JPS583679B2 - タイエキチユウノ カサンカセイサヨウブツシツオ ケンシユツスルタメノ シケンヘン - Google Patents
タイエキチユウノ カサンカセイサヨウブツシツオ ケンシユツスルタメノ シケンヘンInfo
- Publication number
- JPS583679B2 JPS583679B2 JP48082404A JP8240473A JPS583679B2 JP S583679 B2 JPS583679 B2 JP S583679B2 JP 48082404 A JP48082404 A JP 48082404A JP 8240473 A JP8240473 A JP 8240473A JP S583679 B2 JPS583679 B2 JP S583679B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- hydroperoxide
- test
- solution
- taiekichiyuuno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000012360 testing method Methods 0.000 claims description 35
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 14
- 150000001875 compounds Chemical class 0.000 claims description 13
- 102000003992 Peroxidases Human genes 0.000 claims description 12
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 12
- 239000003381 stabilizer Substances 0.000 claims description 9
- 210000001124 body fluid Anatomy 0.000 claims description 7
- 239000010839 body fluid Substances 0.000 claims description 7
- 239000013543 active substance Substances 0.000 claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims description 4
- 125000003545 alkoxy group Chemical group 0.000 claims description 3
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 19
- 239000000123 paper Substances 0.000 description 11
- 239000000203 mixture Substances 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 238000001514 detection method Methods 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 238000006243 chemical reaction Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 150000002432 hydroperoxides Chemical class 0.000 description 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- 239000012190 activator Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000003743 erythrocyte Anatomy 0.000 description 6
- RNVCVTLRINQCPJ-UHFFFAOYSA-N o-toluidine Chemical compound CC1=CC=CC=C1N RNVCVTLRINQCPJ-UHFFFAOYSA-N 0.000 description 6
- 150000001408 amides Chemical class 0.000 description 5
- 239000000872 buffer Substances 0.000 description 5
- 238000001035 drying Methods 0.000 description 5
- 230000035945 sensitivity Effects 0.000 description 5
- 238000003860 storage Methods 0.000 description 5
- WXMQHPKQCPCDQO-UHFFFAOYSA-N 4-dimorpholin-4-ylphosphorylmorpholine Chemical compound C1COCCN1P(N1CCOCC1)(=O)N1CCOCC1 WXMQHPKQCPCDQO-UHFFFAOYSA-N 0.000 description 4
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- -1 dialdehyde polysaccharides Chemical class 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 230000008018 melting Effects 0.000 description 4
- 238000002844 melting Methods 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 230000000087 stabilizing effect Effects 0.000 description 4
- 239000000080 wetting agent Substances 0.000 description 4
- CDOUZKKFHVEKRI-UHFFFAOYSA-N 3-bromo-n-[(prop-2-enoylamino)methyl]propanamide Chemical compound BrCCC(=O)NCNC(=O)C=C CDOUZKKFHVEKRI-UHFFFAOYSA-N 0.000 description 3
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical group ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 238000004820 blood count Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000007979 citrate buffer Substances 0.000 description 3
- 235000019329 dioctyl sodium sulphosuccinate Nutrition 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000005470 impregnation Methods 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000007800 oxidant agent Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- OKIRBHVFJGXOIS-UHFFFAOYSA-N 1,2-di(propan-2-yl)benzene Chemical compound CC(C)C1=CC=CC=C1C(C)C OKIRBHVFJGXOIS-UHFFFAOYSA-N 0.000 description 2
