JPS56160991A - Stabilized dihydrofolate reductase - Google Patents

Stabilized dihydrofolate reductase

Info

Publication number
JPS56160991A
JPS56160991A JP6444980A JP6444980A JPS56160991A JP S56160991 A JPS56160991 A JP S56160991A JP 6444980 A JP6444980 A JP 6444980A JP 6444980 A JP6444980 A JP 6444980A JP S56160991 A JPS56160991 A JP S56160991A
Authority
JP
Japan
Prior art keywords
dihydrofolate reductase
freeze
dried
stabilized
dissolved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6444980A
Other languages
Japanese (ja)
Other versions
JPH0137118B2 (en
Inventor
Atsuyuki Kato
Tadashi Hase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP6444980A priority Critical patent/JPS56160991A/en
Publication of JPS56160991A publication Critical patent/JPS56160991A/en
Publication of JPH0137118B2 publication Critical patent/JPH0137118B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To improve the stability of the titled dihydrofolate reductase, by adding albumin to the titled reagent used for determining the concentration of a folic acid antagonistic agent Methotrexate in blood, and freeze-drying the resultant solution.
CONSTITUTION: Dihydrofolate reductase is dissolved in a buffer solution and prepared, and albumin is added and dissolved in the solution. The aimed dosage is divided and introduced into the respective vials in a cold room, previously freeze- dried and then freeze-dried to give a freeze-dried dihydrofolate reductase to be used as a reagent.
COPYRIGHT: (C)1981,JPO&Japio
JP6444980A 1980-05-15 1980-05-15 Stabilized dihydrofolate reductase Granted JPS56160991A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6444980A JPS56160991A (en) 1980-05-15 1980-05-15 Stabilized dihydrofolate reductase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6444980A JPS56160991A (en) 1980-05-15 1980-05-15 Stabilized dihydrofolate reductase

Publications (2)

Publication Number Publication Date
JPS56160991A true JPS56160991A (en) 1981-12-11
JPH0137118B2 JPH0137118B2 (en) 1989-08-04

Family

ID=13258566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6444980A Granted JPS56160991A (en) 1980-05-15 1980-05-15 Stabilized dihydrofolate reductase

Country Status (1)

Country Link
JP (1) JPS56160991A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62253378A (en) * 1986-04-24 1987-11-05 Kokusai Shiyaku Kk Stabilization of creatine kinase
US5523223A (en) * 1992-03-13 1996-06-04 Forschungszentrum Julich Gmbh Ketoester reductase for conversion of keto acid esters to optically active hydroxy acid esters
US11604026B2 (en) 2019-03-14 2023-03-14 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
US11634257B2 (en) 2017-10-09 2023-04-25 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLIN CHEM=1980 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62253378A (en) * 1986-04-24 1987-11-05 Kokusai Shiyaku Kk Stabilization of creatine kinase
JP2575648B2 (en) * 1986-04-24 1997-01-29 国際試薬株式会社 Method for stabilizing creatine kinase
US5523223A (en) * 1992-03-13 1996-06-04 Forschungszentrum Julich Gmbh Ketoester reductase for conversion of keto acid esters to optically active hydroxy acid esters
US11634257B2 (en) 2017-10-09 2023-04-25 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
US11604026B2 (en) 2019-03-14 2023-03-14 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
US11609043B2 (en) 2019-03-14 2023-03-21 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use
US11609042B2 (en) 2019-03-14 2023-03-21 Terumo Bct Biotechnologies, Llc Multi-part lyophilization container and method of use
US11740019B2 (en) 2019-03-14 2023-08-29 Terumo Bct Biotechnologies, Llc Lyophilization loading tray assembly and system
US11747082B2 (en) 2019-03-14 2023-09-05 Terumo Bct Biotechnologies, Llc Multi-part lyophilization container and method of use
US11815311B2 (en) 2019-03-14 2023-11-14 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use

Also Published As

Publication number Publication date
JPH0137118B2 (en) 1989-08-04

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