JPWO2020006157A5 - - Google Patents
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- Publication number
- JPWO2020006157A5 JPWO2020006157A5 JP2020571383A JP2020571383A JPWO2020006157A5 JP WO2020006157 A5 JPWO2020006157 A5 JP WO2020006157A5 JP 2020571383 A JP2020571383 A JP 2020571383A JP 2020571383 A JP2020571383 A JP 2020571383A JP WO2020006157 A5 JPWO2020006157 A5 JP WO2020006157A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- alkyl
- unsubstituted
- optionally substituted
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862690791P | 2018-06-27 | 2018-06-27 | |
| US62/690,791 | 2018-06-27 | ||
| PCT/US2019/039368 WO2020006157A1 (en) | 2018-06-27 | 2019-06-27 | Dot1l degrader and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021529174A JP2021529174A (ja) | 2021-10-28 |
| JPWO2020006157A5 true JPWO2020006157A5 (https=) | 2022-07-05 |
| JP2021529174A5 JP2021529174A5 (https=) | 2022-07-05 |
| JP7821573B2 JP7821573B2 (ja) | 2026-02-27 |
Family
ID=67263119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020571383A Active JP7821573B2 (ja) | 2018-06-27 | 2019-06-27 | Ｄｏｔ１ｌディグレーダーおよびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11634450B2 (https=) |
| EP (1) | EP3814365B1 (https=) |
| JP (1) | JP7821573B2 (https=) |
| AU (1) | AU2019294723B2 (https=) |
| CA (1) | CA3102856A1 (https=) |
| WO (1) | WO2020006157A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020205665C1 (en) | 2019-01-09 | 2025-10-02 | Dana-Farber Cancer Institute, Inc. | DOT1L degraders and uses thereof |
| US20240245787A1 (en) | 2021-04-13 | 2024-07-25 | President And Fellows Of Harvard College | E3 ligase binders and uses thereof |
| EP4419518A1 (en) * | 2021-10-18 | 2024-08-28 | Dana-Farber Cancer Institute, Inc. | Small molecules for dot1l degradation and uses thereof |
| WO2023215354A1 (en) * | 2022-05-03 | 2023-11-09 | Board Of Regents, The University Of Texas System | Menin proteolysis targeting chimeras (protacs) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014296532B2 (en) | 2013-07-29 | 2019-05-16 | Dana-Farber Cancer Institute, Inc. | DOT1L probes |
| US9458165B2 (en) * | 2014-08-27 | 2016-10-04 | Dana-Farber Cancer Institute, Inc. | DOT1L inhibitors |
-
2019
- 2019-06-27 EP EP19739837.3A patent/EP3814365B1/en active Active
- 2019-06-27 US US17/252,842 patent/US11634450B2/en active Active
- 2019-06-27 WO PCT/US2019/039368 patent/WO2020006157A1/en not_active Ceased
- 2019-06-27 AU AU2019294723A patent/AU2019294723B2/en active Active
- 2019-06-27 CA CA3102856A patent/CA3102856A1/en active Pending
- 2019-06-27 JP JP2020571383A patent/JP7821573B2/ja active Active
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