- MOMKYJPSVWEWPM-UHFFFAOYSA-N 4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole Chemical compound C1=CC(C)=CC=C1C1=NC(CCl)=CS1 MOMKYJPSVWEWPM-UHFFFAOYSA-N 0.000 description 2
- XRMYRYBUDMXTFQ-UHFFFAOYSA-N 4-[morpholin-4-yl(phenyl)phosphoryl]morpholine Chemical compound C1COCCN1P(C=1C=CC=CC=1)(=O)N1CCOCC1 XRMYRYBUDMXTFQ-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
- FZERHIULMFGESH-UHFFFAOYSA-N N-phenylacetamide Chemical compound CC(=O)NC1=CC=CC=C1 FZERHIULMFGESH-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 238000001792 White test Methods 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- HFACYLZERDEVSX-UHFFFAOYSA-N benzidine Chemical compound C1=CC(N)=CC=C1C1=CC=C(N)C=C1 HFACYLZERDEVSX-UHFFFAOYSA-N 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- RWGFKTVRMDUZSP-UHFFFAOYSA-N cumene Chemical compound CC(C)C1=CC=CC=C1 RWGFKTVRMDUZSP-UHFFFAOYSA-N 0.000 description 2
- YQHLDYVWEZKEOX-UHFFFAOYSA-N cumene hydroperoxide Chemical compound OOC(C)(C)C1=CC=CC=C1 YQHLDYVWEZKEOX-UHFFFAOYSA-N 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 229960001484 edetic acid Drugs 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- GNOIPBMMFNIUFM-UHFFFAOYSA-N hexamethylphosphoric triamide Chemical compound CN(C)P(=O)(N(C)C)N(C)C GNOIPBMMFNIUFM-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- CFJYNSNXFXLKNS-UHFFFAOYSA-N p-menthane Chemical compound CC(C)C1CCC(C)CC1 CFJYNSNXFXLKNS-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 235000019983 sodium metaphosphate Nutrition 0.000 description 2
- CIHOLLKRGTVIJN-UHFFFAOYSA-N tert‐butyl hydroperoxide Chemical compound CC(C)(C)OO CIHOLLKRGTVIJN-UHFFFAOYSA-N 0.000 description 2
- SBUBPFHJZHQNNT-UHFFFAOYSA-N 1,2-di(propan-2-yl)benzene hydrogen peroxide Chemical compound OO.OO.CC(C)C1=CC=CC=C1C(C)C SBUBPFHJZHQNNT-UHFFFAOYSA-N 0.000 description 1
- XSZYESUNPWGWFQ-UHFFFAOYSA-N 1-(2-hydroperoxypropan-2-yl)-4-methylcyclohexane Chemical compound CC1CCC(C(C)(C)OO)CC1 XSZYESUNPWGWFQ-UHFFFAOYSA-N 0.000 description 1
- YWBMNCRJFZGXJY-UHFFFAOYSA-N 1-hydroperoxy-1,2,3,4-tetrahydronaphthalene Chemical compound C1=CC=C2C(OO)CCCC2=C1 YWBMNCRJFZGXJY-UHFFFAOYSA-N 0.000 description 1
- LIZVXGBYTGTTTI-UHFFFAOYSA-N 2-[(4-methylphenyl)sulfonylamino]-2-phenylacetic acid Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(C(O)=O)C1=CC=CC=C1 LIZVXGBYTGTTTI-UHFFFAOYSA-N 0.000 description 1
- WBIQQQGBSDOWNP-UHFFFAOYSA-N 2-dodecylbenzenesulfonic acid Chemical compound CCCCCCCCCCCCC1=CC=CC=C1S(O)(=O)=O WBIQQQGBSDOWNP-UHFFFAOYSA-N 0.000 description 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- 235000001258 Cinchona calisaya Nutrition 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 102000002397 Kinins Human genes 0.000 description 1
- 108010093008 Kinins Proteins 0.000 description 1
- WZKXBGJNNCGHIC-UHFFFAOYSA-N Leucomalachite green Chemical compound C1=CC(N(C)C)=CC=C1C(C=1C=CC(=CC=1)N(C)C)C1=CC=CC=C1 WZKXBGJNNCGHIC-UHFFFAOYSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 102000036675 Myoglobin Human genes 0.000 description 1
- 108010062374 Myoglobin Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 229910019213 POCl3 Inorganic materials 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- 241000978776 Senegalia senegal Species 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000006568 Urinary Bladder Calculi Diseases 0.000 description 1
- 208000012931 Urologic disease Diseases 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 229960001413 acetanilide Drugs 0.000 description 1
- 235000019270 ammonium chloride Nutrition 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- DGJMPUGMZIKDRO-UHFFFAOYSA-N cyanoacetamide Chemical compound NC(=O)CC#N DGJMPUGMZIKDRO-UHFFFAOYSA-N 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- IBDMRHDXAQZJAP-UHFFFAOYSA-N dichlorophosphorylbenzene Chemical compound ClP(Cl)(=O)C1=CC=CC=C1 IBDMRHDXAQZJAP-UHFFFAOYSA-N 0.000 description 1
