JPWO2019191327A5 - - Google Patents

Info

Publication number

JPWO2019191327A5

JPWO2019191327A5 JP2020552805A JP2020552805A JPWO2019191327A5 JP WO2019191327 A5 JPWO2019191327 A5 JP WO2019191327A5 JP 2020552805 A JP2020552805 A JP 2020552805A JP 2020552805 A JP2020552805 A JP 2020552805A JP WO2019191327 A5 JPWO2019191327 A5 JP WO2019191327A5

Authority

JP

Japan

Prior art keywords

alkylene

alkyl

haloalkyl

alkoxy

conr

Prior art date

2022-04-01

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 125000000623 heterocyclic group Chemical group 0.000 claims 22
• 229910052736 halogen Inorganic materials 0.000 claims 18
• 150000002367 halogens Chemical class 0.000 claims 18
• 125000000217 alkyl group Chemical group 0.000 claims 17
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 17
• 229910052760 oxygen Inorganic materials 0.000 claims 12
• 229910052757 nitrogen Inorganic materials 0.000 claims 10
• 150000001875 compounds Chemical class 0.000 claims 9
• 125000002947 alkylene group Chemical group 0.000 claims 8
• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 8
• 125000001072 heteroaryl group Chemical group 0.000 claims 8
• 125000000753 cycloalkyl group Chemical group 0.000 claims 7
• 125000001188 haloalkyl group Chemical group 0.000 claims 6
• 125000005842 heteroatom Chemical group 0.000 claims 6
• 229910052717 sulfur Inorganic materials 0.000 claims 6
• 125000003118 aryl group Chemical group 0.000 claims 5
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 5
• 125000004433 nitrogen atom Chemical group N* 0.000 claims 5
• 125000006413 ring segment Chemical group 0.000 claims 5
• 150000003839 salts Chemical class 0.000 claims 5
• 125000003107 substituted aryl group Chemical group 0.000 claims 5
• 125000003545 alkoxy group Chemical group 0.000 claims 4
• 125000004093 cyano group Chemical group *C#N 0.000 claims 4
• 229910052739 hydrogen Inorganic materials 0.000 claims 4
• 239000001257 hydrogen Substances 0.000 claims 4
• 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 4
• 125000001037 p-tolyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])[H] 0.000 claims 4
• 125000003709 fluoroalkyl group Chemical group 0.000 claims 3
• 125000002393 azetidinyl group Chemical group 0.000 claims 2
• 125000004069 aziridinyl group Chemical group 0.000 claims 2
• 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 2
• 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 2
• 125000004438 haloalkoxy group Chemical group 0.000 claims 2
• 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
• 125000001313 C5-C10 heteroaryl group Chemical group 0.000 claims 1
• 208000019888 Circadian rhythm sleep disease Diseases 0.000 claims 1
• 208000001456 Jet Lag Syndrome Diseases 0.000 claims 1
• 238000009825 accumulation Methods 0.000 claims 1
• 210000000577 adipose tissue Anatomy 0.000 claims 1
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
• 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
• 230000037213 diet Effects 0.000 claims 1
• 235000005911 diet Nutrition 0.000 claims 1
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
• 238000002695 general anesthesia Methods 0.000 claims 1
• 208000033915 jet lag type circadian rhythm sleep disease Diseases 0.000 claims 1
• 201000003631 narcolepsy Diseases 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 238000011084 recovery Methods 0.000 claims 1
• 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1