JPS5785316A - Preparation of easily absorbable nifedipine preparation - Google Patents
Preparation of easily absorbable nifedipine preparationInfo
- Publication number
- JPS5785316A JPS5785316A JP16095280A JP16095280A JPS5785316A JP S5785316 A JPS5785316 A JP S5785316A JP 16095280 A JP16095280 A JP 16095280A JP 16095280 A JP16095280 A JP 16095280A JP S5785316 A JPS5785316 A JP S5785316A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- water
- nifedipine
- soluble
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title abstract 5
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 title abstract 4
- 229960001597 nifedipine Drugs 0.000 title abstract 4
- 239000008187 granular material Substances 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 2
- 239000006104 solid solution Substances 0.000 abstract 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 230000003179 granulation Effects 0.000 abstract 1
- 238000005469 granulation Methods 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16095280A JPS5785316A (en) | 1980-11-14 | 1980-11-14 | Preparation of easily absorbable nifedipine preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16095280A JPS5785316A (en) | 1980-11-14 | 1980-11-14 | Preparation of easily absorbable nifedipine preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5785316A true JPS5785316A (en) | 1982-05-28 |
| JPH031288B2 JPH031288B2 (enrdf_load_html_response) | 1991-01-10 |
Family
ID=15725741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16095280A Granted JPS5785316A (en) | 1980-11-14 | 1980-11-14 | Preparation of easily absorbable nifedipine preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5785316A (enrdf_load_html_response) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984003440A1 (en) * | 1981-09-14 | 1984-09-13 | Kanebo Ltd | Long-acting nifedipine preparation |
| US4562069A (en) * | 1983-05-21 | 1985-12-31 | Bayer Aktiengesellschaft | Two-phase formulation |
| EP0175671A1 (de) * | 1984-08-23 | 1986-03-26 | Kuhlemann & Co. | Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung |
| JPS61100528A (ja) * | 1984-10-23 | 1986-05-19 | ドクトル レンチユレル アルツナイミツテル ゲ−エムベ−ハ− ウント コ− | ニフエジピン含有薬剤組成物とその製造方法 |
| JPH01249718A (ja) * | 1988-03-30 | 1989-10-05 | Tomoaki Fukuda | マイクロカプセルの製造方法 |
| US4888177A (en) * | 1984-11-05 | 1989-12-19 | Gerhard Gergely | Pharamaceutical preparations in the form of instant granules or tablets and process for their manufacture |
| JP2527107B2 (ja) * | 1991-04-16 | 1996-08-21 | 日本新薬株式会社 | 固体分散体の製造方法 |
| EP1291014A1 (en) * | 2001-09-05 | 2003-03-12 | Shin-Etsu Chemical Co., Ltd. | A process for producing a pharmaceutical solid preparation containing a poorly soluble drug |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005021486A1 (ja) | 2003-08-29 | 2005-03-10 | Japan Tobacco Inc. | エステル誘導体及びその医薬用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5283916A (en) * | 1976-01-02 | 1977-07-13 | Beecham Group Ltd | Medical composition for aural administration |
-
1980
- 1980-11-14 JP JP16095280A patent/JPS5785316A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5283916A (en) * | 1976-01-02 | 1977-07-13 | Beecham Group Ltd | Medical composition for aural administration |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984003440A1 (en) * | 1981-09-14 | 1984-09-13 | Kanebo Ltd | Long-acting nifedipine preparation |
| US4562069A (en) * | 1983-05-21 | 1985-12-31 | Bayer Aktiengesellschaft | Two-phase formulation |
| EP0175671A1 (de) * | 1984-08-23 | 1986-03-26 | Kuhlemann & Co. | Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung |
| JPS61100528A (ja) * | 1984-10-23 | 1986-05-19 | ドクトル レンチユレル アルツナイミツテル ゲ−エムベ−ハ− ウント コ− | ニフエジピン含有薬剤組成物とその製造方法 |
| US4888177A (en) * | 1984-11-05 | 1989-12-19 | Gerhard Gergely | Pharamaceutical preparations in the form of instant granules or tablets and process for their manufacture |
| JPH01249718A (ja) * | 1988-03-30 | 1989-10-05 | Tomoaki Fukuda | マイクロカプセルの製造方法 |
| JP2527107B2 (ja) * | 1991-04-16 | 1996-08-21 | 日本新薬株式会社 | 固体分散体の製造方法 |
| EP1291014A1 (en) * | 2001-09-05 | 2003-03-12 | Shin-Etsu Chemical Co., Ltd. | A process for producing a pharmaceutical solid preparation containing a poorly soluble drug |
| US6872336B2 (en) | 2001-09-05 | 2005-03-29 | Shin-Etsu Chemical Co., Ltd. | Process for producing a pharmaceutical solid preparation containing a poorly soluble drug |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH031288B2 (enrdf_load_html_response) | 1991-01-10 |
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