JPWO2015107774A1 - 皮膚上層部への薬液注入用注射器 - Google Patents
皮膚上層部への薬液注入用注射器 Download PDFInfo
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- JPWO2015107774A1 JPWO2015107774A1 JP2015557724A JP2015557724A JPWO2015107774A1 JP WO2015107774 A1 JPWO2015107774 A1 JP WO2015107774A1 JP 2015557724 A JP2015557724 A JP 2015557724A JP 2015557724 A JP2015557724 A JP 2015557724A JP WO2015107774 A1 JPWO2015107774 A1 JP WO2015107774A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3286—Needle tip design, e.g. for improved penetration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3107—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle for needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3293—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
図1〜3に示す本発明の皮膚上層部への薬液注入用注射器を、試作した。その注射針は、表1に示すような針ハブからの突出針長L1と軸方向における刃面の刃面長L2とを、有するものである。注射針は、0.5mmのシリコーンゴムシートに10mm/分で穿刺した際の穿刺抵抗を荷重変動曲線の最大値で0.15N以下とする33ゲージのものである。薬液として生理食塩水を用いた。
Claims (9)
- 針先から針基端に連通する針穴が設けられ前記針先に刃面を有する注射針と、
先端部と基端部とを有し、前記先端部に前記注射針を保持する針ハブとからなり、
前記針ハブには針先側端面を有し、前記針先は前記針先側端面から突出するものであって、
前記針先側端面からの前記針先の突出針長を1.15mm±0.1mmとし、前記注射針の軸心に沿った前記刃面の刃面長を0.60mm±0.15mmとすることを特徴とする皮膚上層部への薬液注入用注射器。 - 前記針ハブが、前記注射針と同軸に設けられ、かつ前記針先及び前記刃面を突出させて前記突出針長を調整している調整部を有し、前記針先側端面は前記調整部の先端に設けられていることを特徴とする請求項1に記載の皮膚上層部への薬液注入用注射器。
- 前記針ハブが、前記調整部と同軸に設けられ、かつ前記調整部を取り囲みつつ離間した筒状の安定部を有していることを特徴とする請求項2に記載の皮膚上層部への薬液注入用注射器。
- 前記皮膚上層部がヒトの真皮層であり、前記針先側での前記針穴の開口が前記真皮層の表皮寄りの注入すべき標的部位に到るように、前記突出針長と前記刃面長とにより調整されていることを特徴とする請求項1から3のいずれかに記載の皮膚上層部への薬液注入用注射器。
- 内部には筒基端から挿入されたガスケットによって薬液を封止して収容するとともに、筒先端には前記薬液を排出する薬液排出管が設けられた外筒を有し、
前記外筒は前記薬液排出管から前記針ハブの基端に接続されていることを特徴とする請求項1から4のいずれかに記載の皮膚上層部への薬液注入用注射器。 - 先端と基端とを有し、かつ前記先端から前記基端に連通する嵌入孔が設けられた嵌入筒を有し、前記嵌入孔は、前記先端には前記針ハブの前記基端部、前記基端には前記外筒の前記薬液排出管が嵌入されていることを特徴とする請求項5に記載の皮膚上層部への薬液注入用注射器。
- 前記針ハブの前記基端部側に載置され前記注射針が挿通された弾性体を、有することを特徴とする請求項1から6のいずれかに記載の皮膚上層部への薬液注入用注射器。
- 前記薬液が生物製剤であって、前記外筒がプレフィルドシリンジであることを特徴とする請求項5に記載の皮膚上層部への薬液注入用注射器。
- 3〜35Nで押圧されて前記皮膚上層部に前記薬液を注入させるプランジャが、前記ガスケットに接続されていることを特徴とする請求項5に記載の皮膚上層部への薬液注入用注射器。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014005888 | 2014-01-16 | ||
JP2014005888 | 2014-01-16 | ||
PCT/JP2014/080950 WO2015107774A1 (ja) | 2014-01-16 | 2014-11-21 | 皮膚上層部への薬液注入用注射器 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPWO2015107774A1 true JPWO2015107774A1 (ja) | 2017-03-23 |
Family
ID=53542678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2015557724A Pending JPWO2015107774A1 (ja) | 2014-01-16 | 2014-11-21 | 皮膚上層部への薬液注入用注射器 |
Country Status (4)
Country | Link |
---|---|
US (1) | US10413681B2 (ja) |
EP (1) | EP3095476A4 (ja) |
JP (1) | JPWO2015107774A1 (ja) |
WO (1) | WO2015107774A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6625566B2 (ja) * | 2015-01-20 | 2019-12-25 | テルモ株式会社 | 注射針組立体及びそれを備えた皮膚上層部への薬液注入用注射器 |
