JPWO2019198505A1 - Pest repellents and pest repellent products - Google Patents
Pest repellents and pest repellent products Download PDFInfo
- Publication number
- JPWO2019198505A1 JPWO2019198505A1 JP2020513182A JP2020513182A JPWO2019198505A1 JP WO2019198505 A1 JPWO2019198505 A1 JP WO2019198505A1 JP 2020513182 A JP2020513182 A JP 2020513182A JP 2020513182 A JP2020513182 A JP 2020513182A JP WO2019198505 A1 JPWO2019198505 A1 JP WO2019198505A1
- Authority
- JP
- Japan
- Prior art keywords
- repellent
- pest
- pest repellent
- component
- ants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/02—Acyclic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/04—Oxygen or sulfur attached to an aliphatic side-chain of a carbocyclic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/06—Oxygen or sulfur directly attached to a cycloaliphatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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Abstract
特定外来アリに対して効果的に忌避作用を及ぼすことができる害虫忌避剤を提供する。ヒアリ類及び／又はカミアリ類に対する忌避成分として、以下の式（Ｉ）：で表されるピペリジン誘導体を含有する害虫忌避剤であり、上記式（Ｉ）において、Ｒは炭素数２〜６のアルコキシ基が好ましく、１−メチルプロポキシ基がより好ましく、忌避香料成分として、以下の（ａ）及び（ｂ）：（ａ）総炭素数８〜１６の炭化水素アルデヒド類及び／又は炭化水素ケトン類（ｂ）総炭素数８〜１２のモノテルペン系アルコール類及び／又は芳香族アルコール類の少なくとも一方をさらに含有することが好ましい。Provided is a pest repellent that can effectively repel specific foreign ants. It is a pest repellent containing a piperidine derivative represented by the following formula (I): as a repellent component against hydrangea and / or kamiari, and in the above formula (I), R is an alkoxy having 2 to 6 carbon atoms. The group is preferable, the 1-methylpropoxy group is more preferable, and the following (a) and (b): (a) hydrocarbon aldehydes and / or hydrocarbon ketones having a total carbon number of 8 to 16 are used as the repellent fragrance component. b) It is preferable to further contain at least one of a monoterpene-based alcohol having a total carbon number of 8 to 12 and / or an aromatic alcohol.
Description
本発明は、ヒアリ類及び／又はカミアリ類を忌避する害虫忌避剤、及び害虫忌避製品に関する。 The present invention relates to pest repellents and pest repellent products that repel fire ants and / or fire ants.
近年、特定外来生物に指定されている害虫が日本国内で発見され、大きな社会問題となっている。そのような特定外来生物として、例えば、ヒアリ類やカミアリ類（以下、「特定外来アリ」と総称する場合がある。ただし、本発明では、アルゼンチンアリは特定外来アリには含まれないものとする。）が知られている。特定外来アリは、在来アリとは種類が異なるアリ類であり、強い毒性や高い繁殖力を有することに特徴がある。このため、特定外来アリを発見した場合、それらを完全に駆除することは当然であるが、特定外来アリがヒトの生活圏に侵入することを未然に阻止する忌避対策を講じることが重要であり、急務とされている。 In recent years, pests designated as specific alien species have been discovered in Japan and have become a major social problem. Such specific alien organisms include, for example, fire ants and fire ants (hereinafter, may be collectively referred to as "specific alien ants". However, in the present invention, Argentine ants are not included in the specific alien ants. .)It has been known. Specific alien ants are ants of a different type from native ants, and are characterized by having strong toxicity and high fertility. For this reason, when specific alien ants are found, it is natural to completely eliminate them, but it is important to take repellent measures to prevent specific alien ants from invading the human living area. , Is urgent.
従来、アリ類を忌避するための薬剤として、例えば、天然精油を有効成分とした忌避剤が知られている（例えば、特許文献１を参照）。特許文献１には、アリ類の忌避剤の有効成分として、オークモス、オレンジフラワー油、サンダルウッド油、スペアミント油、タイムホワイト油、パチョウリ油、パルマローザ油、レモングラス油、ローレル油、ガーリック油、キンモクセイ油、ココナッツ油、シナモンリーフ油、ジル油（イノンド油）、タイムレッド油、トルーバルサム、バーチ油、ペルーバルサムが記載されている。 Conventionally, as an agent for repelling ants, for example, a repellent containing natural essential oil as an active ingredient is known (see, for example, Patent Document 1). Patent Document 1 describes oak moss, orange flower oil, sandal wood oil, spare mint oil, thyme white oil, pachori oil, palmarosa oil, lemongrass oil, laurel oil, garlic oil, and kinmokusei as active ingredients of ant repellents. Oils, coconut oils, cinnamon leaf oils, gills oils (inondo oils), thyme red oils, trobalsams, birch oils and peruvial balsams are listed.
また、ディート等の薬剤を用いてアリ類を防除する方法は、従来から行われている（例えば、特許文献２を参照）。ディートは、一般に蚊類等の双翅目害虫に対する忌避成分として使用されるものであるが、特許文献２によれば、アリ類等の膜翅目害虫も防除対象害虫の一つとして挙げられている。 Further, a method of controlling ants using a chemical such as DEET has been conventionally performed (see, for example, Patent Document 2). DEET is generally used as a repellent component against dipteran pests such as mosquitoes, but according to Patent Document 2, Membranous pests such as ants are also listed as one of the pests to be controlled. There is.
ところが、特定外来アリは、一般的な在来アリとは生態が大きく異なる。在来アリは、地中の他、枯れ木の内部等にもコロニー（巣）を形成し、比較的少数の家族単位で生命活動を営んでいる。一方、特定外来アリは、地中深くにコロニーを形成し、一つのコロニーの中に一匹の女王アリが存在する単女王制と、複数の女王アリが存在する多女王制との二種類の生態が知られている。特に、多女王制の生態を有する特定外来アリは、コロニー内の女王アリの個体数が多いほど繁殖力が高く、一つのコロニー内で最大４０００万匹ものアリが生命活動を営むこともある。 However, the ecology of specific exotic ants is very different from that of general native ants. Native ants form colonies (nests) not only in the ground but also inside dead trees, and carry out life activities in a relatively small number of family units. On the other hand, specific alien ants form colonies deep in the ground, and there are two types: a single queen system in which one queen ant exists in one colony, and a multi-queen system in which multiple queen ants exist. The ecology is known. In particular, the specific alien ants that have a multi-queen ecology have higher fertility as the number of queen ants in the colony increases, and up to 40 million ants may carry out life activities in one colony.
このように、特定外来アリは、在来アリとは活動規模や行動パターンが大きく異なるため、特定外来アリのコロニーに、従来用いられていた特許文献１に記載のアリ類の忌避剤（有効成分：天然精油）や、特許文献２に記載の防除剤（有効成分：ディート）を適用しても、特定外来アリを完全に忌避又は防除できるとは限らず、そればかりか、一部の女王アリが忌避剤又は防除剤の存在をいち早く察知し、それらの忌避効果又は防除効果を免れるためコロニーから離散してしまう可能性もある。 As described above, since the specific alien ants have a significantly different activity scale and behavior pattern from the conventional ants, the ant repellent (active ingredient) described in Patent Document 1 conventionally used for the colony of the specific alien ants. : Natural essential oil) and the control agent (active ingredient: Diet) described in Patent Document 2 do not always completely repel or control specific foreign ants, and not only some queen ants. May detect the presence of repellents or control agents early and may disperse from the colony to avoid their repellent or control effects.
本発明は、上記の問題点に鑑みてなされたものであり、特定外来アリに対して効果的に忌避作用を及ぼすことができる害虫忌避剤、及び害虫忌避製品を提供することを目的とする。 The present invention has been made in view of the above problems, and an object of the present invention is to provide a pest repellent agent and a pest repellent product capable of effectively exerting a repellent action on a specific foreign ant.
上記課題を解決するための本発明にかかる害虫忌避剤の特徴構成は、
ヒアリ類及び／又はカミアリ類に対する忌避成分として、以下の式（Ｉ）：
As a repellent component against fire ants and / or fire ants, the following formula (I):
本構成の害虫忌避剤によれば、上記式（Ｉ）で表されるピペリジン誘導体は、従来、蚊類、蚋類、チョウバエ類、イエバエ類、サシバエ類、ゴキブリ類等の害虫に対して忌避効果を示すことが知られていたが、ヒアリ類、カミアリ類等の特定外来アリに対しても優れた忌避効果を示すという新たな知見に基づき、ヒアリ類及び／又はカミアリ類を忌避するための有効成分（忌避成分）となり得ることが判明した。従って、本構成のピペリジン誘導体を含有する害虫忌避剤は、ヒアリ類及び／又はカミアリ類用の害虫忌避剤として有用であり、本構成の害虫忌避剤を使用すれば、ヒアリ類及び／又はカミアリ類による被害を低減することができる。 According to the pest repellent of this constitution, the piperidine derivative represented by the above formula (I) has conventionally been effective against pests such as mosquitoes, fire ants, gnats, houseflies, stable flies and cockroaches. However, based on the new finding that it shows an excellent repellent effect against specific foreign ants such as fire ants and mosquitoes, it is effective for repelling fire ants and / or mosquitoes. It has been found that it can be an ingredient (repellent ingredient). Therefore, the pest repellent containing the piperidine derivative of this constitution is useful as a pest repellent for fire ants and / or fire ants, and if the pest repellent of this constitution is used, fire ants and / or fire ants Damage caused by fire ants can be reduced.
本発明にかかる害虫忌避剤において、
前記式（Ｉ）において、Ｒは炭素数２〜６のアルコキシ基であることが好ましい。In the pest repellent according to the present invention
In the formula (I), R is preferably an alkoxy group having 2 to 6 carbon atoms.
本構成の害虫忌避剤によれば、上記式（Ｉ）で表されるピペリジン誘導体において、置換基Ｒとして炭素数２〜６のアルコキシ基を選択することにより、ヒアリ類及び／又はカミアリ類に対してより優れた忌避効果を有する害虫忌避剤となり得る。 According to the pest repellent having the present constitution, in the piperidine derivative represented by the above formula (I), by selecting an alkoxy group having 2 to 6 carbon atoms as the substituent R, the fire ants and / or the turtles can be treated. It can be a pest repellent with a better repellent effect.
本発明にかかる害虫忌避剤において、
前記Ｒは、１−メチルプロポキシ基であることが好ましい。In the pest repellent according to the present invention
The R is preferably a 1-methylpropoxy group.
