JPS5846510B2 - １３，１４−デヒドロ−１１−デオキシ−プロスタグランジン及びその製造法 - Google Patents

１３，１４−デヒドロ−１１−デオキシ−プロスタグランジン及びその製造法

Info

Publication number
JPS5846510B2
JPS5846510B2 JP51028026A JP2802676A JPS5846510B2 JP S5846510 B2 JPS5846510 B2 JP S5846510B2 JP 51028026 A JP51028026 A JP 51028026A JP 2802676 A JP2802676 A JP 2802676A JP S5846510 B2 JPS5846510 B2 JP S5846510B2
Authority
JP
Japan
Prior art keywords
hydroxy
methyl
acid
oxo
prost
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51028026A
Other languages
English (en)
Japanese (ja)
Other versions
JPS51115448A (en
Inventor
アンゲロ・フマガリ
カルメロ・カンドルフイ
フランコ・フアウスチニ
レナト・ペレガータ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUAAMITARIA KARURO ERUBA SpA
Original Assignee
FUAAMITARIA KARURO ERUBA SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUAAMITARIA KARURO ERUBA SpA filed Critical FUAAMITARIA KARURO ERUBA SpA
Publication of JPS51115448A publication Critical patent/JPS51115448A/ja
Publication of JPS5846510B2 publication Critical patent/JPS5846510B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP51028026A 1975-03-14 1976-03-15 １３，１４−デヒドロ−１１−デオキシ−プロスタグランジン及びその製造法 Expired JPS5846510B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21264/75A IT1037126B (it) 1975-03-14 1975-03-14 13.4 deidro ii desossi prosta glandine

Publications (2)

Publication Number Publication Date
JPS51115448A JPS51115448A (en) 1976-10-12
JPS5846510B2 true JPS5846510B2 (ja) 1983-10-17

Family

ID=11179220

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51028026A Expired JPS5846510B2 (ja) 1975-03-14 1976-03-15 １３，１４−デヒドロ−１１−デオキシ−プロスタグランジン及びその製造法

Country Status (20)

Country Link
US (1) US4198430A (en, 2012)
JP (1) JPS5846510B2 (en, 2012)
AT (1) AT357699B (en, 2012)
BE (1) BE839533A (en, 2012)
CA (1) CA1103242A (en, 2012)
CH (1) CH618680A5 (en, 2012)
CS (1) CS189001B2 (en, 2012)
CY (1) CY1113A (en, 2012)
DE (1) DE2610503C2 (en, 2012)
DK (1) DK147070C (en, 2012)
FR (1) FR2303533A1 (en, 2012)
GB (2) GB1531567A (en, 2012)
HK (1) HK24881A (en, 2012)
HU (1) HU175728B (en, 2012)
IL (1) IL49189A (en, 2012)
IT (1) IT1037126B (en, 2012)
MY (1) MY8200137A (en, 2012)
NL (1) NL7602646A (en, 2012)
SE (1) SE428922B (en, 2012)
ZA (1) ZA761538B (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU501803B2 (en) * 1975-03-21 1979-06-28 Farmitalia Carlo Erba S.P.A. Fluoro-prostaglandins
ZA77160B (en) * 1976-02-13 1977-11-30 Upjohn Co Prostaglandin analogs
US4328355A (en) * 1976-12-27 1982-05-04 G. D. Searle & Co. Prostaglandin derivatives having aryl, hydroxyl, and alkynyl functions in one side chain
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
EP2875022B1 (en) 2012-07-19 2016-10-12 Cayman Chemical Company, Incorporated Difluorolactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated disease and conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935234A (en) * 1971-08-17 1976-01-27 Universal Oil Products Company Chemical condensation improvement
GB1409637A (en) * 1972-04-14 1975-10-08 Searle & Co Pentaneheptanoic acid derivatives

Also Published As

Publication number Publication date
IT1037126B (it) 1979-11-10
DE2610503A1 (de) 1976-09-30
ATA184076A (de) 1979-12-15
MY8200137A (en) 1982-12-31
ZA761538B (en) 1977-03-30
HK24881A (en) 1981-06-12
CH618680A5 (en, 2012) 1980-08-15
US4198430A (en) 1980-04-15
IL49189A (en) 1980-03-31
JPS51115448A (en) 1976-10-12
FR2303533A1 (fr) 1976-10-08
BE839533A (fr) 1976-07-01
CS189001B2 (en) 1979-03-30
NL7602646A (nl) 1976-09-16
DK147070C (da) 1984-09-10
CY1113A (en) 1981-12-04
CA1103242A (en) 1981-06-16
AU1191376A (en) 1977-09-15
FR2303533B1 (en, 2012) 1979-09-28
GB1531568A (en) 1978-11-08
AT357699B (de) 1980-07-25
IL49189A0 (en) 1976-05-31
DK147070B (da) 1984-04-02
DK110476A (da) 1976-09-15
DE2610503C2 (de) 1986-09-18
SE428922B (sv) 1983-08-01
SE7603223L (sv) 1976-09-15
HU175728B (hu) 1980-10-28
GB1531567A (en) 1978-11-08

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