JPS6397633A - 新規なキトサン粒状物 - Google Patents
新規なキトサン粒状物Info
- Publication number
- JPS6397633A JPS6397633A JP24254586A JP24254586A JPS6397633A JP S6397633 A JPS6397633 A JP S6397633A JP 24254586 A JP24254586 A JP 24254586A JP 24254586 A JP24254586 A JP 24254586A JP S6397633 A JPS6397633 A JP S6397633A
- Authority
- JP
- Japan
- Prior art keywords
- chitosan
- granules
- aqueous solution
- particle size
- dimethylformamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001661 Chitosan Polymers 0.000 title claims description 60
- 239000008187 granular material Substances 0.000 title claims description 38
- 239000007864 aqueous solution Substances 0.000 claims description 17
- 239000002245 particle Substances 0.000 claims description 17
- 230000002378 acidificating effect Effects 0.000 claims description 13
- -1 diisocyanate compound Chemical class 0.000 claims description 9
- 150000001491 aromatic compounds Chemical class 0.000 claims description 7
- 239000003637 basic solution Substances 0.000 claims description 7
- 238000004132 cross linking Methods 0.000 claims description 6
- 238000000465 moulding Methods 0.000 claims description 5
- 239000013543 active substance Substances 0.000 claims description 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 51
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- 239000000725 suspension Substances 0.000 description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- 238000004113 cell culture Methods 0.000 description 8
- 238000003756 stirring Methods 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 6
- 230000002522 swelling effect Effects 0.000 description 6
- 239000005057 Hexamethylene diisocyanate Substances 0.000 description 4
- RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000007935 neutral effect Effects 0.000 description 4
- 239000002798 polar solvent Substances 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- MGNCLNQXLYJVJD-UHFFFAOYSA-N cyanuric chloride Chemical compound ClC1=NC(Cl)=NC(Cl)=N1 MGNCLNQXLYJVJD-UHFFFAOYSA-N 0.000 description 3
- 230000006196 deacetylation Effects 0.000 description 3
- 238000003381 deacetylation reaction Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- LGRFSURHDFAFJT-UHFFFAOYSA-N Phthalic anhydride Natural products C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 239000006096 absorbing agent Substances 0.000 description 2
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 description 2
- ISAOCJYIOMOJEB-UHFFFAOYSA-N benzoin Chemical compound C=1C=CC=CC=1C(O)C(=O)C1=CC=CC=C1 ISAOCJYIOMOJEB-UHFFFAOYSA-N 0.000 description 2
- JXTHNDFMNIQAHM-UHFFFAOYSA-N dichloroacetic acid Chemical compound OC(=O)C(Cl)Cl JXTHNDFMNIQAHM-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- MSWZFWKMSRAUBD-IVMDWMLBSA-N glucosamine group Chemical group OC1[C@H](N)[C@@H](O)[C@H](O)[C@H](O1)CO MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- FKTHNVSLHLHISI-UHFFFAOYSA-N 1,2-bis(isocyanatomethyl)benzene Chemical compound O=C=NCC1=CC=CC=C1CN=C=O FKTHNVSLHLHISI-UHFFFAOYSA-N 0.000 description 1
- ZXHZWRZAWJVPIC-UHFFFAOYSA-N 1,2-diisocyanatonaphthalene Chemical compound C1=CC=CC2=C(N=C=O)C(N=C=O)=CC=C21 ZXHZWRZAWJVPIC-UHFFFAOYSA-N 0.000 description 1
- ALQLPWJFHRMHIU-UHFFFAOYSA-N 1,4-diisocyanatobenzene Chemical compound O=C=NC1=CC=C(N=C=O)C=C1 ALQLPWJFHRMHIU-UHFFFAOYSA-N 0.000 description 1