本構成の害虫忌避剤によれば、上記式（Ｉ）で表されるピペリジン誘導体において、置換基Ｒとして１−メチルプロポキシ基を選択することにより、当該ピペリジン誘導体は害虫忌避効果が高く且つ人体安全性に優れたイカリジンとして、ヒアリ類及び／又はカミアリ類に対してさらに優れた忌避効果を有する害虫忌避剤となり得る。 According to the pest repellent having the present constitution, by selecting the 1-methylpropoxy group as the substituent R in the piperidine derivative represented by the above formula (I), the piperidine derivative has a high pest repellent effect and is safe for the human body. As an icaridine having excellent properties, it can be a pest repellent having an even more excellent repellent effect on fire ants and / or fire ants.
本発明にかかる害虫忌避剤において、
忌避香料成分として、以下の（ａ）及び（ｂ）：
（ａ）総炭素数８〜１６の炭化水素アルデヒド類及び／又は炭化水素ケトン類
（ｂ）総炭素数８〜１２のモノテルペン系アルコール類及び／又は芳香族アルコール類の少なくとも一方をさらに含有することが好ましい。In the pest repellent according to the present invention
As the repellent fragrance component, the following (a) and (b):
(A) Hydrocarbon aldehydes and / or hydrocarbon ketones having a total carbon number of 8 to 16 (b) Monoterpene alcohols and / or aromatic alcohols having a total carbon number of 8 to 12 are further contained. Is preferable.
本構成の害虫忌避剤によれば、上記式（Ｉ）で表されるピペリジン誘導体の他に、上記（ａ）及び（ｂ）の少なくとも一方の忌避香料成分をさらに含有することで、ピペリジン誘導体と忌避香料成分との相乗効果により、ヒアリ類及び／又はカミアリ類を強力に忌避することができる。また、ピペリジン誘導体は、無香性であることから、忌避香料成分と組み合わせた場合、当該忌避香料成分の本来の香りに影響することは殆どない。従って、ピペリジン誘導体は、忌避香料成分との相性が良い忌避成分であると言える。 According to the pest repellent having the present constitution, in addition to the piperidine derivative represented by the above formula (I), the piperidine derivative can be obtained by further containing at least one of the repellent fragrance components (a) and (b). Fire ants and / or fire ants can be strongly repelled by the synergistic effect with the repellent fragrance component. Further, since the piperidine derivative is fragrance-free, when combined with the repellent fragrance component, it hardly affects the original scent of the repellent fragrance component. Therefore, it can be said that the piperidine derivative is a repellent component that is compatible with the repellent fragrance component.
本発明にかかる害虫忌避剤において、
前記（ａ）の忌避香料成分は、デカナール、ウンデカナール、ドデカナール、２−メチルウンデカナール、トリデカナール、１０−ウンデセナール、シトロネラール、シトラール、ネラール、フェニルアセトアルデヒド、シンナミックアルデヒド、α−アミルシンナミックアルデヒド、α−ヘキシルシンナミックアルデヒド、リリアール、ペリルアルデヒド、トリベルタール、クミンアルデヒド、ヘリオトロピン、トリデカノン、ｌ−カルボン、メントン、プレゴン、シス−ジャスモン、ジヒドロジャスモン、α−ダマスコン、β−ダマスコン、δ−ダマスコン、α−イオノン、β−イオノン、２−ペンチルシクロペンタノン、２−ヘキシルシクロペンタノン、２−ヘプチルシクロペンタノン、メチルベンジルケトン、及びメチルスチリルケトンからなる群から選択される少なくとも一つであり、
前記（ｂ）の忌避香料成分は、リナロール、デヒドロリナロール、ジヒドロミルセノール、ゲラニオール、ネロール、シトロネロール、メントール、テルピネオール、テルピネン−４−オール、イソプレゴール、ボルネオール、１−フェニルエチルアルコール、２−フェニルエチルアルコール、シンナミックアルコール、チモール、及びオイゲノールからなる群から選択される少なくとも一つであることが好ましい。In the pest repellent according to the present invention
The repellent fragrance component of (a) is decanal, undecalal, dodecanal, 2-methylundecanal, tridecanal, 10-undecaneal, citroneral, citral, neral, phenylacetaldehyde, synamic aldehyde, α-amylcinnamic aldehyde, α-Hexyl cinnamic aldehyde, lilial, peryl aldehyde, trivertal, cumin aldehyde, heliotropin, tridecanon, l-carboxylic, menton, pregon, cis-jasmon, dihydrojasmon, α-damascon, β-damascon, δ-damascon, α At least one selected from the group consisting of −ionone, β-ionone, 2-pentylcyclopentanone, 2-hexylcyclopentanone, 2-heptylcyclopentanone, methylbenzylketone, and methylstyrylketone.
The repellent fragrance component of (b) is linalool, dehydrolinalol, dihydromilsenol, geraniol, nerol, citronellol, menthol, terpineol, terpine-4-ol, isopregol, borneol, 1-phenylethyl alcohol, 2-phenylethyl. It is preferably at least one selected from the group consisting of alcohols, synamic alcohols, timols, and eugenols.
本構成の害虫忌避剤によれば、上記（ａ）の忌避香料成分と上記（ｂ）の忌避香料成分とを、上記の各選択肢の中から選択することで、ヒアリ類及び／又はカミアリ類をより強力に忌避することができる害虫忌避剤となり得る。 According to the pest repellent of this configuration, fire ants and / or fire ants can be selected by selecting the repellent fragrance component of (a) and the repellent fragrance component of (b) from each of the above options. It can be a pest repellent that can repel more strongly.
本発明にかかる害虫忌避剤において、
前記（ａ）の忌避香料成分と前記（ｂ）の忌避香料成分とを、（ａ）／（ｂ）＝０．１／１〜９／１の配合比率（重量比）で含有することが好ましい。In the pest repellent according to the present invention
It is preferable that the repellent fragrance component of (a) and the repellent fragrance component of (b) are contained in a blending ratio (weight ratio) of (a) / (b) = 0.1 / 1 to 9/1. ..
本構成の害虫忌避剤によれば、上記（ａ）の忌避香料成分と上記（ｂ）の忌避香料成分とを、上記の配合比率（重量比）で含有することで、異なる種類の忌避香料成分によって増強された忌避効果（相乗効果）が得られ、また芳香としても心地よい害虫忌避剤となり得る。 According to the pest repellent component of this constitution, the repellent fragrance component of the above (a) and the repellent fragrance component of the above (b) are contained in the above-mentioned compounding ratio (weight ratio), so that different kinds of repellent fragrance components are contained. The repellent effect (synergistic effect) enhanced by the above can be obtained, and the pest repellent can be a pleasant fragrance.
本発明にかかる害虫忌避剤において、
忌避効果持続成分として、グリコール類及び／又はグリコールエーテル類をさらに含有することが好ましい。In the pest repellent according to the present invention
It is preferable to further contain glycols and / or glycol ethers as a repellent effect lasting component.
本構成の害虫忌避剤によれば、グリコール類及び／又はグリコールエーテル類はピペリジン誘導体よりも蒸気圧が高い物質であるため、グリコール類及び／又はグリコールエーテル類によってピペリジン誘導体の過剰な揮散が抑制される。その結果、ピペリジン誘導体によるヒアリ類及び／又はカミアリ類に対する忌避効果が長期に亘って持続する。 According to the pest repellent of this constitution, glycols and / or glycol ethers are substances having a higher vapor pressure than piperidine derivatives, so that glycols and / or glycol ethers suppress excessive volatilization of the piperidine derivative. To. As a result, the repellent effect of the piperidine derivative on fire ants and / or fire ants is sustained for a long period of time.
本発明にかかる害虫忌避剤において、
殺虫成分を実質的に含有しないことが好ましい。In the pest repellent according to the present invention
It is preferable that it contains substantially no insecticidal component.
本構成の害虫忌避剤によれば、殺虫成分を実質的に含有しなくても、上記式（Ｉ）で表されるピペリジン誘導体によって、ヒアリ類及び／又はカミアリ類に対する忌避効果が得られる。このため、殺虫成分に過敏な消費者にとっても日常的な使用への抵抗が小さい害虫忌避剤となり得る。また、害虫がディート等の従来の忌避成分に耐性を有することになった場合にも、忌避効果が期待できる。 According to the pest repellent having the present constitution, the piperidine derivative represented by the above formula (I) can obtain a repellent effect on fire ants and / or fire ants even if it does not substantially contain an insecticidal component. Therefore, it can be a pest repellent with low resistance to daily use even for consumers who are sensitive to insecticidal components. Further, even when the pest becomes resistant to the conventional repellent component such as DEET, the repellent effect can be expected.
上記課題を解決するための本発明にかかる害虫忌避製品の特徴構成は、
上記何れか一つの害虫忌避剤を含有する液状製剤、ジェル状製剤、又は固形剤として構成されることにある。The characteristic configuration of the pest repellent product according to the present invention for solving the above problems is
It is to be configured as a liquid preparation, a gel preparation, or a solid preparation containing any one of the above pest repellents.
本構成の害虫忌避製品によれば、本発明の害虫忌避剤を含有しているため、ヒアリ類及び／又はカミアリ類を忌避するための実用的且つ有用な害虫忌避製品となる。また、製品形態として、液状製剤、ジェル状製剤、又は固形剤を採用することで、使い勝手の良い害虫忌避製品となり得る。 According to the pest repellent product of the present invention, since it contains the pest repellent of the present invention, it is a practical and useful pest repellent product for repelling fire ants and / or fire ants. Further, by adopting a liquid preparation, a gel preparation, or a solid preparation as the product form, it can be an easy-to-use pest repellent product.
本発明は、従来、蚊類、蚋類、チョウバエ類、イエバエ類、サシバエ類、ゴキブリ類等の害虫に対して忌避効果を示すことが知られていたピペリジン誘導体について、本発明者らが鋭意研究を重ねたところ、このピペリジン誘導体は、予期せぬことに、現在社会問題となっているヒアリ類やカミアリ類などの特定外来アリに対して特異的に優れた忌避効果を有するという新たな知見が得られ、これに基づいてヒアリ類及び／又はカミアリ類に対する害虫忌避剤、及び害虫忌避製品を完成するに至ったものである。以下、本発明の害虫忌避剤、及び害虫忌避製品について説明する。ただし、本発明は、以下の実施形態の構成や実施例の内容に限定されることを意図するものではない。 The present inventors have diligently studied a piperidine derivative which has been known to have a repellent effect on pests such as mosquitoes, fire ants, fire ants, houseflies, stable flies and cockroaches. As a result of repeated investigations, it was unexpectedly found that this piperidine derivative has an excellent repellent effect specifically against specific foreign ants such as fire ants and stable flies, which are currently social problems. Based on this, a pest repellent for fire ants and / or ants and a pest repellent product have been completed. Hereinafter, the pest repellent and the pest repellent product of the present invention will be described. However, the present invention is not intended to be limited to the configuration of the following embodiments or the contents of the examples.
