JPS5798237A - Novel 2,3-dihydro-indene derivative - Google Patents

Novel 2,3-dihydro-indene derivative

Info

Publication number
JPS5798237A
JPS5798237A JP17505480A JP17505480A JPS5798237A JP S5798237 A JPS5798237 A JP S5798237A JP 17505480 A JP17505480 A JP 17505480A JP 17505480 A JP17505480 A JP 17505480A JP S5798237 A JPS5798237 A JP S5798237A
Authority
JP
Japan
Prior art keywords
dihydro
actions
formulai
compound
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17505480A
Other languages
Japanese (ja)
Other versions
JPS6361933B2 (en
Inventor
Kanji Noda
Akira Nakagawa
Kenji Yamagata
Yoichi Nakajima
Masayoshi Tsuji
Tetsuo Aoki
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP17505480A priority Critical patent/JPS5798237A/en
Publication of JPS5798237A publication Critical patent/JPS5798237A/en
Publication of JPS6361933B2 publication Critical patent/JPS6361933B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NEW MATERIAL:A 2,3-dihydro-indene derivative of formulaI(n is an integer 2W4; R1 and R2 are H, halogen, nitro, amino or lower alkyloxy except when both R1 and R2 are H atoms).
EXAMPLE: 5-Bromo-1-oxo-2,3-dihydro-2-indenepropionic acid.
USE: Useful as a medicine having useful actions such as anti-inflammatory, analgesic, antipyretic, antiallergic actions, inhibitory action on the blood platelet aggregation and antilipemic (cholesterol lowering) actions, and orally administrable.
PROCESS: A compound of formula II is reacted with an alkylaing agent in a solvent, e.g. methanol, in the presence of an alkali, e.g. sodium methylate, for 3W48hr at room temperature or if necessary under heating, and then the resultant reaction mixture is hydrolyzed with a mineral acid to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP17505480A 1980-12-10 1980-12-10 Novel 2,3-dihydro-indene derivative Granted JPS5798237A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17505480A JPS5798237A (en) 1980-12-10 1980-12-10 Novel 2,3-dihydro-indene derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17505480A JPS5798237A (en) 1980-12-10 1980-12-10 Novel 2,3-dihydro-indene derivative

Publications (2)

Publication Number Publication Date
JPS5798237A true JPS5798237A (en) 1982-06-18
JPS6361933B2 JPS6361933B2 (en) 1988-11-30

Family

ID=15989421

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17505480A Granted JPS5798237A (en) 1980-12-10 1980-12-10 Novel 2,3-dihydro-indene derivative

Country Status (1)

Country Link
JP (1) JPS5798237A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5424861A (en) * 1977-07-22 1979-02-24 Hisamitsu Pharmaceut Co Inc Novel 1,2,3,4-tetrahydro-naphthalene derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5424861A (en) * 1977-07-22 1979-02-24 Hisamitsu Pharmaceut Co Inc Novel 1,2,3,4-tetrahydro-naphthalene derivatives

Also Published As

Publication number Publication date
JPS6361933B2 (en) 1988-11-30

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