- SDIXRDNYIMOKSG-UHFFFAOYSA-L disodium methyl arsenate Chemical compound [Na+].[Na+].C[As]([O-])([O-])=O SDIXRDNYIMOKSG-UHFFFAOYSA-L 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 229940060296 dodecylbenzenesulfonic acid Drugs 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000004374 forensic analysis Methods 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 125000001867 hydroperoxy group Chemical group [*]OO[H] 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- GCQWVBWWADBEDX-UHFFFAOYSA-N n-[dimethylamino(phenyl)phosphoryl]-n-methylmethanamine Chemical compound CN(C)P(=O)(N(C)C)C1=CC=CC=C1 GCQWVBWWADBEDX-UHFFFAOYSA-N 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000004028 organic sulfates Chemical class 0.000 description 1
- 229930004008 p-menthane Natural products 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- CMPQUABWPXYYSH-UHFFFAOYSA-N phenyl phosphate Chemical group OP(O)(=O)OC1=CC=CC=C1 CMPQUABWPXYYSH-UHFFFAOYSA-N 0.000 description 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical compound ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920001290 polyvinyl ester Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229960000948 quinine Drugs 0.000 description 1
- 150000005839 radical cations Chemical class 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 238000011896 sensitive detection Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000008362 succinate buffer Substances 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
- 239000012209 synthetic fiber Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 238000005292 vacuum distillation Methods 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/904—Oxidation - reduction indicators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2235127A DE2235127C2 (de) | 1972-07-18 | 1972-07-18 | Diagnostisches Mittel zum Nachweis von Blut und anderen peroxidatisch wirksamen Substanzen in Körperflüssigkeiten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS4954093A JPS4954093A (en:Method) | 1974-05-25 |
| JPS583679B2 true JPS583679B2 (ja) | 1983-01-22 |
Family
ID=5850903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP48082404A Expired JPS583679B2 (ja) | 1972-07-18 | 1973-07-18 | タイエキチユウノ カサンカセイサヨウブツシツオ ケンシユツスルタメノ シケンヘン |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3853471A (en:Method) |
| JP (1) | JPS583679B2 (en:Method) |
| DE (1) | DE2235127C2 (en:Method) |
| FR (1) | FR2198644A5 (en:Method) |
| GB (1) | GB1390899A (en:Method) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6139779A (ja) * | 1984-07-31 | 1986-02-25 | Sony Corp | 同期信号発生装置 |
| JPS61290872A (ja) * | 1985-06-19 | 1986-12-20 | Canon Inc | 映像信号再生装置 |
| JPS6271975U (en:Method) * | 1985-10-23 | 1987-05-08 |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR204182A1 (es) * | 1973-12-20 | 1975-11-28 | Boehringer Mannheim Gmbh | Tira de ensayo para la comprobacion de substancias de actividad peroxidica en los liquidos del cuerpo |
| US3966414A (en) * | 1974-01-16 | 1976-06-29 | Bio-Medical Sciences, Inc. | Time temperature indicators |
| DE2436598C2 (de) * | 1974-07-30 | 1983-04-07 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabiler Teststreifen zum Nachweis von Inhaltsstoffen in Flüssigkeiten |
| CS175782B1 (en:Method) * | 1974-10-16 | 1977-05-31 | ||
| DE2460903C3 (de) | 1974-12-21 | 1981-12-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue 3,3',5,5'-Tetraalkylbenzidine |
| DE2462952C2 (en:Method) * | 1974-12-21 | 1987-10-01 | Boehringer Mannheim Gmbh, 6800 Mannheim, De | |
