JPS61213671A - ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法 - Google Patents

ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法

Info

Publication number
JPS61213671A
JPS61213671A JP5420885A JP5420885A JPS61213671A JP S61213671 A JPS61213671 A JP S61213671A JP 5420885 A JP5420885 A JP 5420885A JP 5420885 A JP5420885 A JP 5420885A JP S61213671 A JPS61213671 A JP S61213671A
Authority
JP
Japan
Prior art keywords
plasmin
antibody
human
alpha2
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5420885A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0535827B2 (esLanguage
Inventor
Yoshihiko Washimi
芳彦 鷲見
Yukiya Koike
小池　行也
Yataro Ichikawa
市川　弥太郎
Nobuhiko Yoshida
信彦 吉田
Nobuo Aoki
青木　延雄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP5420885A priority Critical patent/JPS61213671A/ja
Priority to EP19850109227 priority patent/EP0169549B1/en
Priority to DE19853586577 priority patent/DE3586577T2/de
Priority to DK339985A priority patent/DK339985A/da
Publication of JPS61213671A publication Critical patent/JPS61213671A/ja
Publication of JPH0535827B2 publication Critical patent/JPH0535827B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP5420885A 1984-07-26 1985-03-20 ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法 Granted JPS61213671A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP5420885A JPS61213671A (ja) 1985-03-20 1985-03-20 ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法
EP19850109227 EP0169549B1 (en) 1984-07-26 1985-07-23 Immunological determination of human plasmin/alpha2-plasmin inhibitor
DE19853586577 DE3586577T2 (de) 1984-07-26 1985-07-23 Immunologische bestimmung von menschlichem plasmin/alpha-2-plasmin-hemmstoff.
DK339985A DK339985A (da) 1984-07-26 1985-07-25 Immunologisk bestemmelse af humanplasmin/alfa2-plasmininhibitor samt reagenssystem til brug herved

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5420885A JPS61213671A (ja) 1985-03-20 1985-03-20 ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法

Publications (2)

Publication Number Publication Date
JPS61213671A true JPS61213671A (ja) 1986-09-22
JPH0535827B2 JPH0535827B2 (esLanguage) 1993-05-27

Family

ID=12964132

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5420885A Granted JPS61213671A (ja) 1984-07-26 1985-03-20 ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法

Country Status (1)

Country Link
JP (1) JPS61213671A (esLanguage)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63247661A (ja) * 1987-04-02 1988-10-14 Nisshin Flour Milling Co Ltd アミラ−ゼインヒビタ−の定量方法
WO1992011384A1 (fr) * 1990-12-20 1992-07-09 Iatron Laboratories, Inc. ANTICORPS DIRIGES CONTRE LE COMPLEXE INHIBITEUR DE PLASMINE-α2-PLASMINE HUMAIN, HYBRIDOME ET DOSAGE IMMUNOLOGIQUE
JPH06300757A (ja) * 1993-04-12 1994-10-28 Fuji Yakuhin Kogyo Kk ヒト間質型コラゲナーゼと阻害剤との複合体の免疫学的定量法および臨床診断への応用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5356308A (en) * 1976-03-18 1978-05-22 Leuven Res & Dev Vzw Antiplasmin and its antiserum
JPS5665896A (en) * 1979-10-31 1981-06-03 Mochida Pharmaceut Co Ltd Preparation of alpha2-plasmin inhibitor
JPS5716355A (en) * 1980-04-25 1982-01-27 Hoffmann La Roche Immunological method
JPS57136165A (en) * 1981-02-18 1982-08-23 Mochida Pharmaceut Co Ltd Immunological measuring reagent
JPS5954966A (ja) * 1982-09-22 1984-03-29 Mochida Pharmaceut Co Ltd 免疫学的測定試薬

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5356308A (en) * 1976-03-18 1978-05-22 Leuven Res & Dev Vzw Antiplasmin and its antiserum
JPS5665896A (en) * 1979-10-31 1981-06-03 Mochida Pharmaceut Co Ltd Preparation of alpha2-plasmin inhibitor
JPS5716355A (en) * 1980-04-25 1982-01-27 Hoffmann La Roche Immunological method
JPS57136165A (en) * 1981-02-18 1982-08-23 Mochida Pharmaceut Co Ltd Immunological measuring reagent
JPS5954966A (ja) * 1982-09-22 1984-03-29 Mochida Pharmaceut Co Ltd 免疫学的測定試薬

