|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
US5387484A
(en)
|
1992-07-07 |
1995-02-07 |
International Business Machines Corporation |
Two-sided mask for patterning of materials with electromagnetic radiation
|
|
ATE386131T1
(de)
|
1994-04-13 |
2008-03-15 |
Univ Rockefeller |
Aav-vermittelte überbringung von dna in zellen des nervensystems
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5625048A
(en)
|
1994-11-10 |
1997-04-29 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
|
AU707866B2
(en)
|
1994-12-06 |
1999-07-22 |
Targeted Genetics Corporation |
Packaging cell lines for generation of high titers of recombinant AAV vectors
|
|
US5741657A
(en)
|
1995-03-20 |
1998-04-21 |
The Regents Of The University Of California |
Fluorogenic substrates for β-lactamase and methods of use
|
|
US6281010B1
(en)
|
1995-06-05 |
2001-08-28 |
The Trustees Of The University Of Pennsylvania |
Adenovirus gene therapy vehicle and cell line
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US5688676A
(en)
|
1995-06-07 |
1997-11-18 |
Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
|
US5846528A
(en)
|
1996-01-18 |
1998-12-08 |
Avigen, Inc. |
Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence
|
|
US5962313A
(en)
|
1996-01-18 |
1999-10-05 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
|
|
US5858351A
(en)
|
1996-01-18 |
1999-01-12 |
Avigen, Inc. |
Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
|
|
AU722375B2
(en)
|
1996-09-06 |
2000-08-03 |
Trustees Of The University Of Pennsylvania, The |
Methods using cre-lox for production of recombinant adeno-associated viruses
|
|
KR20000068501A
(ko)
*
|
1996-09-06 |
2000-11-25 |
트러스티스 오브 더 유니버시티 오브 펜실바니아 |
재조합 아데노-관련 바이러스 지정 유전자 요법을 위한 방법
|
|
WO1998011244A2
(fr)
|
1996-09-11 |
1998-03-19 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Vecteur de vaa4 et ses utilisations
|
|
JP2001506133A
(ja)
|
1996-12-18 |
2001-05-15 |
ターゲティッド ジェネティクス コーポレイション |
組換えａａｖベクターの産生における使用のための、ａａｖスプリット−パッケージング遺伝子およびこのような遺伝子を含む細胞株
|
|
WO1998046273A2
(fr)
|
1997-04-17 |
1998-10-22 |
Paola Leone |
Systeme d'administration d'une therapie genique au cerveau
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
EP1124976A1
(fr)
|
1998-10-27 |
2001-08-22 |
Crucell Holland B.V. |
Production amelioree de vecteurs de virus associes aux adenovirus
|
|
JP2002538770A
(ja)
|
1998-11-10 |
2002-11-19 |
ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
ウイルスベクターとその製造及び投与の方法
|
|
US6225113B1
(en)
|
1998-12-04 |
2001-05-01 |
Genvec, Inc. |
Use of trans-activation and cis-activation to modulate the persistence of expression of a transgene in an at least E4-deficient adenovirus
|
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
|
WO2001023001A2
(fr)
|
1999-09-29 |
2001-04-05 |
The Trustees Of The University Of Pennsylvania |
Procedes de modification rapide du peg de vecteurs viraux, compositions servant a ameliorer la transduction de genes, compositions presentant une stabilite physique augmentee, et leurs utilisations
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
CA2409674C
(fr)
|
2000-05-23 |
2010-05-11 |
Neurologix, Inc. |
Systemes de delivrance bases sur l'acide glutamique decarboxylase (gad)
|
|
ATE318923T1
(de)
|
2000-06-01 |
2006-03-15 |
Univ North Carolina |
Doppelsträngige parvovirus-vektoren
|
|
AU2001268373A1
(en)
|
2000-06-13 |
2001-12-24 |
The Children's Hospital Of Philadelphia |
Methods for administering recombinant adeno-associated virus virions to humans previously exposed to adeno-associated virus
|
|
DE60129229T2
(de)
|
2000-08-17 |
2008-05-08 |
Ozawa, Keiya |
Adeno-assoziierte virus-vermittelte übertragung von angiogenesefaktoren
|
|
US7588757B2
(en)
|
2001-03-14 |
2009-09-15 |
Genzyme Corporation |
Methods of treating Parkinson's disease using recombinant adeno-associated virus virions
|
|
DK1310571T3
(da)
|
2001-11-13 |
2006-06-19 |
Univ Pennsylvania |
