JPS60204786A - （６ｒ）―テトラヒドロビオプテリンの合成法 - Google Patents

（６ｒ）―テトラヒドロビオプテリンの合成法

Info

Publication number
JPS60204786A
JPS60204786A JP59061665A JP6166584A JPS60204786A JP S60204786 A JPS60204786 A JP S60204786A JP 59061665 A JP59061665 A JP 59061665A JP 6166584 A JP6166584 A JP 6166584A JP S60204786 A JPS60204786 A JP S60204786A
Authority
JP
Japan
Prior art keywords
amino
hydroxy
synthesis method
pteridine
dihydrogen phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59061665A
Other languages
English (en)
Japanese (ja)
Other versions
JPH047747B2 (enrdf_load_stackoverflow
Inventor
Sadao Matsuura
松浦　貞郎
Takashi Sugimoto
隆 杉本
Shizuaki Murata
静昭 村田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagoya University NUC
Original Assignee
Nagoya University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagoya University NUC filed Critical Nagoya University NUC
Priority to JP59061665A priority Critical patent/JPS60204786A/ja
Publication of JPS60204786A publication Critical patent/JPS60204786A/ja
Publication of JPH047747B2 publication Critical patent/JPH047747B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP59061665A 1984-03-29 1984-03-29 （６ｒ）―テトラヒドロビオプテリンの合成法 Granted JPS60204786A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP59061665A JPS60204786A (ja) 1984-03-29 1984-03-29 （６ｒ）―テトラヒドロビオプテリンの合成法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59061665A JPS60204786A (ja) 1984-03-29 1984-03-29 （６ｒ）―テトラヒドロビオプテリンの合成法

Publications (2)

Publication Number Publication Date
JPS60204786A true JPS60204786A (ja) 1985-10-16
JPH047747B2 JPH047747B2 (enrdf_load_stackoverflow) 1992-02-12

Family

ID=13177749

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59061665A Granted JPS60204786A (ja) 1984-03-29 1984-03-29 （６ｒ）―テトラヒドロビオプテリンの合成法

Country Status (1)

Country Link
JP (1) JPS60204786A (enrdf_load_stackoverflow)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01234739A (ja) * 1988-03-15 1989-09-20 Fujitsu Ltd 気流水平垂直両用クリーンベンチ
US4937342A (en) * 1987-11-30 1990-06-26 Kabushiki Kaisha Vitamin Kenkyusyo Intermediates for synthesizing BH4 and its derivatives
JP2001302665A (ja) * 2000-04-19 2001-10-31 Shiratori Pharmaceutical Co Ltd Ｌ−ビオプテリン又はｄ−ネオプテリンの製造法
JP2007536210A (ja) * 2003-11-17 2007-12-13 メルック・エプロバ・アクチエンゲゼルシヤフト （６ｒ）−ｌ−エリスロ−テトラヒドロビオプテリンジヒドロクロライドの結晶形
US7566714B2 (en) 2003-11-17 2009-07-28 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of metabolic disorders
WO2012048451A1 (zh) * 2010-10-13 2012-04-19 因华生技制药股份有限公司 (6r)-四氢生物喋呤盐酸盐的制备方法
WO2013152609A1 (zh) * 2012-04-10 2013-10-17 凯莱英医药集团（天津）股份有限公司 一种二盐酸沙丙蝶呤的合成方法
WO2013152608A1 (zh) * 2012-04-10 2013-10-17 凯莱英医药集团（天津）股份有限公司 一种二盐酸沙丙喋呤的合成方法
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60178887A (ja) * 1984-02-23 1985-09-12 Kanegafuchi Chem Ind Co Ltd ５，６，７，８−テトラヒドロ−ｌ−ビオプテリンの製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60178887A (ja) * 1984-02-23 1985-09-12 Kanegafuchi Chem Ind Co Ltd ５，６，７，８−テトラヒドロ−ｌ−ビオプテリンの製造法

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937342A (en) * 1987-11-30 1990-06-26 Kabushiki Kaisha Vitamin Kenkyusyo Intermediates for synthesizing BH4 and its derivatives
JPH01234739A (ja) * 1988-03-15 1989-09-20 Fujitsu Ltd 気流水平垂直両用クリーンベンチ
JP2001302665A (ja) * 2000-04-19 2001-10-31 Shiratori Pharmaceutical Co Ltd Ｌ−ビオプテリン又はｄ−ネオプテリンの製造法
US9433624B2 (en) 2003-11-17 2016-09-06 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of metabolic disorders
US7566714B2 (en) 2003-11-17 2009-07-28 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of metabolic disorders
JP2011162568A (ja) * 2003-11-17 2011-08-25 Merck Eprova Ag （６ｒ）−ｌ−エリスロ−テトラヒドロビオプテリンジヒドロクロライドの結晶形
US9993481B2 (en) 2003-11-17 2018-06-12 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of metabolic disorders
JP2007536210A (ja) * 2003-11-17 2007-12-13 メルック・エプロバ・アクチエンゲゼルシヤフト （６ｒ）−ｌ−エリスロ−テトラヒドロビオプテリンジヒドロクロライドの結晶形
WO2012048451A1 (zh) * 2010-10-13 2012-04-19 因华生技制药股份有限公司 (6r)-四氢生物喋呤盐酸盐的制备方法
CN102443006A (zh) * 2010-10-13 2012-05-09 因华生技制药股份有限公司 (6r)-四氢生物喋呤盐酸盐的制备方法
CN102443006B (zh) * 2010-10-13 2016-02-24 因华生技制药股份有限公司 (6r)-四氢生物喋呤盐酸盐的制备方法
JP2013540768A (ja) * 2010-10-13 2013-11-07 イノファーマックス インコーポレイテッド （６ｒ）−テトラヒドロビオプテリン塩酸塩の製造方法
US8895735B2 (en) 2010-10-13 2014-11-25 Innopharmax, Inc. Preparation process of (6R)-tetrahydrobiopterin hydrochloride
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
US9365573B2 (en) 2012-04-10 2016-06-14 Asymchem Laboratories (Tianjin) Co., Ltd Method for synthesizing sapropterin dihydrochloride
US9371326B2 (en) 2012-04-10 2016-06-21 Asymchem Laboratories (Tianjin) Co., Ltd Method for synthesizing sapropterin dihydrochloride
WO2013152608A1 (zh) * 2012-04-10 2013-10-17 凯莱英医药集团（天津）股份有限公司 一种二盐酸沙丙喋呤的合成方法
WO2013152609A1 (zh) * 2012-04-10 2013-10-17 凯莱英医药集团（天津）股份有限公司 一种二盐酸沙丙蝶呤的合成方法

Also Published As

Publication number Publication date
JPH047747B2 (enrdf_load_stackoverflow) 1992-02-12

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