US11351299B2 (en) | 2019-03-15 | 2022-06-07 | Chiesi Farmaceutici S.P.A. | System comprising a pre-fillable syringe and a package for the pre-fillable syringe |
WO2020187660A1 (en) * | 2019-03-15 | 2020-09-24 | Chiesi Farmaceutici S.P.A. | System comprising a pre-fillable syringe and a package for the pre-fillable syringe |
USD940860S1 (en) | 2019-03-15 | 2022-01-11 | Chiesi Farmaceutici S.P.A. | Administration kit and associated components thereof |
US11369733B2 (en) | 2019-03-15 | 2022-06-28 | Chiesi Farmaceutici S.P.A. | System comprising a pre-fillable syringe and a package for the pre-fillable syringe |
USD935608S1 (en) | 2019-03-15 | 2021-11-09 | Chiesi Farmaceutici S.P.A. | Plunger for syringe |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005537893A (ja) * | 2002-09-10 | 2005-12-15 | ベクトン・ディキンソン・アンド・カンパニー | 表皮への物質の送出方法および装置 |
JP2009516572A (ja) * | 2005-11-21 | 2009-04-23 | ベクトン・ディキンソン・アンド・カンパニー | 皮内送出装置 |
JP2012508058A (ja) * | 2008-11-07 | 2012-04-05 | ベクトン・ディキンソン・アンド・カンパニー | 薬剤の注射を容易にするシリンジ筐体 |
WO2012153563A1 (ja) * | 2011-05-10 | 2012-11-15 | テルモ株式会社 | 注射針組立体及び薬剤注射装置 |
WO2013072455A1 (de) * | 2011-11-16 | 2013-05-23 | Lts Lohmann Therapie-Systeme Ag | Zylinder-kolben-einheit mit kurzkanüle |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI449551B (zh) * | 2009-01-30 | 2014-08-21 | Terumo Corp | 注射針組合體以及藥劑注射裝置 |
JP5719522B2 (ja) * | 2010-03-31 | 2015-05-20 | テルモ株式会社 | 薬剤投与器具及び薬剤注射装置 |
US20120124762A1 (en) * | 2010-11-22 | 2012-05-24 | Mark Caligaris | Deordorizing member with cleaning ability and method |
-
2014
- 2014-11-21 WO PCT/JP2014/080950 patent/WO2015107774A1/ja active Application Filing
- 2014-11-21 JP JP2015557724A patent/JPWO2015107774A1/ja active Pending
- 2014-11-21 EP EP14879228.6A patent/EP3095476A4/en not_active Withdrawn
-
2016
- 2016-07-15 US US15/211,741 patent/US10413681B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005537893A (ja) * | 2002-09-10 | 2005-12-15 | ベクトン・ディキンソン・アンド・カンパニー | 表皮への物質の送出方法および装置 |
JP2009516572A (ja) * | 2005-11-21 | 2009-04-23 | ベクトン・ディキンソン・アンド・カンパニー | 皮内送出装置 |
JP2012508058A (ja) * | 2008-11-07 | 2012-04-05 | ベクトン・ディキンソン・アンド・カンパニー | 薬剤の注射を容易にするシリンジ筐体 |
WO2012153563A1 (ja) * | 2011-05-10 | 2012-11-15 | テルモ株式会社 | 注射針組立体及び薬剤注射装置 |
WO2013072455A1 (de) * | 2011-11-16 | 2013-05-23 | Lts Lohmann Therapie-Systeme Ag | Zylinder-kolben-einheit mit kurzkanüle |
Also Published As
Publication number | Publication date |
---|---|
EP3095476A4 (en) | 2017-09-27 |
WO2015107774A1 (ja) | 2015-07-23 |
US20160317761A1 (en) | 2016-11-03 |
US10413681B2 (en) | 2019-09-17 |
EP3095476A1 (en) | 2016-11-23 |
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