JPS5879972A - シクロヘキセン誘導体の製造方法 - Google Patents

シクロヘキセン誘導体の製造方法

Info

Publication number
JPS5879972A
JPS5879972A JP57180048A JP18004882A JPS5879972A JP S5879972 A JPS5879972 A JP S5879972A JP 57180048 A JP57180048 A JP 57180048A JP 18004882 A JP18004882 A JP 18004882A JP S5879972 A JPS5879972 A JP S5879972A
Authority
JP
Japan
Prior art keywords
formula
compound
reaction
water
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57180048A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0449530B2 (enExample
Inventor
エ−リツヒ・ビドマ−
ラインハルト・ツエル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5879972A publication Critical patent/JPS5879972A/ja
Publication of JPH0449530B2 publication Critical patent/JPH0449530B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5435—Cycloaliphatic phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57180048A 1981-10-16 1982-10-15 シクロヘキセン誘導体の製造方法 Granted JPS5879972A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH662681 1981-10-16
CH6626/81-7 1981-10-16

Publications (2)

Publication Number Publication Date
JPS5879972A true JPS5879972A (ja) 1983-05-13
JPH0449530B2 JPH0449530B2 (enExample) 1992-08-11

Family

ID=4312534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57180048A Granted JPS5879972A (ja) 1981-10-16 1982-10-15 シクロヘキセン誘導体の製造方法

Country Status (5)

Country Link
US (1) US4579973A (enExample)
EP (1) EP0077439B1 (enExample)
JP (1) JPS5879972A (enExample)
AT (1) ATE22438T1 (enExample)
DE (1) DE3273463D1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517197A (ja) * 2002-07-29 2006-07-20 ハワイ バイオテック， インコーポレイテッド 病気の抑制と改善のための構造上のカロチノイド類似体

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077439B1 (de) * 1981-10-16 1986-09-24 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten, sowie ein neues Ausgangsprodukt und neue Zwischenprodukte in diesem Verfahren
EP0085763B1 (de) * 1982-02-09 1985-06-05 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten
US5827652A (en) 1995-10-31 1998-10-27 Applied Food Biotechnology, Inc. Zeaxanthin formulations for human ingestion
US7691406B2 (en) * 2000-10-27 2010-04-06 ZeaVision LLC. Zeaxanthin formulations for human ingestion
US8088363B2 (en) 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
US9192586B2 (en) 2003-03-10 2015-11-24 Zeavision Llc Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders
US20070082066A1 (en) * 2003-05-07 2007-04-12 Gierhart Dennis L Use of zeaxanthin to reduce light hyper-sensitivity, photophobia, and medical conditions relating to light hyper-sensitivity
US7941211B2 (en) * 2003-11-17 2011-05-10 Zeavision, Llc. Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders
US20060089411A1 (en) * 2004-08-07 2006-04-27 Gierhart Dennis L Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin
CN105578891A (zh) 2013-09-24 2016-05-11 帝斯曼知识产权资产管理有限公司 澄清液体制剂及含澄清液体制剂的澄清饮料
US20180042261A1 (en) 2015-03-26 2018-02-15 Dsm Ip Assets B.V. New color for gums and jellies
EP3072402A1 (en) 2015-03-26 2016-09-28 DSM IP Assets B.V. New red color for edible coatings
EP3072400B1 (en) 2015-03-26 2017-10-04 DSM IP Assets B.V. New color for beverages
EP3273791A1 (en) 2015-03-26 2018-01-31 DSM IP Assets B.V. New color for edible coatings

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839421A (en) * 1969-07-04 1974-10-01 Hoffmann La Roche Polyene compounds
US4000198A (en) * 1975-06-09 1976-12-28 Hoffmann-La Roche Inc. Hydroxy-acetylene-substituted cyclohexenone
CH623304A5 (enExample) * 1975-11-30 1981-05-29 Hoffmann La Roche
US4193850A (en) * 1979-04-12 1980-03-18 Hoffmann-La Roche Inc. Alkanoyloxylation of beta-ionone
ATE3419T1 (de) * 1979-11-28 1983-06-15 F. Hoffmann-La Roche & Co. Aktiengesellschaft Verfahren zur herstellung von cyclohexenderivaten.
EP0077439B1 (de) * 1981-10-16 1986-09-24 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten, sowie ein neues Ausgangsprodukt und neue Zwischenprodukte in diesem Verfahren
EP0085763B1 (de) * 1982-02-09 1985-06-05 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cyclohexenderivaten

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006517197A (ja) * 2002-07-29 2006-07-20 ハワイ バイオテック， インコーポレイテッド 病気の抑制と改善のための構造上のカロチノイド類似体
JP2010248243A (ja) * 2002-07-29 2010-11-04 Cardax Pharmaceuticals Inc 病気の抑制と改善のための構造上のカロチノイド類似体

Also Published As

Publication number Publication date
EP0077439A2 (de) 1983-04-27
DE3273463D1 (en) 1986-10-30
US4579973A (en) 1986-04-01
EP0077439A3 (en) 1984-02-01
ATE22438T1 (de) 1986-10-15
EP0077439B1 (de) 1986-09-24
JPH0449530B2 (enExample) 1992-08-11

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