JPS6323989B2 - - Google Patents

Info

Publication number
JPS6323989B2
JPS6323989B2 JP54042611A JP4261179A JPS6323989B2 JP S6323989 B2 JPS6323989 B2 JP S6323989B2 JP 54042611 A JP54042611 A JP 54042611A JP 4261179 A JP4261179 A JP 4261179A JP S6323989 B2 JPS6323989 B2 JP S6323989B2
Authority
JP
Japan
Prior art keywords
formula
compounds
compound
cyclohexenyl
trimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54042611A
Other languages
English (en)
Japanese (ja)
Other versions
JPS54135752A (en
Inventor
Henni Rarufu
Raizaa Gotoriibu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS54135752A publication Critical patent/JPS54135752A/ja
Publication of JPS6323989B2 publication Critical patent/JPS6323989B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP4261179A 1978-04-12 1979-04-10 Nonatetraene acid derivative Granted JPS54135752A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/895,942 US4169103A (en) 1978-04-12 1978-04-12 Nonatetraenoic acid derivatives

Publications (2)

Publication Number Publication Date
JPS54135752A JPS54135752A (en) 1979-10-22
JPS6323989B2 true JPS6323989B2 (cg-RX-API-DMAC10.html) 1988-05-18

Family

ID=25405331

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4261179A Granted JPS54135752A (en) 1978-04-12 1979-04-10 Nonatetraene acid derivative

Country Status (4)

Country Link
US (1) US4169103A (cg-RX-API-DMAC10.html)
EP (1) EP0004680B1 (cg-RX-API-DMAC10.html)
JP (1) JPS54135752A (cg-RX-API-DMAC10.html)
DE (1) DE2960972D1 (cg-RX-API-DMAC10.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651007A5 (de) * 1982-06-24 1985-08-30 Hoffmann La Roche Polyenverbindungen.
US4539154A (en) * 1983-06-15 1985-09-03 Hoffmann-La Roche Inc. Polyene compounds
CH658387A5 (de) * 1984-04-02 1986-11-14 Hoffmann La Roche Pharmazeutische praeparate.
US4648996A (en) * 1984-07-27 1987-03-10 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4883613A (en) * 1984-07-27 1989-11-28 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4883614A (en) * 1984-07-27 1989-11-28 Hoffman-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4894480A (en) * 1984-07-27 1990-01-16 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4780251A (en) * 1984-07-27 1988-10-25 Hoffman-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4843096A (en) * 1985-06-26 1989-06-27 Stiefel Laboratories, Inc. Treatment of acne
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider
US5124083A (en) * 1990-08-30 1992-06-23 Southern Research Institute 3-substituted and 3,3-disubstituted 4-oxoretinoic acids and their esters
TW442459B (en) * 1996-04-15 2001-06-23 Hoffmann La Roche Retinoid compounds, pharmaceutical composition comprising same and process for the preparation thereof
JP2004509073A (ja) * 2000-07-11 2004-03-25 ユニバーシティ・オブ・メリーランド，　ボルティモア 新規なｃ−４置換レチノイド
KR101194137B1 (ko) * 2004-10-13 2012-10-25 가부시키가이샤 메이지 ＳＴＡＴ３ 인산화 억제 및 Ｎｏｔｃｈ１ 발현 억제제
EP1971331A2 (en) * 2005-12-09 2008-09-24 Basilea Pharmaceutica AG 4-oxo-(iso)tretinoin for the topical treatment of severe dermatological disorders

Also Published As

Publication number Publication date
JPS54135752A (en) 1979-10-22
EP0004680B1 (de) 1981-10-14
EP0004680A3 (en) 1979-11-28
EP0004680A2 (de) 1979-10-17
DE2960972D1 (en) 1981-12-24
US4169103A (en) 1979-09-25

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