|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
US5387484A
(en)
|
1992-07-07 |
1995-02-07 |
International Business Machines Corporation |
Two-sided mask for patterning of materials with electromagnetic radiation
|
|
WO1995028493A1
(fr)
|
1994-04-13 |
1995-10-26 |
The Rockefeller University |
Transmission par virus adenoassocie d'adn a des cellules du systeme nerveux
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5625048A
(en)
|
1994-11-10 |
1997-04-29 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
|
EP0796339A1
(fr)
|
1994-12-06 |
1997-09-24 |
Targeted Genetics Corporation |
Lignees cellulaires d'encapsidation utilisees pour la generation de titres hauts de vecteurs aav recombinants
|
|
US5741657A
(en)
|
1995-03-20 |
1998-04-21 |
The Regents Of The University Of California |
Fluorogenic substrates for β-lactamase and methods of use
|
|
US6281010B1
(en)
|
1995-06-05 |
2001-08-28 |
The Trustees Of The University Of Pennsylvania |
Adenovirus gene therapy vehicle and cell line
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US5688676A
(en)
|
1995-06-07 |
1997-11-18 |
Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
|
US5858351A
(en)
|
1996-01-18 |
1999-01-12 |
Avigen, Inc. |
Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
|
|
US5846528A
(en)
|
1996-01-18 |
1998-12-08 |
Avigen, Inc. |
Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence
|
|
US5962313A
(en)
|
1996-01-18 |
1999-10-05 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
|
|
KR20000068501A
(ko)
*
|
1996-09-06 |
2000-11-25 |
트러스티스 오브 더 유니버시티 오브 펜실바니아 |
재조합 아데노-관련 바이러스 지정 유전자 요법을 위한 방법
|
|
WO1998010086A1
(fr)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Procede d'utilisation de cre-lox pour la production de virus adeno-associes de recombinaison
|
|
CA2265460A1
(fr)
|
1996-09-11 |
1998-03-19 |
The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services |
Vecteur de vaa4 et ses utilisations
|
|
CA2270285A1
(fr)
|
1996-12-18 |
1998-06-25 |
Targeted Genetics Corporation |
Genes d'encapsidation fractionnes de virus adeno-associe (aav) et lignees cellulaires comprenant ces genes utilises pour la production de vecteurs d'aav de recombinaison
|
|
WO1998046273A2
(fr)
|
1997-04-17 |
1998-10-22 |
Paola Leone |
Systeme d'administration d'une therapie genique au cerveau
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
MXPA01004169A
(es)
|
1998-10-27 |
2002-06-04 |
Crucell Holland Bv |
Produccion mejorada de vector de virus adenoasociados.
|
|
JP2002538770A
(ja)
|
1998-11-10 |
2002-11-19 |
ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
ウイルスベクターとその製造及び投与の方法
|
|
US6225113B1
(en)
|
1998-12-04 |
2001-05-01 |
Genvec, Inc. |
Use of trans-activation and cis-activation to modulate the persistence of expression of a transgene in an at least E4-deficient adenovirus
|
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
|
US6399385B1
(en)
|
1999-09-29 |
2002-06-04 |
The Trustees Of The University Of Pennsylvania |
Methods for rapid PEG-modification of viral vectors, compositions for enhanced gene transduction, compositions with enhanced physical stability, and uses therefor
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
AU6808001A
(en)
|
2000-05-23 |
2001-12-03 |
Neurologix Inc |
Glutamic acid decarboxylase (gad) based delivery systems
|
|
AU2001269723B9
(en)
|
2000-06-01 |
2006-11-16 |
University Of North Carolina At Chapel Hill |
Duplexed parvovirus vectors
|
|
US20020106381A1
(en)
|
2000-06-13 |
2002-08-08 |
High Katherine A. |
Methods for administering recombinant adeno-associated virus virions to humans previously exposed to adeno-associated virus
|
|
AU2001294096A1
(en)
|
2000-08-17 |
2002-02-25 |
Uichi Ikeda |
Adeno-associated virus-mediated delivery of angiogenic factors
|
|
US7588757B2
(en)
|
2001-03-14 |
2009-09-15 |
Genzyme Corporation |
Methods of treating Parkinson's disease using recombinant adeno-associated virus virions
