JPS56104812A - Production of cephalosporin compound preparation for rectal infusion - Google Patents
Production of cephalosporin compound preparation for rectal infusionInfo
- Publication number
- JPS56104812A JPS56104812A JP669780A JP669780A JPS56104812A JP S56104812 A JPS56104812 A JP S56104812A JP 669780 A JP669780 A JP 669780A JP 669780 A JP669780 A JP 669780A JP S56104812 A JPS56104812 A JP S56104812A
- Authority
- JP
- Japan
- Prior art keywords
- fatty acid
- active agent
- cephalosporin compound
- surface active
- acid monoglyceride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To obtain the titled preparation having high absorbability through the rectum, by mixing or dissolving a specific cephalosporin compound, etc. uniformly in a mixture of a fatty acid monoglyceride and a nonionic surface active agent and/ or a medium fatty acid.
CONSTITUTION: The titled preparation for rectal infusion is prepared by mixing or dissolving a compound of formula (X is O or S; R1 and R2 are substituent groups of a cephalosporin compound; R3 is H or methyl) or its alkali metal salt or organic amine salt homogeneously in a mixture of a fatty acid monoglyceride (e.g. monoacetate) and a nonionic surface active agent (e.g. polyoxyethylenesorbitan monolaurate) and/or a medium fatty acid (e.g. caproic acid). The amount of the additive is 3W50%w/w based on the total amount. The weight ratios of the surface active agent/fatty acid monoglyceride, and the medium fatty acid/fatty acid monoglyceride are pref. 0.5/99.5W70/30, and 2/98W70/30, respectively.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP669780A JPS56104812A (en) | 1980-01-23 | 1980-01-23 | Production of cephalosporin compound preparation for rectal infusion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP669780A JPS56104812A (en) | 1980-01-23 | 1980-01-23 | Production of cephalosporin compound preparation for rectal infusion |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56104812A true JPS56104812A (en) | 1981-08-20 |
Family
ID=11645519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP669780A Pending JPS56104812A (en) | 1980-01-23 | 1980-01-23 | Production of cephalosporin compound preparation for rectal infusion |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56104812A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS588087A (en) * | 1981-07-03 | 1983-01-18 | Toyama Chem Co Ltd | Novel cephalosporin compound and its intermediate |
US4525339A (en) * | 1982-10-15 | 1985-06-25 | Hoffmann-La Roche Inc. | Enteric coated oral dosage form |
US4816440A (en) * | 1985-09-26 | 1989-03-28 | Cetus Corporation | Stable formulation of biologically active proteins for parenteral injection |
US5190748A (en) * | 1988-11-22 | 1993-03-02 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
US5324721A (en) * | 1990-09-28 | 1994-06-28 | Bayer Aktiengesellschaft | 3-Substituted cephalosporins, and their use as medicaments |
WO2006077856A1 (en) * | 2005-01-19 | 2006-07-27 | Nippon Zenyaku Kogyo Co., Ltd. | Injection for mastitis |
-
1980
- 1980-01-23 JP JP669780A patent/JPS56104812A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS588087A (en) * | 1981-07-03 | 1983-01-18 | Toyama Chem Co Ltd | Novel cephalosporin compound and its intermediate |
JPH0530836B2 (en) * | 1981-07-03 | 1993-05-11 | Toyama Chemical Co Ltd | |
US4525339A (en) * | 1982-10-15 | 1985-06-25 | Hoffmann-La Roche Inc. | Enteric coated oral dosage form |
US4816440A (en) * | 1985-09-26 | 1989-03-28 | Cetus Corporation | Stable formulation of biologically active proteins for parenteral injection |
US5190748A (en) * | 1988-11-22 | 1993-03-02 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
US5324721A (en) * | 1990-09-28 | 1994-06-28 | Bayer Aktiengesellschaft | 3-Substituted cephalosporins, and their use as medicaments |
WO2006077856A1 (en) * | 2005-01-19 | 2006-07-27 | Nippon Zenyaku Kogyo Co., Ltd. | Injection for mastitis |
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