JPWO2020079165A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2020079165A5 JPWO2020079165A5 JP2021521145A JP2021521145A JPWO2020079165A5 JP WO2020079165 A5 JPWO2020079165 A5 JP WO2020079165A5 JP 2021521145 A JP2021521145 A JP 2021521145A JP 2021521145 A JP2021521145 A JP 2021521145A JP WO2020079165 A5 JPWO2020079165 A5 JP WO2020079165A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- mol
- deuterium
- group
- structural formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024107578A JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1816998.7 | 2018-10-18 | ||
| GBGB1816998.7A GB201816998D0 (en) | 2018-10-18 | 2018-10-18 | Compounds |
| GB1909695.7 | 2019-07-05 | ||
| GBGB1909695.7A GB201909695D0 (en) | 2019-07-05 | 2019-07-05 | Compounds |
| PCT/EP2019/078250 WO2020079165A1 (en) | 2018-10-18 | 2019-10-17 | Compounds containing deuterium |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107578A Division JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022512736A JP2022512736A (ja) | 2022-02-07 |
| JPWO2020079165A5 true JPWO2020079165A5 (https=) | 2022-10-18 |
| JP2022512736A5 JP2022512736A5 (https=) | 2022-10-18 |
| JP7603199B2 JP7603199B2 (ja) | 2024-12-20 |
Family
ID=68290247
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521145A Active JP7603199B2 (ja) | 2018-10-18 | 2019-10-17 | 重水素を含有する化合物 |
| JP2024107578A Pending JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107578A Pending JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US12152087B2 (https=) |
| EP (1) | EP3866931B1 (https=) |
| JP (2) | JP7603199B2 (https=) |
| KR (1) | KR102848971B1 (https=) |
| CN (1) | CN112930214B (https=) |
| AU (1) | AU2019362389B2 (https=) |
| BR (1) | BR112021007060A2 (https=) |
| CA (1) | CA3116198A1 (https=) |
| DK (1) | DK3866931T3 (https=) |
| ES (1) | ES2942468T3 (https=) |
| FI (1) | FI3866931T3 (https=) |
| HU (1) | HUE061801T2 (https=) |
| IL (1) | IL282231B2 (https=) |
| MA (1) | MA53904A (https=) |
| MX (1) | MX2021004474A (https=) |
| PL (1) | PL3866931T3 (https=) |
| SG (1) | SG11202103726RA (https=) |
| WO (1) | WO2020079165A1 (https=) |
| ZA (1) | ZA202102492B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201905477D0 (en) * | 2019-04-17 | 2019-05-29 | Oncopeptides Ab | Novel formulations |
| EP4347615B1 (en) * | 2021-06-01 | 2025-05-21 | Synthon B.V. | Process for making melflufen or a salt thereof |
| GB202109895D0 (en) | 2021-07-08 | 2021-08-25 | Oncopeptides Ab | Novel treatments |
| GB202109894D0 (en) | 2021-07-08 | 2021-08-25 | Oncopeptides Ab | Novel treatments |
| WO2023281007A1 (en) | 2021-07-08 | 2023-01-12 | Oncopeptides Ab | Melflufen for use in the treatment of multiple myeloma |
| GB202109896D0 (en) | 2021-07-08 | 2021-08-25 | Oncopeptides Ab | Novel treatments |
| GB202204171D0 (en) | 2022-03-24 | 2022-05-11 | Oncopeptides Ab | Novel formulations |
| WO2026057823A1 (en) * | 2024-09-13 | 2026-03-19 | Oncopeptides Ab | Bis-chloroethylamino derivatives for treating leukemia |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002202D0 (sv) | 2000-06-13 | 2000-06-13 | Karolinska Innovations Ab | New peptides |
| WO2010044981A2 (en) | 2008-09-18 | 2010-04-22 | Auspex Pharmaceutical ,Inc. | Benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| CA2801061A1 (en) | 2010-06-01 | 2011-12-08 | Auspex Pharmaceuticals, Inc. | Benzoquinolone inhibitors of vmat2 |
| CA3024230C (en) * | 2011-04-28 | 2022-10-18 | Oncopeptides Ab | Lyophilized preparation of cytotoxic dipeptides |
| CN104684555A (zh) | 2012-09-18 | 2015-06-03 | 奥斯拜客斯制药有限公司 | 囊泡单胺转运体2的氘化苯并喹啉抑制剂的制剂药代动力学 |
| WO2014065751A1 (en) * | 2012-10-26 | 2014-05-01 | Oncopeptides Ab | Lyophilized preparations of melphalan flufenamide |