| CS176664B1 (en:Method) * | 1975-02-14 | 1977-06-30 | ||
| JPS5263794A (en) * | 1975-11-21 | 1977-05-26 | Shionogi Seiyaku Kk | Test piece for latent blood |
| US4071321A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances |
| CA1098808A (en) * | 1977-03-14 | 1981-04-07 | Charles T. W. Lam | Test composition and device for determining peroxidatively active substances |
| US4071318A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances |
| US4071317A (en) * | 1977-03-14 | 1978-01-31 | Miles Laboratories, Inc. | Test composition and device for determining peroxidatively active substances and process for preparing same |
| DE2728236B2 (de) * | 1977-06-23 | 1980-09-18 | Wolfgang Dr. 3300 Braunschweig Hirsch | Stabilisierte diagnostische Zubereitung zum Nachweis von Urobilinogen |
| US4175923A (en) * | 1978-06-26 | 1979-11-27 | Friend William G | Method and apparatus for occult blood testing in the home |
| US4279993A (en) * | 1979-11-13 | 1981-07-21 | Magers Thomas A | Indicator composition and test device containing amine oxide, and method of use |
| DE3025372A1 (de) * | 1980-07-04 | 1982-01-28 | Behringwerke Ag, 3550 Marburg | Mittel zum nachweis peroxidatisch wirksamer substanzen und verwendung von polyvinylmethylacylamid in einem solchen |
| US4382064A (en) * | 1981-01-29 | 1983-05-03 | Smithkline Instruments, Inc. | Specimen slide for occult blood testing |
| US4329317A (en) * | 1981-01-29 | 1982-05-11 | Smithkline Instruments, Inc. | Method of stabilizing a specimen slide for occult blood testing |
| US4956300A (en) * | 1982-01-05 | 1990-09-11 | Helena Laboratories Corporation | Aid for determining the presence of occult blood, method of making the aid, and method of using the aid |
| US4556640A (en) * | 1983-06-29 | 1985-12-03 | Miles Laboratories, Inc. | Stabilized test composition, device and method for the determination of peroxidatively active substances |
| US4615972A (en) * | 1983-11-04 | 1986-10-07 | Immuno Concepts, Inc. | Stabilization of indicators for detecting enzyme activity |
| US5702913A (en) * | 1983-12-21 | 1997-12-30 | Helena Laboratories Corporation | Chromgen-reagent test system |
| US5273888A (en) * | 1984-01-16 | 1993-12-28 | Helena Laboratories Corporation | Chemical test kit and method for determining the presence of blood in a specimen and for verifying the effectiveness of the chemicals |
| US4755472A (en) * | 1986-01-16 | 1988-07-05 | Miles Inc. | Stable composition for the determination of peroxidatively active substances |
| US5369013A (en) * | 1987-06-22 | 1994-11-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method, reagent mixture and kit for determining the presence of bacterial or somatic cells in urine |
| US5081040A (en) * | 1987-06-29 | 1992-01-14 | Helena Laboratories Corporation | Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes |
| US5217874A (en) * | 1989-04-04 | 1993-06-08 | Helena Laboratories Corporation | Fecal occult blood test product with positive and negative controls |
| US5196167A (en) * | 1989-04-04 | 1993-03-23 | Helena Laboratories Corporation | Fecal occult blood test product with positive and negative controls |
| US5089420A (en) * | 1990-01-30 | 1992-02-18 | Miles Inc. | Composition, device and method of assaying for a peroxidatively active substance utilizing amine borate compounds |
| US5318894A (en) * | 1990-01-30 | 1994-06-07 | Miles Inc. | Composition, device and method of assaying for peroxidatively active substances |
| GB2291658B (en) | 1994-07-23 | 1998-08-12 | Ciba Geigy Ag | Aqueous textile treatment compositions containing an ultra-violet absorbing agent |
