JPS5892681A - 新規なトリアゾロキナゾリン，その製法及びそれを含有する抗アレルギー剤 - Google Patents

新規なトリアゾロキナゾリン，その製法及びそれを含有する抗アレルギー剤

Info

Publication number
JPS5892681A
JPS5892681A JP57203827A JP20382782A JPS5892681A JP S5892681 A JPS5892681 A JP S5892681A JP 57203827 A JP57203827 A JP 57203827A JP 20382782 A JP20382782 A JP 20382782A JP S5892681 A JPS5892681 A JP S5892681A
Authority
JP
Japan
Prior art keywords
group
butyl
carbon atoms
methyl
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57203827A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0314314B2 (fr
Inventor
ライナ−・シユレツカ−
ル−ドウイツヒ・フリ−ドリツヒ
デイ−タ−・レンケ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JPS5892681A publication Critical patent/JPS5892681A/ja
Publication of JPH0314314B2 publication Critical patent/JPH0314314B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP57203827A 1981-11-25 1982-11-22 新規なトリアゾロキナゾリン，その製法及びそれを含有する抗アレルギー剤 Granted JPS5892681A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813146599 DE3146599A1 (de) 1981-11-25 1981-11-25 Neue triazolochinazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3146599.4 1981-11-25

Publications (2)

Publication Number Publication Date
JPS5892681A true JPS5892681A (ja) 1983-06-02
JPH0314314B2 JPH0314314B2 (fr) 1991-02-26

Family

ID=6147105

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57203827A Granted JPS5892681A (ja) 1981-11-25 1982-11-22 新規なトリアゾロキナゾリン，その製法及びそれを含有する抗アレルギー剤

Country Status (7)

Country Link
US (1) US4463007A (fr)
EP (1) EP0080176B1 (fr)
JP (1) JPS5892681A (fr)
AT (1) ATE18050T1 (fr)
CA (1) CA1215365A (fr)
DE (2) DE3146599A1 (fr)
ZA (1) ZA828639B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61165386A (ja) * 1984-10-01 1986-07-26 チバ−ガイギ−　アクチエンゲゼルシヤフト トリアゾロキナゾリン化合物、その製法、およびそれを含む医薬組成物
JP2017128603A (ja) * 2017-04-12 2017-07-27 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物
US10092575B2 (en) 2012-06-18 2018-10-09 Dart Neuroscience (Cayman) Ltd. Substituted thiophene- and furan-fused azolopyrimidine-5-(6H)-one compounds

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
EP0217748B1 (fr) * 1985-09-30 1991-02-06 Ciba-Geigy Ag [1,2,4]Triazolo[1,5-c]pyrimidines condensées en e et substituées en 2, compositions pharmaceutiques et leur utilisation
US4831013A (en) * 1986-03-20 1989-05-16 Ciba-Geigy Corporation 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines, pharmaceutical compositions, and uses thereof
DE4241564A1 (de) * 1992-12-10 1994-06-16 Basf Ag Triazolochinazoline zur Behandlung zentralnervöser Erkrankungen
DE4241563A1 (de) * 1992-12-10 1994-06-16 Basf Ag Neue Triazolochinazoline, ihre Herstellung und Verwendung
DE4241562A1 (de) * 1992-12-10 1994-06-16 Basf Ag Neue Triazolopyrimidone, ihre Herstellung und Verwendung
GB201516616D0 (en) * 2015-09-18 2015-11-04 Redx Pharma Plc Antibacterial compounds
GB2575490A (en) * 2018-07-12 2020-01-15 Recordati Ind Chimica E Farmaceutica Spa P2X3 receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053600A (en) * 1973-03-08 1977-10-11 Sandoz, Inc. Tricyclic 1,2,4-triazolo-quinazolines
US3850932A (en) * 1973-06-28 1974-11-26 Sandoz Ag 5-(2-carboxy and 2-carboalkoxy-phenylamino)-1,2,4-triazolo-quinazolines
US4128644A (en) * 1977-07-29 1978-12-05 E. R. Squibb & Sons, Inc. Pyrazolo(1,5-c)quinazoline derivatives and related compounds
US4164578A (en) * 1977-07-29 1979-08-14 E. R. Squibb & Sons, Inc. Pyrazolo[1,5-c]quinazoline derivatives and related compounds

