JPS6147511B2 - - Google Patents

Info

Publication number
JPS6147511B2
JPS6147511B2 JP53091044A JP9104478A JPS6147511B2 JP S6147511 B2 JPS6147511 B2 JP S6147511B2 JP 53091044 A JP53091044 A JP 53091044A JP 9104478 A JP9104478 A JP 9104478A JP S6147511 B2 JPS6147511 B2 JP S6147511B2
Authority
JP
Japan
Prior art keywords
kallikrein
amino
benzamidine
buffer
add
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53091044A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5517364A (en
Inventor
Setsuo Fujii
Akio Yokoshima
Kyoaki Noda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toho Pharmaceutical Industries Co Ltd
Original Assignee
Toho Pharmaceutical Industries Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toho Pharmaceutical Industries Co Ltd filed Critical Toho Pharmaceutical Industries Co Ltd
Priority to JP9104478A priority Critical patent/JPS5517364A/ja
Priority to DE19792925681 priority patent/DE2925681A1/de
Priority to US06/058,292 priority patent/US4252902A/en
Publication of JPS5517364A publication Critical patent/JPS5517364A/ja
Publication of JPS6147511B2 publication Critical patent/JPS6147511B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP9104478A 1978-07-25 1978-07-25 Purification of pancreatic kallikrein Granted JPS5517364A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP9104478A JPS5517364A (en) 1978-07-25 1978-07-25 Purification of pancreatic kallikrein
DE19792925681 DE2925681A1 (de) 1978-07-25 1979-06-26 Verfahren zur reinigung von rohem kallikrein
US06/058,292 US4252902A (en) 1978-07-25 1979-07-17 Process for purification of crude kallikrein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9104478A JPS5517364A (en) 1978-07-25 1978-07-25 Purification of pancreatic kallikrein

Publications (2)

Publication Number Publication Date
JPS5517364A JPS5517364A (en) 1980-02-06
JPS6147511B2 true JPS6147511B2 (en, 2012) 1986-10-20

Family

ID=14015495

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9104478A Granted JPS5517364A (en) 1978-07-25 1978-07-25 Purification of pancreatic kallikrein

Country Status (3)

Country Link
US (1) US4252902A (en, 2012)
JP (1) JPS5517364A (en, 2012)
DE (1) DE2925681A1 (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01117110U (en, 2012) * 1988-01-30 1989-08-08

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335203A (en) * 1980-07-10 1982-06-15 The Regents Of The University Of California Method for identifying potential contrast media reactors
DE3103257A1 (de) * 1981-01-31 1982-08-26 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung des hochreinen enzyms kallikrein aus schweinepankreas-extrakten
US4461833A (en) * 1982-06-23 1984-07-24 University Patents, Inc. Chromatographically purifying proteolytic procoagulant enzyme from animal tissue extract
JPS59137417A (ja) * 1983-01-28 1984-08-07 Morinaga Milk Ind Co Ltd 人尿由来コロニ−形成刺激因子及びカリクレインの製造法
US4568488A (en) * 1984-01-11 1986-02-04 Lee Huang Sylvia Reverse immunoaffinity chromatography purification method
JPH0662435B2 (ja) * 1986-02-28 1994-08-17 株式会社ミドリ十字 免疫グロブリンの製造方法
JPS6485077A (en) * 1987-09-25 1989-03-30 Takara Shuzo Co Purification of arginine residue-specific endopeptidase
CN101134952B (zh) * 2007-07-02 2011-02-09 广东天普生化医药股份有限公司 一种人尿激肽原酶及其制备方法
CN101134953B (zh) * 2007-07-02 2011-02-09 广东天普生化医药股份有限公司 重组人胰激肽原酶

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1102973B (de) * 1960-03-25 1961-03-23 Bayer Ag Verfahren zur Herstellung von hoch gereinigten Kallikrein-Praeparaten
US3746622A (en) * 1971-05-12 1973-07-17 Xerox Corp Composition and process
US4020268A (en) * 1972-11-13 1977-04-26 Xerox Corporation Agarose containing affinity matrix materials
US3912595A (en) * 1974-02-25 1975-10-14 Us Health Method of purifying enzymes using boronic acids covalently bonded to an insoluble support
JPS5820592B2 (ja) * 1975-08-02 1983-04-23 アマノセイヤク カブシキガイシヤ カリクレインノセイセイホウホウ
GB1522359A (en) * 1975-12-05 1978-08-23 Seikagaku Kogyo Co Ltd Purifying kallidinogenase
US4064010A (en) * 1976-07-21 1977-12-20 Eastman Kodak Company Purification of uricase

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01117110U (en, 2012) * 1988-01-30 1989-08-08

Also Published As

Publication number Publication date
US4252902A (en) 1981-02-24
DE2925681A1 (de) 1980-02-07
JPS5517364A (en) 1980-02-06

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