Fremgangsmåde til identifikation af ukendte adeno-associerede virussekvenser (AAV-sekvenser) og et kit til fremgangsmåden
|
|
EP1463805B1
(fr)
|
2001-12-17 |
2014-10-22 |
The Trustees of The University of Pennsylvania |
Sequences du serotype 9 du virus associe a l'adenovirus (aav), vecteurs les contenant et utilisations correspondantes
|
|
JP2005516949A
(ja)
|
2001-12-19 |
2005-06-09 |
リジュン・ワン |
Ｇｄｎｆの骨格筋へのアデノ随伴ウイルス媒介性のデリバリー
|
|
US8946151B2
(en)
|
2003-02-24 |
2015-02-03 |
Northern Bristol N.H.S. Trust Frenchay Hospital |
Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
|
|
US8927269B2
(en)
|
2003-05-19 |
2015-01-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Avian adenoassociated virus and uses thereof
|
|
JP4888876B2
(ja)
|
2003-06-13 |
2012-02-29 |
田平 武 |
アルツハイマー病の治療のための組換えアデノ随伴ウィルスベクター
|
|
ES2629087T3
(es)
|
2003-06-19 |
2017-08-07 |
Genzyme Corporation |
Viriones de AAV con inmunorreactividad reducida y usos de los mismos
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
ES2411479T3
(es)
|
2003-09-30 |
2013-07-05 |
The Trustees Of The University Of Pennsylvania |
Clados de virus adeno-asociados (AAV), secuencias, vectores que los contienen, y usos de los mismos
|
|
WO2005056807A2
(fr)
|
2003-12-04 |
2005-06-23 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health |
Vecteur viral associe aux adenovirus bovins et leurs utilisations
|
|
US20060166363A1
(en)
|
2004-01-27 |
2006-07-27 |
Sergei Zolotukhin |
Modified baculovirus expression system for production of pseudotyped rAAV vector
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
EP3085389A1
(fr)
|
2005-04-07 |
2016-10-26 |
The Trustees Of The University Of Pennsylvania |
Procédé d'augmentation de la fonction d'un vecteur aav
|
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
|
EP1857552A1
(fr)
|
2006-05-20 |
2007-11-21 |
Cargill Incorporated |
Xylose isomérase thermostable
|
|
DK1945779T3
(da)
|
2005-10-20 |
2013-06-03 |
Uniqure Ip Bv |
Forbedrede AAV vektorer frembragt i insektceller
|
|
EP2007795B1
(fr)
|
2006-03-30 |
2016-11-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Protéines de capsides aav
|
|
KR101589259B1
(ko)
|
2006-06-21 |
2016-02-01 |
유니큐어 아이피 비.브이. |
곤충세포 내 ａａｖ의 생산에 유용한 ａａｖ-ｒｅｐ78의 번역을 위한 변형된 개시 코돈을 갖는 벡터
|
|
EP2158211B1
(fr)
|
2007-05-31 |
2016-08-10 |
Medigene AG |
Protéine structurale mutée d'un parvovirus
|
|
SI2173888T1
(sl)
|
2007-07-26 |
2017-01-31 |
Uniqure Ip B.V. |
Bakulovirusni vektorji, ki vsebujejo ponavljajoča kodirna zaporedja z različnimi kodonskimi preferencami
|
|
WO2010093784A2
(fr)
|
2009-02-11 |
2010-08-19 |
The University Of North Carolina At Chapel Hill |
Vecteurs viraux modifiés et procédés de fabrication et d'utilisation de ceux-ci
|
|
WO2010138263A2
(fr)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Nouveaux virus adéno-associés (aav) et leurs utilisations
|
|
WO2011101869A1
(fr)
|
2010-02-22 |
2011-08-25 |
Transgene Biotek Ltd. |
Traitement contre le cancer du foie impliquant l'adénovirus associé 2/8 et le micro-arn 101
|
|
EP2394667A1
(fr)
|
2010-06-10 |
2011-12-14 |
Laboratorios Del Dr. Esteve, S.A. |
Vecteurs et séquences pour le traitement de maladies
|
|
EP2634253B1
(fr)
|
2010-10-27 |
2016-05-11 |
Jichi Medical University |
Virions de virus adéno-associé pour le transfert de gènes dans des cellules neuronales
|
|
WO2012115980A1
(fr)
|
2011-02-22 |
2012-08-30 |
California Institute Of Technology |
Fourniture de protéines au moyen de vecteurs de virus adéno-associés (aav)
|
|
EP3219313B1
(fr)
|
2011-04-18 |
2020-10-28 |
National Center of Neurology and Psychiatry |
Particule de libération de médicament et son procédé de fabrication
|
|
EP3795581A3
(fr)
|
2011-08-24 |
2021-06-09 |
The Board of Trustees of the Leland Stanford Junior University |
Nouvelles protéines de capside avv pour le transfert d'acides nucléiques
|
|
US20140359799A1
(en)
|
2011-12-23 |
2014-12-04 |
Case Western Reserve University |
Targeted gene modification using hybrid recombinant adeno-associated virus
