JPS5785321A - Agent for promoting absorption of acylamino acid, and drug base and preparation for rectal administration containing the same - Google Patents

Agent for promoting absorption of acylamino acid, and drug base and preparation for rectal administration containing the same

Info

Publication number
JPS5785321A
JPS5785321A JP16112180A JP16112180A JPS5785321A JP S5785321 A JPS5785321 A JP S5785321A JP 16112180 A JP16112180 A JP 16112180A JP 16112180 A JP16112180 A JP 16112180A JP S5785321 A JPS5785321 A JP S5785321A
Authority
JP
Japan
Prior art keywords
preparation
acylamino acid
agent
rectal administration
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16112180A
Other languages
Japanese (ja)
Inventor
Senji Kakeya
Kazuhiko Kitao
Kenichi Nishimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyoto Pharmaceutical Industries Ltd
Original Assignee
Kyoto Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries Ltd filed Critical Kyoto Pharmaceutical Industries Ltd
Priority to JP16112180A priority Critical patent/JPS5785321A/en
Priority to US06/246,953 priority patent/US4442090A/en
Publication of JPS5785321A publication Critical patent/JPS5785321A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To provide the titled preparation administrable safely to the rectrum without stimmulating the rectum nor damaging the rectal mucosa, by using at least one compound selected from specific N-acylamino acids and their salts, as a components.
CONSTITUTION: A preparation for rectal administration having excellent transferability of the pharmacologically active substance, is prepared by compounding (A) at least one compound selected from N-acylamino acid having ≥9 total carbon number (having 2W18C acyl group) and their salts[e.g., the compound of formula (R1 is H, alkyl, allyl, etc.; R2 is 2W18C acyl), e.g. N-propionoyl-L- phenylalanine]with (B) an arbitrary pharmacologically active substance[e.g. antibacterial agent having β-lactam ring (e.g. penicillin, etc.), aminoglycoside-type antibiotic substance, polysaccharide-type drug, etc.], and if necessary (C) a base, surface-active agent, antioxidant, preservative, diluent, etc. The amount of the acylamino acid in the composition is 0.5W50wt%.
COPYRIGHT: (C)1982,JPO&Japio
JP16112180A 1980-11-09 1980-11-14 Agent for promoting absorption of acylamino acid, and drug base and preparation for rectal administration containing the same Pending JPS5785321A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP16112180A JPS5785321A (en) 1980-11-14 1980-11-14 Agent for promoting absorption of acylamino acid, and drug base and preparation for rectal administration containing the same
US06/246,953 US4442090A (en) 1980-11-09 1981-03-24 Absorption-promoting compounds, compositions thereof with pharmaceuticals and/or bases for rectal administration and method of use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16112180A JPS5785321A (en) 1980-11-14 1980-11-14 Agent for promoting absorption of acylamino acid, and drug base and preparation for rectal administration containing the same

Publications (1)

Publication Number Publication Date
JPS5785321A true JPS5785321A (en) 1982-05-28

Family

ID=15728995

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16112180A Pending JPS5785321A (en) 1980-11-09 1980-11-14 Agent for promoting absorption of acylamino acid, and drug base and preparation for rectal administration containing the same

Country Status (1)

Country Link
JP (1) JPS5785321A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045122A1 (en) * 1996-05-31 1997-12-04 Kanebo, Limited Suppositories

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56118013A (en) * 1980-02-25 1981-09-16 Teijin Ltd Calcitonin pharmaceutical and its preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56118013A (en) * 1980-02-25 1981-09-16 Teijin Ltd Calcitonin pharmaceutical and its preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045122A1 (en) * 1996-05-31 1997-12-04 Kanebo, Limited Suppositories

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