PL3849976T3 - Ligand receptora gaba a - Google Patents

Ligand receptora gaba a

Info

Publication number
PL3849976T3
PL3849976T3 PL19765747.1T PL19765747T PL3849976T3 PL 3849976 T3 PL3849976 T3 PL 3849976T3 PL 19765747 T PL19765747 T PL 19765747T PL 3849976 T3 PL3849976 T3 PL 3849976T3
Authority
PL
Poland
Prior art keywords
gaba
receptor ligand
ligand
receptor
Prior art date
Application number
PL19765747.1T
Other languages
English (en)
Inventor
Janus S. Larsen
Dipak AMRUTKAR
Thomas Amos JACOBSEN
Tino Dyhring
Karin Sandager Nielsen
Original Assignee
Saniona A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saniona A/S filed Critical Saniona A/S
Publication of PL3849976T3 publication Critical patent/PL3849976T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL19765747.1T 2018-09-13 2019-09-13 Ligand receptora gaba a PL3849976T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18194297 2018-09-13
PCT/EP2019/074465 WO2020053377A1 (en) 2018-09-13 2019-09-13 A gabaa receptor ligand

Publications (1)

Publication Number Publication Date
PL3849976T3 true PL3849976T3 (pl) 2023-02-27

Family

ID=63579205

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19765747.1T PL3849976T3 (pl) 2018-09-13 2019-09-13 Ligand receptora gaba a

Country Status (24)

Country Link
US (1) US11396510B2 (pl)
EP (1) EP3849976B1 (pl)
JP (1) JP7353663B2 (pl)
KR (1) KR20210061338A (pl)
CN (1) CN112714765B (pl)
AU (1) AU2019338236A1 (pl)
BR (1) BR112021004661A2 (pl)
CA (1) CA3110283A1 (pl)
DK (1) DK3849976T3 (pl)
EA (1) EA202190717A1 (pl)
ES (1) ES2935705T3 (pl)
FI (1) FI3849976T3 (pl)
HR (1) HRP20230067T1 (pl)
HU (1) HUE060943T2 (pl)
IL (1) IL281335B1 (pl)
LT (1) LT3849976T (pl)
MX (1) MX2021003010A (pl)
PH (1) PH12021550299A1 (pl)
PL (1) PL3849976T3 (pl)
PT (1) PT3849976T (pl)
SG (1) SG11202101360VA (pl)
SI (1) SI3849976T1 (pl)
WO (1) WO2020053377A1 (pl)
ZA (1) ZA202100976B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4322955A1 (en) 2021-04-16 2024-02-21 Saniona A/S A gaba receptor modulator for use in the treatment of pain

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU675484B2 (en) 1993-03-24 1997-02-06 Neurosearch A/S Benzimidazole compounds, their use and preparation
GB9702524D0 (en) 1997-02-07 1997-03-26 Merck Sharp & Dohme Therapeutic agents
GB9813576D0 (en) 1998-06-24 1998-08-19 Merck Sharp & Dohme Therapeutic agents
ES2232416T3 (es) 1999-01-27 2005-06-01 MERCK SHARP & DOHME LTD. Derivados de triazolo-piridazina como ligandos para receptores gaba.
GB9921150D0 (en) 1999-09-07 1999-11-10 Merck Sharp & Dohme Therapeutic agents
GB0208394D0 (en) 2002-04-11 2002-05-22 Merck Sharp & Dohme Therapeutic agents
GB0208392D0 (en) 2002-04-11 2002-05-22 Merck Sharp & Dohme Therapeutic compounds
GB0212048D0 (en) 2002-05-24 2002-07-03 Merck Sharp & Dohme Therapeutic agents
EP1613618A2 (en) 2003-04-03 2006-01-11 Neurosearch A/S BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABA- sb A /sb RECEPTOR COMPLEX
TWI391381B (zh) 2006-03-24 2013-04-01 Neurosearch As 新穎的苯并咪唑衍生物、含有其之醫藥組成物、及其於製造藥物之用途
TW201029986A (en) 2008-11-14 2010-08-16 Neurosearch As Novel compounds
JP7115746B2 (ja) * 2016-01-27 2022-08-09 ウニヴェルズィテート・ツューリヒ 掻痒の処置のためのgabaa受容体モジュレーターの使用

Also Published As

Publication number Publication date
CN112714765B (zh) 2023-06-30
MX2021003010A (es) 2021-05-27
EP3849976B1 (en) 2022-10-26
US11396510B2 (en) 2022-07-26
AU2019338236A1 (en) 2021-05-20
WO2020053377A1 (en) 2020-03-19
IL281335A (en) 2021-04-29
FI3849976T3 (fi) 2023-02-19
IL281335B1 (en) 2024-03-01
CN112714765A (zh) 2021-04-27
EA202190717A1 (ru) 2021-09-22
JP2022500445A (ja) 2022-01-04
BR112021004661A2 (pt) 2021-06-01
EP3849976A1 (en) 2021-07-21
PH12021550299A1 (en) 2021-10-25
SI3849976T1 (sl) 2023-03-31
DK3849976T3 (da) 2023-01-23
LT3849976T (lt) 2023-02-10
PT3849976T (pt) 2023-01-13
US20210332042A1 (en) 2021-10-28
KR20210061338A (ko) 2021-05-27
HRP20230067T1 (hr) 2023-03-17
CA3110283A1 (en) 2020-03-19
ES2935705T3 (es) 2023-03-09
HUE060943T2 (hu) 2023-04-28
SG11202101360VA (en) 2021-03-30
JP7353663B2 (ja) 2023-10-02
ZA202100976B (en) 2022-08-31

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