JPS5811874B2 - ピリド （３，４−ｄ） ピリダジンルイノ セイゾウホウ - Google Patents

ピリド （３，４−ｄ） ピリダジンルイノ セイゾウホウ

Info

Publication number
JPS5811874B2
JPS5811874B2 JP49033679A JP3367974A JPS5811874B2 JP S5811874 B2 JPS5811874 B2 JP S5811874B2 JP 49033679 A JP49033679 A JP 49033679A JP 3367974 A JP3367974 A JP 3367974A JP S5811874 B2 JPS5811874 B2 JP S5811874B2
Authority
JP
Japan
Prior art keywords
pyridazine
compound
reaction
lower alkyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP49033679A
Other languages
English (en)
Japanese (ja)
Other versions
JPS50129594A (en, 2012
Inventor
菊地慎太郎
万木庄次郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP49033679A priority Critical patent/JPS5811874B2/ja
Priority to NO750939A priority patent/NO141852C/no
Priority to NL7503289A priority patent/NL7503289A/xx
Priority to AT214775A priority patent/AT342064B/de
Priority to CH369075A priority patent/CH597229A5/xx
Priority to DE19752512673 priority patent/DE2512673A1/de
Priority to DK123975AA priority patent/DK134554B/da
Priority to ES0435955A priority patent/ES435955A1/es
Priority to FR7509113A priority patent/FR2265384B1/fr
Priority to HUTA1349A priority patent/HU169631B/hu
Priority to BE154691A priority patent/BE827103A/xx
Priority to AU79448/75A priority patent/AU487706B2/en
Priority to CA222,886A priority patent/CA1044234A/en
Priority to SE7503391A priority patent/SE419987B/xx
Priority to GB12366/75A priority patent/GB1503032A/en
Priority to US05/562,034 priority patent/US4005201A/en
Publication of JPS50129594A publication Critical patent/JPS50129594A/ja
Publication of JPS5811874B2 publication Critical patent/JPS5811874B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP49033679A 1974-03-25 1974-03-25 ピリド （３，４−ｄ） ピリダジンルイノ セイゾウホウ Expired JPS5811874B2 (ja)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP49033679A JPS5811874B2 (ja) 1974-03-25 1974-03-25 ピリド （３，４−ｄ） ピリダジンルイノ セイゾウホウ
NO750939A NO141852C (no) 1974-03-25 1975-03-19 Analogifremgangsmaate til fremstilling av diuretisk aktive pyrido(3,4-d)pyridazinderivater
NL7503289A NL7503289A (nl) 1974-03-25 1975-03-19 Werkwijze ter bereiding van nieuwe 7-(hydroxy- fenyl)pyrido(3,4-d)pyridazinen.
AT214775A AT342064B (de) 1974-03-25 1975-03-20 Verfahren zur herstellung von neuen 7- (4-hydroxyphenyl)pyrido (3,4-d)pyridazinen und ihren salzen
CH369075A CH597229A5 (en, 2012) 1974-03-25 1975-03-21
DE19752512673 DE2512673A1 (de) 1974-03-25 1975-03-21 7-(hydroxyphenyl)pyrido eckige klammer auf 3,4-d eckige klammer zu pyridazine und verfahren zu ihrer herstellung
DK123975AA DK134554B (da) 1974-03-25 1975-03-24 Analogifremgangsmåde til fremstilling af 7-(hydroxyfenyl)-pyrido/3,4-d/-pyridaziner eller salte deraf.
ES0435955A ES435955A1 (es) 1974-03-25 1975-03-24 Un procedimiento para obtener un derivado de pirido (3,4-d) piridezina.
FR7509113A FR2265384B1 (en, 2012) 1974-03-25 1975-03-24
HUTA1349A HU169631B (en, 2012) 1974-03-25 1975-03-24
BE154691A BE827103A (fr) 1974-03-25 1975-03-24 7-(hydroxyphenyl) pyrido (3,4-d) pyridazines
AU79448/75A AU487706B2 (en) 1974-03-25 1975-03-24 7-[hydroxyphenyl] pyrido[3,4-d]pyridazines
CA222,886A CA1044234A (en) 1974-03-25 1975-03-24 7-(hydroxyphenyl)pyrido(3,4-d)pyridazines
SE7503391A SE419987B (sv) 1974-03-25 1975-03-24 Analogiforfarande for framstellning av 7-(hydroxifenyl)pyrido(3,4-d)-pyridaziner
GB12366/75A GB1503032A (en) 1974-03-25 1975-03-25 7-(hydroxyphenyl)pyrido-(3,4-d)pyridazines
US05/562,034 US4005201A (en) 1974-03-25 1975-03-25 7-(Hydroxyphenyl)pyrido(3,4-d)pyridazines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49033679A JPS5811874B2 (ja) 1974-03-25 1974-03-25 ピリド （３，４−ｄ） ピリダジンルイノ セイゾウホウ

