JPS61500665A - キサンチン類を含んでなる鎮痛および抗炎症組成物およびその使用法 - Google Patents

キサンチン類を含んでなる鎮痛および抗炎症組成物およびその使用法

Info

Publication number
JPS61500665A
JPS61500665A JP60500078A JP50007884A JPS61500665A JP S61500665 A JPS61500665 A JP S61500665A JP 60500078 A JP60500078 A JP 60500078A JP 50007884 A JP50007884 A JP 50007884A JP S61500665 A JPS61500665 A JP S61500665A
Authority
JP
Japan
Prior art keywords
derivative
alkyl
xanthine
composition according
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60500078A
Other languages
English (en)
Japanese (ja)
Inventor
サンシヤイン，アブラハム
ラスカ，ユージーン　エム
シーゲル，キヤロル　イー
Original Assignee
リチヤ−ドソン−ビツクス，インコ−ポレイテイド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by リチヤ−ドソン−ビツクス，インコ−ポレイテイド filed Critical リチヤ−ドソン−ビツクス，インコ−ポレイテイド
Publication of JPS61500665A publication Critical patent/JPS61500665A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP60500078A 1983-12-12 1984-12-12 キサンチン類を含んでなる鎮痛および抗炎症組成物およびその使用法 Pending JPS61500665A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/560,576 US4558051A (en) 1983-10-11 1983-12-12 Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US560576 1983-12-12

Publications (1)

Publication Number Publication Date
JPS61500665A true JPS61500665A (ja) 1986-04-10

Family

ID=24238396

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60500078A Pending JPS61500665A (ja) 1983-12-12 1984-12-12 キサンチン類を含んでなる鎮痛および抗炎症組成物およびその使用法

Country Status (15)

Country Link
US (1) US4558051A (https=)
EP (1) EP0165308B1 (https=)
JP (1) JPS61500665A (https=)
AT (1) AT389997B (https=)
AU (1) AU574419B2 (https=)
CA (1) CA1246453A (https=)
CH (1) CH669730A5 (https=)
DE (1) DE3490583T1 (https=)
GB (1) GB2161076B (https=)
IE (1) IE58158B1 (https=)
IT (1) IT1177389B (https=)
NL (1) NL8420316A (https=)
SE (1) SE469874B (https=)
WO (1) WO1985002540A1 (https=)
ZA (1) ZA849675B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63122623A (ja) * 1986-10-31 1988-05-26 ユーロセルテイツク・エス・アー 徐放性ヒドロモルホン組成物