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63247661A (ja) * 1987-04-02 1988-10-14 Nisshin Flour Milling Co Ltd アミラ−ゼインヒビタ−の定量方法
WO1992011384A1 (fr) * 1990-12-20 1992-07-09 Iatron Laboratories, Inc. ANTICORPS DIRIGES CONTRE LE COMPLEXE INHIBITEUR DE PLASMINE-α2-PLASMINE HUMAIN, HYBRIDOME ET DOSAGE IMMUNOLOGIQUE
JPH06300757A (ja) * 1993-04-12 1994-10-28 Fuji Yakuhin Kogyo Kk ヒト間質型コラゲナーゼと阻害剤との複合体の免疫学的定量法および臨床診断への応用

Also Published As

Publication number Publication date
JPH0535827B2 (esLanguage) 1993-05-27

Similar Documents

Publication Publication Date Title
US5855886A (en) Antibodies, and methods for their use
JP5807300B2 (ja) 試料中のｃ反応性蛋白質の測定方法及び測定試薬
JPH0720127A (ja) 各種ｐｉｖｋａの測定方法および測定試薬
JP3517754B2 (ja) 抗ヒト可溶性フィブリン抗体，ハイブリドーマ及び免疫学的測定法
KR20170132310A (ko) 트롬빈 안티트롬빈 복합체의 측정 시약 및 측정 방법
JP2012082210A (ja) Ａｄａｍｔｓ１３活性検定用抗体及び活性検定方法
JPS61213671A (ja) ヒトプラスミン−α↓２−プラスミンインヒビタ−複合体の測定法
JPH04507285A (ja) 抗イディオトープ免疫検定法
EP0339302A1 (en) Reagent system for immunologically assaying complex of human plasminogen activator inhibitor and human tissue plasminogen activator, and assay kit therefor
JP3888695B2 (ja) ヒトｌｅｃｔ２に対する抗体、それを産生する細胞、その測定法及び測定用キット
JP2518602B2 (ja) ヒトプロテインｓに対するモノクロ―ナル抗体を用いた免疫学的測定試薬及びキット
JPH07508103A (ja) トロンビン−アンチトロンビン３複合体のためのイムノアッセイ及び試験キット
US7541159B2 (en) Molecular-specific urokinase antibodies
JP2507317B2 (ja) プラスミン―α２プラスミンインヒビタ―複合体の測定方法
EP0169549A2 (en) Immunological determination of human plasmin/alpha2-plasmin inhibitor
JPS61213670A (ja) ヒトα↓２−プラスミンインヒビタ−の測定方法
JPS61286753A (ja) モノクロ−ナル抗体を用いた免疫学的測定方法およびそのためのキツト
JPH07117534B2 (ja) ヒトプロテインｓに対するモノクローナル抗体を用いた免疫学的測定試薬及びキット
JPS6265693A (ja) 活性型ヒト血液凝固第▲ｘｉ▼因子の免疫学的定量法
JPS6134465A (ja) ヒトα↓２−プラスミンインヒビタ−に対するモノクロ−ナル抗体を用いた免疫学的測定試薬及びキツト
JP2003004748A (ja) 膵臓癌診断用試薬
JPS60231168A (ja) ヒトα２―プラスミンインヒビターに対するモノクローナル抗体を用いた免疫学的測定試薬及びキット
JPH07117535B2 (ja) ヒトプロテインｓに免疫学的測定方法、それに用いる測定試薬及びキット
EP0251186A2 (en) Monoclonal antibody to human plasminogen, method for production thereof, assay reagent and kit comprising said antibody, and hybridoma producing said antibody
JP2002112768A (ja) アンジオスタチン特異的モノクローナル抗体、及びこのモノクローナル抗体を用いたアンジオスタチンの検出方法等

Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term