JPS58113139A - ラセミ5−フエニル−2−ペンタノ−ルを光学分割する方法 - Google Patents

ラセミ5−フエニル−2−ペンタノ−ルを光学分割する方法

Info

Publication number
JPS58113139A
JPS58113139A JP57185899A JP18589982A JPS58113139A JP S58113139 A JPS58113139 A JP S58113139A JP 57185899 A JP57185899 A JP 57185899A JP 18589982 A JP18589982 A JP 18589982A JP S58113139 A JPS58113139 A JP S58113139A
Authority
JP
Japan
Prior art keywords
phenyl
pentanol
liters
brucine
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57185899A
Other languages
English (en)
Japanese (ja)
Other versions
JPS629575B2 (https=
Inventor
バ−ナ−ド・シ−ルズ・ム−ア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS58113139A publication Critical patent/JPS58113139A/ja
Publication of JPS629575B2 publication Critical patent/JPS629575B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/20Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • C07D221/12Phenanthridines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57185899A 1981-10-22 1982-10-22 ラセミ5−フエニル−2−ペンタノ−ルを光学分割する方法 Granted JPS58113139A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/313,560 US4386205A (en) 1981-10-22 1981-10-22 Resolution of racemic 5-phenyl-2-pentanol
US313560 1981-10-22

Publications (2)

Publication Number Publication Date
JPS58113139A true JPS58113139A (ja) 1983-07-05
JPS629575B2 JPS629575B2 (https=) 1987-02-28

Family

ID=23216222

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57185899A Granted JPS58113139A (ja) 1981-10-22 1982-10-22 ラセミ5−フエニル−2−ペンタノ−ルを光学分割する方法

Country Status (7)

Country Link
US (1) US4386205A (https=)
EP (1) EP0078145B1 (https=)
JP (1) JPS58113139A (https=)
DE (1) DE3272348D1 (https=)
DK (1) DK467182A (https=)
GR (1) GR76762B (https=)
IE (1) IE54053B1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524223A (en) * 1984-01-19 1985-06-18 Uop Inc. Resolution of alcohols using amino acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260764A (en) * 1976-12-22 1981-04-07 Pfizer Inc. 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor
DE2832604A1 (de) * 1978-07-21 1980-01-31 Schering Ag Verfahren zur herstellung von 7 alpha -methyl-oestrogenen

Also Published As

Publication number Publication date
EP0078145B1 (en) 1986-07-30
IE822539L (en) 1983-04-22
JPS629575B2 (https=) 1987-02-28
DE3272348D1 (en) 1986-09-04
EP0078145A1 (en) 1983-05-04
DK467182A (da) 1983-04-23
IE54053B1 (en) 1989-05-24
US4386205A (en) 1983-05-31
GR76762B (https=) 1984-08-31

Similar Documents

Publication Publication Date Title
KR100712003B1 (ko) 펜세린 및 그 유사체의 제조방법
US4284797A (en) Process for separating mixtures of 3- and 4-nitrophthalic acid
CA1207338A (en) Process for the preparation of (d) 2-(6-methoxy-2- naphthyl)propionic acid and pharmaceutically acceptable salts thereof and new intermediates therefor
JPS58113139A (ja) ラセミ5−フエニル−2−ペンタノ−ルを光学分割する方法
JP2002530282A (ja) 改良された7−アザインドリル−3−カルボン酸の製造方法
US4395571A (en) Process for the preparation of d,1-2-(6-methoxy-2-naphthyl)propionic acid
US4150038A (en) Conversion of hesperidin into hesperetin
JPH0375541B2 (https=)
JP2992334B2 (ja) 軟体動物駆除剤の2,4,5―トリブロモピロール―3―カーボニトリル化合物の製造法
JP3907787B2 (ja) 安息香酸誘導体の製造方法
KR920011021B1 (ko) 3r-(3-카복시벤질)-6-(5-플루오로-2-벤조티아졸릴)메톡시-4r-크로마놀에 대한 광학적 분할방법
KR860001545B1 (ko) 키랄 3-(치환된 페닐)-4-(3-하이드록시프로필) 시클로헥산올의 합성방법
JPH05194313A (ja) 2,6−ジヒドロキシ安息香酸の製造方法
CN119874519B (zh) 一种4-(3-酯基氧代丙基)苯甲酸甲酯的合成及原料回收方法
US4698432A (en) Process for the resolution of (±) 2-[2'-(p-fluorophenyl)-5'-benzoxazolyl]-propionic acid
JPS6031824B2 (ja) ヒドロキシフェニルピペリジニルメタノ−ル誘導体の製法
CA1159836A (en) Intermediates for 6,7-dihydro-9-fluoro-5-methyl-1-oxo- 1h,5h-benzo¬ij|quinolizine-2-carboxylic acid
CN121872968A (zh) 一种1-Boc-3-氨基吡咯烷-3-甲酸的合成方法
CA2307989C (en) An improved process for purifying alpha-keto acids
JP2000198779A (ja) 3―アルキルフラバノノ―ル誘導体の精製法
CN120904121A (zh) 2-(4-甲氧基苯基)-4,6-二(2,4-二羟基苯基)-1,3,5-三嗪的合成方法
JPH11292873A (ja) キノロンカルボン酸誘導体の製造方法およびその中間体
JP3471045B2 (ja) 高純度キノフタロンジカルボン酸の製造方法
JP4321983B2 (ja) 無水ミルタザピンおよびその製法
US2724714A (en) 2 methyl-3 acetyl-4, 5 pyridine dicarboxylic acid, lower alkyl esters thereof and intermediates