JPS56104812A - Production of cephalosporin compound preparation for rectal infusion - Google Patents

Production of cephalosporin compound preparation for rectal infusion

Info

Publication number
JPS56104812A
JPS56104812A JP669780A JP669780A JPS56104812A JP S56104812 A JPS56104812 A JP S56104812A JP 669780 A JP669780 A JP 669780A JP 669780 A JP669780 A JP 669780A JP S56104812 A JPS56104812 A JP S56104812A
Authority
JP
Japan
Prior art keywords
fatty acid
active agent
cephalosporin compound
surface active
acid monoglyceride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP669780A
Other languages
Japanese (ja)
Inventor
Ryuzo Okada
Kazue Hasegawa
Minoru Sekine
Tokio Kurasawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP669780A priority Critical patent/JPS56104812A/en
Publication of JPS56104812A publication Critical patent/JPS56104812A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To obtain the titled preparation having high absorbability through the rectum, by mixing or dissolving a specific cephalosporin compound, etc. uniformly in a mixture of a fatty acid monoglyceride and a nonionic surface active agent and/ or a medium fatty acid.
CONSTITUTION: The titled preparation for rectal infusion is prepared by mixing or dissolving a compound of formula (X is O or S; R1 and R2 are substituent groups of a cephalosporin compound; R3 is H or methyl) or its alkali metal salt or organic amine salt homogeneously in a mixture of a fatty acid monoglyceride (e.g. monoacetate) and a nonionic surface active agent (e.g. polyoxyethylenesorbitan monolaurate) and/or a medium fatty acid (e.g. caproic acid). The amount of the additive is 3W50%w/w based on the total amount. The weight ratios of the surface active agent/fatty acid monoglyceride, and the medium fatty acid/fatty acid monoglyceride are pref. 0.5/99.5W70/30, and 2/98W70/30, respectively.
COPYRIGHT: (C)1981,JPO&Japio
JP669780A 1980-01-23 1980-01-23 Production of cephalosporin compound preparation for rectal infusion Pending JPS56104812A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP669780A JPS56104812A (en) 1980-01-23 1980-01-23 Production of cephalosporin compound preparation for rectal infusion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP669780A JPS56104812A (en) 1980-01-23 1980-01-23 Production of cephalosporin compound preparation for rectal infusion

Publications (1)

Publication Number Publication Date
JPS56104812A true JPS56104812A (en) 1981-08-20

Family

ID=11645519

Family Applications (1)

Application Number Title Priority Date Filing Date
JP669780A Pending JPS56104812A (en) 1980-01-23 1980-01-23 Production of cephalosporin compound preparation for rectal infusion

Country Status (1)

Country Link
JP (1) JPS56104812A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588087A (en) * 1981-07-03 1983-01-18 Toyama Chem Co Ltd Novel cephalosporin compound and its intermediate
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
US4816440A (en) * 1985-09-26 1989-03-28 Cetus Corporation Stable formulation of biologically active proteins for parenteral injection
US5190748A (en) * 1988-11-22 1993-03-02 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
US5324721A (en) * 1990-09-28 1994-06-28 Bayer Aktiengesellschaft 3-Substituted cephalosporins, and their use as medicaments
WO2006077856A1 (en) * 2005-01-19 2006-07-27 Nippon Zenyaku Kogyo Co., Ltd. Injection for mastitis

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588087A (en) * 1981-07-03 1983-01-18 Toyama Chem Co Ltd Novel cephalosporin compound and its intermediate
JPH0530836B2 (en) * 1981-07-03 1993-05-11 Toyama Chemical Co Ltd
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
US4816440A (en) * 1985-09-26 1989-03-28 Cetus Corporation Stable formulation of biologically active proteins for parenteral injection
US5190748A (en) * 1988-11-22 1993-03-02 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
US5324721A (en) * 1990-09-28 1994-06-28 Bayer Aktiengesellschaft 3-Substituted cephalosporins, and their use as medicaments
WO2006077856A1 (en) * 2005-01-19 2006-07-27 Nippon Zenyaku Kogyo Co., Ltd. Injection for mastitis

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