|
|
EP2338900B1
(fr)
|
2001-11-13 |
2014-01-01 |
The Trustees of The University of Pennsylvania |
Séquences de virus adéno-associé (AAV) Cy.5, vecteurs comprenant lesdites et leurs utilisations
|
|
AU2002359284A1
(en)
|
2001-12-17 |
2003-06-30 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
|
|
JP2005516949A
(ja)
|
2001-12-19 |
2005-06-09 |
リジュン・ワン |
Ｇｄｎｆの骨格筋へのアデノ随伴ウイルス媒介性のデリバリー
|
|
US8946151B2
(en)
|
2003-02-24 |
2015-02-03 |
Northern Bristol N.H.S. Trust Frenchay Hospital |
Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
|
|
WO2005017101A2
(fr)
|
2003-05-19 |
2005-02-24 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH |
Virus aviaire adenoassocie (aaav) et ses utilisations
|
|
JP4888876B2
(ja)
|
2003-06-13 |
2012-02-29 |
田平 武 |
アルツハイマー病の治療のための組換えアデノ随伴ウィルスベクター
|
|
PT2657247T
(pt)
|
2003-06-19 |
2017-06-29 |
Genzyme Corp |
Viriões aav com imunorreatividade diminuída e seus usos
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
CN102199626B
(zh)
|
2003-09-30 |
2015-06-24 |
宾夕法尼亚大学托管会 |
腺伴随病毒(aav)进化支、序列、含有这些序列的载体及它们的应用
|
|
WO2005056807A2
(fr)
|
2003-12-04 |
2005-06-23 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health |
Vecteur viral associe aux adenovirus bovins et leurs utilisations
|
|
WO2005072364A2
(fr)
|
2004-01-27 |
2005-08-11 |
University Of Florida |
Systeme d'expression baculovirus modifie utilise pour la production d'un vecteur raav pseudotype
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
CN101203613B
(zh)
|
2005-04-07 |
2012-12-12 |
宾夕法尼亚大学托管会 |
增强腺相关病毒载体功能的方法
|
|
WO2006119432A2
(fr)
|
2005-04-29 |
2006-11-09 |
The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services |
Isolation, clonage, et caracterisation de nouveaux serotypes de virus adeno-associes (avv)
|
|
EP1857552A1
(fr)
|
2006-05-20 |
2007-11-21 |
Cargill Incorporated |
Xylose isomérase thermostable
|
|
AU2006304997B2
(en)
|
2005-10-20 |
2012-03-01 |
Uniqure Ip B.V. |
Improved AAV vectors produced in insect cells
|
|
WO2007120542A2
(fr)
|
2006-03-30 |
2007-10-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bibliothèque de capsides aav et protéines de capsides aav
|
|
CN101506369B
(zh)
|
2006-06-21 |
2014-02-12 |
尤尼克尔生物制药股份有限公司 |
具有经修饰的用于在昆虫细胞中产生aav的aav-rep78翻译起始密码子的载体
|
|
EP2158211B1
(fr)
|
2007-05-31 |
2016-08-10 |
Medigene AG |
Protéine structurale mutée d'un parvovirus
|
|
AU2008279883B2
(en)
|
2007-07-26 |
2013-12-05 |
Uniqure Ip B.V. |
Baculoviral vectors comprising repeated coding sequences with differential codon biases
|
|
US8889641B2
(en)
|
2009-02-11 |
2014-11-18 |
The University Of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
WO2010138263A2
(fr)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Nouveaux virus adéno-associés (aav) et leurs utilisations
|
|
WO2011101869A1
(fr)
|
2010-02-22 |
2011-08-25 |
Transgene Biotek Ltd. |
Traitement contre le cancer du foie impliquant l'adénovirus associé 2/8 et le micro-arn 101
|
|
EP2394667A1
(fr)
|
2010-06-10 |
2011-12-14 |
Laboratorios Del Dr. Esteve, S.A. |
Vecteurs et séquences pour le traitement de maladies
|
|
CN107828820B
(zh)
|
2010-10-27 |
2022-06-07 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
|
JP6091435B2
(ja)
|
2011-02-22 |
2017-03-08 |
カリフォルニア インスティチュート オブ テクノロジー |
アデノ随伴ウイルス（ａａｖ）ベクターを用いたタンパク質の送達
|
|
US9610354B2
(en)
|
2011-04-18 |
2017-04-04 |
National Center Of Neurology And Psychiatry |
Drug delivery particle and method for producing the same
|
|
US9169299B2
(en)
|
2011-08-24 |
2015-10-27 |
The Board Of Trustees Of The Leleand Stanford Junior University |
AAV capsid proteins for nucleic acid transfer
|
|
US20140359799A1
(en)
|
2011-12-23 |
2014-12-04 |
Case Western Reserve University |
Targeted gene modification using hybrid recombinant adeno-associated virus
|
|
JP6387350B2
(ja)
|
2012-09-28 |
2018-09-05 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