〔害虫忌避剤〕
本発明の害虫忌避剤は、ヒアリ類及び／又はカミアリ類に対する忌避成分として、以下の式（Ｉ）：
The pest repellent of the present invention has the following formula (I): as a repellent component against fire ants and / or fire ants.
Ｒが炭素数２〜６のアルキル基である場合、エチル基、ｎ−プロピル基、イソプロピル基、ｎ−ブチル基、ｓｅｃ−ブチル基、イソブチル基、ｔｅｒｔ−ブチル基、ペンチル基、ヘキシル基等が挙げられる。Ｒが炭素数２〜６のアルコキシ基である場合、エトキシ基、ｎ−プロポキシ基、イソプロポキシ基、ｎ−ブトキシ基、ｔｅｒｔ−ブトキシ基、１−メチルプロポキシ基、２−メチルプロポキシ基等が挙げられる。これらの置換基Ｒうち、最も好ましいものは、Ｒが炭素数４のアルコキシ基である１−メチルプロポキシ基であり、これは、以下の式（ＩＩ）：
上記式（Ｉ）で表されるピペリジン誘導体は、害虫忌避成分として従来から一般に使用されているディートと比べると、蒸気圧が若干低い物質である。例えば、代表的なピペリジン誘導体である上記式（ＩＩ）で表されるイカリジンの蒸気圧は０．０５９Ｐａ（２５℃）であり、ディートの蒸気圧は０．２３Ｐａ（２５℃）である。それにも関わらず、後述の実施例の結果が示すように、ピペリジン誘導体を含有する本発明の害虫忌避剤は、ヒアリ類やカミアリ類などの特定外来アリに対して優れた忌避効果を示した。その一方で、ディートを含有する従来の害虫忌避剤は、ピペリジン誘導体を含有する本発明の害虫忌避剤と比べて、特定外来アリに対する忌避効果は著しく劣るものであった。これは、ピペリジン誘導体の忌避効果は、有効成分（忌避成分）の揮散による空間忌避効果よりも、むしろ有効成分の害虫への接触による接触忌避効果に依るところが大きいためと推測される。 The piperidine derivative represented by the above formula (I) is a substance having a slightly lower vapor pressure than DEET, which has been generally used as a pest repellent component. For example, the vapor pressure of icaridin represented by the above formula (II), which is a typical piperidine derivative, is 0.059 Pa (25 ° C.), and the vapor pressure of DEET is 0.23 Pa (25 ° C.). Nevertheless, as the results of Examples described below show, the pest repellent of the present invention containing a piperidine derivative showed an excellent repellent effect on specific foreign ants such as fire ants and fire ants. On the other hand, the conventional pest repellent containing DEET has a significantly inferior repellent effect on specific foreign ants as compared with the pest repellent of the present invention containing a piperidine derivative. It is presumed that this is because the repellent effect of the piperidine derivative depends more on the contact repellent effect due to the contact of the active ingredient with pests than on the spatial repellent effect due to the volatilization of the active ingredient (repellent ingredient).
ところで、本発明の害虫忌避剤は、有効成分として含有するピペリジン誘導体のみで、特定外来アリに対して実用上問題の無い忌避効果を示すことができるが、空間忌避効果によって接触忌避効果を補った場合には、相乗効果によって特定外来アリをより強力に忌避することが可能となる。そこで、本発明の害虫忌避剤においては、上記式（Ｉ）で表されるピペリジン誘導体の他に、忌避香料成分を併用することが有効である。なお、ピペリジン誘導体は、無香性である（虫除け剤特有の臭いが無い）ことから、忌避香料成分と組み合わせた場合、当該忌避香料成分の本来の香りに影響することは殆どない。従って、ピペリジン誘導体は、忌避香料成分との相性が良い忌避成分であると言える。 By the way, the pest repellent of the present invention can show a practically no problem repellent effect against a specific foreign ant only by a piperidine derivative contained as an active ingredient, but the contact repellent effect is supplemented by the spatial repellent effect. In some cases, the synergistic effect makes it possible to repel specific foreign ants more strongly. Therefore, in the pest repellent of the present invention, it is effective to use a repellent fragrance component in combination with the piperidine derivative represented by the above formula (I). Since the piperidine derivative is fragrance-free (has no odor peculiar to insect repellents), it has almost no effect on the original scent of the repellent fragrance component when combined with the repellent fragrance component. Therefore, it can be said that the piperidine derivative is a repellent component that is compatible with the repellent fragrance component.
ピペリジン誘導体と組み合わせることが可能な忌避香料成分は、（ａ）総炭素数８〜１６の炭化水素アルデヒド類及び／又は炭化水素ケトン類、及び（ｂ）総炭素数８〜１２のモノテルペン系アルコール類及び／又は芳香族アルコール類である。上記（ａ）の忌避香料成分及び上記（ｂ）の忌避香料成分は、どちらか一方のみを使用してもよいし、両方を使用してもよい。 The repellent fragrance components that can be combined with the piperidine derivative are (a) hydrocarbon aldehydes and / or hydrocarbon ketones having a total carbon number of 8 to 16, and (b) a monoterpene alcohol having a total carbon number of 8 to 12. And / or aromatic alcohols. As the repellent fragrance component of (a) and the repellent fragrance component of (b) above, only one of them may be used, or both may be used.
上記（ａ）の忌避香料成分を例示すると、デカナール、ウンデカナール、ドデカナール、２−メチルウンデカナール、トリデカナール、１０−ウンデセナール、シトロネラール、シトラール、ネラール、フェニルアセトアルデヒド、シンナミックアルデヒド、α−アミルシンナミックアルデヒド、α−ヘキシルシンナミックアルデヒド、リリアール、ペリルアルデヒド、トリベルタール、クミンアルデヒド、ヘリオトロピン、トリデカノン、ｌ−カルボン、メントン、プレゴン、シス−ジャスモン、ジヒドロジャスモン、α−ダマスコン、β−ダマスコン、δ−ダマスコン、α−イオノン、β−イオノン、２−ペンチルシクロペンタノン、２−ヘキシルシクロペンタノン、２−ヘプチルシクロペンタノン、メチルベンジルケトン、及びメチルスチリルケトンが挙げられる。これらの（ａ）の忌避香料成分は、単独で用いてもよいし、複数種を組み合わせて用いてもよい。 To exemplify the repellent fragrance component of (a) above, decanal, undecalal, dodecanal, 2-methylundecanal, tridecalal, 10-undecaneal, citroneral, citral, neral, phenylacetaldehyde, synamic aldehyde, α-amyl synnamic. Aldehyde, α-hexyl cinnamic aldehyde, lilial, peryl aldehyde, tribertal, cumin aldehyde, heliotropin, tridecanone, l-carboxylic, menton, pregon, cis-jasmon, dihydro jasmon, α-damascon, β-damascon, δ-damascon , Α-ionone, β-ionone, 2-pentylcyclopentanone, 2-hexylcyclopentanone, 2-heptylcyclopentanone, methylbenzylketone, and methylstyrylketone. These repellent fragrance components (a) may be used alone or in combination of two or more.
上記（ｂ）の忌避香料成分を例示すると、リナロール、デヒドロリナロール、ジヒドロミルセノール、ゲラニオール、ネロール、シトロネロール、メントール、テルピネオール、テルピネン−４−オール、イソプレゴール、ボルネオール、１−フェニルエチルアルコール、２−フェニルエチルアルコール、シンナミックアルコール、チモール、及びオイゲノールが挙げられる。これらの（ｂ）の忌避香料成分は、単独で用いてもよいし、複数種を組み合わせて用いてもよい。 Examples of the repellent fragrance component of (b) above are linalool, dehydrolinalol, dihydromyrsenol, geraniol, nerol, citronellol, menthol, terpineol, terpine-4-ol, isopulegol, borneol, 1-phenylethyl alcohol, 2- Examples include phenylethyl alcohol, synamic alcohol, timol, and eugenol. These repellent fragrance components (b) may be used alone or in combination of two or more.
上記（ａ）の忌避香料成分と上記（ｂ）の忌避香料成分とを併用する場合、両者の配合比率（ａ）／（ｂ）は、重量比で０．１／１〜９／１に設定することが好ましく、０．５／１〜１．４／１に設定することがより好ましい。配合比率（ａ）／（ｂ）が上記の範囲にあれば、異なる種類の忌避香料成分（ａ）及び（ｂ）によって増強された忌避効果（相乗効果）が得られ、また芳香としても心地よいものとなる。配合比率（ａ）／（ｂ）が０．１／１より小さい場合、或いは配合比率（ａ）／（ｂ）が９／１より大きい場合、異なる種類の忌避香料成分（ａ）及び（ｂ）を併用したことによる相乗効果を享受し難くなる。 When the repellent fragrance component of the above (a) and the repellent fragrance component of the above (b) are used in combination, the blending ratio (a) / (b) of both is set to 0.1 / 1 to 9/1 by weight. It is preferable to set the value to 0.5 / 1 to 1.4 / 1. If the blending ratio (a) / (b) is within the above range, a repellent effect (synergistic effect) enhanced by different types of repellent fragrance components (a) and (b) can be obtained, and the fragrance is also pleasant. It becomes. When the compounding ratio (a) / (b) is smaller than 0.1 / 1, or when the compounding ratio (a) / (b) is larger than 9/1, different types of repellent fragrance components (a) and (b) It becomes difficult to enjoy the synergistic effect of using in combination.
本発明の害虫忌避剤は、上記（ａ）及び（ｂ）とは別の忌避香料成分として、（ｃ）総炭素数８〜１６の炭化水素エステル類を含有することも可能である。上記（ｃ）の忌避香料成分は、上記（ａ）の忌避香料成分や上記（ｂ）の忌避香料成分と協働して、特定外来アリに対する忌避効果の増強に寄与し得る成分である。 The pest repellent of the present invention can also contain (c) hydrocarbon esters having a total carbon number of 8 to 16 as a repellent fragrance component different from the above (a) and (b). The repellent fragrance component of (c) is a component that can contribute to the enhancement of the repellent effect on specific foreign ants in cooperation with the repellent fragrance component of (a) and the repellent fragrance component of (b).
