JPS56160991A - Stabilized dihydrofolate reductase - Google Patents
Stabilized dihydrofolate reductaseInfo
- Publication number
- JPS56160991A JPS56160991A JP6444980A JP6444980A JPS56160991A JP S56160991 A JPS56160991 A JP S56160991A JP 6444980 A JP6444980 A JP 6444980A JP 6444980 A JP6444980 A JP 6444980A JP S56160991 A JPS56160991 A JP S56160991A
- Authority
- JP
- Japan
- Prior art keywords
- dihydrofolate reductase
- freeze
- dried
- stabilized
- dissolved
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To improve the stability of the titled dihydrofolate reductase, by adding albumin to the titled reagent used for determining the concentration of a folic acid antagonistic agent Methotrexate in blood, and freeze-drying the resultant solution.
CONSTITUTION: Dihydrofolate reductase is dissolved in a buffer solution and prepared, and albumin is added and dissolved in the solution. The aimed dosage is divided and introduced into the respective vials in a cold room, previously freeze- dried and then freeze-dried to give a freeze-dried dihydrofolate reductase to be used as a reagent.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6444980A JPS56160991A (en) | 1980-05-15 | 1980-05-15 | Stabilized dihydrofolate reductase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6444980A JPS56160991A (en) | 1980-05-15 | 1980-05-15 | Stabilized dihydrofolate reductase |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56160991A true JPS56160991A (en) | 1981-12-11 |
JPH0137118B2 JPH0137118B2 (en) | 1989-08-04 |
Family
ID=13258566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6444980A Granted JPS56160991A (en) | 1980-05-15 | 1980-05-15 | Stabilized dihydrofolate reductase |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56160991A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62253378A (en) * | 1986-04-24 | 1987-11-05 | Kokusai Shiyaku Kk | Stabilization of creatine kinase |
US5523223A (en) * | 1992-03-13 | 1996-06-04 | Forschungszentrum Julich Gmbh | Ketoester reductase for conversion of keto acid esters to optically active hydroxy acid esters |
US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
-
1980
- 1980-05-15 JP JP6444980A patent/JPS56160991A/en active Granted
Non-Patent Citations (1)
Title |
---|
CLIN CHEM=1980 * |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62253378A (en) * | 1986-04-24 | 1987-11-05 | Kokusai Shiyaku Kk | Stabilization of creatine kinase |
JP2575648B2 (en) * | 1986-04-24 | 1997-01-29 | 国際試薬株式会社 | Method for stabilizing creatine kinase |
US5523223A (en) * | 1992-03-13 | 1996-06-04 | Forschungszentrum Julich Gmbh | Ketoester reductase for conversion of keto acid esters to optically active hydroxy acid esters |
US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
US11609043B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
US11609042B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
US11740019B2 (en) | 2019-03-14 | 2023-08-29 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
US11747082B2 (en) | 2019-03-14 | 2023-09-05 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
US11815311B2 (en) | 2019-03-14 | 2023-11-14 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
Also Published As
Publication number | Publication date |
---|---|
JPH0137118B2 (en) | 1989-08-04 |
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