JPS6272657A - アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤 - Google Patents

アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤

Info

Publication number
JPS6272657A
JPS6272657A JP60214195A JP21419585A JPS6272657A JP S6272657 A JPS6272657 A JP S6272657A JP 60214195 A JP60214195 A JP 60214195A JP 21419585 A JP21419585 A JP 21419585A JP S6272657 A JPS6272657 A JP S6272657A
Authority
JP
Japan
Prior art keywords
group
dimethoxy
formula
lipoxygenase
hydroxy group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP60214195A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0437071B2 (enExample
Inventor
Makoto Takai
誠 高井
Noriie Itou
伊藤　徳家
Makoto Hattori
信 服部
Hirokazu Hasegawa
弘和 長谷川
Toshio Wakabayashi
若林　利生
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Priority to JP60214195A priority Critical patent/JPS6272657A/ja
Priority to DE8686113087T priority patent/DE3688032T2/de
Priority to EP86113087A priority patent/EP0217271B1/en
Priority to US06/912,261 priority patent/US4816486A/en
Publication of JPS6272657A publication Critical patent/JPS6272657A/ja
Publication of JPH0437071B2 publication Critical patent/JPH0437071B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP60214195A 1985-09-27 1985-09-27 アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤 Granted JPS6272657A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP60214195A JPS6272657A (ja) 1985-09-27 1985-09-27 アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤
DE8686113087T DE3688032T2 (de) 1985-09-27 1986-09-23 Amidderivate und diese enthaltende 5-lipoxygenase-inhibitoren.
EP86113087A EP0217271B1 (en) 1985-09-27 1986-09-23 Amide derivatives and 5-lypoxygenase inhibitors containing the same
US06/912,261 US4816486A (en) 1985-09-27 1986-09-29 Amide derivatives and 5-lypoxygenase inhibitors containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60214195A JPS6272657A (ja) 1985-09-27 1985-09-27 アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤

Publications (2)

Publication Number Publication Date
JPS6272657A true JPS6272657A (ja) 1987-04-03
JPH0437071B2 JPH0437071B2 (enExample) 1992-06-18

Family

ID=16651808

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60214195A Granted JPS6272657A (ja) 1985-09-27 1985-09-27 アミド誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤

Country Status (4)

Country Link
US (1) US4816486A (enExample)
EP (1) EP0217271B1 (enExample)
JP (1) JPS6272657A (enExample)
DE (1) DE3688032T2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4401708A1 (de) * 1994-01-21 1995-07-27 Henkel Kgaa Polymerkonzentrat und Verwendung
CN107233337A (zh) 2009-04-29 2017-10-10 阿马里纳药物爱尔兰有限公司 含有epa和心血管剂的药物组合物以及使用其的方法
EP2580188A1 (en) 2010-06-14 2013-04-17 Cilpa Limited A process for the preparation of nateglinide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192213A (en) * 1962-10-12 1965-06-29 Olin Mathieson Aminoalkyl anilides
US3268407A (en) * 1963-10-04 1966-08-23 American Cyanamid Co Tranquilizing compositions and method of inducing a state of tranquility
IT1094864B (it) * 1978-05-29 1985-08-10 Tosi Franco Ist Derivati della bromexina e procedimento per la loro preparazione
US4337270A (en) * 1980-05-21 1982-06-29 Hisamitsu Pharmaceutical Co., Inc. Novel anthranilic acid derivatives
DK110582A (da) * 1981-03-19 1982-09-20 Hokuriku Pharmaceutical 2-benzoylamino-substituerede benzylaminderivater samt fremgangsmaade til fremstilling af samme
US4562201A (en) * 1982-07-26 1985-12-31 American Hospital Supply Corporation Aminomethyl benzanilides
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US4536346A (en) * 1983-05-06 1985-08-20 American Cyanamid Company Aralkanamidophenyl compounds
US4673684A (en) * 1984-04-04 1987-06-16 Terumo Corporation Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient

Also Published As

Publication number Publication date
JPH0437071B2 (enExample) 1992-06-18
US4816486A (en) 1989-03-28
DE3688032D1 (de) 1993-04-22
EP0217271B1 (en) 1993-03-17
DE3688032T2 (de) 1993-09-16
EP0217271A2 (en) 1987-04-08
EP0217271A3 (en) 1989-01-11

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