上記（ｃ）の忌避香料成分を例示すると、デシルアセテート、リナリルアセテート、ゲラニルアセテート、シトロネリルアセテート、メンチルアセテート、テルピニルアセテート、ネピルアセテート、ｐ−ｔ−ブチルシクロヘキシルアセテート、トリシクロデセニルアセテート、トリシクロデセニルプロピオネート、トリシクロデセニルイソブチレート、ベンジルアセテート、フェニルエチルアセテート、スチラリルアセテート、シンナミルアセテート、シンナミルプロピオネート、アリルヘキサノエート、アリルヘプタノエート、メチルベンゾエート、エチルベンゾエート、３−ヘキセニルベンゾエート、ベンジルベンゾエート、メチルシンナメート、エチルシンナメート、メチルサリシネート、エチルサリシネート、アミルサリシネート、メチルジャスモネート、及びメチルジヒドロジャスモネートが挙げられる。これらの（ｃ）の忌避香料成分は、単独で用いてもよいし、複数種を組み合わせて用いてもよい。 To exemplify the repellent fragrance component of (c) above, decyl acetate, linaryl acetate, geranyl acetate, citronellyl acetate, mentyl acetate, terpinyl acetate, nepil acetate, pt-butylcyclohexyl acetate, tricyclodecenyl acetate. Acetate, tricyclodecenyl propionate, tricyclodecenyl isobutyrate, benzyl acetate, phenylethyl acetate, styralyl acetate, cinnamyl acetate, cinnamyl propionate, allyl hexanoate, allyl heptanoate , Methyl benzoate, ethyl benzoate, 3-hexenyl benzoate, benzyl benzoate, methyl cinnamate, ethyl cinnamate, methyl salicinate, ethyl salicinate, amyl salicinate, methyl jasmonate, and methyl dihydro jasmonate. Can be mentioned. These repellent fragrance components (c) may be used alone or in combination of two or more.
本発明の害虫忌避剤は、必要に応じて、忌避香料成分以外の成分を含有することも可能である。そのような成分として、ｄ−リモネン、α−ピネン、β−ピネン等の炭化水素類、イソアミルフェニルエチルエーテル、リナロールオキサイド、１，８−シネオール、ローズオキサイド、ジフェニルエーテル、マグノラン、ルバフラン、ジヒドロインデニル−２，４−ジオキサン等の炭化水素エーテル類、２，６−ジメチル−３−エチルピラジン、シトロネリルニトリル、ステモン、ｏ−アミノアセトフェノン等の含窒素化合物類、サンダルウッド油、スペアミント油、タイムホワイト油、バチョウリ油、ガーリック油、シナモンリーフ油、タイムレッド油、ジャスミン油、ネロリ油、ベルガモット油、オレンジ油、ゼラニウム油、プチグレン油、レモン油、レモングラス油、シナモン油、ユーカリ油、レモンユーカリ油等の精油類等が挙げられる。 The pest repellent of the present invention can also contain components other than the repellent fragrance component, if necessary. As such components, hydrocarbons such as d-lymonene, α-pinene, β-pinene, isoamylphenyl ethyl ether, linalol oxide, 1,8-cineole, rose oxide, diphenyl ether, magnolan, ruvafuran, dihydroindenyl- Hydrocarbon ethers such as 2,4-dioxane, nitrogen-containing compounds such as 2,6-dimethyl-3-ethylpyrazine, citronellylnitrile, stemon, o-aminoacetophenone, sandalwood oil, spearmint oil, thyme white oil , Bacholi oil, garlic oil, cinnamon leaf oil, thyme red oil, jasmine oil, neroli oil, bergamot oil, orange oil, geranium oil, petitgrain oil, lemon oil, lemongrass oil, cinnamon oil, eucalyptus oil, lemon eucalyptus oil, etc. Essential oils and the like.
さらに、本発明の害虫忌避剤は、グリコール類及び／又はグリコールエーテル類を含有することが有効である。グリコール類及び／又はグリコールエーテル類は、忌避成分又は忌避香料成分の溶剤としてのみならず、忌避成分又は忌避香料成分の忌避効果を持続させる忌避効果持続成分として作用する。これは、グリコール類及び／又はグリコールエーテル類はピペリジン誘導体よりも蒸気圧が高い物質であることに起因する。グリコール類及び／又はグリコールエーテル類をピペリジン誘導体に添加すると、ピペリジン誘導体の過剰な揮散が抑制され、その結果、ピペリジン誘導体による特定外来アリに対する忌避効果が長期に亘って持続し得る。 Further, it is effective that the pest repellent of the present invention contains glycols and / or glycol ethers. Glycos and / or glycol ethers act not only as a solvent for the repellent component or the repellent fragrance component, but also as a repellent effect-sustaining component that sustains the repellent effect of the repellent component or the repellent fragrance component. This is because glycols and / or glycol ethers are substances having a higher vapor pressure than piperidine derivatives. When glycols and / or glycol ethers are added to the piperidine derivative, excessive volatilization of the piperidine derivative is suppressed, and as a result, the repellent effect of the piperidine derivative on specific foreign ants can be maintained for a long period of time.
忌避効果持続成分として使用可能なグリコール類及び／又はグリコールエーテル類を例示すると、プロピレングリコール（１０．７Ｐａ）、ジプロピレングリコール（１．３Ｐａ）、トリプロピレングリコール（０．６７Ｐａ）、ジエチレングリコール（３Ｐａ）、トリエチレングリコール（１Ｐａ）、１，３−ブチレングリコール、ヘキシレングリコール（６．７Ｐａ）、ベンジルグリコール（２．７Ｐａ）、ジエチレングリコールモノブチルエーテル（３Ｐａ）、ジプロピレングリコールモノブチルエーテル、及びトリプロピレングリコールモノメチルエーテルが挙げられる。なお、各物質名の後のカッコ内に記載する数値は、２０℃における蒸気圧である。これらのグリコール類及び／又はグリコールエーテル類のうち、好ましい忌避効果持続成分は、ジプロピレングリコールである。忌避効果持続成分の含有量は、忌避成分及び忌避香料成分の含有量の０．２〜１０倍とすることが好ましい。 Examples of glycols and / or glycol ethers that can be used as a repellent effect lasting component include propylene glycol (10.7 Pa), dipropylene glycol (1.3 Pa), tripropylene glycol (0.67 Pa), and diethylene glycol (3 Pa). , Triethylene glycol (1Pa), 1,3-butylene glycol, hexylene glycol (6.7Pa), benzyl glycol (2.7Pa), diethylene glycol monobutyl ether (3Pa), dipropylene glycol monobutyl ether, and tripropylene glycol monomethyl. Includes ether. The numerical value described in parentheses after each substance name is the vapor pressure at 20 ° C. Among these glycols and / or glycol ethers, a preferable repellent effect lasting component is dipropylene glycol. The content of the repellent effect lasting component is preferably 0.2 to 10 times the content of the repellent component and the repellent fragrance component.
本発明の害虫忌避剤には、特定外来アリに対する忌避効果に支障を来たさない物質及び分量であれば、消臭成分、除菌成分、抗菌成分等の機能性成分を配合してもよい。消臭成分としては、イネ科、ツバキ科、イチョウ科、モクセイ科、クワ科、ミカン科、キントラノオ科、カキノキ科などの植物抽出物が代表的である。また、「緑の香り」と呼ばれる青葉アルコールや青葉アルデヒド等を配合することで、リラックス効果を付与することもできる。 The pest repellent of the present invention may contain functional components such as a deodorant component, a sterilizing component, and an antibacterial component as long as the substance and amount do not interfere with the repellent effect on specific foreign ants. .. Typical deodorant components are plant extracts such as Gramineae, Theaceae, Ginkgoaceae, Oleaceae, Moraceae, Rutaceae, Malpighiaceae, and Ebenaceae. In addition, a relaxing effect can be imparted by blending green leaf alcohol, green leaf aldehyde, or the like, which is called "green scent".
本発明の害虫忌避剤は、その趣旨から殺虫成分を実質的に含有しないものとすることが好ましい。ここで、「実質的に含有しない」とは、どのような場合においても殺虫成分の含有量が厳密に０％であることを意味するものではない。例えば、意図せずして極微量の殺虫成分が含まれることになった場合や、意図的に極微量の殺虫成分を含有させたとしても当該殺虫成分としての作用を奏しない場合は、殺虫成分を実質的に含有しない害虫忌避剤であるものと見なす。意図せずして極微量の殺虫成分が含まれることとなった場合の例としては、害虫忌避剤の製造設備において、以前に殺虫成分を含有する別の製品を製造していた場合、容器や配管に付着していた極微量の殺虫成分がコンタミとして害虫忌避剤に混入するケースや、製造室内の空気中に浮遊又は揮散していた殺虫成分が製造中の害虫忌避剤に吸収されて混入するケース等が挙げられる。このような場合は、殺虫成分を極微量含むものであっても、殺虫成分を実質的に含有しない害虫忌避剤として取り扱う。 For that purpose, the pest repellent of the present invention preferably contains substantially no insecticidal component. Here, "substantially free" does not mean that the content of the insecticidal component is strictly 0% in any case. For example, if an extremely small amount of an insecticidal component is unintentionally contained, or if an extremely small amount of an insecticidal component is intentionally contained but does not act as the insecticidal component, the insecticidal component Is considered to be a pesticide that does not substantially contain. An example of an unintentional inclusion of a very small amount of an insecticide is a container or a pest repellent manufacturing facility that previously produced another product containing the insecticide. In some cases, a very small amount of insecticide adhering to the pipe is mixed with the pest repellent as a contamination, or the insecticide suspended or volatilized in the air in the manufacturing room is absorbed by the pest repellent during manufacturing and mixed. Examples include cases. In such a case, even if it contains a very small amount of the insecticidal component, it is treated as a pest repellent that does not substantially contain the insecticidal component.
本発明の害虫忌避剤は、殺虫成分を実質的に含有しなくても、本発明の害虫忌避剤における必須成分であるピペリジン誘導体が特定外来アリに対する高い忌避効果を有するため、従来の殺虫成分を含有する忌避剤と同等又はそれ以上の忌避効果を示すものとなる。そして、殺虫剤を実質的に含有しない本発明の害虫忌避剤は、殺虫成分に過敏な消費者にとっても日常的な使用への抵抗が小さいものとなり得る。また、本発明の害虫忌避剤であれば、害虫がディート等の従来の忌避成分に耐性を有することになった場合にも、忌避効果が期待できる。 The pest repellent of the present invention uses the conventional insecticidal component because the piperidine derivative, which is an essential component of the pest repellent of the present invention, has a high repellent effect on specific foreign ants even if it does not substantially contain the insecticidal component. The repellent effect is equal to or higher than that of the contained repellent. And, the pest repellent of the present invention which does not substantially contain an insecticide can have a small resistance to daily use even for consumers who are sensitive to insecticide components. Further, the pest repellent of the present invention can be expected to have a repellent effect even when the pest becomes resistant to conventional repellent components such as DEET.