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61165386A (ja) * 1984-10-01 1986-07-26 チバ−ガイギ−　アクチエンゲゼルシヤフト トリアゾロキナゾリン化合物、その製法、およびそれを含む医薬組成物
US10092575B2 (en) 2012-06-18 2018-10-09 Dart Neuroscience (Cayman) Ltd. Substituted thiophene- and furan-fused azolopyrimidine-5-(6H)-one compounds
US10105367B2 (en) 2012-06-18 2018-10-23 Dart Neuroscience (Cayman) Ltd. Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6h)-ones
US10376514B2 (en) 2012-06-18 2019-08-13 Dart Neuroscience (Cayman) Ltd. Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6H)-ones
JP2017128603A (ja) * 2017-04-12 2017-07-27 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物

Also Published As

Publication number Publication date
ATE18050T1 (de) 1986-03-15
JPH0314314B2 (fr) 1991-02-26
DE3146599A1 (de) 1983-07-07
CA1215365A (fr) 1986-12-16
ZA828639B (en) 1983-10-26
EP0080176A1 (fr) 1983-06-01
EP0080176B1 (fr) 1986-02-19
DE3269241D1 (en) 1986-03-27
US4463007A (en) 1984-07-31

Similar Documents

Publication Publication Date Title
AU2018267545B2 (en) Amide-substituted heterocyclic compounds useful as modulators of il-12, il-23 and/or ifn alpha responses
DE69636671T2 (de) Pyrido[2,3-]-pyrimidine und deren Verwendung beim Inhibieren von Zellproliferation und Protein-Tyrosin-Kinase-Enzymaktivität
AU2006311914B2 (en) Heterocyclic compounds as tyrosine kinase modulators
EP2802577B1 (fr) Composés pyridyles à substitution triazolyle utiles comme inhibiteurs de kinases
TWI401256B (zh) 包含苯并咪唑單元之三環ｎ-雜芳基甲醯胺衍生物，其製備及其治療用途
PT90890B (pt) Processo de preparacao de derivados da pirimido-pirimidina, dos seus intermediarios e de composicoes farmaceuticas que os contem
PT93823B (pt) Processo para a preparacao de derivados de pirimidina e de composicoes farmaceuticas que os contem
JPH0288577A (ja) プリノン誘導体およびその製造方法
CZ9302005A3 (en) Azaquinoxalines, process of their preparation and their use
CZ342595A3 (en) Purine derivatives, process of their preparation and pharmaceutical compositions containing thereof
ES2239732T3 (es) Nuevas 4-aminofuropirimidinas y su uso.
JPS5892681A (ja) 新規なトリアゾロキナゾリン，その製法及びそれを含有する抗アレルギー剤
DD272649A5 (de) Neue tricyclische benzimidazole, verfahren zu ihrer herstellung und verwendung als arzneimittel
PL169927B1 (pl) Sposób wytwarzania nowych zwiazków benzochinazolinowych PL PL PL PL
JP2024537394A (ja) 修飾タンパク質およびタンパク質分解剤
PT88614B (pt) Processo para a preparacao de antagonistas do factor activador de plaquetas di-hidropiridinicos
KR900003650B1 (ko) (1h-테트라졸-5-일)-2(1h)-퀴놀리논, 나프티리디논 및 그의 제조방법
KR900003649B1 (ko) (1H-테트라졸-5-일)테트라졸로[1,5-a]-퀴놀린의 제조방법
JPS60184086A (ja) 化合物
JPH0450310B2 (fr)
CA2856100C (fr) Composes cycliques condenses contenant de l'azote pour utilisation en tant qu'antagonistes du crth2
JP2514812B2 (ja) ３−（１Ｈ−テトラゾ−ル−５− イル） チエノ〔２，３−ｄ〕 ピリミジン−４（３Ｈ）−オン類
ES2353214T3 (es) Compuestos de quinazolinona sustituidos.
DE69523640T2 (de) Substituierte 6-r-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetische, cardiovaskulare und hypometabolische mittel, und eine sie enthaltende pharmazeutische zubereitung
JPH0140838B2 (fr)