Publications (2)

Publication Number Publication Date
JPS50129594A JPS50129594A (en, 2012) 1975-10-13
JPS5811874B2 true JPS5811874B2 (ja) 1983-03-04

Family

ID=12393114

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49033679A Expired JPS5811874B2 (ja) 1974-03-25 1974-03-25 ピリド （３，４−ｄ） ピリダジンルイノ セイゾウホウ

Country Status (15)

Country Link
US (1) US4005201A (en, 2012)
JP (1) JPS5811874B2 (en, 2012)
AT (1) AT342064B (en, 2012)
BE (1) BE827103A (en, 2012)
CA (1) CA1044234A (en, 2012)
CH (1) CH597229A5 (en, 2012)
DE (1) DE2512673A1 (en, 2012)
DK (1) DK134554B (en, 2012)
ES (1) ES435955A1 (en, 2012)
FR (1) FR2265384B1 (en, 2012)
GB (1) GB1503032A (en, 2012)
HU (1) HU169631B (en, 2012)
NL (1) NL7503289A (en, 2012)
NO (1) NO141852C (en, 2012)
SE (1) SE419987B (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2056142A1 (en) * 1990-11-27 1992-05-28 Hirotomo Masuya Pyridopyridazine compounds and their use
DE19500760A1 (de) * 1995-01-13 1996-07-18 Basf Ag Substituierte 2-Phenylpyridine
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
IL159320A0 (en) 2001-06-12 2004-06-01 Wellstat Therapeutics Corp Compounds for the treatment of metabolic disorders
EP1951702A2 (en) * 2005-10-17 2008-08-06 NeuroTherapeutics Pharma, Inc. Diuretic-like compound analogs useful for regulation of central nervous system disorders
CN108484494B (zh) * 2018-06-15 2021-07-30 沈阳药科大学 2-氧代-1,2-二氢吡啶-4-甲酸类化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793345A (fr) * 1971-12-28 1973-06-27 Takeda Chemical Industries Ltd Derives de pyridopyridazine

Also Published As

Publication number Publication date
BE827103A (fr) 1975-09-24
FR2265384B1 (en, 2012) 1980-01-18
JPS50129594A (en, 2012) 1975-10-13
NL7503289A (nl) 1975-09-29
SE7503391L (en, 2012) 1975-09-26
HU169631B (en, 2012) 1976-12-28
NO141852C (no) 1980-06-04
NO141852B (no) 1980-02-11
NO750939L (en, 2012) 1975-09-26
US4005201A (en) 1977-01-25
DK134554B (da) 1976-11-29
SE419987B (sv) 1981-09-07
CH597229A5 (en, 2012) 1978-03-31
AT342064B (de) 1978-03-10
DK123975A (en, 2012) 1975-09-26
ATA214775A (de) 1977-07-15
FR2265384A1 (en, 2012) 1975-10-24
AU7944875A (en) 1976-09-30
ES435955A1 (es) 1977-01-01
DE2512673A1 (de) 1975-10-02
DK134554C (en, 2012) 1977-05-02
CA1044234A (en) 1978-12-12
GB1503032A (en) 1978-03-08

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