JPS6327350B2 - - Google Patents

Info

Publication number
JPS6327350B2
JPS6327350B2 JP54014534A JP1453479A JPS6327350B2 JP S6327350 B2 JPS6327350 B2 JP S6327350B2 JP 54014534 A JP54014534 A JP 54014534A JP 1453479 A JP1453479 A JP 1453479A JP S6327350 B2 JPS6327350 B2 JP S6327350B2
Authority
JP
Japan
Prior art keywords
azabicyclo
cis
oct
group
reference example
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54014534A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55108877A (en
Inventor
Tadashi Hirata
Yukio Hashimoto
Takehiro Ogasa
Shigeru Kobayashi
Masao Matsukuma
Kazuo Kimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP1453479A priority Critical patent/JPS55108877A/ja
Priority to NO800315A priority patent/NO155548C/no
Priority to CA000345348A priority patent/CA1171373A/en
Priority to AU55382/80A priority patent/AU5538280A/en
Priority to DK054880A priority patent/DK170255B1/da
Priority to ES488428A priority patent/ES488428A0/es
Priority to DE8080100666T priority patent/DE3064509D1/de
Priority to EP80100666A priority patent/EP0014476B1/en
Publication of JPS55108877A publication Critical patent/JPS55108877A/ja
Priority to ES495037A priority patent/ES495037A0/es
Priority to NO841499A priority patent/NO841499L/no
Priority to US06/921,193 priority patent/US4755596A/en
Publication of JPS6327350B2 publication Critical patent/JPS6327350B2/ja
Priority to MX9203636A priority patent/MX9203636A/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP1453479A 1979-02-10 1979-02-10 Optically active cephalosporin analog Granted JPS55108877A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP1453479A JPS55108877A (en) 1979-02-10 1979-02-10 Optically active cephalosporin analog
NO800315A NO155548C (no) 1979-02-10 1980-02-06 Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
CA000345348A CA1171373A (en) 1979-02-10 1980-02-07 Optically active cephalosporin analogs
EP80100666A EP0014476B1 (en) 1979-02-10 1980-02-08 Optically active acylated cephalosporin analogs, processes for their preparation and pharmaceutical compositions comprising them
DK054880A DK170255B1 (da) 1979-02-10 1980-02-08 Analogifremgangsmåde til fremstilling af optisk aktive cephalosporin-analoge
ES488428A ES488428A0 (es) 1979-02-10 1980-02-08 Un procedimiento para la preparacion de analogos de cefalos-porina
DE8080100666T DE3064509D1 (en) 1979-02-10 1980-02-08 Optically active acylated cephalosporin analogs, processes for their preparation and pharmaceutical compositions comprising them
AU55382/80A AU5538280A (en) 1979-02-10 1980-02-08 1-azabicyclo (4,2,0) oct-2-em derivatives
ES495037A ES495037A0 (es) 1979-02-10 1980-09-12 Un procedimiento para la produccion de compuestos opticamen-te activos de analogos de cefalosporina
NO841499A NO841499L (no) 1979-02-10 1984-04-13 Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoge
US06/921,193 US4755596A (en) 1979-02-10 1986-10-21 Optically active carbacephems
MX9203636A MX9203636A (es) 1979-02-10 1992-06-26 Compuestos analogos de cefalosporina y composiciones farmaceuticas que los contienen.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1453479A JPS55108877A (en) 1979-02-10 1979-02-10 Optically active cephalosporin analog

Publications (2)

Publication Number Publication Date
JPS55108877A JPS55108877A (en) 1980-08-21
JPS6327350B2 true JPS6327350B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-06-02

Family

ID=11863804

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1453479A Granted JPS55108877A (en) 1979-02-10 1979-02-10 Optically active cephalosporin analog

Country Status (2)

Country Link
US (1) US4755596A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS55108877A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
US4755596A (en) 1988-07-05
JPS55108877A (en) 1980-08-21

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