JPS60192703A - 少なくとも1個の遊離ホルミル基を有する高分子化合物 - Google Patents

少なくとも1個の遊離ホルミル基を有する高分子化合物

Info

Publication number
JPS60192703A
JPS60192703A JP59258138A JP25813884A JPS60192703A JP S60192703 A JPS60192703 A JP S60192703A JP 59258138 A JP59258138 A JP 59258138A JP 25813884 A JP25813884 A JP 25813884A JP S60192703 A JPS60192703 A JP S60192703A
Authority
JP
Japan
Prior art keywords
conjugate
polymer compound
physiologically active
compound
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59258138A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6353201B2 (OSRAM
Inventor
Hiroyoshi Takahashi
啓悦 高橋
Nobuo Ueda
上田 信夫
Masaaki Hazue
葉杖 正昭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON MEJIFUIJITSUKUSU KK
Nihon Medi Physics Co Ltd
Original Assignee
NIPPON MEJIFUIJITSUKUSU KK
Nihon Medi Physics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/558,333 external-priority patent/US4666697A/en
Application filed by NIPPON MEJIFUIJITSUKUSU KK, Nihon Medi Physics Co Ltd filed Critical NIPPON MEJIFUIJITSUKUSU KK
Publication of JPS60192703A publication Critical patent/JPS60192703A/ja
Publication of JPS6353201B2 publication Critical patent/JPS6353201B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP59258138A 1983-12-05 1984-12-05 少なくとも1個の遊離ホルミル基を有する高分子化合物 Granted JPS60192703A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/558,333 US4666697A (en) 1982-12-08 1983-12-05 Radioactive diagnostic agent
US558333 1995-11-15

Publications (2)

Publication Number Publication Date
JPS60192703A true JPS60192703A (ja) 1985-10-01
JPS6353201B2 JPS6353201B2 (OSRAM) 1988-10-21

Family

ID=24229141

Family Applications (3)

Application Number Title Priority Date Filing Date
JP59258138A Granted JPS60192703A (ja) 1983-12-05 1984-12-05 少なくとも1個の遊離ホルミル基を有する高分子化合物
JP59258139A Granted JPS60186502A (ja) 1983-12-05 1984-12-05 放射性医薬品とその調製用高分子化合物
JP62268981A Granted JPS63225601A (ja) 1983-12-05 1987-10-24 放射性医薬品調製用高分子化合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP59258139A Granted JPS60186502A (ja) 1983-12-05 1984-12-05 放射性医薬品とその調製用高分子化合物
JP62268981A Granted JPS63225601A (ja) 1983-12-05 1987-10-24 放射性医薬品調製用高分子化合物

Country Status (1)

Country Link
JP (3) JPS60192703A (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
US5672334A (en) * 1991-01-16 1997-09-30 Access Pharmaceuticals, Inc. Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
WO2013049622A1 (en) 2011-09-28 2013-04-04 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced ms signals
US10436790B2 (en) 2011-09-28 2019-10-08 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
US11352325B2 (en) 2011-09-28 2022-06-07 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
JP6099055B2 (ja) * 2014-05-09 2017-03-22 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 変性病変の診断のためのリガンドとしてのフコイダン
JP7055634B2 (ja) 2014-10-30 2022-04-18 ウオーターズ・テクノロジーズ・コーポレイシヨン 標識化グリコシルアミンの迅速調製およびそれを生成するグリコシル化生体分子の分析方法
EP3744708B1 (en) * 2014-11-13 2023-08-09 Waters Technologies Corporation Calibrant for liquid chromatography calibration of labeled n-glycans
EP4234062A3 (en) 2016-06-21 2023-10-25 Waters Technologies Corporation Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties
EP3472132A4 (en) 2016-06-21 2020-01-15 Waters Technologies Corporation FLUORESCENCE LABELING OF GLYCANS AND OTHER BIOMOLECULES BY REDUCING AMINATION FOR IMPROVED MASS SPECTROMETRY SIGNALS
WO2018005139A1 (en) 2016-07-01 2018-01-04 Waters Technologies Corporation Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation

Also Published As

Publication number Publication date
JPS6353201B2 (OSRAM) 1988-10-21
JPS60186502A (ja) 1985-09-24
JPH0548761B2 (OSRAM) 1993-07-22
JPS63225601A (ja) 1988-09-20
JPS641449B2 (OSRAM) 1989-01-11

Similar Documents

Publication Publication Date Title
EP0233619B1 (en) High molecular compounds having amino groups, and their utilization
CA1177072A (en) Diagnostic radio-labeled polysaccharide derivatives
EP0279307B2 (en) Bifunctional chelating agents
US5032678A (en) Radio labeled high molecular compound comprising unit of asialoglycoprotein acceptor-directing compound and unit of chelate forming compound chemically bonded thereto
EP0035765B1 (en) A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound
US5384401A (en) Chemical product usable as a non-radioactive carrier
JPH07506086A (ja) 撮像用テクネチウム−99m標識ペプチド
JPS60192703A (ja) 少なくとも1個の遊離ホルミル基を有する高分子化合物
JP2792871B2 (ja) 金属イオンの除去方法およびそれに用いる溶液
JPH0233692B2 (OSRAM)
EP0054920A1 (en) 3-Aminomethylene-2,4-pentanedione bis(thiosemicarbazone) derivatives, and their production and use
US4431626A (en) Tc-99m Labeled carrier for imaging
US4559221A (en) P-Glyoxyloylphenylalkanoic acid bis(thiosemicarbazone) derivatives, and their production and use
JP2548711B2 (ja) アミノ基と2官能性配位子を有する反応性高分子化合物とその利用
JPH0421682B2 (OSRAM)
JPS59105002A (ja) 反応性高分子化合物
JPS63170400A (ja) 放射性医薬品とその調製用高分子化合物
JPH0414084B2 (OSRAM)
JPS59106425A (ja) 高分子化合物含有放射性診断剤
CA1258851A (en) Chemical product useful as a non-radioactive carrier
JPH0759524B2 (ja) 放射性医薬品とその調製用高分子化合物
JPS63170399A (ja) 放射性医薬品とその調製用高分子化合物
Paik et al. Comparison of tc-99m and in-111 labeling of DTPA conjugated antibodies
JPH08253581A (ja) 生理活性物質結合高分子化合物および当該化合物を含む放射性医薬品調製用キャリアー
JPH0416465B2 (OSRAM)