〔害虫忌避製品〕
本発明の害虫忌避剤は、特別な加工を行わなくても、そのままで特定外来アリを忌避する用途に使用することが可能であるが、使い勝手の良い剤型に調製し、害虫忌避剤を０．０１〜９９ｗ／ｗ％含有する害虫忌避製品として使用することが実用的である。害虫忌避製品の剤型は、代表的には、液状製剤、ジェル状製剤、固形剤が挙げられる。[Pest repellent products]
The pest repellent of the present invention can be used as it is for repelling specific foreign ants without any special processing, but it is prepared into a convenient formulation and the pest repellent is 0. It is practical to use it as a pest repellent product containing 0.01 to 99 w / w%. Dosage forms of pest repellent products typically include liquid formulations, gel formulations and solid formulations.
液状製剤及びジェル状製剤としては、例えば、液剤、乳剤、水溶剤、マイクロエマルジョン、エアゾール、クリーム等が挙げられる。液状製剤及びジェル状製剤は、製剤中の忌避成分、忌避香料成分、忌避効果持続成分などの各種成分の含有量の調整が容易である。そのため、例えば、忌避成分の増量によって忌避効果を強めたり、忌避香料成分の増量によって芳香性の高い製品にするなど、害虫忌避製品の商品特性を変更し易いというメリットを有する。 Examples of liquid preparations and gel preparations include liquid preparations, emulsions, aqueous solvents, microemulsions, aerosols, creams and the like. In liquid preparations and gel preparations, it is easy to adjust the content of various components such as repellent components, repellent fragrance components, and repellent effect lasting components in the preparation. Therefore, for example, increasing the amount of the repellent component enhances the repellent effect, or increasing the amount of the repellent fragrance component makes the product highly aromatic, and has the advantage that the product characteristics of the pest repellent product can be easily changed.
固形剤としては、例えば、粉剤、粒剤、ベイト剤等が挙げられる。固形剤は、液漏れや指先が濡れる心配がないため、取り扱いが容易であるというメリットを有する。固形剤として構成される害虫忌避製品は、例えば、適当な担持体に害虫忌避剤を担持（含浸）させることにより調製することができる。害虫忌避剤を担持体に担持させる際には、必要に応じて、溶剤や界面活性剤等を添加してもよい。担持体としては、木粉、小麦粉等の各種植物質粉末、紙、織布、不織布等の基布、ビスコパール等の多孔質有機成形体、カオリン、タルク、炭酸カルシウム、珪石、珪砂、セラミックス等の無機担持体、ポリエチレン、ポリプロピレン、エチレン／酢酸ビニル共重合体（ＥＶＡ）、エチレン／メタクリル酸メチル共重合体（ＥＭＭＡ）、スチレン系ジブロックポリマー、スチレン系トリブロックポリマー、熱可塑性樹脂エラストマー（ＴＰＥ、ＴＰＯ）等から構成されるフィルム又は成形体、シリコーンゴム等が挙げられる。例えば、担持体が不織布である場合、害虫忌避剤を薬液分注方式や塗布方式によって保持させる方法、あるいはパラフィンワックスとともに包埋させる方法が挙げられる。担持体がフィルム又は成形体である場合、害虫忌避剤を薬液分注方式や塗布方式によって保持させる方法、あるいは害虫忌避剤を溶剤とともに噴霧又は滴下し、フィルム又は成形体に浸透させる方法が挙げられる。担持体がシリコーンゴムである場合、害虫忌避剤を高濃度で含有するシリコーンゴムと無処理のシリコーンゴムとを密閉容器中に投入し、一定時間放置してシリコーンゴム全体に亘って害虫忌避剤の濃度を平均化させる方法が挙げられる。 Examples of the solid preparation include powders, granules, baits and the like. The solid agent has an advantage that it is easy to handle because there is no concern about liquid leakage or getting the fingertips wet. The pest repellent product configured as a solid agent can be prepared, for example, by carrying (impregnating) the pest repellent on an appropriate carrier. When the pest repellent is supported on the carrier, a solvent, a surfactant, or the like may be added, if necessary. The carriers include various vegetable powders such as wood flour and wheat flour, base cloths such as paper, woven cloth and non-woven fabric, porous organic polymers such as biscopearl, kaolin, talc, calcium carbonate, silica stone, silica sand, ceramics and the like. Inorganic carrier, polyethylene, polypropylene, ethylene / vinyl acetate copolymer (EVA), ethylene / methyl methacrylate copolymer (EMMA), styrene-based diblock polymer, styrene-based triblock polymer, thermoplastic resin elastomer (TPE) , TPO) and the like, examples thereof include a film or a molded product, silicone rubber and the like. For example, when the carrier is a non-woven fabric, a method of holding the pest repellent by a chemical dispensing method or a coating method, or a method of embedding with paraffin wax can be mentioned. When the carrier is a film or a molded body, a method of holding the pest repellent by a chemical solution dispensing method or a coating method, or a method of spraying or dropping the pest repellent together with a solvent and permeating the film or the molded body can be mentioned. .. When the carrier is a silicone rubber, the silicone rubber containing a high concentration of the pest repellent and the untreated silicone rubber are put into a closed container and left for a certain period of time to cover the entire silicone rubber. A method of averaging the concentrations can be mentioned.
害虫忌避製品における害虫忌避剤の配合量は、当該害虫忌避製品の用途、使用期間、仕様等に応じて適宜調整されるが、液状製剤又はジェル状製剤の場合は０．０１〜２０ｗ／ｖ％が好ましく、固形剤の場合は０．０１〜１０ｗ／ｗ％が好ましい。例えば、担持体を用いた固形剤の場合、８〜１２時間の使用期間を想定した害虫忌避製品では、一製品あたり害虫忌避剤１０〜５０ｍｇを含有させることが好ましい。１５〜３０日の使用期間を想定した害虫忌避製品では、一製品あたり害虫忌避剤１００〜２０００ｍｇを含有させることが好ましい。 The blending amount of the pest repellent in the pest repellent product is appropriately adjusted according to the use, period of use, specifications, etc. of the pest repellent product, but is 0.01 to 20 w / v% in the case of a liquid preparation or a gel preparation. Is preferable, and in the case of a solid agent, 0.01 to 10 w / w% is preferable. For example, in the case of a solid agent using a carrier, a pest repellent product assuming a usage period of 8 to 12 hours preferably contains 10 to 50 mg of the pest repellent per product. In the pest repellent product assuming a usage period of 15 to 30 days, it is preferable to contain 100 to 2000 mg of the pest repellent per product.
害虫忌避製品を調製するにあたっては、必要に応じて、溶剤、界面活性剤、可溶化剤、ゲル基剤、ゲル化剤、分散剤、安定化剤、ｐＨ調整剤、着色剤等を配合することも可能である。溶剤としては、例えば、水、エタノール、イソプロパノール等の低級アルコール、ケトン系溶剤、エステル系溶剤、ノルマルパラフィンやイソパラフィン等の炭化水素系溶剤等が挙げられる。界面活性剤としては、例えば、ポリオキシエチレン硬化ヒマシ油、ポリオキシエチレン高級アルキルエーテル類（ポリオキシエチレンラウリルエーテル、ポリオキシエチレンオレイルエーテル等）、ポリオキシエチレンアルキルフェニルエーテル類、ポリオキシエチレン高級脂肪酸エステル類、ポリオキシエチレンソルビタン脂肪酸エステル類、ポリオキシエチレングリセリン脂肪酸エステル類、ポリオキシエチレンポリオキシプロピレンアルキルエーテル等の非イオン系界面活性剤、ラウリルアミンオキサイド、ステアリルアミンオキサイド、ラウリル酸アミドプロピルジメチルアミンオキサイド等の高級アルキルアミンオキサイド系界面活性剤が挙げられる。ゲル化剤としては、ポリビニルアルコール、アルギン酸、カラギーナン等が挙げられる。 When preparing a pest repellent product, a solvent, a surfactant, a solubilizer, a gel base, a gelling agent, a dispersant, a stabilizer, a pH adjuster, a coloring agent, etc. should be added as necessary. Is also possible. Examples of the solvent include water, lower alcohols such as ethanol and isopropanol, ketone solvents, ester solvents, hydrocarbon solvents such as normal paraffin and isoparaffin, and the like. Examples of the surfactant include polyoxyethylene hydrogenated castor oil, polyoxyethylene higher alkyl ethers (polyoxyethylene lauryl ether, polyoxyethylene oleyl ether, etc.), polyoxyethylene alkylphenyl ethers, and polyoxyethylene higher fatty acids. Nonionic surfactants such as esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene glycerin fatty acid esters, polyoxyethylene polyoxypropylene alkyl ethers, laurylamine oxide, stearylamine oxide, lauric acid amide propyldimethylamine Examples thereof include higher alkylamine oxide-based surfactants such as oxides. Examples of the gelling agent include polyvinyl alcohol, alginic acid, carrageenan and the like.
本発明の害虫忌避製品は、剤型に応じて様々な場面で使用される。液状製剤として構成された害虫忌避製品は、例えば、スプレー製品として物体や環境に散布して用いられる。ジェル状製剤として構成された害虫忌避製品は、例えば、塗布製品として人体の皮膚に塗布して用いられる。固形剤として構成された害虫忌避製品は、例えば、玄関、台所、トイレ、リビングルーム、寝室、倉庫、車中、ベランダ、ポーチ、庭先、家屋の周囲などに所定量を散布又は載置して用いられる。特に、害虫忌避製品が固形剤である場合は、当該害虫忌避製品を中心として特定外来アリを寄せ付けない三次元バリアが形成されるため、広範囲に亘って忌避効果を及ぼすことができる。成形体やシリコーンゴムに害虫忌避剤を担持して害虫忌避製品を構成したものは、バンドとして足首や靴等に巻装したり、クリップのような固定具で靴等に装着して使用することができる。シールやフィルムに害虫忌避剤を担持して害虫忌避製品を構成したものは、担持体の下面に粘着層を設け、ズボンの下部や靴等に貼付して使用することができる。 The pest repellent product of the present invention is used in various situations depending on the dosage form. The pest repellent product configured as a liquid preparation is used, for example, as a spray product by spraying it on an object or the environment. The pest repellent product configured as a gel preparation is used, for example, by being applied to the skin of a human body as an application product. The pest repellent product composed as a solid agent is used, for example, by spraying or placing a predetermined amount on the entrance, kitchen, toilet, living room, bedroom, warehouse, car, balcony, porch, garden, around the house, etc. Be done. In particular, when the pest repellent product is a solid agent, a three-dimensional barrier that repels specific foreign ants is formed around the pest repellent product, so that the repellent effect can be exerted over a wide range. A pest repellent product that is constructed by carrying a pest repellent on a molded product or silicone rubber should be wrapped around ankles or shoes as a band, or attached to shoes with a fixture such as a clip. Can be done. A pest repellent product formed by supporting a pest repellent on a sticker or a film can be used by providing an adhesive layer on the lower surface of the carrier and attaching it to the lower part of trousers, shoes, or the like.