| US5827677A (en) * | 1996-02-01 | 1998-10-27 | Universal Lavel | Method and device for specifically detecting myoglobin using a non-discriminating peroxidase sensitive assay |
| AU690506B3 (en) * | 1997-07-23 | 1998-04-23 | Paul John Lemmerman | Tongue wash |
| US20050104031A1 (en) * | 2003-01-21 | 2005-05-19 | Lyle Steimel | Phosphonamide and phosphonamide blend compositions and method to treat water |
| US8012761B2 (en) | 2006-12-14 | 2011-09-06 | Kimberly-Clark Worldwide, Inc. | Detection of formaldehyde in urine samples |
| US7846383B2 (en) | 2006-12-15 | 2010-12-07 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay device and absorbent article containing same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL277911A (en:Method) * | 1961-05-04 | |||
| NL126365C (en:Method) * | 1963-06-24 |
-
1972
- 1972-07-18 DE DE2235127A patent/DE2235127C2/de not_active Expired
-
1973
- 1973-07-03 US US00376249A patent/US3853471A/en not_active Expired - Lifetime
- 1973-07-16 GB GB3373073A patent/GB1390899A/en not_active Expired
- 1973-07-18 JP JP48082404A patent/JPS583679B2/ja not_active Expired
- 1973-07-18 FR FR7326254A patent/FR2198644A5/fr not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6139779A (ja) * | 1984-07-31 | 1986-02-25 | Sony Corp | 同期信号発生装置 |
| JPS61290872A (ja) * | 1985-06-19 | 1986-12-20 | Canon Inc | 映像信号再生装置 |
| JPS6271975U (en:Method) * | 1985-10-23 | 1987-05-08 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1390899A (en) | 1975-04-16 |
| FR2198644A5 (en:Method) | 1974-03-29 |
| US3853471A (en) | 1974-12-10 |
| DE2235127C2 (de) | 1974-08-08 |
| DE2235127A1 (en:Method) | 1974-01-10 |
| DE2235127B1 (de) | 1974-01-10 |
| JPS4954093A (en:Method) | 1974-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS583679B2 (ja) | タイエキチユウノ カサンカセイサヨウブツシツオ ケンシユツスルタメノ シケンヘン | |
| US4071317A (en) | Test composition and device for determining peroxidatively active substances and process for preparing same | |
| US4071321A (en) | Test composition and device for determining peroxidatively active substances | |
| US3975161A (en) | Biological diagnostic test strip | |
| US6218571B1 (en) | 8-(anilino)-1-naphthalenesulfonate analogs | |
| JP2922003B2 (ja) | 過酸化活性物質の検定のための組成物、用具及び方法の改良 | |
| JPS583680B2 (ja) | タイエキチユウノ カサンカセイサヨウブツシツオ ケンシユツスルタメノ シケンヘン | |
| JPH0347708B2 (en:Method) | ||
| JPH04213064A (ja) | 過酸化活性物質の検定のための組成物、用具及び方法 | |
| DK159171B (da) | Materiale til detektering af naervaerelsen af et peroxidativt aktivt stof i en testproeve, testmiddel indeholdende materialet samt fremgangsmaade til fremstilling af testmidlet. | |
| JPS5831873B2 (ja) | 過酸化的活性物質と検出するための試験用組成物 | |
| JPS60256056A (ja) | 過酸化水素定量用組成物および分析要素 | |
| EP0167973B1 (de) | Redox-Indikatoren | |
| US3880588A (en) | Diagnostic agent for detecting bilirubin | |
| JPS61138163A (ja) | 発色性カップラー及び過酸化水素又は他の被分析物の測定へのその使用 | |
| CS220789B2 (en) | Diagnostic means for evidence of the leucosyte in the body liquids | |
| US4386053A (en) | Test piece for detection of occult blood | |
| CA1041408A (en) | Diagnostic agent for sacaharides | |
| CA1098808A (en) | Test composition and device for determining peroxidatively active substances | |
| JPS6152300A (ja) | 過酸化水素測定用組成物 | |
| US4481295A (en) | Substituted or condensed pyridines in a process for the detection of substances having a peroxidatic effect and a diagnostic agent containing such pyridines | |
| US4670402A (en) | Use of benzimidazole derivatives for the detection of blood and other peroxidatically active substances in body fluids and excretion products | |
| US4894472A (en) | Dicyanoethylaryl derivatives and process for their preparation | |
| JPH07116382B2 (ja) | 水溶性メチレンビスジアルキルアニリン誘導体及びその塩類並びにそれらを用いた過酸化物質定量用組成物 | |
| JPS59195157A (ja) | 過酸化物活性化物質測定用試験組成物、試験具並びにそれらの使用方法および製造方法 |