JPS6036061A - 血液浄化装置 - Google Patents
血液浄化装置Info
- Publication number
- JPS6036061A JPS6036061A JP58145590A JP14559083A JPS6036061A JP S6036061 A JPS6036061 A JP S6036061A JP 58145590 A JP58145590 A JP 58145590A JP 14559083 A JP14559083 A JP 14559083A JP S6036061 A JPS6036061 A JP S6036061A
- Authority
- JP
- Japan
- Prior art keywords
- blood
- plasma
- purified
- outlet
- inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004369 blood Anatomy 0.000 title claims description 94
- 239000008280 blood Substances 0.000 title claims description 94
- 239000012510 hollow fiber Substances 0.000 claims description 40
- 238000000746 purification Methods 0.000 claims description 31
- 230000017531 blood circulation Effects 0.000 claims description 16
- 210000000601 blood cell Anatomy 0.000 claims description 9
- 238000000926 separation method Methods 0.000 claims description 7
- 238000005192 partition Methods 0.000 claims description 6
- 230000035699 permeability Effects 0.000 claims description 6
- 239000011148 porous material Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 description 92
- 238000000034 method Methods 0.000 description 15
- 239000012629 purifying agent Substances 0.000 description 14
- 230000004087 circulation Effects 0.000 description 11
- 239000000126 substance Substances 0.000 description 10
- 238000010586 diagram Methods 0.000 description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 6
- 238000000605 extraction Methods 0.000 description 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 239000003566 sealing material Substances 0.000 description 4
- 206010018910 Haemolysis Diseases 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 239000010419 fine particle Substances 0.000 description 3
- 230000008588 hemolysis Effects 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000002504 physiological saline solution Substances 0.000 description 3
- 229920002492 poly(sulfone) Polymers 0.000 description 3
- 229920000515 polycarbonate Polymers 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 108010093096 Immobilized Enzymes Proteins 0.000 description 1
- 238000008214 LDL Cholesterol Methods 0.000 description 1
- 102000007330 LDL Lipoproteins Human genes 0.000 description 1
- 108010007622 LDL Lipoproteins Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 229920003045 dextran sodium sulfate Polymers 0.000 description 1
- 229960000633 dextran sulfate Drugs 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 239000011152 fibreglass Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000002616 plasmapheresis Methods 0.000 description 1
- 229920002239 polyacrylonitrile Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000010615 ring circuit Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/342—Adding solutions to the blood, e.g. substitution solutions
- A61M1/3424—Substitution fluid path
- A61M1/3427—Substitution fluid path back through the membrane, e.g. by inverted trans-membrane pressure [TMP]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/342—Adding solutions to the blood, e.g. substitution solutions
- A61M1/3455—Substitution fluids
- A61M1/3468—Substitution fluids using treated filtrate as substitution fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0456—Lipoprotein
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58145590A JPS6036061A (ja) | 1983-08-08 | 1983-08-08 | 血液浄化装置 |
| CA000460414A CA1247016A (en) | 1983-08-08 | 1984-08-03 | Apparatus for purifying blood |
| EP84109270A EP0143178A1 (en) | 1983-08-08 | 1984-08-04 | Apparatus for purifying blood |
| US06/638,084 US4609461A (en) | 1983-08-08 | 1984-08-06 | Apparatus for purifying blood |
| NZ209141A NZ209141A (en) | 1983-08-08 | 1984-08-07 | Blood purification: plasma separated from blood and purified |
| ES534935A ES534935A0 (es) | 1983-08-08 | 1984-08-07 | Un aparato para la purificacion de sangre |
| AU31681/84A AU570601B2 (en) | 1983-08-08 | 1984-08-07 | Puriifying blood and plasma |
| ZA846135A ZA846135B (en) | 1983-08-08 | 1984-08-08 | Apparatus for purifying blood |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58145590A JPS6036061A (ja) | 1983-08-08 | 1983-08-08 | 血液浄化装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6036061A true JPS6036061A (ja) | 1985-02-25 |
| JPH0261265B2 JPH0261265B2 (en, 2012) | 1990-12-19 |
Family
ID=15388599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58145590A Granted JPS6036061A (ja) | 1983-08-08 | 1983-08-08 | 血液浄化装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4609461A (en, 2012) |