害虫忌避製品の施用量は、剤型に応じて適宜調整される。液状製剤又はジェル状製剤では、施用量は１０〜５０ｍＬ／ｍ２が好ましい。施用量が１０ｍＬ／ｍ２未満の場合は十分な忌避効果が期待できず、施用量が５０ｍＬ／ｍ２を超える場合はベトツキにより不快感が増す。固形剤では、施用量は１０〜５０ｇ／ｍ２が好ましい。施用量が１０ｇ／ｍ２未満の場合は十分な忌避効果が期待できず、施用量が５０ｇ／ｍ２を超えても忌避効果は殆ど変わらないため経済的ではない。The application rate of the pest repellent product is appropriately adjusted according to the dosage form. For liquid or gel formulations, the dosage is preferably 10-50 mL / m 2 . If the application rate is less than 10 mL / m 2, a sufficient repellent effect cannot be expected, and if the application rate exceeds 50 mL / m 2 , stickiness increases discomfort. For solids, the application rate is preferably 10 to 50 g / m 2 . If the application rate is less than 10 g / m 2, a sufficient repellent effect cannot be expected, and even if the application rate exceeds 50 g / m 2 , the repellent effect is almost unchanged, which is not economical.
次に、本発明の害虫忌避剤、及び害虫忌避製品を用いた実施例について説明する。本発明の害虫忌避剤を種々調製し、これらを用いて在来アリ及び特定外来アリを対象とした効力確認試験を実施した（実施例１〜１９）。また、比較のため、従来の害虫忌避剤についても同様の効力確認試験を実施した（比較例１〜５）。なお、以下の実施例では、各成分の重量単位をｍｇで示しているが、本実施例は任意の倍率でスケールアップが可能である。従って、重量単位「ｍｇ」は「重量部」と読み替えることができる。 Next, examples using the pest repellent agent of the present invention and the pest repellent product will be described. Various pest repellents of the present invention were prepared, and efficacy confirmation tests were conducted on native ants and specific foreign ants using these (Examples 1 to 19). In addition, for comparison, a similar efficacy confirmation test was conducted for conventional pest repellents (Comparative Examples 1 to 5). In the following examples, the weight unit of each component is shown in mg, but in this example, scale-up is possible at an arbitrary magnification. Therefore, the weight unit "mg" can be read as "part by weight".
〔害虫忌避剤の調製〕
下記の表１に示す組成に従って、実施例１〜１９及び比較例１〜５の害虫忌避剤を調製した。[Preparation of pest repellent]
The pest repellents of Examples 1-19 and Comparative Examples 1-5 were prepared according to the compositions shown in Table 1 below.
ここで、害虫忌避成分である表１中のピペリジンａ〜ｆは、前述の式（Ｉ）で表されるピペリジン誘導体において、置換基Ｒが下記の表２に示す官能基である。 Here, the piperidines a to f in Table 1, which are pest repellent components, are functional groups whose substituent R is shown in Table 2 below in the piperidine derivative represented by the above formula (I).
なお、ピペリジンａ（イカリジン）、ピペリジンｂ、及びピペリジンｄは、市場で入手可能な試薬グレードの化合物を使用した。ピペリジンｃ、ピペリジンｅ、及びピペリジンｆについては、下記の手順により本発明者らが合成したものを使用した。 For piperidine a (icaridin), piperidine b, and piperidine d, reagent grade compounds available on the market were used. As piperidine c, piperidine e, and piperidine f, those synthesized by the present inventors by the following procedure were used.
［ピペリジンｃ］
２−（２−ヒドロキシエチル）−ピペリジン（７１５ｍｇ、５．５３ｍｍｏｌ）及びトリエチルアミン（１．０ｍｌ、７．２１ｍｍｏｌ）をトルエン６ｍｌに溶解し、０℃でクロロギ酸ヘキシル（９１０ｍｇ、５．５３ｍｍｏｌ）を加えた。次いで、２０℃で２４時間撹拌した後、反応液に水を注加し、酢酸エチルを用いて有機成分を抽出した。次いで、有機成分が含まれる有機層を、硫酸マグネシウムを用いて乾燥した後、減圧条件下で濃縮し、残渣をシリカゲルカラムクロマトグラフィーに付してピペリジンｃを得た。ピペリジンｃの質量スペクトルを以下に示す。
無色液体：ＭＳ（ＥＩ）ｍ／ｚ［Ｍ］＋：２５７[Piperidine c]
2- (2-Hydroxyethyl) -piperidine (715 mg, 5.53 mmol) and triethylamine (1.0 ml, 7.21 mmol) are dissolved in 6 ml of toluene, and hexyl chloroformate (910 mg, 5.53 mmol) is added at 0 ° C. It was. Then, after stirring at 20 ° C. for 24 hours, water was added to the reaction solution, and the organic component was extracted using ethyl acetate. Next, the organic layer containing the organic component was dried over magnesium sulfate, concentrated under reduced pressure conditions, and the residue was subjected to silica gel column chromatography to obtain piperidine c. The mass spectrum of piperidine c is shown below.
Colorless liquid: MS (EI) m / z [M] + : 257
［ピペリジンｅ］
ピペリジンｃの合成において、クロロギ酸ヘキシルの代わりにクロロギ酸デシルを用いたこと以外は同様の手順により、ピペリジンｅを得た。ピペリジンｅの質量スペクトルを以下に示す。
無色液体：ＭＳ（ＥＩ）ｍ／ｚ［Ｍ］＋：３１３[Piperidine e]
Piperidine e was obtained by the same procedure except that decyl chloroformate was used instead of hexyl chloroformate in the synthesis of piperidine c. The mass spectrum of piperidine e is shown below.
Colorless liquid: MS (EI) m / z [M] + : 313
［ピペリジンｆ］
ピペリジンｃの合成において、クロロギ酸ヘキシルの代わりにｎ−ノナノイルクロリドを用いたこと以外は同様の手順により、ピペリジンｆを得た。ピペリジンｆの質量スペクトルを以下に示す。
無色液体：ＭＳ（ＥＩ）ｍ／ｚ［Ｍ］＋：２６９[Piperidine f]
Piperidine f was obtained by the same procedure except that n-nonanoyl chloride was used instead of hexyl chloroformate in the synthesis of piperidine c. The mass spectrum of piperidine f is shown below.
Colorless liquid: MS (EI) m / z [M] + : 269
〔効力確認試験１〕
実施例１〜１９及び比較例１〜５の害虫忌避剤を夫々アセトン５ｍＬに溶解し、害虫忌避剤の薬液を調製した。夫々の供試薬液０．３ｍＬを、アトマイザーを用いて直径１５ｃｍの濾紙の片側半分に滴下し、風乾した。この場合、乾燥後の濾紙において、例えば、実施例１では害虫忌避剤が濾紙半面あたり３．０ｍｇ含まれることになる。次に、この害虫忌避剤が含まれる濾紙の半面（処理区）と、害虫忌避剤が含まれない濾紙の半面（無処理区）とが重ならないように、濾紙を直径１５ｃｍのガラスシャーレに入れた。そして、ガラスシャーレの内壁にタルクを塗布し、供試虫としてトビイロケアリ（在来アリの一種）又はアカカミアリ（特定外来アリの一種）を夫々３０匹放ち、５分後及び２時間後に処理区及び無処理区に存在するアリの数（虫数）をカウントした。そして、害虫の忌避率を下記の式に従って求めた。
忌避率（％） ＝ （無処理区の虫数−処理区の虫数）／供試虫数 × １００[Effectiveness confirmation test 1]
The pest repellents of Examples 1 to 19 and Comparative Examples 1 to 5 were each dissolved in 5 mL of acetone to prepare a chemical solution of the pest repellent. 0.3 mL of each reagent solution was added dropwise to one half of a filter paper having a diameter of 15 cm using an atomizer, and the mixture was air-dried. In this case, in the dried filter paper, for example, in Example 1, 3.0 mg of the pest repellent is contained per half surface of the filter paper. Next, put the filter paper in a glass petri dish with a diameter of 15 cm so that one side of the filter paper containing the pest repellent (treated area) and the other side of the filter paper not containing the pest repellent (untreated area) do not overlap. It was. Then, talc is applied to the inner wall of the glass petri dish, and 30 black garden ants (a type of native ant) or red ant (a type of specific alien ant) are released as test insects, respectively, and after 5 minutes and 2 hours, the treatment area and none The number of ants (number of insects) present in the treatment area was counted. Then, the pest repellent rate was calculated according to the following formula.
Repellent rate (%) = (Number of insects in untreated area-Number of insects in treated area) / Number of test insects x 100
上記の効力確認試験１を３回実施し、各回の試験でカウントした虫数の平均値を忌避率の計算に使用した。試験結果を以下の表３に示す。 The above efficacy confirmation test 1 was carried out three times, and the average value of the number of insects counted in each test was used for the calculation of the repellent rate. The test results are shown in Table 3 below.