| EA202091397A1 (ru) | 2013-01-31 | 2020-09-04 | Ауспекс Фармацетикалс, Инк. | Бензохинолоновые ингибиторы vmat2 |
| KR20150115807A (ko) * | 2013-02-05 | 2015-10-14 | 임파 악치엔게젤샤프트 | 위치-특이적 비대칭 중수소 풍부 카테콜아민 유도체 및 상기 화합물을 포함하는 약제 |
| EA201791466A1 (ru) | 2013-12-03 | 2017-11-30 | Оспекс Фармасьютикалз, Инк. | Способы получения соединений бензохинолина |
| CN110229159B (zh) * | 2013-12-18 | 2021-08-24 | 康塞特医药品有限公司 | 卢索替尼的氘代衍生物 |
| HRP20221106T1 (hr) | 2015-03-06 | 2022-11-25 | Auspex Pharmaceuticals, Inc. | Postupci liječenja abnormalnih nevoljnih poremećaja pokreta |
| GB201507903D0 (en) * | 2015-05-08 | 2015-06-24 | Oncopeptides Ab | Process for preparation of nitrogen mustard derivatives |
| GB201521217D0 (en) * | 2015-12-01 | 2016-01-13 | Oncopeptides Ab | Dosage regimens |
-
2019
- 2019-10-17 PL PL19790194.5T patent/PL3866931T3/pl unknown
- 2019-10-17 AU AU2019362389A patent/AU2019362389B2/en active Active
- 2019-10-17 BR BR112021007060-5A patent/BR112021007060A2/pt unknown
- 2019-10-17 WO PCT/EP2019/078250 patent/WO2020079165A1/en not_active Ceased
- 2019-10-17 HU HUE19790194A patent/HUE061801T2/hu unknown
- 2019-10-17 KR KR1020217011490A patent/KR102848971B1/ko active Active
- 2019-10-17 EP EP19790194.5A patent/EP3866931B1/en active Active
- 2019-10-17 JP JP2021521145A patent/JP7603199B2/ja active Active
- 2019-10-17 CA CA3116198A patent/CA3116198A1/en active Pending
- 2019-10-17 MX MX2021004474A patent/MX2021004474A/es unknown
- 2019-10-17 FI FIEP19790194.5T patent/FI3866931T3/fi active
- 2019-10-17 SG SG11202103726RA patent/SG11202103726RA/en unknown
- 2019-10-17 CN CN201980068384.1A patent/CN112930214B/zh active Active
- 2019-10-17 ES ES19790194T patent/ES2942468T3/es active Active
- 2019-10-17 IL IL282231A patent/IL282231B2/en unknown
- 2019-10-17 US US17/286,002 patent/US12152087B2/en active Active
- 2019-10-17 DK DK19790194.5T patent/DK3866931T3/da active
- 2019-10-17 MA MA053904A patent/MA53904A/fr unknown
-
2021
- 2021-04-15 ZA ZA2021/02492A patent/ZA202102492B/en unknown
-
2024
- 2024-07-03 JP JP2024107578A patent/JP2024150488A/ja active Pending
- 2024-10-16 US US18/917,773 patent/US20250115637A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2395500C2 (ru) | 2,4-пиримидиндиамины, применяемые в лечении неопластических болезней, воспалительных и иммунных расстройств | |
| RU2018106914A (ru) | 1,3,4,-оксадизоламидное производное соединение в качестве ингибитора гистондеацетилазы 6 и содержащая его фармацевтическая композиция | |
| JP2005523922A5 (https=) | ||
| CN113784970A (zh) | Erk抑制剂及其应用 | |
| JP2019014758A5 (https=) | ||
| JP2019517487A5 (https=) | ||
| MX2026001061A (es) | Inhibidores de la fosfatidilinositol 3-cinasa (pi3k) | |
| JP2019521988A5 (https=) | ||
| RU2010126056A (ru) | Органические соединения | |
| JP2013510120A5 (https=) | ||
| JP2011505347A5 (https=) | ||
| RU2009102278A (ru) | Модуляторы рецептора s1p для лечения рассеянного склероза | |
| JP2017530983A5 (https=) | ||
| JP2013544276A5 (https=) | ||
| RU2020108488A (ru) | Бета-гидрокси-гетероциклические амины и их применение для лечения гипергликемии | |
| JP2020111571A5 (https=) | ||
| JPWO2020079165A5 (https=) | ||
| JP2018172383A5 (ja) | 魚介類のベコ病の経口投与用治療剤組成物及びそれを用いた魚介類のベコ病の治療方法 | |
| JP2012506908A5 (https=) | ||
| RU2011121354A (ru) | Синтетические миметики иммунной защиты и их применение | |
| RU2015113959A (ru) | Индолины | |
| RU2011100106A (ru) | Замещенные бензимидазолы для лечения нейрофиброматоза | |
| UA72945C2 (uk) | Сполука (варіанти), фармацевтична композиція, спосіб лікування (варіанти) | |
| CN113439080A (zh) | 作为pd-l1免疫调节剂的乙烯基吡啶甲酰胺基化合物 | |
| JP2019516726A5 (https=) |