JPWO2020077087A5 - - Google Patents
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- Publication number
- JPWO2020077087A5 JPWO2020077087A5 JP2021519159A JP2021519159A JPWO2020077087A5 JP WO2020077087 A5 JPWO2020077087 A5 JP WO2020077087A5 JP 2021519159 A JP2021519159 A JP 2021519159A JP 2021519159 A JP2021519159 A JP 2021519159A JP WO2020077087 A5 JPWO2020077087 A5 JP WO2020077087A5
- Authority
- JP
- Japan
- Prior art keywords
- muscle
- implant
- decellularized
- matrix
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000003205 muscle Anatomy 0.000 claims 58
- 238000000034 method Methods 0.000 claims 38
- 239000007943 implant Substances 0.000 claims 22
- 239000011159 matrix material Substances 0.000 claims 15
- 102000003505 Myosin Human genes 0.000 claims 5
- 108060008487 Myosin Proteins 0.000 claims 5
- 102000004142 Trypsin Human genes 0.000 claims 5
- 108090000631 Trypsin Proteins 0.000 claims 5
- 239000000243 solution Substances 0.000 claims 5
- 239000012588 trypsin Substances 0.000 claims 5
- 239000002245 particle Substances 0.000 claims 4
- 230000007547 defect Effects 0.000 claims 3
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical group OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 2
- 210000002027 skeletal muscle Anatomy 0.000 claims 2
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 1
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 1
- 206010028289 Muscle atrophy Diseases 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 229920001213 Polysorbate 20 Polymers 0.000 claims 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 1
- 230000003187 abdominal effect Effects 0.000 claims 1
- 102000005840 alpha-Galactosidase Human genes 0.000 claims 1
- 108010030291 alpha-Galactosidase Proteins 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 229960003964 deoxycholic acid Drugs 0.000 claims 1
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000010894 electron beam technology Methods 0.000 claims 1
- 238000000386 microscopy Methods 0.000 claims 1
- 201000000585 muscular atrophy Diseases 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024087705A JP2024129014A (ja) | 2018-10-11 | 2024-05-30 | 脱細胞化された筋肉マトリクス |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862744204P | 2018-10-11 | 2018-10-11 | |
| US62/744,204 | 2018-10-11 | ||
| US201962854647P | 2019-05-30 | 2019-05-30 | |
| US62/854,647 | 2019-05-30 | ||
| PCT/US2019/055626 WO2020077087A1 (en) | 2018-10-11 | 2019-10-10 | Decellularized muscle matrix |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024087705A Division JP2024129014A (ja) | 2018-10-11 | 2024-05-30 | 脱細胞化された筋肉マトリクス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022504478A JP2022504478A (ja) | 2022-01-13 |
| JP2022504478A5 JP2022504478A5 (https=) | 2023-04-17 |
| JPWO2020077087A5 true JPWO2020077087A5 (https=) | 2023-04-17 |
Family
ID=68542738
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021519159A Pending JP2022504478A (ja) | 2018-10-11 | 2019-10-10 | 脱細胞化された筋肉マトリクス |
| JP2024087705A Pending JP2024129014A (ja) | 2018-10-11 | 2024-05-30 | 脱細胞化された筋肉マトリクス |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024087705A Pending JP2024129014A (ja) | 2018-10-11 | 2024-05-30 | 脱細胞化された筋肉マトリクス |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20200114043A1 (https=) |
| EP (1) | EP3863692A1 (https=) |
| JP (2) | JP2022504478A (https=) |
| KR (1) | KR20210074316A (https=) |
| CN (1) | CN112839687A (https=) |
| AU (2) | AU2019357600A1 (https=) |
| BR (1) | BR112021006803A2 (https=) |
| CA (1) | CA3114237A1 (https=) |
| WO (1) | WO2020077087A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115779150B (zh) * | 2022-11-08 | 2024-05-28 | 江苏臻亿医疗科技有限公司 | 抗钙化动物源性生物材料、制备方法及其在人工心脏瓣膜、生物补片的应用 |
| EP4704932A1 (en) * | 2023-05-05 | 2026-03-11 | Aroa Biosurgery Limited | Tissue graft compositions and uses thereof |
| CN119455119A (zh) * | 2024-10-26 | 2025-02-18 | 百奥派格(重庆)生物科技有限公司 | 一种猪源肌腱脱细胞材料及其制备方法与应用 |
| CN121081746B (zh) * | 2025-08-26 | 2026-03-31 | 深圳市创科美生物科技有限公司 | 一种脱细胞基质的制备方法及其制备的产品 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005009134A1 (en) | 2003-07-21 | 2005-02-03 | Lifecell Corporation | ACELLULAR TISSUE MATRICES MADE FROM GALACTOSE α-1,3-GALACTOSE-DEFICIENT TISSUE |
| US8735054B1 (en) | 2008-01-04 | 2014-05-27 | Lifecell Corporation | Acellular tissue matrix preservation solution |
| CA2845516C (en) * | 2011-08-17 | 2020-03-24 | Wake Forest University Health Sciences | Muscle tissue regeneration using muscle fiber fragments |
| EP3777906A1 (en) * | 2012-07-06 | 2021-02-17 | LifeCell Corporation | Decellularized muscle matrix |
| CN105658250B (zh) * | 2013-05-07 | 2019-02-26 | 一般财团法人化学及血清疗法研究所 | 包含颗粒状脱细胞组织的混合凝胶 |
| US11110201B2 (en) * | 2017-01-30 | 2021-09-07 | Lifecell Corporation | Devices including muscle matrix and methods of production and use |
-
2019
- 2019-10-10 KR KR1020217013510A patent/KR20210074316A/ko not_active Withdrawn
- 2019-10-10 WO PCT/US2019/055626 patent/WO2020077087A1/en not_active Ceased
- 2019-10-10 CN CN201980066972.1A patent/CN112839687A/zh active Pending
- 2019-10-10 US US16/598,597 patent/US20200114043A1/en not_active Abandoned
- 2019-10-10 BR BR112021006803-1A patent/BR112021006803A2/pt not_active Application Discontinuation
- 2019-10-10 AU AU2019357600A patent/AU2019357600A1/en not_active Abandoned
- 2019-10-10 CA CA3114237A patent/CA3114237A1/en active Pending
- 2019-10-10 EP EP19802333.5A patent/EP3863692A1/en active Pending
- 2019-10-10 JP JP2021519159A patent/JP2022504478A/ja active Pending
-
2024
- 2024-02-21 US US18/583,308 patent/US20240390554A1/en active Pending
- 2024-05-30 JP JP2024087705A patent/JP2024129014A/ja active Pending
-
2025
- 2025-10-13 AU AU2025248757A patent/AU2025248757A1/en active Pending
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