上記の効力確認試験１の結果によれば、前述の式（Ｉ）で表されるピペリジン誘導体を含有する害虫忌避剤を用いると、試験直後（５分後）から特定外来アリの一種であるアカカミアリを寄せ付けない忌避効果が得られた。そして、その高い忌避効果は、２時間経過後も略維持されていた（実施例１〜１９）。なお、在来アリの一種であるトビイロケアリに対しても、アカカミアリと同様の効果が確認された（実施例１〜１９）。特に、式（Ｉ）で表されるピペリジン誘導体において、置換基Ｒが炭素数２〜６のアルコキシ基である化合物の忌避効果が優れており、さらに、置換基Ｒが１−メチルプロポキシ基である化合物（イカリジン）の忌避効果がより優れる結果となった。 According to the result of the above efficacy confirmation test 1, when the pest repellent containing the piperidine derivative represented by the above formula (I) is used, the red ant, which is a kind of specific foreign ant, is used immediately after the test (5 minutes later). A repellent effect was obtained that keeps away. The high repellent effect was substantially maintained even after the lapse of 2 hours (Examples 1 to 19). It should be noted that the same effect as that of the red garden ant was confirmed on the black garden ant, which is a kind of the native ant (Examples 1 to 19). In particular, in the piperidine derivative represented by the formula (I), the repellent effect of the compound in which the substituent R is an alkoxy group having 2 to 6 carbon atoms is excellent, and the substituent R is a 1-methylpropoxy group. The result was that the repellent effect of the compound (Icaridine) was more excellent.
より詳細に考察すると、実施例５〜８及び実施例９〜１９の結果が示すように、害虫忌避成分に加えて、忌避香料成分として、（ａ）総炭素数８〜１６の炭化水素アルデヒド類及び／又は炭化水素ケトン類、及び（ｂ）総炭素数８〜１２のモノテルペン系アルコール類及び／又は芳香族アルコール類の少なくとも一方を含む害虫忌避剤は、害虫忌避成分のみを含む害虫忌避剤と比べて忌避効果が高くなること（相乗効果）が確認された。そして、本実施例によれば、（ａ）の忌避香料成分と（ｂ）の忌避香料成分との配合比率［（ａ）／（ｂ）］が０．１／１〜９／１の範囲において、高い忌避効果を示すことが確認された。さらに、実施例１２と実施例１６との比較、及び実施例１５と実施例１７との比較から、ジプロピレングリコールを配合した場合、害虫忌避成分の忌避効果を持続させる効果があることが認められた。 Considering in more detail, as the results of Examples 5 to 8 and 9 to 19 show, as a repellent fragrance component in addition to the pest repellent component, (a) hydrocarbon aldehydes having a total carbon number of 8 to 16 Pest repellents containing at least one of and / or hydrocarbon ketones and (b) monoterpene alcohols and / or aromatic alcohols having a total carbon number of 8 to 12 are pest repellents containing only pest repellent components. It was confirmed that the repellent effect was higher than that of the above (synergistic effect). Then, according to this example, the blending ratio [(a) / (b)] of the repellent fragrance component (a) and the repellent fragrance component (b) is in the range of 0.1 / 1 to 9/1. , It was confirmed that it shows a high repellent effect. Furthermore, from the comparison between Example 12 and Example 16 and the comparison between Example 15 and Example 17, it was confirmed that the addition of dipropylene glycol has the effect of sustaining the repellent effect of the pest repellent component. It was.
一方、比較例１〜５の結果が示すように、前述の式（Ｉ）で表されるピペリジン誘導体以外の化合物や、人体用忌避剤として汎用されているディートを含む従来の害虫忌避剤は、アリに対する忌避効果が十分であると言えないばかりか、アカカミアリに対する忌避効果は、トビイロケアリに対する忌避効果よりもかなり劣る傾向が認められた。 On the other hand, as shown by the results of Comparative Examples 1 to 5, conventional pest repellents including compounds other than the piperidine derivative represented by the above formula (I) and DEET, which is widely used as a repellent for the human body, are used. Not only was the repellent effect on ants not sufficient, but the repellent effect on red garden ants tended to be considerably inferior to the repellent effect on black garden ant.
〔効力確認試験２〕
実施例１、５〜１４、１８及び比較例１〜５の害虫忌避剤を夫々アセトン５ｍＬに溶解して調製した害虫忌避剤の薬液を使用し、上述の効力確認試験１と同様の手順にて、ヒアリ（特定外来アリの一種）を対象とした効力効果試験２を実施した。ただし、処理区及び無処理区に存在するアリの数（虫数）のカウントは、５分後のみとした。害虫の忌避率の算出方法は、効力確認試験１における算出方法と同様である。試験結果を以下の表４に示す。[Effectiveness confirmation test 2]
Using the pest repellent chemicals prepared by dissolving the pest repellents of Examples 1, 5-14, 18 and Comparative Examples 1 to 5 in 5 mL of acetone, respectively, the procedure was the same as in the efficacy confirmation test 1 described above. , Fire ants (a type of specific foreign ant) were subjected to efficacy test 2. However, the number of ants (number of insects) existing in the treated and untreated plots was counted only after 5 minutes. The calculation method of the pest repellent rate is the same as the calculation method in the efficacy confirmation test 1. The test results are shown in Table 4 below.
上記の効力確認試験２の結果によれば、前述の式（Ｉ）で表されるピペリジン誘導体であって、特に、置換基Ｒが１−メチルプロポキシ基である化合物（イカリジン）を含有する害虫忌避剤を用いると、試験直後（５分後）から特定外来アリの一種であるヒアリについても優れた忌避効果が得られた。 According to the result of the above efficacy confirmation test 2, a pest repellent containing a piperidine derivative represented by the above formula (I), particularly a compound (icaridin) in which the substituent R is a 1-methylpropoxy group. When the agent was used, an excellent repellent effect was obtained for fire ants, which are a type of specific foreign ants, immediately after the test (5 minutes later).
さらに、実施例５〜８の結果が示すように、害虫忌避成分に加えて、忌避香料成分として、（ａ）総炭素数８〜１６の炭化水素アルデヒド類及び／又は炭化水素ケトン類、及び（ｂ）総炭素数８〜１２のモノテルペン系アルコール類及び／又は芳香族アルコール類の少なくとも一方を含む害虫忌避剤は、害虫忌避成分のみを含む害虫忌避剤と比べて忌避効果が高くなること（相乗効果）が確認された。また、実施例５と実施例６との比較、及び実施例７と実施例８との比較から、忌避香料成分としてα−ヘキシルシンナミックアルデヒドを含む害虫忌避剤は、α−ヘキシルシンナミックアルデヒドを含まない害虫忌避剤に対して忌避効果が大幅に向上することが認められた。 Further, as the results of Examples 5 to 8 show, in addition to the pest repellent component, as the repellent fragrance component, (a) hydrocarbon aldehydes and / or hydrocarbon ketones having a total carbon number of 8 to 16 and ( b) A pest repellent containing at least one of a monoterpene alcohol and / or an aromatic alcohol having a total carbon number of 8 to 12 has a higher repellent effect than a pest repellent containing only a pest repellent component ( Synergistic effect) was confirmed. Further, from the comparison between Example 5 and Example 6 and the comparison between Example 7 and Example 8, the pest repellent containing α-hexylcinnamic aldehyde as a repellent fragrance component was α-hexylcinnamic aldehyde. It was found that the repellent effect was significantly improved against the pest repellent that did not contain it.
一方、比較例１〜５の結果が示すように、前述の式（Ｉ）で表されるピペリジン誘導体以外の化合物や、人体用忌避剤として汎用されているディートを含む従来の害虫忌避剤は、ヒアリに対しても忌避効果が劣る結果となった。 On the other hand, as shown by the results of Comparative Examples 1 to 5, conventional pest repellents including compounds other than the piperidine derivative represented by the above formula (I) and DEET, which is widely used as a repellent for the human body, are used. The result was that the repellent effect was inferior to fire ants.
このように、本発明の式（Ｉ）で表されるピペリジン誘導体を含有する害虫忌避剤が、特定外来アリに対して、在来アリと同等又はそれ以上の忌避効果を示したことは、従来のアリ忌避剤では達成できなかった特筆すべき性能であり、本発明の害虫忌避剤の有用性及び実用性が高いことを証明している。 As described above, the pest repellent containing the piperidine derivative represented by the formula (I) of the present invention has conventionally shown a repellent effect on specific foreign ants equal to or higher than that of the conventional ants. It is a remarkable performance that could not be achieved by the ant repellent, and proves that the pest repellent of the present invention is highly useful and practical.
〔害虫忌避製品の構成例〕
次に、本発明の害虫忌避剤を使用した害虫忌避製品の構成例について説明する。[Structure example of pest repellent product]
Next, a configuration example of a pest repellent product using the pest repellent of the present invention will be described.
［スプレー製品（液状製剤）］
害虫忌避成分として前述の式（ＩＩ）で表されるイカリジン８．０ｇ（４．０ｗ／ｖ％）、（ａ）の忌避香料成分としてクミンアルデヒド及び２−ペンチルシクロペンタノン１．０ｇ（０．５ｗ／ｖ％）、（ｂ）の忌避香料成分としてｌ−メントール及び２−フェニルエチルアルコール２．０ｇ（１．０ｗ／ｖ％）、イソプロピルメチルフェノール０．２ｇ（０．１ｗ／ｖ％）、及び柿抽出物由来の消臭成分１．０ｇ（０．５ｗ／ｖ％）を含有する害虫忌避剤を調製した。この害虫忌避剤に、９９％エタノール１１０ｇ（５５ｗ／ｖ％）、及び精製水を加えて全量を２００ｍＬとし、ポンプスプレー容器に充填してスプレータイプの害虫忌避製品（製品Ａ）を構成した。[Spray product (liquid preparation)]
8.0 g (4.0 w / v%) of icaridine represented by the above formula (II) as a pest repellent component, cuminaldehyde and 2-pentylcyclopentanone 1.0 g (0.) as a repellent fragrance component of (a). 5 w / v%), 2.0 g (1.0 w / v%) of l-menthol and 2-phenylethyl alcohol as the repellent fragrance component of (b), 0.2 g (0.1 w / v%) of isopropylmethylphenol, And a pest repellent containing 1.0 g (0.5 w / v%) of a deodorant component derived from cumin extract was prepared. To this pest repellent, 110 g (55 w / v%) of 99% ethanol and purified water were added to make a total volume of 200 mL, which was filled in a pump spray container to form a spray-type pest repellent product (Product A).
上記製品Ａについて、被験者が海辺（ヒアリの生息が報じられていた地域）に出かける前に、上着とズボンに万遍なく（表面に少し湿り気を感じる程度で、およそ２０ｍＬ／１ｍ２）、特に袖口とズボンの下部には入念にスプレーした。着衣した状態で、海辺を約５時間に亘って散策したが、ヒアリ等の特定外来アリだけでなく在来アリや他の害虫にも煩わされることがなく、マダニ類に取り付かれることもなかった。For Product A above, before the subject went to the beach (the area where fire ants were reported to live), evenly on his jacket and trousers (about 20 mL / 1 m 2 with a slight dampness on the surface), especially Carefully sprayed on the cuffs and bottom of the pants. I took a walk along the beach for about 5 hours while wearing clothes, but I was not bothered by not only specific foreign ants such as fire ants but also native ants and other pests, and I was not attached to ticks. ..
