-25 | 2019-12-24 | Anticorps monoclonaux qui se lient spécifiquement à trbv-9 de l'humain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022515820A JP2022515820A (ja) | 2022-02-22 |
| JPWO2020139171A5 true JPWO2020139171A5 (fr) | 2023-01-10 |
| JP7507160B2 JP7507160B2 (ja) | 2024-06-27 |
Family
ID=69184146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021537704A Active JP7507160B2 (ja) | 2018-12-25 | 2019-12-24 | ヒトｔｒｂｖ９に特異的に結合するモノクローナル抗体 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US20220056133A1 (fr) |
| EP (1) | EP3904387A4 (fr) |
| JP (1) | JP7507160B2 (fr) |
| KR (1) | KR20210118843A (fr) |
| CN (1) | CN113692412B (fr) |
| AR (1) | AR117735A1 (fr) |
| AU (1) | AU2019416787A1 (fr) |
| BR (1) | BR112021012550A2 (fr) |
| CA (1) | CA3124800A1 (fr) |
| CL (1) | CL2021001704A1 (fr) |
| CO (1) | CO2021008204A2 (fr) |
| CR (1) | CR20210353A (fr) |
| EA (1) | EA202100199A1 (fr) |
| EC (1) | ECSP21046332A (fr) |
| IL (1) | IL284367A (fr) |
| JO (1) | JOP20210168A1 (fr) |
| MA (1) | MA53688B1 (fr) |
| MX (1) | MX2021007718A (fr) |
| PE (1) | PE20211792A1 (fr) |
| PH (1) | PH12021551535A1 (fr) |
| RU (1) | RU2711871C1 (fr) |
| SG (1) | SG11202106974SA (fr) |
| TW (1) | TW202033557A (fr) |
| WO (1) | WO2020139171A1 (fr) |
| ZA (1) | ZA202104356B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE202019005887U1 (de) | 2018-07-03 | 2023-06-14 | Marengo Therapeutics, Inc. | Anti-TCR-Antikörpermoleküle und Verwendungen davon |
| CN116510006A (zh) * | 2022-01-31 | 2023-08-01 | 拜奥卡德联合股份公司 | 抗trbv9抗体的药物组合物及其用途 |
| WO2024039268A1 (fr) * | 2022-08-18 | 2024-02-22 | Акционерное общество "БИОКАД" | Procédé de traitement de maladie induite par des lymphocytes t |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223426A (en) * | 1988-12-15 | 1993-06-29 | T Cell Sciences, Inc. | Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor |
| US5766947A (en) * | 1988-12-14 | 1998-06-16 | Astra Ab | Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor |
| CA2491864C (fr) * | 2001-07-12 | 2012-09-11 | Jefferson Foote | Anticorps super humanises |
| KR20120044941A (ko) * | 2009-06-25 | 2012-05-08 | 프레드 헛친슨 켄서 리서치 센터 | 적응 면역의 측정방법 |
| WO2012008397A1 (fr) * | 2010-07-12 | 2012-01-19 | 第一三共株式会社 | Anticorps anti-epha2 et utilisation de celui-ci |
| US20130273089A1 (en) * | 2011-11-03 | 2013-10-17 | Tolera Therapeutics, Inc. | Antibody and methods for selective inhibition of t-cell responses |
| ES2759503T3 (es) * | 2013-05-02 | 2020-05-11 | Glykos Finland Oy | Conjugados de una glicoproteína o un glicano con una carga útil tóxica |
| EP3202784A1 (fr) * | 2016-02-08 | 2017-08-09 | Polybiocept AB | Séquences de récepteurs de lymphocytes t pour une immunothérapie active |
| CA3022129A1 (fr) * | 2016-06-17 | 2017-12-21 | Medigene Immunotherapies Gmbh | Recepteurs de lymphocytes t et leurs utilisations |
| AU2017356322B2 (en) * | 2016-11-14 | 2023-09-21 | Fred Hutchinson Cancer Center | High affinity merkel cell polyomavirus T antigen-specific TCRs and uses thereof |
| US20200040085A1 (en) * | 2017-02-27 | 2020-02-06 | Chugai Seiyaku Kabushiki Kaisha | Anti-hla-dq2.5/8 antibody and its use for the treatment of celiac disease |
| CN107502671B (zh) * | 2017-10-12 | 2020-05-05 | 中国医学科学院肿瘤医院 | 利用trbv家族成员预测曲妥珠单抗新辅助治疗乳腺癌患者疗效试剂盒及其应用 |
| RU2694412C9 (ru) * | 2017-12-25 | 2019-09-18 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет им. Н.И. Пирогова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России) | Моноклональные антитела и способы их применения |
-
2018
- 2018-12-25 RU RU2018146029A patent/RU2711871C1/ru active
-
2019
- 2019-12-23 AR ARP190103841A patent/AR117735A1/es unknown
- 2019-12-24 BR BR112021012550-7A patent/BR112021012550A2/pt unknown
- 2019-12-24 CN CN201980092914.6A patent/CN113692412B/zh active Active
- 2019-12-24 EA EA202100199A patent/EA202100199A1/ru unknown
- 2019-12-24 CA CA3124800A patent/CA3124800A1/fr active Pending
- 2019-12-24 KR KR1020217023567A patent/KR20210118843A/ko unknown
- 2019-12-24 WO PCT/RU2019/050257 patent/WO2020139171A1/fr unknown
- 2019-12-24 PE PE2021001079A patent/PE20211792A1/es unknown
- 2019-12-24 SG SG11202106974SA patent/SG11202106974SA/en unknown
- 2019-12-24 MA MA53688A patent/MA53688B1/fr unknown
- 2019-12-24 EP EP19904442.1A patent/EP3904387A4/fr active Pending
- 2019-12-24 TW TW108147433A patent/TW202033557A/zh unknown
- 2019-12-24 US US17/417,570 patent/US20220056133A1/en active Pending
- 2019-12-24 AU AU2019416787A patent/AU2019416787A1/en active Pending
- 2019-12-24 MX MX2021007718A patent/MX2021007718A/es unknown
- 2019-12-24 JP JP2021537704A patent/JP7507160B2/ja active Active
- 2019-12-24 JO JOP/2021/0168A patent/JOP20210168A1/ar unknown
- 2019-12-24 CR CR20210353A patent/CR20210353A/es unknown
-
2021
- 2021-06-23 CO CONC2021/0008204A patent/CO2021008204A2/es unknown
- 2021-06-24 ZA ZA2021/04356A patent/ZA202104356B/en unknown
- 2021-06-24 EC ECSENADI202146332A patent/ECSP21046332A/es unknown
- 2021-06-24 IL IL284367A patent/IL284367A/en unknown
- 2021-06-24 CL CL2021001704A patent/CL2021001704A1/es unknown
- 2021-06-25 PH PH12021551535A patent/PH12021551535A1/en unknown
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