JPWO2019031614A1 - ヘミアスタリン誘導体を含む抗体薬物複合体 - Google Patents

ヘミアスタリン誘導体を含む抗体薬物複合体 Download PDF

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Publication number
JPWO2019031614A1
JPWO2019031614A1 JP2019535732A JP2019535732A JPWO2019031614A1 JP WO2019031614 A1 JPWO2019031614 A1 JP WO2019031614A1 JP 2019535732 A JP2019535732 A JP 2019535732A JP 2019535732 A JP2019535732 A JP 2019535732A JP WO2019031614 A1 JPWO2019031614 A1 JP WO2019031614A1
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formula
group
compound
antibody
integer
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JPWO2019031614A5 (https=
Inventor
坂　仁志
仁志 坂
篤志 諏訪
篤志 諏訪
洋輔 高梨
洋輔 高梨
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Sumitomo Pharma Co Ltd
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Sumitomo Dainippon Pharma Co Ltd
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Publication of JPWO2019031614A5 publication Critical patent/JPWO2019031614A5/ja
Priority to JP2022199206A priority Critical patent/JP7235929B1/ja
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    • C—CHEMISTRY; METALLURGY
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    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
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  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
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  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
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  • Oncology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2019535732A 2017-08-10 2018-08-10 ヘミアスタリン誘導体を含む抗体薬物複合体 Withdrawn JPWO2019031614A1 (ja)

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WO2020166592A1 (ja) * 2019-02-13 2020-08-20 大日本住友製薬株式会社 ヘミアスタリン誘導体とその抗体薬物複合体
JP7432531B2 (ja) * 2019-02-13 2024-02-16 住友ファーマ株式会社 システイン残基を有するヘミアスタリン誘導体
JP7437328B2 (ja) * 2019-02-13 2024-02-22 住友ファーマ株式会社 多能性幹細胞の除去剤

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