|
|
US9636370B2
(en)
|
2012-09-28 |
2017-05-02 |
The University Of North Carolina At Chapel Hill |
AAV vectors targeted to oligodendrocytes
|
|
US9567376B2
(en)
|
2013-02-08 |
2017-02-14 |
The Trustees Of The University Of Pennsylvania |
Enhanced AAV-mediated gene transfer for retinal therapies
|
|
IL293294B2
(en)
|
2013-03-15 |
2023-04-01 |
Univ North Carolina Chapel Hill |
Methods and compounds for ligation of paired aav glycan vectors
|
|
CA2911105A1
(fr)
|
2013-05-01 |
2014-11-06 |
Genzyme Corporation |
Compositions et procedes pour traiter l'amyotrophie spinale
|
|
WO2014194132A1
(fr)
|
2013-05-31 |
2014-12-04 |
The Regents Of The University Of California |
Variants de virus adéno-associés et leurs méthodes d'utilisation
|
|
EP3044318B1
(fr)
|
2013-09-13 |
2019-05-01 |
California Institute of Technology |
Récupération sélective
|
|
JP6985795B2
(ja)
|
2013-09-26 |
2021-12-22 |
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド |
標的遺伝子治療のための合成コンビナトリアルａａｖカプシドライブラリー
|
|
US10087224B2
(en)
|
2013-11-01 |
2018-10-02 |
Cornell University |
Gene therapy for Alzheimer's and other neurodegenerative diseases and conditions
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
PE20170260A1
(es)
|
2014-05-02 |
2017-04-12 |
Genzyme Corp |
Vectores de aav para la terapia genica de la retina y el snc
|
|
WO2015191508A1
(fr)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Capsides chimériques
|
|
CN106662401A
(zh)
|
2014-07-07 |
2017-05-10 |
株式会社Ihi |
热处理装置
|
|
BR112017005892A2
(pt)
|
2014-09-24 |
2017-12-12 |
Hope City |
variantes de vetor de vírus adeno-associado para edição de genoma de alta eficácia e métodos da mesma
|
|
AU2015335923B2
(en)
|
2014-10-21 |
2021-04-29 |
University Of Massachusetts |
Recombinant AAV variants and uses thereof
|
|
CA2970730A1
(fr)
*
|
2015-01-16 |
2016-07-21 |
Voyager Therapeutics, Inc. |
Polynucleotides de ciblage du systeme nerveux central
|
|
BR112017017867A2
(pt)
|
2015-02-20 |
2018-04-10 |
Fond Telethon |
métodos e composições para tratamento de doenças oculares genéticas
|
|
JP2018509164A
(ja)
*
|
2015-03-10 |
2018-04-05 |
ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク |
組換えＧｌｕｔ１アデノ随伴ウイルスベクターコンストラクトおよびＧｌｕｔ１発現を回復させる方法
|
|
WO2016150964A1
(fr)
*
|
2015-03-23 |
2016-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Procédés et composition pharmaceutique pour le traitement et la prévention du phénotype neurologique associé à l'ataxie de friedreich
|
|
WO2017015102A1
(fr)
|
2015-07-17 |
2017-01-26 |
The Trustees Of The University Of Pennsylvania |
Compositions et procédés pour obtenir des niveaux élevés de transduction dans des cellules hépatiques humaines
|
|
IL257628B2
(en)
|
2015-09-28 |
2023-04-01 |
Univ North Carolina Chapel Hill |
Methods and compositions for stealth virus antibody vectors
|
|
WO2017066764A2
(fr)
|
2015-10-16 |
2017-04-20 |
William Marsh Rice University |
Modification de la région n-terminale des protéines de capsides pour améliorer les propriétés des virus adéno-associés
|
|
CA3002406A1
(fr)
*
|
2015-10-29 |
2017-05-04 |
Voyager Therapeutics, Inc. |
Distribution de polynucleotides de ciblage du systeme nerveux central
|
|
KR102200642B1
(ko)
*
|
2015-11-05 |
2021-01-12 |
뱀부 테라퓨틱스 인코포레이티드 |
유전자 치료를 위한 변형된 프리드라이히 운동실조증 유전자 및 벡터
|
|
EP3374494A4
(fr)
|
2015-11-11 |
2019-05-01 |
Coda Biotherapeutics, Inc. |
Compositions crispr et leurs méthodes d'utilisation pour la thérapie génique
|
|
US10240145B2
(en)
|
2015-11-25 |
2019-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
CRISPR/Cas-mediated genome editing to treat EGFR-mutant lung cancer
|
|
ES2869284T3
(es)
|
2015-12-11 |
2021-10-25 |
California Inst Of Techn |
Péptidos de diana para dirigir virus adenoasociados (AAV)
|
|
CN110139933B
(zh)
*
|
2016-11-09 |
2024-03-08 |
英特瑞克斯顿股份有限公司 |
共济蛋白表达构建体
|
|
WO2019079240A1
(fr)
*
|
2017-10-16 |
2019-04-25 |
Voyager Therapeutics, Inc. |
Traitement de la sclérose latérale amyotrophique (sla)
|