BE839533A - 13,14-deshydro-11-desoxy-prostaglandines optiquement actives, leur preparation et leur emploi dans des compositions pharmaceutiques - Google Patents

13,14-deshydro-11-desoxy-prostaglandines optiquement actives, leur preparation et leur emploi dans des compositions pharmaceutiques

Info

Publication number
BE839533A
BE839533A BE165138A BE165138A BE839533A BE 839533 A BE839533 A BE 839533A BE 165138 A BE165138 A BE 165138A BE 165138 A BE165138 A BE 165138A BE 839533 A BE839533 A BE 839533A
Authority
BE
Belgium
Prior art keywords
deshydro
desoxy
prostaglandins
preparation
pharmaceutical compositions
Prior art date
Application number
BE165138A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE839533A publication Critical patent/BE839533A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE165138A 1975-03-14 1976-03-12 13,14-deshydro-11-desoxy-prostaglandines optiquement actives, leur preparation et leur emploi dans des compositions pharmaceutiques BE839533A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21264/75A IT1037126B (it) 1975-03-14 1975-03-14 13.4 deidro ii desossi prosta glandine

Publications (1)

Publication Number Publication Date
BE839533A true BE839533A (fr) 1976-07-01

Family

ID=11179220

Family Applications (1)

Application Number Title Priority Date Filing Date
BE165138A BE839533A (fr) 1975-03-14 1976-03-12 13,14-deshydro-11-desoxy-prostaglandines optiquement actives, leur preparation et leur emploi dans des compositions pharmaceutiques

Country Status (20)

Country Link
US (1) US4198430A (en, 2012)
JP (1) JPS5846510B2 (en, 2012)
AT (1) AT357699B (en, 2012)
BE (1) BE839533A (en, 2012)
CA (1) CA1103242A (en, 2012)
CH (1) CH618680A5 (en, 2012)
CS (1) CS189001B2 (en, 2012)
CY (1) CY1113A (en, 2012)
DE (1) DE2610503C2 (en, 2012)
DK (1) DK147070C (en, 2012)
FR (1) FR2303533A1 (en, 2012)
GB (2) GB1531567A (en, 2012)
HK (1) HK24881A (en, 2012)
HU (1) HU175728B (en, 2012)
IL (1) IL49189A (en, 2012)
IT (1) IT1037126B (en, 2012)
MY (1) MY8200137A (en, 2012)
NL (1) NL7602646A (en, 2012)
SE (1) SE428922B (en, 2012)
ZA (1) ZA761538B (en, 2012)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4099015A (en) * 1976-02-13 1978-07-04 The Upjohn Company 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGE2 compounds
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU501803B2 (en) * 1975-03-21 1979-06-28 Farmitalia Carlo Erba S.P.A. Fluoro-prostaglandins
US4328355A (en) * 1976-12-27 1982-05-04 G. D. Searle & Co. Prostaglandin derivatives having aryl, hydroxyl, and alkynyl functions in one side chain
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
EP2875022B1 (en) 2012-07-19 2016-10-12 Cayman Chemical Company, Incorporated Difluorolactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated disease and conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935234A (en) * 1971-08-17 1976-01-27 Universal Oil Products Company Chemical condensation improvement
GB1409637A (en) * 1972-04-14 1975-10-08 Searle & Co Pentaneheptanoic acid derivatives

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4099015A (en) * 1976-02-13 1978-07-04 The Upjohn Company 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGE2 compounds
US4104474A (en) * 1976-02-13 1978-08-01 The Upjohn Company 5-Oxa-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF1α co
US4113964A (en) * 1976-02-13 1978-09-12 The Upjohn Company 13,14-Didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF1 α compounds
US4113966A (en) * 1976-02-13 1978-09-12 The Upjohn Company 3,7-Inter-m-phenylene-3-oxa-4,5,6-trinor-13,14-didehydro-11-deoxy-PGF1 α compounds
US4113963A (en) * 1976-02-13 1978-09-12 The Upjohn Company 13,14-Didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGE1 compounds
US4113962A (en) * 1976-02-13 1978-09-12 The Upjohn Company 5-Oxa-13,14-didehydro-11-deoxy-17-phenyl-18,19,20 trinor-PGE1 compounds
US4113961A (en) * 1976-02-13 1978-09-12 The Upjohn Company 3,7-Inter-m-phenylene-3-oxa-4,5,6-trinor-13,14-didehydro-11-deoxy-PGE1
US4113965A (en) * 1976-02-13 1978-09-12 The Upjohn Company 3,7-Inter-m-phenylene-3-oxa-13,14-didehydro-11-deoxy-17-phenyl-4,5,6,18,19,20-hexanor-PGF1 α compounds
US4115651A (en) * 1976-02-13 1978-09-19 The Upjohn Company CIS-4,5-Didehydro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub.1α compounds
US4117233A (en) * 1976-02-13 1978-09-26 The Upjohn Company 2,2-Difluoro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF2 α compounds
US4121038A (en) * 1976-02-13 1978-10-17 The Upjohn Company 3,7-Inter-m-phenylene-3-oxa-13,14-didehydro-11-deoxy-17-phenyl-4,5,6,18,19,20-hexanor-PGE1 compounds
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain

Also Published As

Publication number Publication date
IT1037126B (it) 1979-11-10
DE2610503A1 (de) 1976-09-30
ATA184076A (de) 1979-12-15
MY8200137A (en) 1982-12-31
ZA761538B (en) 1977-03-30
HK24881A (en) 1981-06-12
CH618680A5 (en, 2012) 1980-08-15
US4198430A (en) 1980-04-15
IL49189A (en) 1980-03-31
JPS51115448A (en) 1976-10-12
FR2303533A1 (fr) 1976-10-08
JPS5846510B2 (ja) 1983-10-17
CS189001B2 (en) 1979-03-30
NL7602646A (nl) 1976-09-16
DK147070C (da) 1984-09-10
CY1113A (en) 1981-12-04
CA1103242A (en) 1981-06-16
AU1191376A (en) 1977-09-15
FR2303533B1 (en, 2012) 1979-09-28
GB1531568A (en) 1978-11-08
AT357699B (de) 1980-07-25
IL49189A0 (en) 1976-05-31
DK147070B (da) 1984-04-02
DK110476A (da) 1976-09-15
DE2610503C2 (de) 1986-09-18
SE428922B (sv) 1983-08-01
SE7603223L (sv) 1976-09-15
HU175728B (hu) 1980-10-28
GB1531567A (en) 1978-11-08

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Legal Events

Date Code Title Description
CN Change of patent owner's name

Owner name: *FARMITALIA CARLO ERBA S.R.L.

Effective date: 19880627

RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.R.L.

Effective date: 19910331