JPS6315247B2 - - Google Patents
Info
- Publication number
- JPS6315247B2 JPS6315247B2 JP7421475A JP7421475A JPS6315247B2 JP S6315247 B2 JPS6315247 B2 JP S6315247B2 JP 7421475 A JP7421475 A JP 7421475A JP 7421475 A JP7421475 A JP 7421475A JP S6315247 B2 JPS6315247 B2 JP S6315247B2
- Authority
- JP
- Japan
- Prior art keywords
- streptococcus
- milk
- miutans
- aht
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000194017 Streptococcus Species 0.000 claims description 40
- 235000013336 milk Nutrition 0.000 claims description 26
- 239000008267 milk Substances 0.000 claims description 26
- 210000004080 milk Anatomy 0.000 claims description 26
- 241000194019 Streptococcus mutans Species 0.000 claims description 10
- 108060003951 Immunoglobulin Proteins 0.000 claims description 9
- 102000018358 immunoglobulin Human genes 0.000 claims description 9
- 230000003053 immunization Effects 0.000 claims description 8
- 238000002649 immunization Methods 0.000 claims description 6
- 235000013365 dairy product Nutrition 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 238000010255 intramuscular injection Methods 0.000 claims description 3
- 239000007927 intramuscular injection Substances 0.000 claims description 3
- 229940072221 immunoglobulins Drugs 0.000 claims description 2
- 102000006395 Globulins Human genes 0.000 claims 1
- 108010044091 Globulins Proteins 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 description 20
- 241000700159 Rattus Species 0.000 description 16
- 235000005911 diet Nutrition 0.000 description 13
- 230000037213 diet Effects 0.000 description 13
- 208000002925 dental caries Diseases 0.000 description 12
- 230000001580 bacterial effect Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 7
- 239000000427 antigen Substances 0.000 description 7
- 102000036639 antigens Human genes 0.000 description 7
- 108091007433 antigens Proteins 0.000 description 7
- 235000013305 food Nutrition 0.000 description 7
- 235000008476 powdered milk Nutrition 0.000 description 7
- 230000006510 metastatic growth Effects 0.000 description 6
- 210000002966 serum Anatomy 0.000 description 6
- 239000000047 product Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000003298 dental enamel Anatomy 0.000 description 4
- 210000000214 mouth Anatomy 0.000 description 4
- 230000000405 serological effect Effects 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000004520 agglutination Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002324 mouth wash Substances 0.000 description 2
- 229940051866 mouthwash Drugs 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 235000020183 skimmed milk Nutrition 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 235000009355 Dianthus caryophyllus Nutrition 0.000 description 1
- 240000006497 Dianthus caryophyllus Species 0.000 description 1
- 238000010159 Duncan test Methods 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 102000004407 Lactalbumin Human genes 0.000 description 1
- 108090000942 Lactalbumin Proteins 0.000 description 1
- 229920000715 Mucilage Polymers 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 241000194023 Streptococcus sanguinis Species 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000004523 agglutinating effect Effects 0.000 description 1
- 238000000540 analysis of variance Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 229960001212 bacterial vaccine Drugs 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000001013 cariogenic effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000020247 cow milk Nutrition 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000004373 mandible Anatomy 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 235000021243 milk fat Nutrition 0.000 description 1
- LJYRLGOJYKPILZ-UHFFFAOYSA-N murexide Chemical compound [NH4+].N1C(=O)NC(=O)C(N=C2C(NC(=O)NC2=O)=O)=C1[O-] LJYRLGOJYKPILZ-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
Landscapes
- Dairy Products (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7421475A JPS521014A (en) | 1975-06-17 | 1975-06-17 | Pharmaceutically acceptable carrier containing milk immunoglobulin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7421475A JPS521014A (en) | 1975-06-17 | 1975-06-17 | Pharmaceutically acceptable carrier containing milk immunoglobulin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS521014A JPS521014A (en) | 1977-01-06 |
| JPS6315247B2 true JPS6315247B2 (https=) | 1988-04-04 |
Family
ID=13540705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7421475A Granted JPS521014A (en) | 1975-06-17 | 1975-06-17 | Pharmaceutically acceptable carrier containing milk immunoglobulin |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS521014A (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE448344B (sv) * | 1978-02-06 | 1987-02-16 | Stolle Res & Dev | Antikropp for behandling av reumatoid artrit samt sett att framstella denna |
| JPS58154513A (ja) * | 1982-03-09 | 1983-09-14 | Sendai Biseibutsu Kenkyusho | 予防及び治療薬 |
| JPS59184153U (ja) * | 1983-05-24 | 1984-12-07 | 富士ゼロックス株式会社 | 荷重可変型用紙剥離爪 |
| JPS6028937A (ja) * | 1983-07-25 | 1985-02-14 | Kitasato Inst:The | 非う蝕性抗体および組成物 |
-
1975
- 1975-06-17 JP JP7421475A patent/JPS521014A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS521014A (en) | 1977-01-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4324782A (en) | Dental caries inhibiting product of immunized cow's milk having antibodies specific to killed Streptococcus mutans cells | |
| CN1229139C (zh) | 抗耳炎的预防免疫牛奶制剂 | |
| US9750802B2 (en) | Method and system for targeting the microbiome to promote health and treat allergic and inflammatory diseases | |
| JP2698778B2 (ja) | トリの抗体を用いた哺乳動物の受動免疫化 | |
| US5585098A (en) | Oral administration of chicken yolk immunoglobulins to lower somatic cell count in the milk of lactating ruminants | |
| Krobicka et al. | The effects of cheese snacks on caries in desalivated rats | |
| JP2002501526A (ja) | 乳汁における免疫グロブリンａの生成方法 | |
| KR910005409B1 (ko) | 계란으로 부터의 특이적항체함유재료의 제조방법 | |
| JPH0160455B2 (https=) | ||
| JPH02160726A (ja) | ワクチン | |
| JPS6315247B2 (https=) | ||
| WO2009093605A1 (ja) | 抗イヌ歯周病組成物 | |
| JPS60146834A (ja) | 歯周炎抑制用抗体の製法及び同抗体を含有する歯周炎抑制用組成物 | |
| JP2912451B2 (ja) | ハチミツのワクチンとしての用途 | |
| JPH0920684A (ja) | チューインガム | |
| JPH05227916A (ja) | う蝕予防食品 | |
| JP2689511B2 (ja) | 食 品 | |
| JP4982629B2 (ja) | 抗体、及び抗体を含む抗歯周病組成物 | |
| KR100627635B1 (ko) | 가축에서 유선 분비 항체를 제조하는 방법 | |
| JPH06345668A (ja) | 感染防御組成物およびその用途 | |
| DE2522999A1 (de) | Mittel mit antikarieswirkung, dessen herstellung und verwendung | |
| JP3597784B2 (ja) | 消化性潰瘍抑制組成物及びそれを含有する飲食品 | |
| JPH03279398A (ja) | 抗体及びそれを有効成分とするう蝕予防組成物 | |
| WO2007068058A1 (en) | Hyper immune bovine colostrum gastrointestinal vaccine | |
| CH625415A5 (en) | Process for the production of milk with an anticaries action and use thereof for the production of a composition with an anticaries action |