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3508097A1 (de) * 1984-07-21 1986-02-06 Hoechst Ag, 6230 Frankfurt Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung
HU197746B (en) * 1985-09-05 1989-05-29 Sandoz Ag Process for producing xantin derivatives and pharmaceutical compositions containing them
CH669523A5 (https=) * 1986-06-25 1989-03-31 Mepha Ag
DE3779374D1 (en) * 1986-08-28 1992-07-02 Sandoz Ag Xanthinderivate.
CH670090A5 (https=) * 1986-10-27 1989-05-12 Nestle Sa
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US5196430A (en) * 1986-12-31 1993-03-23 Hoechst-Roussel Pharmaceuticals Inc. Method of inhibiting the activity of leukocyte derived cytokines
US5272153A (en) * 1986-12-31 1993-12-21 Hoechst-Roussel Pharmaceuticals, Inc. Method of inhibiting the activity of leukocyte derived cytokines
US5196429A (en) * 1986-12-31 1993-03-23 Hoechst-Roussel Pharmaceuticals Inc. Method of inhibiting the activity of leukocyte derived cytokines
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US4859704A (en) * 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
NZ226934A (en) * 1987-11-13 1991-01-29 Glaxo Group Ltd Phenethanolamine derivatives and pharmaceutical compositions
US4883818A (en) * 1987-11-17 1989-11-28 Analgesic Associates Onset-hastened/enhanced analgesia
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
KR930701994A (ko) * 1990-09-11 1993-09-08 제이코브스 코넬리스 레이서 개선된 진통 효과를 제공하는 방법
EP0663819A4 (en) * 1992-09-29 1998-05-27 Merck & Co Inc COMBINATION OF IBUPROFENE AND CAFFEINE.
US5340813A (en) * 1992-11-09 1994-08-23 Cell Therapeutics, Inc. Substituted aminoalkyl xanthine compounds
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
US5451409A (en) * 1993-11-22 1995-09-19 Rencher; William F. Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6586429B2 (en) * 2000-11-29 2003-07-01 Cell Therapeutics, Inc. Tricyclic fused xanthine compounds and their uses
CN1610551A (zh) 2001-07-06 2005-04-27 恩德制药公司 用作止痛剂的6－羟基羟吗啡酮的肠胃外给药
KR20030048026A (ko) 2001-07-06 2003-06-18 펜웨스트 파머슈티칼즈 컴파니 옥시모르폰의 서방형 제제
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
US7317017B2 (en) * 2002-11-08 2008-01-08 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
US7125993B2 (en) * 2001-11-09 2006-10-24 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
DK1444233T3 (da) 2001-11-09 2011-10-17 Gilead Palo Alto Inc A2B-adenosinreceptorantagonister
US6977300B2 (en) * 2001-11-09 2005-12-20 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
US20080318983A1 (en) * 2001-11-09 2008-12-25 Rao Kalla A2b adenosine receptor antagonists
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
MX2007002437A (es) * 2004-09-01 2007-08-14 Cv Therapeutics Inc Metodo para el sanado de heridas utilizando antagonistas del receptor de adenosina a2b.
CL2007002425A1 (es) * 2006-08-22 2008-06-27 Albermarle Corp Procedimiento de preparacion controlado de sal sodica de ibuprofeno de tamano de particula mediano; y dichas particulas de sal sodica.
US9593118B2 (en) 2015-04-08 2017-03-14 Lewis And Clark Pharmaceuticals, Inc. Xanthine-substituted alkynyl carbamates/reverse carbamates as A2B antagonists
CN109912598B (zh) * 2019-03-27 2022-09-13 四川大学华西医院 防治炎症反应的核苷类衍生物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3439094A (en) * 1967-07-20 1969-04-15 Warner Lambert Pharmaceutical Analgesic compositions containing namol xenyrate,caffeine and acetyl-rho-aminophenol
US3936528A (en) * 1974-02-13 1976-02-03 Syntex Corporation Analgesic formulations having enhanced therapeutic activity
AU532600B2 (en) * 1977-04-02 1983-10-06 Hoechst A.G. Alkenyl xanthines and pharmaceutical compositions
JPS56154416A (en) * 1980-04-30 1981-11-30 Kaken Pharmaceut Co Ltd Antipyretic analgesic composition
ZA835324B (en) * 1982-07-22 1984-09-26 Abraham Sunshine Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4420483A (en) * 1982-07-22 1983-12-13 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same
US4479956A (en) * 1983-04-26 1984-10-30 Analgeic Associates Analgesic compositions comprising propiram and methods of using same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63122623A (ja) * 1986-10-31 1988-05-26 ユーロセルテイツク・エス・アー 徐放性ヒドロモルホン組成物

Also Published As

Publication number Publication date
AU3747485A (en) 1985-06-26
ATA905384A (de) 1989-08-15
GB2161076B (en) 1988-03-30
GB8519256D0 (en) 1985-09-04
IT1177389B (it) 1987-08-26
AT389997B (de) 1990-02-26
DE3490583T1 (de) 1986-04-03
ZA849675B (en) 1985-07-31
EP0165308A1 (en) 1985-12-27
IE58158B1 (en) 1993-07-28
WO1985002540A1 (en) 1985-06-20
IT8424009A0 (it) 1984-12-12
SE8503762D0 (sv) 1985-08-09
AU574419B2 (en) 1988-07-07
IT8424009A1 (it) 1986-06-12
NL8420316A (nl) 1985-11-01
CH669730A5 (https=) 1989-04-14
EP0165308B1 (en) 1989-03-22
SE469874B (sv) 1993-10-04
EP0165308A4 (en) 1986-05-16
IE843166L (en) 1985-06-12
CA1246453A (en) 1988-12-13
GB2161076A (en) 1986-01-08
SE8503762L (sv) 1985-08-09
US4558051A (en) 1985-12-10

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