ATE410182T1 - Formulierungen für amylin peptidagonisten mit insulin - Google Patents
Formulierungen für amylin peptidagonisten mit insulinInfo
- Publication number
- ATE410182T1 ATE410182T1 AT98902423T AT98902423T ATE410182T1 AT E410182 T1 ATE410182 T1 AT E410182T1 AT 98902423 T AT98902423 T AT 98902423T AT 98902423 T AT98902423 T AT 98902423T AT E410182 T1 ATE410182 T1 AT E410182T1
- Authority
- AT
- Austria
- Prior art keywords
- approximately
- formulations
- insulin
- amylin
- peptid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/000288 WO1999034822A1 (en) | 1998-01-09 | 1998-01-09 | Formulations for amylin agonist peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE410182T1 true ATE410182T1 (de) | 2008-10-15 |
Family
ID=22266167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98902423T ATE410182T1 (de) | 1998-01-09 | 1998-01-09 | Formulierungen für amylin peptidagonisten mit insulin |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1044015B1 (de) |
JP (1) | JP4353544B2 (de) |
AT (1) | ATE410182T1 (de) |
AU (1) | AU760609B2 (de) |
CA (1) | CA2365742C (de) |
DE (1) | DE69840106D1 (de) |
DK (1) | DK1044015T3 (de) |
ES (1) | ES2316161T3 (de) |
WO (1) | WO1999034822A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001501593A (ja) | 1996-08-08 | 2001-02-06 | アミリン・ファーマシューティカルズ,インコーポレイテッド | 胃腸運動を調節するための方法 |
US5783556A (en) * | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
US7312196B2 (en) * | 1997-01-08 | 2007-12-25 | Amylin Pharmaceuticals, Inc. | Formulations for amylin agonist peptides |
JP4647736B2 (ja) * | 1999-09-30 | 2011-03-09 | 小林製薬株式会社 | 薬剤発散具 |
EP2036539A1 (de) | 2007-09-11 | 2009-03-18 | Novo Nordisk A/S | Stabile Formulierungen aus Amylin und dessen Analogen |
CN101822822A (zh) * | 2009-03-04 | 2010-09-08 | 北京德众万全药物技术开发有限公司 | 一种普兰林肽的药物组合物及其制备方法 |
JP2009149684A (ja) * | 2009-03-11 | 2009-07-09 | Amylin Pharmaceut Inc | アミリン作動薬ペプチド用製剤 |
CN102145164B (zh) * | 2010-12-16 | 2013-02-27 | 深圳市健元医药科技有限公司 | 一种更加稳定的iapp类似物注射剂 |
US9399065B2 (en) | 2012-04-16 | 2016-07-26 | Biodel Inc. | Magnesium compositions for modulating the pharmacokinetics and injection site pain of insulin |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
WO2014096150A1 (en) | 2012-12-21 | 2014-06-26 | Sanofi | Dual glp1/gip or trigonal glp1/gip/glucagon agonists |
WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
EP3080154B1 (de) | 2013-12-13 | 2018-02-07 | Sanofi | Duale glp-1/gip-rezeptoragonisten |
TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物 |
WO2015086730A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Non-acylated exendin-4 peptide analogues |
TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
EP3137494B1 (de) * | 2014-05-02 | 2021-08-04 | The Research Foundation for The State University of New York | Inselamyloidpolypeptide mit verbesserter löslichkeit |
US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
CN107952064B (zh) * | 2016-10-14 | 2023-10-20 | 江苏豪森药业集团有限公司 | 含有聚乙二醇洛塞那肽的药物制剂及其制备方法 |
US10463717B2 (en) * | 2016-12-27 | 2019-11-05 | Adocia | Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog, and a co-polyamino acid |
WO2018144671A1 (en) | 2017-02-01 | 2018-08-09 | The Research Foundation For The State University Of New York | Mutant islet amyloid polypeptides with improved solubility and methods for using the same |
PE20211202A1 (es) | 2017-08-24 | 2021-07-05 | Novo Nordisk As | Composiciones de glp-1 y sus usos |
US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
PE20221575A1 (es) | 2020-02-18 | 2022-10-06 | Novo Nordisk As | Formulaciones farmaceuticas |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4654324A (en) * | 1981-08-27 | 1987-03-31 | Eli Lilly And Company | Human proinsulin pharmaceutical formulations |
US5321008A (en) * | 1991-01-10 | 1994-06-14 | Amylin Pharmaceuticals, Inc. | Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions |
WO1993010146A1 (en) * | 1991-11-19 | 1993-05-27 | Amylin Pharmaceuticals, Inc. | Amylin agonist peptides and uses therefor |
US6143718A (en) * | 1995-06-07 | 2000-11-07 | Amylin Pharmaceuticals, Inc. | Treatment of Type II diabetes mellutis with amylin agonists |
US7910548B2 (en) * | 1997-06-06 | 2011-03-22 | Amylin Pharmaceuticals, Inc. | Methods for treating obesity |
-
1998
- 1998-01-09 JP JP53493999A patent/JP4353544B2/ja not_active Expired - Fee Related
- 1998-01-09 EP EP98902423A patent/EP1044015B1/de not_active Expired - Lifetime
- 1998-01-09 WO PCT/US1998/000288 patent/WO1999034822A1/en active IP Right Grant
- 1998-01-09 ES ES98902423T patent/ES2316161T3/es not_active Expired - Lifetime
- 1998-01-09 AU AU59094/98A patent/AU760609B2/en not_active Ceased
- 1998-01-09 DK DK98902423T patent/DK1044015T3/da active
- 1998-01-09 CA CA2365742A patent/CA2365742C/en not_active Expired - Fee Related
- 1998-01-09 DE DE69840106T patent/DE69840106D1/de not_active Expired - Lifetime
- 1998-01-09 AT AT98902423T patent/ATE410182T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69840106D1 (de) | 2008-11-20 |
JP4353544B2 (ja) | 2009-10-28 |
ES2316161T3 (es) | 2009-04-01 |
AU760609B2 (en) | 2003-05-15 |
WO1999034822A1 (en) | 1999-07-15 |
AU5909498A (en) | 1999-07-26 |
EP1044015B1 (de) | 2008-10-08 |
DK1044015T3 (da) | 2008-12-08 |
EP1044015A4 (de) | 2001-05-23 |
CA2365742A1 (en) | 1999-07-15 |
JP2002511103A (ja) | 2002-04-09 |
EP1044015A1 (de) | 2000-10-18 |
CA2365742C (en) | 2013-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |