JPS5899499A - ５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤 - Google Patents

５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤

Info

Publication number
JPS5899499A
JPS5899499A JP56196939A JP19693981A JPS5899499A JP S5899499 A JPS5899499 A JP S5899499A JP 56196939 A JP56196939 A JP 56196939A JP 19693981 A JP19693981 A JP 19693981A JP S5899499 A JPS5899499 A JP S5899499A
Authority
JP
Japan
Prior art keywords
group
water
fluoro
deoxyuridine
butanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56196939A
Other languages
English (en)
Japanese (ja)
Other versions
JPS634810B2 (esLanguage
Inventor
Kenzo Watanabe
兼三 渡辺
Yoshinori Kato
加藤　喜規
Masahiko Saito
斉藤　政彦
Takeo Oba
大場　丈夫
Hisashi Fukushima
福島　久
Takeshi Hara
健 原
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP56196939A priority Critical patent/JPS5899499A/ja
Priority to EP82306541A priority patent/EP0081386B1/en
Priority to DE8282306541T priority patent/DE3263939D1/de
Priority to US06/448,087 priority patent/US4605645A/en
Publication of JPS5899499A publication Critical patent/JPS5899499A/ja
Publication of JPS634810B2 publication Critical patent/JPS634810B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56196939A 1981-12-09 1981-12-09 ５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤 Granted JPS5899499A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP56196939A JPS5899499A (ja) 1981-12-09 1981-12-09 ５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤
EP82306541A EP0081386B1 (en) 1981-12-09 1982-12-08 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
DE8282306541T DE3263939D1 (en) 1981-12-09 1982-12-08 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
US06/448,087 US4605645A (en) 1981-12-09 1982-12-09 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56196939A JPS5899499A (ja) 1981-12-09 1981-12-09 ５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤

Publications (2)

Publication Number Publication Date
JPS5899499A true JPS5899499A (ja) 1983-06-13
JPS634810B2 JPS634810B2 (esLanguage) 1988-02-01

Family

ID=16366161

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56196939A Granted JPS5899499A (ja) 1981-12-09 1981-12-09 ５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤

Country Status (1)

Country Link
JP (1) JPS5899499A (esLanguage)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5993096A (ja) * 1982-11-19 1984-05-29 Teijin Ltd ５−フルオロ−２′−デオキシウリジン誘導体及びその製造法
US5032680A (en) * 1988-02-29 1991-07-16 Kuraray Co., Ltd. 2'-deoxy-5-fluorouridine derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52139082A (en) * 1976-05-07 1977-11-19 Mitsui Toatsu Chem Inc 5-fluorouridinephosphates
JPS5329938A (en) * 1976-08-27 1978-03-20 Mitsui Toatsu Chem Inc Carcinostatic agent

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52139082A (en) * 1976-05-07 1977-11-19 Mitsui Toatsu Chem Inc 5-fluorouridinephosphates
JPS5329938A (en) * 1976-08-27 1978-03-20 Mitsui Toatsu Chem Inc Carcinostatic agent

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5993096A (ja) * 1982-11-19 1984-05-29 Teijin Ltd ５−フルオロ−２′−デオキシウリジン誘導体及びその製造法
US5032680A (en) * 1988-02-29 1991-07-16 Kuraray Co., Ltd. 2'-deoxy-5-fluorouridine derivatives

Also Published As

Publication number Publication date
JPS634810B2 (esLanguage) 1988-02-01

Similar Documents

Publication Publication Date Title
US5233031A (en) Phosphoramidate analogs of 2'-deoxyuridine
EP0151189B1 (en) Antineoplastic agent
US4395406A (en) 5-Halopyrimid-2-ones
US4605645A (en) 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
US4490529A (en) Cysteic acid and homocysteic acid analogues of methotrexate and aminopterin
PL89967B1 (esLanguage)
EP0129984B1 (en) Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same
Shealy et al. Synthesis and antiviral activity of the carbocyclic analogs of 5-ethyl-2'-deoxyuridine and of 5-ethynyl-2'-deoxyuridine
US4542021A (en) Antitumor compositions for non-injection administration
EP0683788B1 (en) 3'-aziridino-anthracycline derivatives
US4239905A (en) 1-β-D-Arabinofuranosylcytosine-5'-oleyl phosphate and salts thereof
US4367332A (en) N4 -Alkoxycarbonylarabinofuranosylcytosine
JPS5899499A (ja) ５−フルオロ−２′−デオキシウリジン誘導体を有効成分とする抗腫瘍剤
JPH0136838B2 (esLanguage)
US4751293A (en) Process for preparation of N6 -substituted 3',5'-cyclic adenosine monophosphate and salt thereof
EP0566162B1 (en) 2'-Methylidenepyrimidine Nucleoside Compounds, their use and method for production thereof
JPS60193997A (ja) 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法
JPS58192899A (ja) ３′−アシル−５−フルオロ−２′−デオキシウリジン誘導体及びその製造法
JPS6058997A (ja) ４’−ハロ−アントラサイクリングリコシド類
US5401726A (en) 2'methylidenepyrimidine nucleoside compounds, their use and method for production thereof
JP2665527B2 (ja) ２’−デオキシ−２’−メチリデンピリミジンヌクレオチド化合物
JP3074341B2 (ja) ２’−デオキシ−５−フルオロウリジン誘導体
JPS636080B2 (esLanguage)
EP0378706A1 (en) 5-substituted uridine derivatives and intermediates for their preparation
JPS60228497A (ja) 新規なアデニル酸誘導体