IE54053B1 - Resolution of racemic 5-phenyl-2-pentanol - Google Patents

Resolution of racemic 5-phenyl-2-pentanol

Info

Publication number
IE54053B1
IE54053B1 IE2539/82A IE253982A IE54053B1 IE 54053 B1 IE54053 B1 IE 54053B1 IE 2539/82 A IE2539/82 A IE 2539/82A IE 253982 A IE253982 A IE 253982A IE 54053 B1 IE54053 B1 IE 54053B1
Authority
IE
Ireland
Prior art keywords
phenyl
hemiphthalate
brucine
pentanol
liters
Prior art date
Application number
IE2539/82A
Other languages
English (en)
Other versions
IE822539L (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE822539L publication Critical patent/IE822539L/xx
Publication of IE54053B1 publication Critical patent/IE54053B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/20Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • C07D221/12Phenanthridines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE2539/82A 1981-10-22 1982-10-21 Resolution of racemic 5-phenyl-2-pentanol IE54053B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/313,560 US4386205A (en) 1981-10-22 1981-10-22 Resolution of racemic 5-phenyl-2-pentanol

Publications (2)

Publication Number Publication Date
IE822539L IE822539L (en) 1983-04-22
IE54053B1 true IE54053B1 (en) 1989-05-24

Family

ID=23216222

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2539/82A IE54053B1 (en) 1981-10-22 1982-10-21 Resolution of racemic 5-phenyl-2-pentanol

Country Status (7)

Country Link
US (1) US4386205A (https=)
EP (1) EP0078145B1 (https=)
JP (1) JPS58113139A (https=)
DE (1) DE3272348D1 (https=)
DK (1) DK467182A (https=)
GR (1) GR76762B (https=)
IE (1) IE54053B1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524223A (en) * 1984-01-19 1985-06-18 Uop Inc. Resolution of alcohols using amino acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260764A (en) * 1976-12-22 1981-04-07 Pfizer Inc. 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor
DE2832604A1 (de) * 1978-07-21 1980-01-31 Schering Ag Verfahren zur herstellung von 7 alpha -methyl-oestrogenen

Also Published As

Publication number Publication date
EP0078145B1 (en) 1986-07-30
IE822539L (en) 1983-04-22
JPS58113139A (ja) 1983-07-05
JPS629575B2 (https=) 1987-02-28
DE3272348D1 (en) 1986-09-04
EP0078145A1 (en) 1983-05-04
DK467182A (da) 1983-04-23
US4386205A (en) 1983-05-31
GR76762B (https=) 1984-08-31

Similar Documents

Publication Publication Date Title
KR100712003B1 (ko) 펜세린 및 그 유사체의 제조방법
JPS58118571A (ja) オクタヒドロベンゾフロ〔3,2−e〕イソキノリンの製造法およびその中間体
KR20090037445A (ko) 몬테루카스트 정제 방법
EP0078145B1 (en) Resolution of racemic 5-phenyl-2-pentanol
NZ204367A (en) 2-(6-methoxy-2-naphthyl)propionic acid,preparation by resolution method and glucamine resolving agent
CN114409612B (zh) 一种高含量2-氯-5-氯甲基噻唑的制备方法
EP0273321B1 (en) 7-bromo-beta-carboline compound and method for producing same
EP0338895A1 (fr) Nouveaux dérivés hétéroarotinoides, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
US5066826A (en) Process for racemization of optically active 4-phenylbutanoic acid esters
US4987231A (en) Optical resolution method for 3R-(3-carboxybenzyl)-6-(5-fluoro-2-benzothiazolyl)methoxy-4R-chromanol
JPS58159485A (ja) キラルな光学活性化合物
JP3907787B2 (ja) 安息香酸誘導体の製造方法
JPH0468301B2 (https=)
CA1044239A (en) 6-alkoxy-7-hydroxyquinoline-3-carboxylic acids and derivatives thereof
CA1151187A (en) Process for preparing 1-methyl-5-(p-toluoyl)pyrrole-2- acetic acid
CN121872968A (zh) 一种1-Boc-3-氨基吡咯烷-3-甲酸的合成方法
EP0216696A2 (en) Process for preparing cotarnine
CA1151189A (en) Process for preparing: 5-(p-chlorobenzoyl)-1, 4- dimethylpyrrole-2-acetic acid
JP3084577B2 (ja) 光学活性なアトロラクチン酸の製造方法および製造の中間体
CN121627502A (zh) 一种酮洛芬的制备方法
KR900002053B1 (ko) α-아릴-4-치환 피페리디노 알칸올 유도체의 제조방법
US4916226A (en) Optical resolution method for 3S-(3-pyridylmethyl)-6-(2-quinolyl)-methoxy-4S-chromanol
Suzuki et al. Facile cleavage of aryl haloacetates and 2-chloroethyl carboxylic esters with sodium telluride. A one-pot conversion of aryl esters into aryl ethers under aprotic conditions.
JP2893883B2 (ja) アセチレンジカルボン酸エステルの製造方法
CN109096075A (zh) 5-氯-2-羟基-4-甲氧基二苯甲酮的分离提纯方法

Legal Events

Date Code Title Description
MM4A Patent lapsed