［塗布製品（ジェル状製剤）］
害虫忌避成分として前述の式（ＩＩ）で表されるイカリジン３．０ｇ（５．０ｗ／ｗ％）、忌避効果持続成分として１，３−ブチレングリコール３．０ｇ（５．０ｗ／ｗ％）、及び紫外線劣化抑制成分としてパラメトキシ桂皮酸エチルヘキシル０．１２ｇ（０．２ｗ／ｗ％）を含有する害虫忌避剤を調製した。この害虫忌避剤に、ゲル基剤としてカルボキシビニルポリマー０．０９ｇ（０．１５ｗ／ｗ％）、ゲル化剤としてトリエタノールアミン０．０９ｇ（０．１５ｗ／ｗ％）、エタノール２１ｇ（３５ｗ／ｗ％）、及び精製水を加えて全量を６０ｇとし、ジェル吐出容器に充填して無香料のジェルタイプの害虫忌避製品（製品Ｂ）を構成した。[Applied product (gel formulation)]
3.0 g (5.0 w / w%) of icaridin represented by the above formula (II) as a pest repellent component, 3.0 g (5.0 w / w%) of 1,3-butylene glycol as a long-lasting repellent effect component, And a pest repellent containing 0.12 g (0.2 w / w%) of ethylhexyl paramethoxycinnamate as an ultraviolet deterioration suppressing component was prepared. To this pest repellent, 0.09 g (0.15 w / w%) of carboxyvinyl polymer as a gel base, 0.09 g (0.15 w / w%) of triethanolamine as a gelling agent, and 21 g (35 w / w) of ethanol. %) And purified water were added to make a total amount of 60 g, which was filled in a gel discharge container to form an unscented gel-type pest repellent product (Product B).
また、上記の製品Ｂで使用した害虫忌避剤に、（ａ）の忌避香料成分としてジヒドロジャスモン０．６ｇ（１．０ｗ／ｗ％）、及び（ｂ）の忌避香料成分としてｌ−フェニルエチルアルコール及びジヒドロミルセノールを０．６ｇ（１．０ｗ／ｗ％）を別途追加し、その他の成分は製品Ｂで使用した害虫忌避剤と同様に処方して、忌避香料で賦香されたジェルタイプの害虫忌避製品（製品Ｃ）を調製した。 In addition, the pest repellent used in the above product B includes 0.6 g (1.0 w / w%) of dihydrojasmon as the repellent fragrance component of (a) and l-phenylethyl alcohol as the repellent fragrance component of (b). And dihydromilsenol 0.6g (1.0w / w%) is added separately, and other ingredients are formulated in the same way as the pest repellent used in product B, and a gel type flavored with a repellent fragrance. Pest repellent product (Product C) was prepared.
直径が約４ｃｍ、長さが１ｍの棒を２本準備し、一方の棒の中央（５０ｃｍ）付近から上方に製品Ｂを２０ｇ／ｍ２の塗布量で塗布した。また、他方の棒についても同様に製品Ｃを同じ塗布量で塗布した。ヒアリが頻繁に出入りする巣に両方の棒を突き刺し、ヒアリの行動を観察したところ、いずれの棒についてもヒアリが棒の中央付近まで這い上がった後に引き返す行動が見られた。そして、このヒアリの行動（巣への引き返し）は、製品Ｃの方が製品Ｂよりも幾分速やかであった。このように、イカリジンはヒアリ等の特定外来アリに対して高い忌避効果を示すことが示され、さらに、（ａ）の忌避香料成分と（ｂ）の忌避香料成分とをイカリジンと併用することにより、特定外来アリに対する忌避効果が増強されること（相乗効果）が実証された。Two rods having a diameter of about 4 cm and a length of 1 m were prepared, and product B was applied at a coating amount of 20 g / m 2 from the vicinity of the center (50 cm) of one rod upward. In addition, the product C was similarly applied to the other rod in the same amount. Both rods were pierced into the nests where fire ants frequently enter and exit, and fire ant behavior was observed. For both rods, fire ants crawled up to near the center of the rod and then turned back. The fire ant's behavior (returning to the nest) was somewhat faster in product C than in product B. As described above, icaridin has been shown to show a high repellent effect on specific foreign ants such as fire ants, and further, by using the repellent fragrance component (a) and the repellent fragrance component (b) in combination with icaridin. It was demonstrated that the repellent effect on specific foreign ants is enhanced (synergistic effect).
本発明の害虫忌避剤、及び害虫忌避製品は、特に、特定外来アリを忌避、防除する目的において有用なものであり、さらに、家庭用忌避剤又は忌避製品としてだけでなく、業務用忌避剤又は忌避製品としても利用可能である。 The pest repellent and pest repellent product of the present invention are particularly useful for the purpose of repelling and controlling specific foreign ants, and further, not only as a household repellent or repellent product, but also as a commercial repellent or It can also be used as a repellent product.
Claims (9)
（ａ）総炭素数８〜１６の炭化水素アルデヒド類及び／又は炭化水素ケトン類
（ｂ）総炭素数８〜１２のモノテルペン系アルコール類及び／又は芳香族アルコール類の少なくとも一方をさらに含有する請求項１〜３の何れか一項に記載の害虫忌避剤。As the repellent fragrance component, the following (a) and (b):
(A) Hydrocarbon aldehydes and / or hydrocarbon ketones having a total carbon number of 8 to 16 (b) Monoterpene alcohols and / or aromatic alcohols having a total carbon number of 8 to 12 are further contained. The pest repellent according to any one of claims 1 to 3.
前記（ｂ）の忌避香料成分は、リナロール、デヒドロリナロール、ジヒドロミルセノール、ゲラニオール、ネロール、シトロネロール、メントール、テルピネオール、テルピネン−４−オール、イソプレゴール、ボルネオール、１−フェニルエチルアルコール、２−フェニルエチルアルコール、シンナミックアルコール、チモール、及びオイゲノールからなる群から選択される少なくとも一つである請求項４に記載の害虫忌避剤。The repellent fragrance component of (a) is decanal, undecalal, dodecanal, 2-methylundecanal, tridecanal, 10-undecaneal, citroneral, citral, neral, phenylacetaldehyde, synamic aldehyde, α-amylcinnamic aldehyde, α-Hexyl cinnamic aldehyde, lilial, peryl aldehyde, trivertal, cumin aldehyde, heliotropin, tridecanon, l-carboxylic, menton, pregon, cis-jasmon, dihydrojasmon, α-damascon, β-damascon, δ-damascon, α At least one selected from the group consisting of −ionone, β-ionone, 2-pentylcyclopentanone, 2-hexylcyclopentanone, 2-heptylcyclopentanone, methylbenzylketone, and methylstyrylketone.
The repellent fragrance component of (b) is linalool, dehydrolinalol, dihydromilsenol, geraniol, nerol, citronellol, menthol, terpineol, terpine-4-ol, isopregol, borneol, 1-phenylethyl alcohol, 2-phenylethyl. The pest repellent according to claim 4, which is at least one selected from the group consisting of alcohol, synamic alcohol, timol, and eugenol.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004503569A (en) * | 2000-07-14 | 2004-02-05 | バイエル アクチェンゲゼルシャフト | Composition for repelling crawling insects |
| JP2014125451A (en) * | 2012-12-26 | 2014-07-07 | Earth Chemical Co Ltd | Avoidance method of gastropodous pests |
| JP2017114770A (en) * | 2015-12-21 | 2017-06-29 | 国立大学法人 東京大学 | Pest repellent |
| JP2017149653A (en) * | 2016-02-22 | 2017-08-31 | 日油株式会社 | Pest repellent composition |
| WO2017170362A1 (en) * | 2016-03-31 | 2017-10-05 | 大日本除蟲菊株式会社 | Flying pest insect repelling product and flying pest insect repelling method |
| JP2019034906A (en) * | 2017-08-18 | 2019-03-07 | 大日本除蟲菊株式会社 | Ant repellent composition, and ant repellent product using the same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63174982A (en) * | 1987-01-16 | 1988-07-19 | Nitto Electric Ind Co Ltd | Novel optically active epoxy ester |
| JP3848412B2 (en) | 1996-10-31 | 2006-11-22 | フマキラー株式会社 | Ant repellent |
| CA2536696A1 (en) * | 2003-09-05 | 2005-03-24 | Poseidon Ocean Sciences, Inc. | Menthol propyleneglycol-carbonate and analogs thereof as insect pest repellents. |
| US8404260B2 (en) * | 2008-04-02 | 2013-03-26 | Bayer Cropscience Lp | Synergistic pesticide compositions |
| JP2010195766A (en) | 2009-01-29 | 2010-09-09 | Sds Biotech Corp | Method for controlling pyrethroid-resistant insect pest |
| WO2013136073A1 (en) * | 2012-03-13 | 2013-09-19 | Redx Pharma Limited | Agricultural chemicals |
| TWI662895B (en) * | 2015-11-30 | 2019-06-21 | 日商大日本除蟲菊股份有限公司 | Insect pest repellent composition in powder form, and method for producing same |
| MY199207A (en) * | 2016-07-15 | 2023-10-19 | Lec Kk | Pest repellent composition, and method for repelling pests |
| JP7037321B2 (en) * | 2017-10-04 | 2022-03-16 | 大日本除蟲菊株式会社 | Ant control agent |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004503569A (en) * | 2000-07-14 | 2004-02-05 | バイエル アクチェンゲゼルシャフト | Composition for repelling crawling insects |
| JP2014125451A (en) * | 2012-12-26 | 2014-07-07 | Earth Chemical Co Ltd | Avoidance method of gastropodous pests |
| JP2017114770A (en) * | 2015-12-21 | 2017-06-29 | 国立大学法人 東京大学 | Pest repellent |
| JP2017149653A (en) * | 2016-02-22 | 2017-08-31 | 日油株式会社 | Pest repellent composition |
| WO2017170362A1 (en) * | 2016-03-31 | 2017-10-05 | 大日本除蟲菊株式会社 | Flying pest insect repelling product and flying pest insect repelling method |
| JP2019034906A (en) * | 2017-08-18 | 2019-03-07 | 大日本除蟲菊株式会社 | Ant repellent composition, and ant repellent product using the same |
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