| EP (1) | EP0143178A1 (en, 2012) |
| JP (1) | JPS6036061A (en, 2012) |
| AU (1) | AU570601B2 (en, 2012) |
| CA (1) | CA1247016A (en, 2012) |
| ES (1) | ES534935A0 (en, 2012) |
| NZ (1) | NZ209141A (en, 2012) |
| ZA (1) | ZA846135B (en, 2012) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63311962A (ja) * | 1987-06-15 | 1988-12-20 | Terumo Corp | 白血球捕捉分離器具 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6045359A (ja) * | 1983-08-19 | 1985-03-11 | 鐘淵化学工業株式会社 | 血液浄化器 |
| US5370802A (en) * | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
| US5656163A (en) * | 1987-01-30 | 1997-08-12 | Baxter International Inc. | Chamber for use in a rotating field to separate blood components |
| US5792372A (en) * | 1987-01-30 | 1998-08-11 | Baxter International, Inc. | Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma |
| US5690835A (en) * | 1991-12-23 | 1997-11-25 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
| US6007725A (en) * | 1991-12-23 | 1999-12-28 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
| US5549834A (en) * | 1991-12-23 | 1996-08-27 | Baxter International Inc. | Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes |
| US5427695A (en) * | 1993-07-26 | 1995-06-27 | Baxter International Inc. | Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate |
| ATA159993A (de) * | 1993-08-10 | 1995-09-15 | Dieter Dr Falkenhagen | Anordnung zur elimination von substanzen aus flüssigkeiten |
| US6186146B1 (en) | 1996-08-30 | 2001-02-13 | Delcath Systems Inc | Cancer treatment method |
| JPH1076004A (ja) * | 1996-09-05 | 1998-03-24 | Kanegafuchi Chem Ind Co Ltd | 体液処理用吸着材及び体液処理用吸着器 |
| US5919163A (en) * | 1997-07-14 | 1999-07-06 | Delcath Systems, Inc. | Catheter with slidable balloon |
| US5817046A (en) * | 1997-07-14 | 1998-10-06 | Delcath Systems, Inc. | Apparatus and method for isolated pelvic perfusion |
| US6099730A (en) * | 1997-11-14 | 2000-08-08 | Massachusetts Institute Of Technology | Apparatus for treating whole blood comprising concentric cylinders defining an annulus therebetween |
| US6497675B1 (en) * | 2000-04-17 | 2002-12-24 | Renal Tech International Llc | Device for extracorporeal treatment of physiological fluids of organism |
| US8202240B2 (en) * | 2008-08-12 | 2012-06-19 | Caridianbct, Inc. | System and method for collecting plasma protein fractions from separated blood components |
| US8123713B2 (en) * | 2008-08-12 | 2012-02-28 | Caridian Bct, Inc. | System and method for collecting plasma protein fractions from separated blood components |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE123476C (en, 2012) * | 1960-09-19 | |||
| US3669878A (en) * | 1968-12-02 | 1972-06-13 | Health Education And Welfare U | Treatment of dialysate solution for removal of urea |
| GB1558370A (en) * | 1975-09-26 | 1979-12-28 | Asahi Chemical Ind | Blood treating apparatus |
| CA1153171A (en) * | 1979-12-17 | 1983-09-06 | David T. Chen | Cellulose semipermeable hollow fibers and method for making same |
| DE3101159C2 (de) * | 1981-01-16 | 1985-08-22 | Udipi Ramakrishna Dr. 5100 Aachen Shettigar | Verfahren zur Reinigung von Blut und künstliche Niere zur Durchführung des Verfahrens |
| DD206076A1 (de) * | 1981-09-28 | 1984-01-18 | Univ Leipzig | Verfahren zur blutreinigung |
| SE425216B (sv) * | 1981-10-05 | 1982-09-13 | Gambro Ab | Filtreranordning |
| JPS5886172A (ja) * | 1981-11-18 | 1983-05-23 | テルモ株式会社 | 医用物質移動装置 |
-
1983
- 1983-08-08 JP JP58145590A patent/JPS6036061A/ja active Granted
-
1984
- 1984-08-03 CA CA000460414A patent/CA1247016A/en not_active Expired
- 1984-08-04 EP EP84109270A patent/EP0143178A1/en not_active Withdrawn
- 1984-08-06 US US06/638,084 patent/US4609461A/en not_active Expired - Lifetime
- 1984-08-07 ES ES534935A patent/ES534935A0/es active Granted
- 1984-08-07 NZ NZ209141A patent/NZ209141A/en unknown
- 1984-08-07 AU AU31681/84A patent/AU570601B2/en not_active Ceased
- 1984-08-08 ZA ZA846135A patent/ZA846135B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63311962A (ja) * | 1987-06-15 | 1988-12-20 | Terumo Corp | 白血球捕捉分離器具 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES8600945A1 (es) | 1985-10-16 |
| NZ209141A (en) | 1987-06-30 |
| CA1247016A (en) | 1988-12-20 |
| JPH0261265B2 (en, 2012) | 1990-12-19 |
| US4609461A (en) | 1986-09-02 |
| ZA846135B (en) | 1985-04-24 |
| ES534935A0 (es) | 1985-10-16 |
| EP0143178A1 (en) | 1985-06-05 |
| AU570601B2 (en) | 1988-03-17 |
| AU3168184A (en) | 1985-02-14 |
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