JPS6416724A - Stable and injectable vinca dimer salt solution - Google Patents

Stable and injectable vinca dimer salt solution

Info

Publication number
JPS6416724A
JPS6416724A JP63056522A JP5652288A JPS6416724A JP S6416724 A JPS6416724 A JP S6416724A JP 63056522 A JP63056522 A JP 63056522A JP 5652288 A JP5652288 A JP 5652288A JP S6416724 A JPS6416724 A JP S6416724A
Authority
JP
Japan
Prior art keywords
solution
ethylenediaminetetraacetate
vinca dimer
aqueous solution
injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP63056522A
Other languages
English (en)
Other versions
JPH0525857B2 (ja
Inventor
Kasan Rodonii
Seifu Maikeru
Erin Haimu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of JPS6416724A publication Critical patent/JPS6416724A/ja
Publication of JPH0525857B2 publication Critical patent/JPH0525857B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP63056522A 1987-07-06 1988-03-11 Stable and injectable vinca dimer salt solution Granted JPS6416724A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL83086A IL83086A (en) 1987-07-06 1987-07-06 Stable,injectable solutions of vincristine salts

Publications (2)

Publication Number Publication Date
JPS6416724A true JPS6416724A (en) 1989-01-20
JPH0525857B2 JPH0525857B2 (ja) 1993-04-14

Family

ID=11057953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63056522A Granted JPS6416724A (en) 1987-07-06 1988-03-11 Stable and injectable vinca dimer salt solution

Country Status (8)

Country Link
US (1) US4883805A (ja)
EP (1) EP0298192B1 (ja)
JP (1) JPS6416724A (ja)
AT (1) ATE65401T1 (ja)
CA (1) CA1303992C (ja)
DE (1) DE3863859D1 (ja)
ES (1) ES2028917T3 (ja)
IL (1) IL83086A (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007515461A (ja) * 2003-12-23 2007-06-14 ピエール、ファーブル、メディカマン 非経口投与を目的とするビンフルニンの医薬組成物、その調製方法およびその使用
JP2015127300A (ja) * 2013-12-27 2015-07-09 富士フイルム株式会社 注射液製剤及びその製造方法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204995B (en) * 1989-11-07 1992-03-30 Richter Gedeon Vegyeszet Process for producing pharmaceutical composition comprising alkaloid with bis-indole skeleton, with antitumour activity and suitable fr parenteral purposes
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
DE19818802A1 (de) * 1998-04-27 1999-10-28 Dresden Arzneimittel Stabile Mitoxantron-Lösungen
AU2001256714A1 (en) 2000-05-15 2001-11-26 Kissei Pharmaceutical Co. Ltd. Water-based liquid preparation
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
CN104383542B (zh) 2003-04-08 2017-09-26 普罗热尼奇制药公司 包含甲基纳曲酮的药物配方
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
US7923037B2 (en) * 2006-10-05 2011-04-12 Ikaria, Inc. Liquid chalcogenide compositions and methods of manufacturing and using the same
WO2017021981A1 (en) * 2015-08-01 2017-02-09 Sun Pharmaceutical Industries Ltd. Dosage form of vinca alkaloid drug
CN114699369A (zh) * 2022-05-19 2022-07-05 青岛农业大学 一种盐酸溴己新注射液及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3248291A (en) * 1963-08-19 1966-04-26 Hoffmann La Roche Stabilized thioxanthene derivatives and method of using the same
GB1254057A (en) * 1969-04-24 1971-11-17 Louisette Olivier Improvements in or relating to therapeutical composition containing vincamine
GB2020180B (en) * 1978-05-08 1982-08-25 Nelson Res & Dev Ophthalmic compositions containingcolchicine or vinblastinr
US4619935A (en) * 1983-03-17 1986-10-28 Eli Lilly And Company Stable oncolytic formulations
US4708962A (en) * 1984-12-17 1987-11-24 Harbor Branch Oceanographic Institution, Inc. Antiviral and antitumor cyclohexadienone compositions
US4707498A (en) * 1986-01-14 1987-11-17 Merrell Dow Pharmaceuticals Inc. Fluorinated diaminoalkyne derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007515461A (ja) * 2003-12-23 2007-06-14 ピエール、ファーブル、メディカマン 非経口投与を目的とするビンフルニンの医薬組成物、その調製方法およびその使用
JP2012102120A (ja) * 2003-12-23 2012-05-31 Pierre Fabre Medicament 非経口投与を目的とするビンフルニンの医薬組成物、その調製方法およびその使用
JP2015127300A (ja) * 2013-12-27 2015-07-09 富士フイルム株式会社 注射液製剤及びその製造方法

Also Published As

Publication number Publication date
IL83086A (en) 1991-03-10
DE3863859D1 (de) 1991-08-29
AU604094B2 (en) 1990-12-06
EP0298192B1 (en) 1991-07-24
CA1303992C (en) 1992-06-23
ATE65401T1 (de) 1991-08-15
ES2028917T3 (es) 1992-07-16
AU1257888A (en) 1989-01-12
US4883805A (en) 1989-11-28
EP0298192A1 (en) 1989-01-11
JPH0525857B2 (ja) 1993-04-14
IL83086A0 (en) 1987-12-31

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