JPWO2020053377A5 - - Google Patents
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- Publication number
- JPWO2020053377A5 JPWO2020053377A5 JP2021514324A JP2021514324A JPWO2020053377A5 JP WO2020053377 A5 JPWO2020053377 A5 JP WO2020053377A5 JP 2021514324 A JP2021514324 A JP 2021514324A JP 2021514324 A JP2021514324 A JP 2021514324A JP WO2020053377 A5 JPWO2020053377 A5 JP WO2020053377A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pruritus
- neuropathic pain
- skin disease
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 11
- 208000003251 Pruritus Diseases 0.000 claims 6
- 208000004296 neuralgia Diseases 0.000 claims 4
- 208000021722 neuropathic pain Diseases 0.000 claims 4
- 208000017520 skin disease Diseases 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 208000004454 Hyperalgesia Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010053552 allodynia Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18194297.0 | 2018-09-13 | ||
| EP18194297 | 2018-09-13 | ||
| PCT/EP2019/074465 WO2020053377A1 (en) | 2018-09-13 | 2019-09-13 | A gabaa receptor ligand |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022500445A JP2022500445A (ja) | 2022-01-04 |
| JPWO2020053377A5 true JPWO2020053377A5 (https=) | 2022-10-17 |
| JP2022500445A5 JP2022500445A5 (https=) | 2022-10-17 |
| JP7353663B2 JP7353663B2 (ja) | 2023-10-02 |
Family
ID=63579205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021514324A Active JP7353663B2 (ja) | 2018-09-13 | 2019-09-13 | Ｇａｂａａ受容体リガンド |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US11396510B2 (https=) |
| EP (1) | EP3849976B1 (https=) |
| JP (1) | JP7353663B2 (https=) |
| KR (1) | KR102712565B1 (https=) |
| CN (1) | CN112714765B (https=) |
| AU (1) | AU2019338236B2 (https=) |
| BR (1) | BR112021004661A2 (https=) |
| CA (1) | CA3110283A1 (https=) |
| DK (1) | DK3849976T3 (https=) |
| EA (1) | EA202190717A1 (https=) |
| ES (1) | ES2935705T3 (https=) |
| FI (1) | FI3849976T3 (https=) |
| HR (1) | HRP20230067T1 (https=) |
| HU (1) | HUE060943T2 (https=) |
| IL (1) | IL281335B2 (https=) |
| LT (1) | LT3849976T (https=) |
| MX (1) | MX2021003010A (https=) |
| PH (1) | PH12021550299A1 (https=) |
| PL (1) | PL3849976T3 (https=) |
| PT (1) | PT3849976T (https=) |
| SG (1) | SG11202101360VA (https=) |
| SI (1) | SI3849976T1 (https=) |
| WO (1) | WO2020053377A1 (https=) |
| ZA (1) | ZA202100976B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4322955A1 (en) | 2021-04-16 | 2024-02-21 | Saniona A/S | A gaba receptor modulator for use in the treatment of pain |
| WO2025056751A1 (en) * | 2023-09-15 | 2025-03-20 | Saniona A/S | A gaba receptor modulator for use in the treatment of absence seizures |
| CN121793969A (zh) * | 2023-09-15 | 2026-04-03 | 萨尼奥纳有限责任公司 | 一种用于治疗与睡眠纺锤波缺陷相关的疾病的gaba受体调节剂 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU675484B2 (en) | 1993-03-24 | 1997-02-06 | Neurosearch A/S | Benzimidazole compounds, their use and preparation |
| GB9702524D0 (en) | 1997-02-07 | 1997-03-26 | Merck Sharp & Dohme | Therapeutic agents |
| GB9813576D0 (en) | 1998-06-24 | 1998-08-19 | Merck Sharp & Dohme | Therapeutic agents |
| JP2002535407A (ja) | 1999-01-27 | 2002-10-22 | メルク シャープ エンド ドーム リミテッド | Ｇａｂａ受容体のリガンドとしてのトリアゾロピリダジン誘導体 |
| GB9921150D0 (en) | 1999-09-07 | 1999-11-10 | Merck Sharp & Dohme | Therapeutic agents |
| GB0208394D0 (en) | 2002-04-11 | 2002-05-22 | Merck Sharp & Dohme | Therapeutic agents |
| GB0208392D0 (en) | 2002-04-11 | 2002-05-22 | Merck Sharp & Dohme | Therapeutic compounds |
| GB0212048D0 (en) | 2002-05-24 | 2002-07-03 | Merck Sharp & Dohme | Therapeutic agents |
| WO2004087690A2 (en) | 2003-04-03 | 2004-10-14 | Neurosearch A/S | Benzimidazole derivatives and their use for modulating the gaba-a receptor complex |
| TWI391381B (zh) | 2006-03-24 | 2013-04-01 | Neurosearch As | 新穎的苯并咪唑衍生物、含有其之醫藥組成物、及其於製造藥物之用途 |
| TW201029986A (en) | 2008-11-14 | 2010-08-16 | Neurosearch As | Novel compounds |
| SG11201806393QA (en) | 2016-01-27 | 2018-08-30 | Univ Zuerich | Use of gabaa receptor modulators for treatment of itch |
-
2019
- 2019-09-13 KR KR1020217006185A patent/KR102712565B1/ko active Active
- 2019-09-13 IL IL281335A patent/IL281335B2/en unknown
- 2019-09-13 BR BR112021004661-5A patent/BR112021004661A2/pt unknown
- 2019-09-13 AU AU2019338236A patent/AU2019338236B2/en active Active
- 2019-09-13 SI SI201930443T patent/SI3849976T1/sl unknown
- 2019-09-13 EP EP19765747.1A patent/EP3849976B1/en active Active
- 2019-09-13 JP JP2021514324A patent/JP7353663B2/ja active Active
- 2019-09-13 PT PT197657471T patent/PT3849976T/pt unknown
- 2019-09-13 US US17/272,971 patent/US11396510B2/en active Active
- 2019-09-13 CA CA3110283A patent/CA3110283A1/en active Pending
- 2019-09-13 WO PCT/EP2019/074465 patent/WO2020053377A1/en not_active Ceased
- 2019-09-13 HR HRP20230067TT patent/HRP20230067T1/hr unknown
- 2019-09-13 LT LTEPPCT/EP2019/074465T patent/LT3849976T/lt unknown
- 2019-09-13 CN CN201980059446.2A patent/CN112714765B/zh active Active
- 2019-09-13 SG SG11202101360VA patent/SG11202101360VA/en unknown
- 2019-09-13 HU HUE19765747A patent/HUE060943T2/hu unknown
- 2019-09-13 DK DK19765747.1T patent/DK3849976T3/da active
- 2019-09-13 PL PL19765747.1T patent/PL3849976T3/pl unknown
- 2019-09-13 MX MX2021003010A patent/MX2021003010A/es unknown
- 2019-09-13 EA EA202190717A patent/EA202190717A1/ru unknown
- 2019-09-13 ES ES19765747T patent/ES2935705T3/es active Active
- 2019-09-13 FI FIEP19765747.1T patent/FI3849976T3/fi active
-
2021
- 2021-02-10 PH PH12021550299A patent/PH12021550299A1/en unknown
- 2021-02-12 ZA ZA2021/00976A patent/ZA202100976B/en unknown