希突起神経膠細胞を標的とするアデノ随伴ウイルスベクター
|
|
US9567376B2
(en)
|
2013-02-08 |
2017-02-14 |
The Trustees Of The University Of Pennsylvania |
Enhanced AAV-mediated gene transfer for retinal therapies
|
|
IL298049B2
(en)
|
2013-03-15 |
2023-10-01 |
Univ North Carolina Chapel Hill |
Methods and compounds for ligation of paired AAV glycan vectors
|
|
WO2014178863A1
(fr)
|
2013-05-01 |
2014-11-06 |
Genzyme Corporation |
Compositions et procédés pour traiter l'amyotrophie spinale
|
|
ES2897508T3
(es)
|
2013-05-31 |
2022-03-01 |
Univ California |
Variantes de virus adenoasociados y métodos de uso de las mismas
|
|
EP3561062A1
(fr)
|
2013-09-13 |
2019-10-30 |
California Institute of Technology |
Récupération sélective
|
|
CA2930549A1
(fr)
|
2013-09-26 |
2015-04-02 |
University Of Florida Research Foundation, Inc. |
Bibliotheque de capsides aav combinatoire synthetique pour la therapie genique ciblee
|
|
US10087224B2
(en)
|
2013-11-01 |
2018-10-02 |
Cornell University |
Gene therapy for Alzheimer's and other neurodegenerative diseases and conditions
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
AU2015252797C1
(en)
|
2014-05-02 |
2021-04-22 |
Genzyme Corporation |
AAV vectors for retinal and CNS gene therapy
|
|
WO2015191508A1
(fr)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Capsides chimériques
|
|
JP6435541B2
(ja)
|
2014-07-07 |
2018-12-12 |
株式会社Ihi |
熱処理装置
|
|
EP3198018B1
(fr)
|
2014-09-24 |
2020-12-09 |
City of Hope |
Variantes des vecteurs de virus associé aux adénovirus de haute efficacité d'édition du génome et des méthodes de celle-ci
|
|
BR112017007737A2
(pt)
|
2014-10-21 |
2018-01-30 |
Univ Massachusetts |
variantes de aav recombinantes e usos das mesmas
|
|
AU2016206478A1
(en)
*
|
2015-01-16 |
2017-06-15 |
Voyager Therapeutics, Inc. |
Central nervous system targeting polynucleotides
|
|
WO2016134375A1
(fr)
|
2015-02-20 |
2016-08-25 |
University Of Iowa Research Foundation |
Méthodes et compositions de traitement de maladies oculaires génétiques
|
|
EA036051B1
(ru)
*
|
2015-03-10 |
2020-09-18 |
Зе Трастис Оф Коламбия Юниверсити Ин Зе Сити Оф Нью-Йорк |
РЕКОМБИНАНТНЫЙ АДЕНОАССОЦИИРОВАННЫЙ ВЕКТОР (rAAV), СПОСОБНЫЙ ПРОНИКАТЬ СКВОЗЬ ГЕМАТОЭНЦЕФАЛИЧЕСКИЙ БАРЬЕР (ГЭБ), И ЕГО ПРИМЕНЕНИЕ ДЛЯ ВОССТАНОВЛЕНИЯ ЭКСПРЕССИИ Glut1
|
|
US11040113B2
(en)
*
|
2015-03-23 |
2021-06-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment and the prevention of neurological phenotype associated with Friedreich ataxia
|
|
US20180216133A1
(en)
|
2015-07-17 |
2018-08-02 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for achieving high levels of transduction in human liver cells
|
|
CN108137655B
(zh)
|
2015-09-28 |
2022-04-22 |
北卡罗来纳-查佩尔山大学 |
逃避抗体的病毒载体的方法和组合物
|
|
WO2017066764A2
(fr)
|
2015-10-16 |
2017-04-20 |
William Marsh Rice University |
Modification de la région n-terminale des protéines de capsides pour améliorer les propriétés des virus adéno-associés
|
|
CA3002406A1
(fr)
*
|
2015-10-29 |
2017-05-04 |
Voyager Therapeutics, Inc. |
Distribution de polynucleotides de ciblage du systeme nerveux central
|
|
PE20181156A1
(es)
*
|
2015-11-05 |
2018-07-19 |
Bamboo Therapeutics Inc |
Genes de ataxia de friedreich modificados y vectores para terapia genica
|
|
EP3374494A4
(fr)
|
2015-11-11 |
2019-05-01 |
Coda Biotherapeutics, Inc. |
Compositions crispr et leurs méthodes d'utilisation pour la thérapie génique
|
|
US10240145B2
(en)
|
2015-11-25 |
2019-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
CRISPR/Cas-mediated genome editing to treat EGFR-mutant lung cancer
|
|
BR112018011711A2
(pt)
|
2015-12-11 |
2018-12-04 |
California Inst Of Techn |
peptídeos de direcionamento para direcionar virus adeno-associados (aav)
|
|
NZ752941A
(en)
*
|
2016-11-09 |
2023-04-28 |
Intrexon Corp |
Frataxin expression constructs
|
|
US11434502B2
(en)
*
|
2017-10-16 |
2022-09-06 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (ALS)
|