- CDMDQYCEEKCBGR-UHFFFAOYSA-N 1,4-diisocyanatocyclohexane Chemical compound O=C=NC1CCC(N=C=O)CC1 CDMDQYCEEKCBGR-UHFFFAOYSA-N 0.000 description 1
- NOGFHTGYPKWWRX-UHFFFAOYSA-N 2,2,6,6-tetramethyloxan-4-one Chemical compound CC1(C)CC(=O)CC(C)(C)O1 NOGFHTGYPKWWRX-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- 239000006145 Eagle's minimal essential medium Substances 0.000 description 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
- 244000028419 Styrax benzoin Species 0.000 description 1
- 235000000126 Styrax benzoin Nutrition 0.000 description 1
- 235000008411 Sumatra benzointree Nutrition 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 229940095076 benzaldehyde Drugs 0.000 description 1
- 229960002130 benzoin Drugs 0.000 description 1
- KCXMKQUNVWSEMD-UHFFFAOYSA-N benzyl chloride Chemical compound ClCC1=CC=CC=C1 KCXMKQUNVWSEMD-UHFFFAOYSA-N 0.000 description 1
- 229940073608 benzyl chloride Drugs 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- JHIWVOJDXOSYLW-UHFFFAOYSA-N butyl 2,2-difluorocyclopropane-1-carboxylate Chemical compound CCCCOC(=O)C1CC1(F)F JHIWVOJDXOSYLW-UHFFFAOYSA-N 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 229960005215 dichloroacetic acid Drugs 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 235000019382 gum benzoic Nutrition 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
Landscapes
- Processes Of Treating Macromolecular Substances (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24254586A JPS6397633A (ja) | 1986-10-13 | 1986-10-13 | 新規なキトサン粒状物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24254586A JPS6397633A (ja) | 1986-10-13 | 1986-10-13 | 新規なキトサン粒状物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6397633A true JPS6397633A (ja) | 1988-04-28 |
| JPH0455609B2 JPH0455609B2 (enrdf_load_stackoverflow) | 1992-09-03 |
Family
ID=17090701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP24254586A Granted JPS6397633A (ja) | 1986-10-13 | 1986-10-13 | 新規なキトサン粒状物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6397633A (enrdf_load_stackoverflow) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02227077A (ja) * | 1988-11-07 | 1990-09-10 | Nippon Shinyaku Co Ltd | 固定化酸素及び利用法 |
| EP0743067A3 (en) * | 1995-05-16 | 1998-07-08 | Toray Industries, Inc. | Use of urea and thiourea compounds for elimination or detoxofication of superantigens from body fluids |
| US6693188B2 (en) | 2001-08-08 | 2004-02-17 | Cargill Incorporated | N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine |
| US6972284B2 (en) | 2000-03-15 | 2005-12-06 | Cargill, Incorporated | Chitosan and method of preparing chitosan |
| US7488812B2 (en) | 2002-04-02 | 2009-02-10 | Cargill, Incorporated | Chitosan production |
| US7816514B2 (en) | 2001-02-16 | 2010-10-19 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
| JP2011500955A (ja) * | 2007-10-30 | 2011-01-06 | ヴィスコゲル アーベー | キトサン組成物 |
| US7923437B2 (en) | 2001-02-16 | 2011-04-12 | Cargill, Incorporated | Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same |
| US8222232B2 (en) | 2001-02-16 | 2012-07-17 | Cargill, Incorporated | Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass |
| US8231021B2 (en) | 2007-06-01 | 2012-07-31 | Magata Fuji Chemical Co., Ltd. | Strip-shaped handle part for drinking water bottle |
-
1986
- 1986-10-13 JP JP24254586A patent/JPS6397633A/ja active Granted
