JPWO2002046154A1 - ペルオキシソーム増殖剤応答性受容体δの活性化剤 - Google Patents
ペルオキシソーム増殖剤応答性受容体δの活性化剤 Download PDFInfo
- Publication number
- JPWO2002046154A1 JPWO2002046154A1 JP2002547893A JP2002547893A JPWO2002046154A1 JP WO2002046154 A1 JPWO2002046154 A1 JP WO2002046154A1 JP 2002547893 A JP2002547893 A JP 2002547893A JP 2002547893 A JP2002547893 A JP 2002547893A JP WO2002046154 A1 JPWO2002046154 A1 JP WO2002046154A1
- Authority
- JP
- Japan
- Prior art keywords
- group
- carbon atoms
- alkyl
- alkyl group
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000369890 | 2000-12-05 | ||
JP2000369890 | 2000-12-05 | ||
PCT/JP2001/010576 WO2002046154A1 (fr) | 2000-12-05 | 2001-12-04 | Activateurs $g(d) de recepteur active par un proliferateur du peroxysome |
Publications (1)
Publication Number | Publication Date |
---|---|
JPWO2002046154A1 true JPWO2002046154A1 (ja) | 2004-04-08 |
Family
ID=18839860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002547893A Pending JPWO2002046154A1 (ja) | 2000-12-05 | 2001-12-04 | ペルオキシソーム増殖剤応答性受容体δの活性化剤 |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPWO2002046154A1 (fr) |
AU (1) | AU2002224138A1 (fr) |
WO (1) | WO2002046154A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002243778A1 (en) * | 2001-02-02 | 2002-09-19 | Smithkline Beecham Corporation | Treatment of ppar mediated diseases |
EP2305352A1 (fr) | 2004-04-02 | 2011-04-06 | Merck Sharp & Dohme Corp. | Inhibiteurs de la 5-alpha-reductase pour le traitement d'hommes aux troubles métaboliques et anthropométriques |
WO2005105736A1 (fr) | 2004-05-05 | 2005-11-10 | Novo Nordisk A/S | Nouveaux composes, leur preparation et leur utilisation |
ES2352085T3 (es) | 2004-05-05 | 2011-02-15 | High Point Pharmaceuticals, Llc | Nuevos compuestos, su preparación y uso. |
FR2879194B1 (fr) * | 2004-12-14 | 2007-01-19 | Galderma Res & Dev | Nouveaux composes bi-aromatiques modulateurs des recepteurs de type ppar, leur procede de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques |
FR2880889B1 (fr) * | 2005-01-14 | 2007-04-06 | Merck Sante Soc Par Actions Si | Derives de l'acide 1h-indole-3-carboxylique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique |
BRPI0612730A2 (pt) | 2005-06-30 | 2010-11-30 | Novo Nordisk As | compostos, suas preparações e uso |
US7943613B2 (en) | 2005-12-22 | 2011-05-17 | High Point Pharmaceuticals, Llc | Compounds, their preparation and use |
WO2007101864A2 (fr) | 2006-03-09 | 2007-09-13 | High Point Pharmaceuticals, Llc | Nouveaux composés, leur préparation et utilisation |
WO2010045361A1 (fr) | 2008-10-17 | 2010-04-22 | Metabolex, Inc. | Procédés de réduction de petites particules denses de ldl |
CN102264228A (zh) | 2008-10-22 | 2011-11-30 | 默沙东公司 | 用于抗糖尿病药的新的环状苯并咪唑衍生物 |
AU2009309037A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
AU2011218830B2 (en) | 2010-02-25 | 2014-07-24 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
WO2012027331A1 (fr) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions et procédés pour traiter ou prévenir un syndrome métabolique et des maladies et troubles associés |
ES2652662T3 (es) | 2011-02-25 | 2018-02-05 | Merck Sharp & Dohme Corp. | Novedosos derivados de azabencimidazol cíclicos útiles como agentes antidiabéticos |
AU2013296470B2 (en) | 2012-08-02 | 2016-03-17 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
MX2015010935A (es) | 2013-02-22 | 2015-10-29 | Merck Sharp & Dohme | Compuestos biciclicos antidiabeticos. |
WO2014139388A1 (fr) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Nouveaux dérivés d'indole utiles en tant qu'agents antidiabétiques |
CA2923422C (fr) | 2013-09-09 | 2021-09-07 | Vtv Therapeutics Llc | Utilisation d'un agoniste de ppar-delta pour le traitement d'une amyotrophie |
WO2015051496A1 (fr) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Composés tricycliques antidiabétiques |
WO2018106518A1 (fr) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Composés hétérocycliques antidiabétiques |
US10968232B2 (en) | 2016-12-20 | 2021-04-06 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
WO2023147309A1 (fr) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Utilisation d'agonistes ppar-delta dans le traitement d'une maladie |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE116971T1 (de) * | 1990-08-23 | 1995-01-15 | Pfizer | Hypoglykämische hydroxyharnstoffderivate. |
WO1997028149A1 (fr) * | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Procede pour augmenter les niveaux de cholesterol hdl |
AU719146B2 (en) * | 1996-02-02 | 2000-05-04 | Merck & Co., Inc. | Antidiabetic agents |
-
2001
- 2001-12-04 AU AU2002224138A patent/AU2002224138A1/en not_active Abandoned
- 2001-12-04 WO PCT/JP2001/010576 patent/WO2002046154A1/fr active Application Filing
- 2001-12-04 JP JP2002547893A patent/JPWO2002046154A1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2002046154A1 (fr) | 2002-06-13 |
AU2002224138A1 (en) | 2002-06-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPWO2002046154A1 (ja) | ペルオキシソーム増殖剤応答性受容体δの活性化剤 | |
JP4157381B2 (ja) | ペルオキシソーム増殖剤応答性受容体の活性化剤 | |
JP4276074B2 (ja) | ペルオキシソーム増殖剤応答性受容体δの活性化剤 | |
JP4790969B2 (ja) | ペルオキシソーム増殖剤応答性受容体δの活性化剤 | |
JP3997491B2 (ja) | カルバゾール誘導体、その溶媒和物、又は薬学的に許容されるその塩 | |
US6583166B1 (en) | Triazole compounds with dopamine-D3-receptor affinity | |
JP2002507999A (ja) | トリアゾール化合物およびドーパミン−d▲下3▼−リガンドとしてのその使用 | |
US8648208B2 (en) | Activating agent for peroxisome proliferator activated receptor | |
US5606073A (en) | Diazole-propenoic acid compounds | |
JP2001354671A (ja) | ペルオキシソーム増殖剤応答性受容体δの活性化剤 | |
JPWO2002046176A1 (ja) | ペルオキシソーム増殖剤応答性受容体の活性化剤 | |
JPH11512701A (ja) | 選択的なβ▲下3▼アドレナリン作動性アゴニスト | |
JPWO2006059744A1 (ja) | ペルオキシソーム増殖剤活性化受容体δの活性化剤 | |
RU2256661C2 (ru) | Производные тетрагидроизохинолина и их соли и фармацевтическая композиция на их основе | |
BRPI0617364A2 (pt) | compostos heterocÍclicos como inibidores de pstat3/il-6 | |
JP2009514816A (ja) | 新規ベータ−アゴニスト、それらの調製方法及び薬物としてのそれらの使用 | |
KR20070121028A (ko) | 치환된 아미노알킬- 및 아미도알킬-벤조피란 유도체 | |
JP2875557B2 (ja) | ヘテロ環置換アルコキシクマリン、その製造方法およびこれを含有する治療剤 | |
KR101662592B1 (ko) | 퍼옥시좀 증식체-활성화 수용체 하위유형 델타에 대한 흥분 효과를 가진 화합물, 이의 제조방법 및 이의 용도 | |
RU2287529C2 (ru) | Новые гетероциклические производные и их медицинское использование | |
WO2020192650A1 (fr) | Procédé de préparation de composé amide et son application dans le domaine de la médecine | |
KR20080065674A (ko) | 신규한 인돌 함유 베타 효능제, 이의 제조 방법 및약제로서의 이의 용도 | |
WO1993020065A1 (fr) | Nouveau derive d'imidazole, son utilisation pharmaceutique, et intermediaire associe | |
JP2007099641A (ja) | インドールキノキサリン類化合物、その製造方法およびそれを用いた医薬組成物 | |
JP2002322163A (ja) | ピペラジン誘導体 |