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02227077A (ja) * | 1988-11-07 | 1990-09-10 | Nippon Shinyaku Co Ltd | 固定化酸素及び利用法 |
| EP0743067A3 (en) * | 1995-05-16 | 1998-07-08 | Toray Industries, Inc. | Use of urea and thiourea compounds for elimination or detoxofication of superantigens from body fluids |
| US5928633A (en) * | 1995-05-16 | 1999-07-27 | Toray Industries, Inc. | Material for elimination or detoxification of super antigens |
| US6190688B1 (en) | 1995-05-16 | 2001-02-20 | Toray Industries, Inc. | Material for elimination or detoxification of super antigens |
| US7413881B2 (en) | 2000-03-15 | 2008-08-19 | Cargill, Incorporated | Chitosan and method of preparing chitosan |
| US6972284B2 (en) | 2000-03-15 | 2005-12-06 | Cargill, Incorporated | Chitosan and method of preparing chitosan |
| US7816514B2 (en) | 2001-02-16 | 2010-10-19 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
| US7923437B2 (en) | 2001-02-16 | 2011-04-12 | Cargill, Incorporated | Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same |
| US8034925B2 (en) | 2001-02-16 | 2011-10-11 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
| US8222232B2 (en) | 2001-02-16 | 2012-07-17 | Cargill, Incorporated | Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass |
| US6693188B2 (en) | 2001-08-08 | 2004-02-17 | Cargill Incorporated | N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine |
| US7488812B2 (en) | 2002-04-02 | 2009-02-10 | Cargill, Incorporated | Chitosan production |
| US8231021B2 (en) | 2007-06-01 | 2012-07-31 | Magata Fuji Chemical Co., Ltd. | Strip-shaped handle part for drinking water bottle |
| JP2011500955A (ja) * | 2007-10-30 | 2011-01-06 | ヴィスコゲル アーベー | キトサン組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0455609B2 (enrdf_load_stackoverflow) | 1992-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4981960A (en) | Modified cellulose for biocompatible dialysis membranes IV and process for preparation thereof | |
| EP0021750B1 (en) | Production of spherically shaped material made of chitin derivative | |
| JPS6397633A (ja) | 新規なキトサン粒状物 | |
| JPH0678425B2 (ja) | 重合体の新規製造法 | |
| EP2137219A1 (en) | Method for making a polysaccharide dialdehyde having high purity | |
| US4680381A (en) | Process for isolating polymer | |
| CN117843832A (zh) | 改性透明质酸及其在医美填充剂上的应用 | |
| JPS6354285B2 (enrdf_load_stackoverflow) | ||
| JPH06233691A (ja) | バクテリアセルロースのキセロゲルの製法及びそれにより 製造された誘導体 | |
| KR100440601B1 (ko) | 폴리아세트산비닐의 비누화 방법 및 그에 의해 제조되는미세구형 입자상 폴리비닐알코올 | |
| JPS5829801A (ja) | Ｎ−アシル化キトサンの製造方法 | |
| JPH09165404A (ja) | 表面ｎ−チオカルバモイル化キトサン成形体およびその製造方法 | |
| JPH03221505A (ja) | シクロデキストリンポリマーの合成方法及びシクロデキストリン膜の製造方法 | |
| JPS63182304A (ja) | 微結晶キトサンおよびその製造方法 | |
| US4337095A (en) | Process for the preparation of solutions of cellulose derivatives in organic solvents having higher concentration and solutions obtained by said process | |
| JPS58118801A (ja) | 超吸湿性セルロ−ス誘導体 | |
| JP2907492B2 (ja) | ヘパリン徐放性材料およびその製造法 | |
| JP3994210B2 (ja) | イオン交換樹脂の精製法 | |
| CN118599036A (zh) | 一种绿色微溶胀制备改性聚乙烯醇的方法 | |
| JP2612183B2 (ja) | セルロース誘導体およびその製造方法 | |
| CN110723910B (zh) | 一种控制细胞黏附和脱离的细胞培养材料及制备方法 | |
| CN101812212B (zh) | 一种改性聚丙烯树脂及其制备方法 | |
| JP2649701B2 (ja) | 血管壁細胞の培養方法 | |
| JP2005289883A (ja) | 生体吸収性止血剤およびその製造方法 | |
| RU2069215C1 (ru) | Способ получения ацетонорастворимого ацетата целлюлозы |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |